JP7080213B2 - 新規抗ｐｄ－ｌ１抗体 - Google Patents
新規抗ｐｄ－ｌ１抗体 Download PDFInfo
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- JP7080213B2 JP7080213B2 JP2019500712A JP2019500712A JP7080213B2 JP 7080213 B2 JP7080213 B2 JP 7080213B2 JP 2019500712 A JP2019500712 A JP 2019500712A JP 2019500712 A JP2019500712 A JP 2019500712A JP 7080213 B2 JP7080213 B2 JP 7080213B2
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| CN115925943A (zh) * | 2017-12-27 | 2023-04-07 | 信达生物制药(苏州)有限公司 | 抗pd-l1抗体及其用途 |
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| US12263234B2 (en) * | 2019-01-23 | 2025-04-01 | Tayu Huaxia Biotech Medical Group Co., Ltd. | Anti-PD-L1 diabodies and the use thereof |
| WO2020151759A1 (zh) | 2019-01-25 | 2020-07-30 | 正大天晴药业集团股份有限公司 | 治疗肿瘤的联用药物组合物 |
| CN109929037B (zh) * | 2019-04-01 | 2023-03-17 | 华博生物医药技术（上海）有限公司 | 针对程序性死亡配体的结合物及其应用 |
| EP3976090A1 (en) | 2019-05-24 | 2022-04-06 | Pfizer Inc. | Combination therapies using cdk inhibitors |
| CN114127315A (zh) * | 2019-05-30 | 2022-03-01 | 百时美施贵宝公司 | 鉴定适合于免疫肿瘤学(i-o)疗法的受试者的方法 |
| CN110194798A (zh) * | 2019-05-31 | 2019-09-03 | 杭州科兴生物科技有限公司 | 抗pd-l1单克隆抗体、片段及其医药用途 |
| EP3990116A1 (en) | 2019-06-28 | 2022-05-04 | Gensun Biopharma Inc. | ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFß1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD |
| GB201910138D0 (en) * | 2019-07-15 | 2019-08-28 | Capella Bioscience Ltd | Anti-pd-l1 antibodies |
| CA3157516A1 (en) * | 2019-11-08 | 2021-05-14 | Xinyan Zhao | Anti-human programmed cell death ligand-1 (pd-l1) antibody and use thereof |
| WO2021197358A1 (zh) * | 2020-03-31 | 2021-10-07 | 普米斯生物技术(珠海)有限公司 | 一种抗pd-l1和pd-l2抗体及其衍生物和用途 |
| WO2022022503A1 (en) * | 2020-07-28 | 2022-02-03 | Lepu Biopharma Co., Ltd. | Bifunctional molecules targeting pd-l1 and tgf-beta |
| EP4192884A4 (en) * | 2020-08-04 | 2025-04-09 | Exelixis, Inc. | PD-L1-BINDING AGENTS AND USES THEREOF |
| CN111929447B (zh) * | 2020-09-24 | 2021-02-26 | 菁良基因科技(深圳)有限公司 | 一种pd-l1免疫组织化学参考品及其制备方法和应用 |
| KR20230110546A (ko) * | 2020-11-18 | 2023-07-24 | 쑤저우 트랜스센타 테라퓨틱스 컴퍼니 리미티드 | 이작용성 분자 |
| CN112285366B (zh) * | 2020-12-25 | 2021-06-08 | 南京广祺医药科技有限公司 | 一种测定血清中双特异性抗体BsAb的ELISA方法及应用 |
| WO2023001987A2 (en) | 2021-07-22 | 2023-01-26 | University Of Dundee | Therapeutic muteins |
| CN115521378B (zh) * | 2021-07-23 | 2023-12-22 | 南京吉盛澳玛生物医药有限公司 | Pd-l1抗体及其用途 |
| US20240382411A1 (en) * | 2021-09-18 | 2024-11-21 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Composition comprising pd-l1 antigen-binding fragment and use thereof |
| TW202327595A (zh) | 2021-10-05 | 2023-07-16 | 美商輝瑞大藥廠 | 用於治療癌症之氮雜內醯胺化合物的組合 |
| WO2023079428A1 (en) | 2021-11-03 | 2023-05-11 | Pfizer Inc. | Combination therapies using tlr7/8 agonist |
| TW202333785A (zh) * | 2021-11-16 | 2023-09-01 | 中國大陸商蘇州創勝醫藥集團有限公司 | Ｃｌａｕｄｉｎ１８．２拮抗劑和ｐｄ－１／ｐｄ－ｌ１軸抑制劑的組合療法 |
| WO2023221936A1 (zh) | 2022-05-17 | 2023-11-23 | 苏州创胜医药集团有限公司 | 双功能蛋白质及其制剂和用途 |
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| JP2022068161A (ja) | 2022-05-09 |
| JP2023171733A (ja) | 2023-12-05 |
| CN108779180A (zh) | 2018-11-09 |
| RU2018124602A3 (enExample) | 2020-03-06 |
| EP3433277A1 (en) | 2019-01-30 |
| RU2744959C2 (ru) | 2021-03-17 |
| JP2019516394A (ja) | 2019-06-20 |
| CN108779180B (zh) | 2020-10-16 |
| RU2021106377A3 (enExample) | 2021-12-28 |
| CA3007135A1 (en) | 2017-09-28 |
| CN111363041B (zh) | 2022-02-22 |
| JP7345578B2 (ja) | 2023-09-15 |
| US11753473B2 (en) | 2023-09-12 |
| JP7624484B2 (ja) | 2025-01-30 |
| KR20180127971A (ko) | 2018-11-30 |
| EP3433277A4 (en) | 2020-06-17 |
| US10822416B2 (en) | 2020-11-03 |
| US20210009693A1 (en) | 2021-01-14 |
| WO2017161976A1 (en) | 2017-09-28 |
| CN111363041A (zh) | 2020-07-03 |
| US20190330348A1 (en) | 2019-10-31 |
| RU2018124602A (ru) | 2020-01-14 |
| RU2021106377A (ru) | 2021-03-31 |
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