JP6513782B2 - 結合部材 - Google Patents
結合部材 Download PDFInfo
- Publication number
- JP6513782B2 JP6513782B2 JP2017247503A JP2017247503A JP6513782B2 JP 6513782 B2 JP6513782 B2 JP 6513782B2 JP 2017247503 A JP2017247503 A JP 2017247503A JP 2017247503 A JP2017247503 A JP 2017247503A JP 6513782 B2 JP6513782 B2 JP 6513782B2
- Authority
- JP
- Japan
- Prior art keywords
- core
- yarn
- coupling member
- active substance
- thread
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000008878 coupling Effects 0.000 title claims description 64
- 238000010168 coupling process Methods 0.000 title claims description 64
- 238000005859 coupling reaction Methods 0.000 title claims description 64
- 239000000463 material Substances 0.000 claims abstract description 67
- 150000003839 salts Chemical class 0.000 claims description 40
- 239000013078 crystal Substances 0.000 claims description 24
- 229920001296 polysiloxane Polymers 0.000 claims description 21
- 239000002357 osmotic agent Substances 0.000 claims description 12
- 238000009792 diffusion process Methods 0.000 claims description 11
- 230000003204 osmotic effect Effects 0.000 claims description 11
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 11
- 229920001971 elastomer Polymers 0.000 claims description 9
- 238000009826 distribution Methods 0.000 claims description 8
- 239000000806 elastomer Substances 0.000 claims description 8
- 239000002861 polymer material Substances 0.000 claims description 4
- 238000013270 controlled release Methods 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 239000011149 active material Substances 0.000 claims 2
- 230000001629 suppression Effects 0.000 claims 1
- 239000003356 suture material Substances 0.000 abstract description 9
- 239000011162 core material Substances 0.000 description 93
- 239000012528 membrane Substances 0.000 description 43
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 27
- 229920000642 polymer Polymers 0.000 description 24
- 230000008602 contraction Effects 0.000 description 19
- 239000013543 active substance Substances 0.000 description 18
- 230000008961 swelling Effects 0.000 description 17
- 210000002435 tendon Anatomy 0.000 description 16
- 238000000034 method Methods 0.000 description 15
- 210000001519 tissue Anatomy 0.000 description 15
- 239000007788 liquid Substances 0.000 description 14
- 239000002245 particle Substances 0.000 description 13
- 239000011780 sodium chloride Substances 0.000 description 13
- 230000008859 change Effects 0.000 description 12
- 238000005469 granulation Methods 0.000 description 12
- 230000003179 granulation Effects 0.000 description 12
- 238000012360 testing method Methods 0.000 description 12
- 210000000988 bone and bone Anatomy 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 230000008569 process Effects 0.000 description 9
- 239000000758 substrate Substances 0.000 description 9
- 238000000576 coating method Methods 0.000 description 8
- 238000002513 implantation Methods 0.000 description 8
- 238000000338 in vitro Methods 0.000 description 8
- 238000001727 in vivo Methods 0.000 description 8
- 210000003041 ligament Anatomy 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 238000007906 compression Methods 0.000 description 7
- 239000000314 lubricant Substances 0.000 description 7
- 230000006835 compression Effects 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 210000000056 organ Anatomy 0.000 description 6
- 210000004872 soft tissue Anatomy 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000004952 Polyamide Substances 0.000 description 5
- 230000009471 action Effects 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 5
- 210000003195 fascia Anatomy 0.000 description 5
- 239000000499 gel Substances 0.000 description 5
- 239000007943 implant Substances 0.000 description 5
