JP7237344B2 - インフルエンザウイルス血球凝集素タンパク質及びその使用 - Google Patents

インフルエンザウイルス血球凝集素タンパク質及びその使用 Download PDF

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JP7237344B2
JP7237344B2 JP2018565670A JP2018565670A JP7237344B2 JP 7237344 B2 JP7237344 B2 JP 7237344B2 JP 2018565670 A JP2018565670 A JP 2018565670A JP 2018565670 A JP2018565670 A JP 2018565670A JP 7237344 B2 JP7237344 B2 JP 7237344B2
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amino acid
virus
influenza
acid residues
yamagata
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JP2019521674A (ja
JP2019521674A5 (OSRAM
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パレセ ピーター
ガルシア‐サストレ アドルフォ
クラムメル フロリアン
エルムレル ミーガン
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アイカーン スクール オブ メディシン アット マウント サイナイ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16271—Demonstrated in vivo effect

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  • Communicable Diseases (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2018565670A 2016-06-15 2017-06-14 インフルエンザウイルス血球凝集素タンパク質及びその使用 Active JP7237344B2 (ja)

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JP2022133019A JP2022176993A (ja) 2016-06-15 2022-08-24 インフルエンザウイルス血球凝集素タンパク質及びその使用

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US201662350701P 2016-06-15 2016-06-15
US62/350,701 2016-06-15
US201662355679P 2016-06-28 2016-06-28
US62/355,679 2016-06-28
PCT/US2017/037384 WO2017218624A1 (en) 2016-06-15 2017-06-14 Influenza virus hemagglutinin proteins and uses thereof

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JP2019521674A JP2019521674A (ja) 2019-08-08
JP2019521674A5 JP2019521674A5 (OSRAM) 2020-07-30
JP7237344B2 true JP7237344B2 (ja) 2023-03-13

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EP (1) EP3471767A4 (OSRAM)
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CN (1) CN109641041A (OSRAM)
BR (1) BR112018075032A2 (OSRAM)
CA (1) CA3023143A1 (OSRAM)
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JP2013526849A (ja) 2010-03-30 2013-06-27 モウント シナイ スクール オフ メディシネ インフルエンザウイルスワクチン及びその使用
BR112014006694A2 (pt) 2011-09-20 2020-11-17 Mount Sinai School Of Medicine vacinas contra o vírus influenza e usos dessas
JP2016508133A (ja) 2012-12-18 2016-03-17 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルスワクチン及びその使用
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
US10736956B2 (en) 2015-01-23 2020-08-11 Icahn School Of Medicine At Mount Sinai Influenza virus vaccination regimens
JP7237344B2 (ja) 2016-06-15 2023-03-13 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルス血球凝集素タンパク質及びその使用
EP3606555A4 (en) 2017-04-07 2021-08-04 Icahn School of Medicine at Mount Sinai INFLUENZA VIRUS TYPE B ANTI-NEURAMINIDASE ANTIBODIES AND THEIR USES
KR101964044B1 (ko) * 2018-03-14 2019-04-02 인제대학교 산학협력단 재조합 아데노바이러스를 이용한 다가형 인플루엔자 생백신 플랫폼
WO2019246363A1 (en) 2018-06-21 2019-12-26 Icahn School Of Medicine At Mount Sinai Mosaic influenza virus hemagglutinin polypeptides and uses thereof
WO2020232426A1 (en) * 2019-05-16 2020-11-19 Vanderbilt University Peptide vaccine based on a new universal influenza a hemagglutinin head domain epitope and human monoclonal antibodies binding thereto
US20220249652A1 (en) * 2019-06-26 2022-08-11 Icahn School Of Medicine At Mount Sinai Influenza virus neuraminidase and uses thereof
BR112022007923A2 (pt) * 2019-10-28 2022-07-26 Regeneron Pharma Anticorpo recombinante isolado ou fragmento de ligação ao antígeno deste, composição farmacêutica, molécula de polinucleotídeo, vetor, célula, e, método para prevenir, tratar ou melhorar pelo menos um sintoma da infecção por influenza
CN119452088A (zh) * 2022-05-31 2025-02-14 Vlp治疗日本公司 修饰疫苗设计开发
CN116284432A (zh) * 2022-09-09 2023-06-23 中山大学·深圳 一种乙型流感病毒重组蛋白疫苗及其制备方法
WO2025072921A1 (en) * 2023-09-29 2025-04-03 Icahn School Of Medicine At Mount Sinai Chimeric influenza virus hemagglutinin mrna-based vaccines and uses thereof
WO2025184346A1 (en) * 2024-02-29 2025-09-04 Icahn School Of Medicine At Mount Sinai Immunogenic compositions containing inactivated influenza b virus and cpg oligonucleotide adjuvant and uses thereof

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