JP6397479B2 - ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート - Google Patents

ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート Download PDF

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JP6397479B2
JP6397479B2 JP2016503199A JP2016503199A JP6397479B2 JP 6397479 B2 JP6397479 B2 JP 6397479B2 JP 2016503199 A JP2016503199 A JP 2016503199A JP 2016503199 A JP2016503199 A JP 2016503199A JP 6397479 B2 JP6397479 B2 JP 6397479B2
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hrs
seq
polypeptide
region
fusion polypeptide
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JP2016519569A5 (https=
JP2016519569A (ja
Inventor
イン ビュークラー，
イン ビュークラー，
カイル チャン，
カイル チャン，
ミン−ハ ド，
ミン−ハ ド，
ダリン リー，
ダリン リー，
クリスティ ピール，
クリスティ ピール，
マーク トーマス，
マーク トーマス，
ジェフリー ディー． ワトキンス，
ジェフリー ディー． ワトキンス，
チ−ファン ウー，
チ−ファン ウー，
ジョン ディー． メンドレイン，
ジョン ディー． メンドレイン，
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エータイアー ファーマ， インコーポレイテッド
エータイアー ファーマ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y601/00—Ligases forming carbon-oxygen bonds (6.1)
    • C12Y601/01—Ligases forming aminoacyl-tRNA and related compounds (6.1.1)
    • C12Y601/01021—Histidine-tRNA ligase (6.1.1.21)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Connection Of Motors, Electrical Generators, Mechanical Devices, And The Like (AREA)
JP2016503199A 2013-03-15 2014-03-14 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート Active JP6397479B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361789011P 2013-03-15 2013-03-15
US61/789,011 2013-03-15
PCT/US2014/029699 WO2014145050A1 (en) 2013-03-15 2014-03-14 Histidyl-trna synthetase-fc conjugates

Related Child Applications (1)

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JP2018163396A Division JP6687692B2 (ja) 2013-03-15 2018-08-31 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート

Publications (3)

Publication Number Publication Date
JP2016519569A JP2016519569A (ja) 2016-07-07
JP2016519569A5 JP2016519569A5 (https=) 2017-03-23
JP6397479B2 true JP6397479B2 (ja) 2018-09-26

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Family Applications (5)

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JP2016503199A Active JP6397479B2 (ja) 2013-03-15 2014-03-14 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2018163396A Active JP6687692B2 (ja) 2013-03-15 2018-08-31 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2020066585A Withdrawn JP2020141673A (ja) 2013-03-15 2020-04-02 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2022062451A Pending JP2022104983A (ja) 2013-03-15 2022-04-04 ヒスチジル－ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2024175280A Pending JP2025004141A (ja) 2013-03-15 2024-10-04 ヒスチジル－ｔＲＮＡシンテターゼＦｃコンジュゲート

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JP2018163396A Active JP6687692B2 (ja) 2013-03-15 2018-08-31 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2020066585A Withdrawn JP2020141673A (ja) 2013-03-15 2020-04-02 ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2022062451A Pending JP2022104983A (ja) 2013-03-15 2022-04-04 ヒスチジル－ｔＲＮＡシンテターゼＦｃコンジュゲート
JP2024175280A Pending JP2025004141A (ja) 2013-03-15 2024-10-04 ヒスチジル－ｔＲＮＡシンテターゼＦｃコンジュゲート

Country Status (9)

Country Link
US (6) US9587235B2 (https=)
EP (2) EP3460054B1 (https=)
JP (5) JP6397479B2 (https=)
CN (2) CN105378075B (https=)
AU (1) AU2014233436B2 (https=)
CA (1) CA2907046C (https=)
DK (2) DK3460054T3 (https=)
ES (2) ES2708565T3 (https=)
WO (1) WO2014145050A1 (https=)

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