- 229920002647 polyamide Polymers 0.000 description 5
- 239000004814 polyurethane Substances 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 230000007547 defect Effects 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 230000035515 penetration Effects 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920000728 polyester Polymers 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 3
- 230000002776 aggregation Effects 0.000 description 3
- 238000004220 aggregation Methods 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000005022 packaging material Substances 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 229920000098 polyolefin Polymers 0.000 description 3
- 229920002635 polyurethane Polymers 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 208000007101 Muscle Cramp Diseases 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 229940072056 alginate Drugs 0.000 description 2
- 229920000615 alginic acid Polymers 0.000 description 2
- 235000010443 alginic acid Nutrition 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229920002988 biodegradable polymer Polymers 0.000 description 2
- 239000004621 biodegradable polymer Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000000845 cartilage Anatomy 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229920006237 degradable polymer Polymers 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- -1 dextran Polysaccharides Chemical class 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000009477 glass transition Effects 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000013618 particulate matter Substances 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 102000005962 receptors Human genes 0.000 description 2
- 108020003175 receptors Proteins 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 210000000513 rotator cuff Anatomy 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- VIESAWGOYVNHLV-UHFFFAOYSA-N 1,3-dihydropyrrol-2-one Chemical compound O=C1CC=CN1 VIESAWGOYVNHLV-UHFFFAOYSA-N 0.000 description 1
- 206010002329 Aneurysm Diseases 0.000 description 1
- LVRCEUVOXCJYSV-UHFFFAOYSA-N CN(C)S(=O)=O Chemical compound CN(C)S(=O)=O LVRCEUVOXCJYSV-UHFFFAOYSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004988 Nematic liquid crystal Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920000331 Polyhydroxybutyrate Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 210000001361 achilles tendon Anatomy 0.000 description 1
- 210000000142 acromioclavicular joint Anatomy 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 210000003423 ankle Anatomy 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229920003235 aromatic polyamide Polymers 0.000 description 1
- 238000000418 atomic force spectrum Methods 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000000013 bile duct Anatomy 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036983 biotransformation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 210000004439 collateral ligament Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000004035 construction material Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 230000001085 cytostatic effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 210000001513 elbow Anatomy 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000000329 molecular dynamics simulation Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000005015 poly(hydroxybutyrate) Substances 0.000 description 1
- 229920000218 poly(hydroxyvalerate) Polymers 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 description 1
