JP6463732B2 - 上昇したレベルの外因性シャペロンを有する細胞抽出物を用いる細菌無細胞合成系における生物活性のあるタンパク質の発現 - Google Patents

上昇したレベルの外因性シャペロンを有する細胞抽出物を用いる細菌無細胞合成系における生物活性のあるタンパク質の発現 Download PDF

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JP6463732B2
JP6463732B2 JP2016509127A JP2016509127A JP6463732B2 JP 6463732 B2 JP6463732 B2 JP 6463732B2 JP 2016509127 A JP2016509127 A JP 2016509127A JP 2016509127 A JP2016509127 A JP 2016509127A JP 6463732 B2 JP6463732 B2 JP 6463732B2
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protein
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JP2016518833A (ja
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アリス ヤム，
アリス ヤム，
ダン グロフ，
ダン グロフ，
パトリック リバーズ，
パトリック リバーズ，
クリストファー ディー． サノス，
クリストファー ディー． サノス，
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ストロ バイオファーマ， インコーポレイテッド
ストロ バイオファーマ， インコーポレイテッド
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2016509127A 2013-04-19 2014-04-18 上昇したレベルの外因性シャペロンを有する細胞抽出物を用いる細菌無細胞合成系における生物活性のあるタンパク質の発現 Active JP6463732B2 (ja)

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US201361813914P 2013-04-19 2013-04-19
US61/813,914 2013-04-19
US201461937069P 2014-02-07 2014-02-07
US61/937,069 2014-02-07
PCT/US2014/034643 WO2014172631A2 (en) 2013-04-19 2014-04-18 Expression of biologically active proteins in a bacterial cell-free synthesis system using bacterial cells transformed to exhibit elevated levels of chaperone expression

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JP2018136909A Withdrawn JP2018157837A (ja) 2013-04-19 2018-07-20 上昇したレベルの外因性シャペロンを有する細胞抽出物を用いる細菌無細胞合成系における生物活性のあるタンパク質の発現

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CN (1) CN105283556B (enExample)
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ES2922358T3 (es) 2022-09-13
EP2986731A2 (en) 2016-02-24
SG10202108497TA (en) 2021-09-29
IL242148B (en) 2019-03-31
AU2014253785B2 (en) 2018-07-19
HK1220993A1 (en) 2017-05-19
US20210054429A1 (en) 2021-02-25
CN105283556A (zh) 2016-01-27
DK2986731T3 (da) 2022-08-01
JP2016518833A (ja) 2016-06-30
US20190161781A1 (en) 2019-05-30
US20140315245A1 (en) 2014-10-23
US10190145B2 (en) 2019-01-29
KR20160002913A (ko) 2016-01-08
CA2909516C (en) 2023-03-07
JP2018157837A (ja) 2018-10-11
WO2014172631A4 (en) 2015-02-19
SG11201508642WA (en) 2015-11-27
HUE059565T2 (hu) 2022-11-28
WO2014172631A2 (en) 2014-10-23
WO2014172631A3 (en) 2014-12-18
CN105283556B (zh) 2020-07-14
CA2909516A1 (en) 2014-10-23
EP2986731B1 (en) 2022-05-18
KR102289258B1 (ko) 2021-08-11
AU2014253785A1 (en) 2015-11-05
US10774354B2 (en) 2020-09-15

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