JP6553059B2 - Ｈｂｖ感染の治療のための併用療法 - Google Patents
Ｈｂｖ感染の治療のための併用療法 Download PDFInfo
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- JP6553059B2 JP6553059B2 JP2016548313A JP2016548313A JP6553059B2 JP 6553059 B2 JP6553059 B2 JP 6553059B2 JP 2016548313 A JP2016548313 A JP 2016548313A JP 2016548313 A JP2016548313 A JP 2016548313A JP 6553059 B2 JP6553059 B2 JP 6553059B2
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- interferon
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| RS57999B1 (sr) | 2013-05-17 | 2019-01-31 | Janssen Sciences Ireland Uc | Derivati sulfamoiltiofenamida i njihova primena kao lekovi za tretman hepatitisa b |
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| MX368158B (es) | 2013-10-23 | 2019-09-20 | Janssen Sciences Ireland Uc | Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
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| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| ES2792848T3 (es) | 2014-02-05 | 2020-11-12 | Novira Therapeutics Inc | Politerapia para el tratamiento de infecciones por VHB |
| CN110483484A (zh) | 2014-02-06 | 2019-11-22 | 爱尔兰詹森科学公司 | 氨磺酰基吡咯酰胺衍生物及其作为药物用于治疗乙型肝炎的用途 |
| JP2018510159A (ja) | 2015-03-19 | 2018-04-12 | ノヴィラ・セラピューティクス・インコーポレイテッド | アゾカン及びアゾナン誘導体及びｂ型肝炎感染症の治療法 |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| CA3000197A1 (en) | 2015-09-29 | 2017-04-06 | Novira Therapeutics, Inc. | Crystalline forms of a hepatitis b antiviral agent |
| BR112018009009A8 (pt) * | 2015-11-03 | 2019-02-26 | Hoffmann La Roche | terapia combinada de um inibidor de formação de capsídeo hbv e um interferon |
| SG11201808949SA (en) | 2016-04-15 | 2018-11-29 | Novira Therapeutics Inc | Combinations and methods comprising a capsid assembly inhibitor |
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| AU2019235522A1 (en) | 2018-03-14 | 2020-09-03 | Janssen Sciences Ireland Unlimited Company | Capsid assembly modulator dosing regimen |
| EP3597637A1 (en) | 2018-07-19 | 2020-01-22 | Irbm S.P.A. | Inhibitors of hepatitis b virus |
| EP3597653A1 (en) | 2018-07-19 | 2020-01-22 | Irbm S.P.A. | Cyclic inhibitors of hepatitis b virus |
| EP3608326A1 (en) | 2018-08-10 | 2020-02-12 | Irbm S.P.A. | Tricyclic inhibitors of hepatitis b virus |
| AU2020223865A1 (en) | 2019-02-22 | 2021-07-15 | Janssen Sciences Ireland Unlimited Company | Amide derivatives useful in the treatment of HBV infection or HBV-induced diseases |
| AR119732A1 (es) | 2019-05-06 | 2022-01-05 | Janssen Sciences Ireland Unlimited Co | Derivados de amida útiles en el tratamiento de la infección por vhb o de enfermedades inducidas por vhb |
| EP3741762A1 (en) | 2019-05-23 | 2020-11-25 | Irbm S.P.A. | Oxalamido-substituted tricyclic inhibitors of hepatitis b virus |
| UY38705A (es) | 2019-05-23 | 2020-12-31 | Irbm S P A | Inhibidores tricíclicos sustituidos con oxalamido del virus de hepatitis b |
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| JP2024537830A (ja) * | 2021-10-08 | 2024-10-16 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | カプシドタンパク質阻害剤と逆転写酵素阻害剤とを含む医薬組合せ |
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| RU2682672C2 (ru) | 2014-03-28 | 2019-03-20 | Саншайн Лейк Фарма Ко., Лтд. | Соединения дигидропиримидина и их применение в фармацевтических препаратах |
| CA2948580A1 (en) * | 2014-05-09 | 2015-11-12 | Adam Zlotnick | Methods and compositions for treating hepatitis b virus infections |
| KR102428878B1 (ko) | 2014-05-30 | 2022-08-04 | 치루 파머수티컬 컴퍼니 리미티드 | Hbv억제제인 디히드로피리미도 축합환 유도체 |
| WO2016089990A1 (en) | 2014-12-02 | 2016-06-09 | Novira Therapeutics, Inc. | Sulfide alkyl and pyridyl reverse sulfonamide compounds for hbv treatment |
| AU2015373996B2 (en) | 2014-12-30 | 2020-10-08 | Novira Therapeutics, Inc. | Derivatives and methods of treating hepatitis B infections |
| MA41338B1 (fr) | 2015-01-16 | 2019-07-31 | Hoffmann La Roche | Composés de pyrazine pour le traitement de maladies infectieuses |
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| US10273228B2 (en) | 2015-04-17 | 2019-04-30 | Indiana University Research And Technology Corporation | Hepatitis B viral assembly effectors |
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| CA3000197A1 (en) | 2015-09-29 | 2017-04-06 | Novira Therapeutics, Inc. | Crystalline forms of a hepatitis b antiviral agent |
| SG11201808949SA (en) | 2016-04-15 | 2018-11-29 | Novira Therapeutics Inc | Combinations and methods comprising a capsid assembly inhibitor |
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| CA2936947A1 (en) | 2015-08-13 |
| EP3102225A1 (en) | 2016-12-14 |
| CN106232136A (zh) | 2016-12-14 |
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| JP2017505314A (ja) | 2017-02-16 |
| AU2015214096A1 (en) | 2016-09-01 |
| EP3102225A4 (en) | 2017-11-01 |
| US20190209541A1 (en) | 2019-07-11 |
| AU2015214096B2 (en) | 2021-02-11 |
| MX383447B (es) | 2025-03-14 |
| US10213420B2 (en) | 2019-02-26 |
| US20170182021A1 (en) | 2017-06-29 |
| EP3102225B1 (en) | 2020-03-25 |
| US10632112B2 (en) | 2020-04-28 |
| HK1225968A1 (en) | 2017-09-22 |
| KR20160128305A (ko) | 2016-11-07 |
| RU2702109C1 (ru) | 2019-10-04 |
| WO2015120178A1 (en) | 2015-08-13 |
| ES2792848T3 (es) | 2020-11-12 |
| MX2016009449A (es) | 2016-10-13 |
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