- 229920003223 poly(pyromellitimide-1,4-diphenyl ether) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 239000000622 polydioxanone Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 229920000431 shape-memory polymer Polymers 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000002522 swelling effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06166—Sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C61/00—Shaping by liberation of internal stresses; Making preforms having internal stresses; Apparatus therefor
- B29C61/06—Making preforms having internal stresses, e.g. plastic memory
- B29C61/0608—Making preforms having internal stresses, e.g. plastic memory characterised by the configuration or structure of the preforms
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
Description
開始点d0における糸直径 7×10-4m
開始角α 60°
張力方向に対する糸角度β 90−α°
濃度本体Cblood 0.296mol/l
飽和濃度(NaCl)Csaturation 6.15mol/l
11 コア
12 ジャケット(当初)
13 結合構成部(メッシュ)
14 結節
15 矢印
16 ジャケット(変形後)
20 結合部材の一部
22 ジャケット(当初)
26 ジャケット(変形後、分解状態)
30 結合部材
31 分子
33 解放の方向
34 矢印
40 結合部材
11 コア
42 ジャケット(当初)
43 メッシュ
44 角度(最初)
45 角度(その後)
46 メッシュ
47 塩結晶
48 活性物質が充填された小胞
49 活性物質
50 結合部材
51 基材
52 糸分子(最初)
53 糸分子(その後)
61 結果として生じる直径の変化
62 結果として生じる長さの変化
63 結果として生じる体積の変化
64 糸角度範囲
65 結果として生じる力の変化
71 時間
72 糸張力
73 切り換え ピンと張った状態←→緩んだ状態
74 従来の糸
75 緩み
76 降下
77 更なる緩み
84 本発明に係る糸
85 引張り
86 降下
87 更なる引張り
160 糸
161 コア
162 メッシュエンベロープ
163 エンベロープフィラメント
164 ステッチ糸
165 基質
166 塩結晶
170 糸
171 コーティング
175 食塩水
176 塩結晶
177 チューブ膜
180 糸
181 外側膜
183 モノフィラメント
185 浸透液体を伴う空間
186 塩結晶
187 活性物質を伴う小胞
188 活性物質溶液
190 糸
191 コア膜
195 コアとエンベロープとの間の空間
200 糸
201 マルチコア膜
301 時間
302 上昇する力
303 曲線
401 造粒
402 収縮
403 シリコーン中の塩含有量が高い場合の曲線
404 シリコーン中の塩含有量が低い場合の曲線
501 最初の収縮501(パーセント/日)
502 塩に対するシリコーンの重量比率
503 造粒(ミクロン)
504 三次元曲線
601 時間(日)
602 収縮(パーセント)
603−606 異なる糸における曲線
Claims (10)
- 身体内で用いられる長手方向に沿って細長い結合部材であって、
前記長手方向に実質的に沿って延在するコアであって、ポリマー材料、および前記ポリマー材料中に分散された浸透活性物質を含み、前記浸透活性物質は、前記コアの内部と外部との間の前記浸透活性物質の濃度差によって浸透圧を生じさせる、コアと、
前記コアの少なくとも一部を前記長手方向に沿って取り囲むスリーブであって、前記スリーブは、前記スリーブの両端の間の前記長手方向の長さを画定し、少なくとも1本の糸を含み、前記少なくとも1本の糸は、前記長手方向に対して交差する角度を画定する、スリーブとを含み、
前記浸透活性物質は、前記ポリマー材料の中に可変の分布密度を有し、前記可変の分布密度は、前記長手方向に対して径方向に変化する、結合部材。 - 前記ポリマー材料は、エラストマーを含む、請求項1に記載の結合部材。
- 前記エラストマーは、熱可塑性エラストマー、または架橋エラストマーを含む、請求項2に記載の結合部材。
- 前記エラストマーは、シリコーンを含み、前記浸透活性物質は、塩結晶を含む、請求項2に記載の結合部材。
- 前記コアは、前記浸透活性物質の制御された放出を与えるように構成されている、請求項1に記載の結合部材。
- 前記コアは、押し出し成形されている、請求項2に記載の結合部材。
- 前記コアを取り囲む拡散抑制膜をさらに含み、前記膜は、エラストマー膜である、請求項2に記載の結合部材。
- 前記スリーブは、前記コアの流体膨張により、少なくとも1つの前記交差の角度が増加するように前記コアに沿って摺動するように構成されている、請求項1に記載の結合部材。
- 前記浸透活性物質は、前記コアの内部の小胞内に配置されている、請求項1に記載の結合部材。
- 前記浸透活性物質は、前記ポリマー材料中に溶解されている、請求項1に記載の結合部材。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH0834/05 | 2005-05-04 | ||
CH8342005 | 2005-05-04 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016255502A Division JP6422934B2 (ja) | 2005-05-04 | 2016-12-28 | 結合部材 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018075408A JP2018075408A (ja) | 2018-05-17 |
JP6513782B2 true JP6513782B2 (ja) | 2019-05-15 |
Family
ID=37308340
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008509452A Active JP5204647B2 (ja) | 2005-05-04 | 2006-05-04 | 結合部材 |
JP2012271669A Active JP6113485B2 (ja) | 2005-05-04 | 2012-12-12 | 結合部材 |
JP2015126366A Active JP6023277B2 (ja) | 2005-05-04 | 2015-06-24 | 結合部材 |
JP2016255502A Active JP6422934B2 (ja) | 2005-05-04 | 2016-12-28 | 結合部材 |
JP2017247503A Active JP6513782B2 (ja) | 2005-05-04 | 2017-12-25 | 結合部材 |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008509452A Active JP5204647B2 (ja) | 2005-05-04 | 2006-05-04 | 結合部材 |
JP2012271669A Active JP6113485B2 (ja) | 2005-05-04 | 2012-12-12 | 結合部材 |
JP2015126366A Active JP6023277B2 (ja) | 2005-05-04 | 2015-06-24 | 結合部材 |
JP2016255502A Active JP6422934B2 (ja) | 2005-05-04 | 2016-12-28 | 結合部材 |
Country Status (15)
Country | Link |
---|---|
US (6) | US8870915B2 (ja) |
EP (1) | EP1973582B1 (ja) |
JP (5) | JP5204647B2 (ja) |
KR (2) | KR101387070B1 (ja) |
CN (1) | CN101193665B (ja) |
AT (1) | ATE523214T1 (ja) |
AU (1) | AU2006243216B2 (ja) |
BR (1) | BRPI0612350B8 (ja) |
CA (1) | CA2608107C (ja) |
IL (1) | IL186571A (ja) |
MX (1) | MX2007013633A (ja) |
NO (1) | NO20075359L (ja) |
RU (1) | RU2404821C2 (ja) |
WO (1) | WO2006117398A2 (ja) |
ZA (1) | ZA200709837B (ja) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007013633A (es) * | 2005-05-04 | 2008-03-13 | Etech Ag | Elemento de union rigido, de contraccion lenta, para medicina y otros usos. |
JP2008154844A (ja) * | 2006-12-25 | 2008-07-10 | Gunze Ltd | 自動縫合器用縫合補強材 |
US7875058B2 (en) * | 2007-01-17 | 2011-01-25 | Arthrex, Inc. | Bunion repair using suture-button construct |
AU2008224435B2 (en) | 2007-03-15 | 2014-01-09 | Ortho-Space Ltd. | Prosthetic devices and methods for using same |
EP2550978B1 (en) | 2007-09-27 | 2014-04-30 | Ethicon, LLC | A system for cutting a retainer in a suture |
EP2280670A4 (en) * | 2008-04-28 | 2012-08-01 | Eatlittle Inc | BÉZOARD TRAINING UNITS FOR WEIGHT CONTROL |
US8814903B2 (en) | 2009-07-24 | 2014-08-26 | Depuy Mitek, Llc | Methods and devices for repairing meniscal tissue |
US8828053B2 (en) | 2009-07-24 | 2014-09-09 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
KR101143420B1 (ko) * | 2010-01-29 | 2012-05-22 | 주식회사 메타바이오메드 | 생분해성 수술용 봉합사 |
US8398678B2 (en) * | 2010-03-15 | 2013-03-19 | Arthrex, Inc. | Hallux valgus repairs using suture-button construct |
US9724080B2 (en) | 2010-04-27 | 2017-08-08 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
US9743919B2 (en) | 2010-04-27 | 2017-08-29 | DePuy Synthes Products, Inc. | Stitch lock for attaching two or more structures |
JP5763173B2 (ja) | 2010-04-27 | 2015-08-12 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 拡張可能なアンカを有するアンカアセンブリ |
US9451938B2 (en) | 2010-04-27 | 2016-09-27 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
US20130180966A1 (en) | 2010-05-04 | 2013-07-18 | Jeffrey M. Gross | Laser cutting system and methods for creating self-retaining sutures |
MX2013005072A (es) * | 2010-11-03 | 2013-12-02 | Tissuegen Inc | Hilos de sutura de autorretención eluyentes de fármacos y métodos relacionados con estos. |
US9307978B2 (en) | 2010-11-04 | 2016-04-12 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
US9307977B2 (en) | 2010-11-04 | 2016-04-12 | Conmed Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing suture to bone |
WO2012064902A2 (en) | 2010-11-09 | 2012-05-18 | Angiotech Pharmaceuticals, Inc. | Emergency self-retaining sutures and packaging |
CA2827494C (en) | 2011-02-16 | 2018-05-01 | Linvatec Corporation | Method and apparatus for securing an object to bone |
US20130172931A1 (en) | 2011-06-06 | 2013-07-04 | Jeffrey M. Gross | Methods and devices for soft palate tissue elevation procedures |
CN103006350A (zh) * | 2011-09-22 | 2013-04-03 | 苏州瑞华医院有限公司 | 一种肌腱修复网及其使用方法 |
US9289307B2 (en) | 2011-10-18 | 2016-03-22 | Ortho-Space Ltd. | Prosthetic devices and methods for using same |
US9017404B2 (en) * | 2012-01-23 | 2015-04-28 | Lloyd P. Champagne | Devices and methods for tendon repair |
EP2811929A1 (en) | 2012-02-10 | 2014-12-17 | Synthes GmbH | Suture distal locking for intramedullary nail |
TWI556785B (zh) * | 2012-03-01 | 2016-11-11 | 信迪思有限公司 | 具軟質芯材之手術用縫合線 |
US8961575B2 (en) | 2012-03-14 | 2015-02-24 | Arthrex, Inc. | CMC repair using suture-button construct |
US9585654B2 (en) | 2012-05-01 | 2017-03-07 | Dean & Webb, LLC | Segmentally rigid suture and suturing technique |
WO2014011933A1 (en) | 2012-07-12 | 2014-01-16 | Exsomed Holding Company Llc | Metacarpal bone stabilization device |
US9795426B2 (en) * | 2013-03-07 | 2017-10-24 | DePuy Synthes Products, Inc. | Implants |
WO2015050895A1 (en) | 2013-10-02 | 2015-04-09 | Exsomed Holding Company Llc | Full wrist fusion device |
WO2015081087A1 (en) * | 2013-11-26 | 2015-06-04 | The Trustees Of Columbia University In The City Of New York | Core-centered granule composed of micro-structure body |
US9622523B2 (en) | 2014-01-06 | 2017-04-18 | Exsomed International IP, LLC | Ergonomic work gloves |
US9474521B2 (en) * | 2014-03-28 | 2016-10-25 | Medos International Sàrl | Systems, devices, and methods for extruding a suture core |
CN104083188A (zh) * | 2014-06-23 | 2014-10-08 | 王明旗 | 医用肛肠科专用橡筋弹力线 |
US9775598B2 (en) * | 2014-07-20 | 2017-10-03 | New York University | Anchored suture line, device and method for surgical suturing |
AU2015343154B2 (en) * | 2014-11-04 | 2020-05-21 | Surgical Specialties Corporation | Braided suture coat |
DE102015104338A1 (de) * | 2015-03-23 | 2016-09-29 | Sitevasc Ug | Rohrförmige Hülse und System zur atraumatischen Behandlung von Hohlorganen |
US10441330B2 (en) | 2015-05-19 | 2019-10-15 | Exsomed Holding Company, Llc | Distal radius plate |
US10959761B2 (en) | 2015-09-18 | 2021-03-30 | Ortho-Space Ltd. | Intramedullary fixated subacromial spacers |
US10245091B2 (en) | 2015-12-30 | 2019-04-02 | Exsomed Holding Company, Llc | Dip fusion spike screw |
US11147604B2 (en) | 2016-01-12 | 2021-10-19 | ExsoMed Corporation | Bone stabilization device |
CN108738305A (zh) * | 2016-01-22 | 2018-11-02 | 韦恩堡金属研究产品公司 | 机织或编织管状金属结构 |
US11484401B2 (en) | 2016-02-01 | 2022-11-01 | Medos International Sarl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
US11357495B2 (en) * | 2016-02-01 | 2022-06-14 | Medos International Sarl | Tissue augmentation scaffolds for use with soft tissue fixation repair systems and methods |
AU2017227775B2 (en) * | 2016-03-01 | 2022-03-17 | Arthrex, Inc. | External bone fixation systems |
US10194923B2 (en) | 2016-05-10 | 2019-02-05 | Exsomed International IP, LLC | Tool for percutaneous joint cartilage destruction and preparation for joint fusion |
EP3478887B1 (en) | 2016-07-22 | 2022-09-07 | Us Biodesign, Llc | Process of changing cross-sectional shape within a textile |
US11045981B2 (en) | 2017-01-30 | 2021-06-29 | Ortho-Space Ltd. | Processing machine and methods for processing dip-molded articles |
AU2018203301B2 (en) | 2017-06-09 | 2024-02-08 | Medos International Sarl | Tissue augmentation tacks for use with soft tissue fixation repair systems and methods |
EP3678565A4 (en) | 2017-09-05 | 2021-10-27 | ExsoMed Corporation | THREADED NAIL FOR RADIAL CORTIC FIXATION |
US11191645B2 (en) | 2017-09-05 | 2021-12-07 | ExsoMed Corporation | Small bone tapered compression screw |
US11147681B2 (en) | 2017-09-05 | 2021-10-19 | ExsoMed Corporation | Small bone angled compression screw |
WO2019147460A1 (en) * | 2018-01-23 | 2019-08-01 | Kuraray America, Inc. | Small diameter fiber braid with central core member |
EP3890622A1 (en) | 2018-12-05 | 2021-10-13 | Medos International Sarl | Fixation members, assemblies, and related systems and methods |
KR102274565B1 (ko) * | 2019-05-09 | 2021-07-07 | 한스바이오메드 주식회사 | 봉합사 및 이를 포함하는 키트 |
AU2020203700A1 (en) | 2019-06-19 | 2021-01-14 | Medos International Sàrl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
US11272920B2 (en) | 2019-09-26 | 2022-03-15 | Medos International Sarl | One-way adjustable loop suture constructs and methods of forming and using the same |
WO2022075504A1 (ko) * | 2020-10-08 | 2022-04-14 | 한스바이오메드 주식회사 | 봉합사와 바늘 및 이들을 포함하는 키트 |
US20220192662A1 (en) | 2020-12-21 | 2022-06-23 | Ethicon, Inc. | Adaptive Sutures Dynamically Changing Wound Holding Properties Post-Implantation |
US20230030543A1 (en) | 2021-07-26 | 2023-02-02 | Medos International Sarl | Suture Having Adaptable Surface Characteristics, And Related Systems And Methods |
US20240000445A1 (en) | 2022-06-30 | 2024-01-04 | Medos International Sàrl | Multispan cinchable loops for knotless spanning of tissue between anchor points and tools for using the same |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4823753B1 (ja) | 1969-04-11 | 1973-07-16 | ||
JPS4823753U (ja) * | 1971-07-31 | 1973-03-19 | ||
US3847156A (en) | 1972-07-17 | 1974-11-12 | Sherwood Medical Ind Inc | Suture |
BE806869A (fr) | 1972-11-03 | 1974-04-30 | Ethicon Inc | Fil a ligatures tresse ameliore |
US4209859A (en) * | 1978-03-29 | 1980-07-01 | Meadox Medicals, Inc. | Ligament and tendon prosthesis of polyethylene terephthalate and method of preparing same |
US4461298A (en) | 1982-07-26 | 1984-07-24 | Ethicon, Inc. | Composite sutures of silk and hydrophobic thermoplastic elastomers |
GB8414344D0 (en) | 1984-06-05 | 1984-07-11 | Showell A W Sugicraft Ltd | Surgical element |
US4621638A (en) | 1984-07-30 | 1986-11-11 | Pfizer Hospital Products Group, Inc. | Hard elastic sutures |
US4857602A (en) * | 1986-09-05 | 1989-08-15 | American Cyanamid Company | Bioabsorbable surgical suture coating |
JPH0660471B2 (ja) * | 1986-09-18 | 1994-08-10 | 東邦レーヨン株式会社 | 複合線条体 |
JPH01138447A (ja) | 1987-11-25 | 1989-05-31 | Nec Corp | 異物検出方法 |
EP0328401A1 (en) * | 1988-02-11 | 1989-08-16 | Unisearch Limited | Anastomosis augmentation device |
JPH0431072Y2 (ja) | 1988-03-14 | 1992-07-27 | ||
US4990158A (en) * | 1989-05-10 | 1991-02-05 | United States Surgical Corporation | Synthetic semiabsorbable tubular prosthesis |
US5147400A (en) | 1989-05-10 | 1992-09-15 | United States Surgical Corporation | Connective tissue prosthesis |
US5217495A (en) | 1989-05-10 | 1993-06-08 | United States Surgical Corporation | Synthetic semiabsorbable composite yarn |
US5133738A (en) | 1989-09-27 | 1992-07-28 | United States Surgical Corporation | Combined surgical needle-spiroid braided suture device |
US4959069A (en) | 1989-10-20 | 1990-09-25 | Ethicon, Inc. | Braided surgical sutures |
US5102420A (en) | 1990-11-14 | 1992-04-07 | Ethicon, Inc. | Suture coated with a polyetheramide |
US5234006A (en) | 1991-01-18 | 1993-08-10 | Eaton Alexander M | Adjustable sutures and method of using the same |
US5314446A (en) | 1992-02-19 | 1994-05-24 | Ethicon, Inc. | Sterilized heterogeneous braids |
US6251137B1 (en) | 1994-03-23 | 2001-06-26 | Mcghan Medical Corporation | Synthetic triglyceride filler material for surgically implanted prostheses |
US6174333B1 (en) * | 1994-06-06 | 2001-01-16 | Osiris Therapeutics, Inc. | Biomatrix for soft tissue regeneration using mesenchymal stem cells |
US5464424A (en) | 1994-06-27 | 1995-11-07 | O'donnell, Jr.; Francis E. | Laser adjustable suture |
AU3147795A (en) | 1994-07-26 | 1996-02-22 | University Of Akron, The | Device and method for restoration of connective tissue |
US5562736A (en) * | 1994-10-17 | 1996-10-08 | Raymedica, Inc. | Method for surgical implantation of a prosthetic spinal disc nucleus |
US5651377A (en) | 1995-05-22 | 1997-07-29 | O'donnell, Jr.; Francis E. | Laser adjustable suture |
US5810851A (en) | 1996-03-05 | 1998-09-22 | Yoon; Inbae | Suture spring device |
TW528600B (en) * | 1996-11-20 | 2003-04-21 | Yasuhiko Shimizu | Artificial neural canal |
JP3712849B2 (ja) * | 1996-12-10 | 2005-11-02 | 三井化学株式会社 | 分解性モノフィラメント及びその製造方法 |
US6022376A (en) * | 1997-06-06 | 2000-02-08 | Raymedica, Inc. | Percutaneous prosthetic spinal disc nucleus and method of manufacture |
US6165217A (en) | 1997-10-02 | 2000-12-26 | Gore Enterprise Holdings, Inc. | Self-cohering, continuous filament non-woven webs |
US6605294B2 (en) * | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
US5952232A (en) | 1998-09-17 | 1999-09-14 | Rothman; James Edward | Expandible microparticle intracellular delivery system |
JP2000125855A (ja) | 1998-10-21 | 2000-05-09 | Gunze Ltd | 人工皮膚 |
US6045571A (en) | 1999-04-14 | 2000-04-04 | Ethicon, Inc. | Multifilament surgical cord |
US7033603B2 (en) * | 1999-08-06 | 2006-04-25 | Board Of Regents The University Of Texas | Drug releasing biodegradable fiber for delivery of therapeutics |
US6197043B1 (en) | 1999-08-18 | 2001-03-06 | James A. Davidson | Isoelastic suture material and device |
US6296659B1 (en) | 2000-02-29 | 2001-10-02 | Opus Medical, Inc. | Single-tailed suturing method and apparatus |
WO2001091822A1 (en) | 2000-05-31 | 2001-12-06 | Mnemoscience Gmbh | Shape memory thermoplastics and polymer networks for tissue engineering |
US6527795B1 (en) * | 2000-10-18 | 2003-03-04 | Ethicon, Inc. | Knotless suture anchor system and method of use |
US8083768B2 (en) | 2000-12-14 | 2011-12-27 | Ensure Medical, Inc. | Vascular plug having composite construction |
JP4740482B2 (ja) | 2001-07-09 | 2011-08-03 | グンゼ株式会社 | 神経再生チューブ |
JP4406283B2 (ja) * | 2001-07-30 | 2010-01-27 | 光夫 越智 | 組織再生用基材、移植用材料及びその製法 |
AU2003213844B2 (en) | 2002-03-11 | 2008-10-02 | Dow Global Technologies Inc. | Reversible, heat-set, elastic fibers, and method of making and articles made from same |
JP4344112B2 (ja) | 2002-03-19 | 2009-10-14 | 泰彦 田畑 | 生体組織様構造体、骨髄幹細胞の培養方法および培養用キット |
US7070610B2 (en) | 2002-03-30 | 2006-07-04 | Samyang Corporation | Monofilament suture and manufacturing method thereof |
US7175632B2 (en) | 2002-05-15 | 2007-02-13 | Linvatec Corporation | Cross-pin graft fixation instruments and method |
US7338492B2 (en) | 2002-05-15 | 2008-03-04 | Linvatec Corporation | Cross-pin graft fixation, instruments, and methods |
US7678138B2 (en) | 2002-05-15 | 2010-03-16 | Linvatec Corporation | Two piece cross-pin graft fixation |
US7270666B2 (en) | 2002-05-15 | 2007-09-18 | Linvatec Corporation | Cross-pin graft fixation, instruments, and methods |
ITGE20030007A1 (it) | 2003-01-27 | 2004-07-28 | Sergio Capurro | Filo elastico rivestito per chirurgia |
US20040267313A1 (en) | 2003-06-27 | 2004-12-30 | Linvatec Corporation | High strength multi-component surgical cord |
US20050247320A1 (en) | 2003-10-10 | 2005-11-10 | Stack Richard S | Devices and methods for retaining a gastro-esophageal implant |
US8206456B2 (en) | 2003-10-10 | 2012-06-26 | Barosense, Inc. | Restrictive and/or obstructive implant system for inducing weight loss |
US8257393B2 (en) | 2003-12-04 | 2012-09-04 | Ethicon, Inc. | Active suture for the delivery of therapeutic fluids |
CA2546611A1 (en) | 2003-12-04 | 2005-06-23 | Ethicon, Inc. | Active suture for the delivery of therapeutic fluids |
US7329271B2 (en) | 2003-12-18 | 2008-02-12 | Ethicon, Inc. | High strength suture with absorbable core |
US20060025818A1 (en) | 2004-07-29 | 2006-02-02 | Ferguson Patrick J | Strong, flexible suture material |
US8585772B2 (en) | 2005-04-26 | 2013-11-19 | Poly-Med, Inc. | Absorbable/biodegradable composite yarns and property-modulated surgical implants therefrom |
US8709023B2 (en) | 2007-07-17 | 2014-04-29 | Poly-Med, Inc. | Absorbable / biodegradable composite yarn constructs and applications thereof |
MX2007013633A (es) * | 2005-05-04 | 2008-03-13 | Etech Ag | Elemento de union rigido, de contraccion lenta, para medicina y otros usos. |
US7674271B2 (en) | 2005-05-04 | 2010-03-09 | InTailor Surgical, Inc. | Endoluminal gastric ring and method |
US20060253126A1 (en) | 2005-05-04 | 2006-11-09 | Bernard Medical, Llc | Endoluminal suturing device and method |
US20060253127A1 (en) | 2005-05-04 | 2006-11-09 | Bernard Medical, Llc | Endoluminal linear suturing device |
US8663277B2 (en) | 2005-06-29 | 2014-03-04 | Ethicon, Inc. | Braided barbed suture |
US20070118151A1 (en) | 2005-11-21 | 2007-05-24 | The Brigham And Women's Hospital, Inc. | Percutaneous cardiac valve repair with adjustable artificial chordae |
ATE498027T1 (de) | 2005-12-07 | 2011-02-15 | Univ Ramot | Wirkstoffabgebende verbundkörper |
US20090035572A1 (en) | 2006-04-06 | 2009-02-05 | Tyco Healthcare Group Lp | Yarns containing thermoplastic elastomer copolymer and polyolefin filaments |
AU2007201213A1 (en) | 2006-04-06 | 2007-10-25 | Tyco Healthcare Group Lp | Yarns containing thermoplastic elastomer copolymer and polyolefin filaments |
JP4118928B2 (ja) | 2006-07-12 | 2008-07-16 | 有限会社末富エンジニアリング | 伸縮性複合繊維 |
AU2007303137B2 (en) | 2006-10-03 | 2014-04-10 | Sinclair Pharmaceuticals Limited | Minimally invasive tissue support |
US8758407B2 (en) | 2006-12-21 | 2014-06-24 | Warsaw Orthopedic, Inc. | Methods for positioning a load-bearing orthopedic implant device in vivo |
EP2106250B1 (en) | 2007-01-25 | 2020-04-01 | Boston Scientific Limited | Endoscope with preloaded or preloadable stent |
US7469526B2 (en) | 2007-02-21 | 2008-12-30 | Gilbert Patrick | Heat/fire resistant sewing thread and method for producing same |
DK2207529T3 (en) | 2007-09-07 | 2015-03-09 | Mati Therapeutics Inc | PHARMACEUTICAL cores for the sustained release of therapeutic agents |
US8118834B1 (en) | 2007-12-20 | 2012-02-21 | Angiotech Pharmaceuticals, Inc. | Composite self-retaining sutures and method |
US7762287B2 (en) | 2008-01-25 | 2010-07-27 | Invista North America S.A.R.L. | Stretch wovens with separated elastic yarn system |
GB2458878A (en) | 2008-03-04 | 2009-10-07 | Xiros Plc | An implantable prosthetic cord |
DE102008057216A1 (de) | 2008-11-06 | 2010-05-12 | Aesculap Ag | Chirurgischer Faden mit Kern-Mantel-Aufbau |
CN201543004U (zh) | 2009-06-30 | 2010-08-11 | 中国人民解放军第二军医大学 | 用于外科缝线、疝和体壁修复网片、防粘连膜片的纤维 |
TWI556785B (zh) | 2012-03-01 | 2016-11-11 | 信迪思有限公司 | 具軟質芯材之手術用縫合線 |
CN104155479B (zh) | 2014-07-15 | 2016-08-17 | 大连理工大学 | 模块式扫描探针显微镜用探针架 |
-
2006
- 2006-05-04 MX MX2007013633A patent/MX2007013633A/es active IP Right Grant
- 2006-05-04 US US11/913,656 patent/US8870915B2/en active Active
- 2006-05-04 AU AU2006243216A patent/AU2006243216B2/en active Active
- 2006-05-04 AT AT06755020T patent/ATE523214T1/de active
- 2006-05-04 EP EP06755020A patent/EP1973582B1/de active Active
- 2006-05-04 WO PCT/EP2006/062061 patent/WO2006117398A2/de active Application Filing
- 2006-05-04 BR BRPI0612350A patent/BRPI0612350B8/pt active IP Right Grant
- 2006-05-04 KR KR1020127029481A patent/KR101387070B1/ko active IP Right Grant
- 2006-05-04 RU RU2007144061/15A patent/RU2404821C2/ru not_active IP Right Cessation
- 2006-05-04 KR KR1020077025654A patent/KR101354527B1/ko active IP Right Grant
- 2006-05-04 CN CN2006800152690A patent/CN101193665B/zh active Active
- 2006-05-04 JP JP2008509452A patent/JP5204647B2/ja active Active
- 2006-05-04 CA CA2608107A patent/CA2608107C/en active Active
-
2007
- 2007-10-10 IL IL186571A patent/IL186571A/en active IP Right Grant
- 2007-10-19 NO NO20075359A patent/NO20075359L/no not_active Application Discontinuation
- 2007-11-15 ZA ZA200709837A patent/ZA200709837B/xx unknown
-
2012
- 2012-12-12 JP JP2012271669A patent/JP6113485B2/ja active Active
-
2013
- 2013-03-13 US US13/800,640 patent/US9757120B2/en active Active
- 2013-03-13 US US13/800,889 patent/US9757121B2/en active Active
-
2015
- 2015-06-24 JP JP2015126366A patent/JP6023277B2/ja active Active
-
2016
- 2016-12-28 JP JP2016255502A patent/JP6422934B2/ja active Active
-
2017
- 2017-08-28 US US15/687,784 patent/US10542972B2/en active Active
- 2017-12-25 JP JP2017247503A patent/JP6513782B2/ja active Active
-
2019
- 2019-12-23 US US16/724,426 patent/US11471154B2/en active Active
-
2022
- 2022-09-14 US US17/932,038 patent/US20230144510A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6513782B2 (ja) | 結合部材 | |
US9888996B2 (en) | In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers | |
CN117979909A (zh) | 具有适应性表面特性的缝合线以及相关系统和方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20181016 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20190116 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190128 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190319 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190410 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6513782 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |