JP6095367B2 - 癌治療のための診断方法および組成物 - Google Patents

癌治療のための診断方法および組成物 Download PDF

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JP6095367B2
JP6095367B2 JP2012520702A JP2012520702A JP6095367B2 JP 6095367 B2 JP6095367 B2 JP 6095367B2 JP 2012520702 A JP2012520702 A JP 2012520702A JP 2012520702 A JP2012520702 A JP 2012520702A JP 6095367 B2 JP6095367 B2 JP 6095367B2
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patient
vegf
expression level
antagonist
treatment
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JP2012532628A5 (enExample
JP2012532628A (ja
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マイク シュミット，
マイク シュミット，
ローラ サンダース，
ローラ サンダース，
ラジーブ ラジャ，
ラジーブ ラジャ，
ラジェシュ， ディー． パテル，
ラジェシュ， ディー． パテル，
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Genentech Inc
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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JP2012520702A 2009-07-13 2010-07-12 癌治療のための診断方法および組成物 Expired - Fee Related JP6095367B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22512009P 2009-07-13 2009-07-13
US61/225,120 2009-07-13
US35173310P 2010-06-04 2010-06-04
US61/351,733 2010-06-04
PCT/US2010/041706 WO2011008696A2 (en) 2009-07-13 2010-07-12 Diagnostic methods and compositions for treatment of cancer

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JP2016255038A Division JP2017099389A (ja) 2009-07-13 2016-12-28 癌治療のための診断方法および組成物

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JP2012532628A JP2012532628A (ja) 2012-12-20
JP2012532628A5 JP2012532628A5 (enExample) 2013-08-22
JP6095367B2 true JP6095367B2 (ja) 2017-03-15

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US (2) US20110076271A1 (enExample)
EP (1) EP2454380A2 (enExample)
JP (2) JP6095367B2 (enExample)
KR (1) KR20120106935A (enExample)
CN (2) CN102482715A (enExample)
AU (1) AU2010273585B2 (enExample)
BR (1) BR112012000735A2 (enExample)
CA (1) CA2766403A1 (enExample)
HK (1) HK1226108A1 (enExample)
IL (1) IL216926A0 (enExample)
MX (1) MX2012000620A (enExample)
SG (2) SG177640A1 (enExample)
WO (1) WO2011008696A2 (enExample)

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CN109154027A (zh) * 2016-04-15 2019-01-04 豪夫迈·罗氏有限公司 用于监测和治疗癌症的方法
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SG11201810775SA (en) * 2016-06-03 2019-01-30 Samsung Life Public Welfare Foundation Anti-nrp1 antibody screening method
CN106282376A (zh) * 2016-09-27 2017-01-04 上海交通大学医学院附属第九人民医院 一种用于检测bmp9基因表达的反义rna探针
JP2020503872A (ja) * 2017-01-09 2020-02-06 セカルナ・ファーマシューティカルズ・ゲーエムベーハー・ウント・コ・カーゲー Ｎｒｐ１の発現を阻害するオリゴヌクレオチド
CN110546277B (zh) 2017-03-01 2024-06-11 豪夫迈·罗氏有限公司 用于癌症的诊断和治疗方法
CN109828111A (zh) * 2017-11-23 2019-05-31 复旦大学附属肿瘤医院 MFAP5在制备筛选α干扰素干预肝癌敏感人群标志物的制剂中的用途
CN109828114A (zh) * 2017-11-23 2019-05-31 复旦大学附属肿瘤医院 MFAP5蛋白作为筛选α干扰素治疗肝癌敏感人群的试剂盒中的方法及应用
EP3837550A1 (en) * 2018-08-17 2021-06-23 Roche Diagnostics GmbH Circulating bmp10 (bone morphogenic protein 10) in the assessment of atrial fibrillation
CN110893238A (zh) * 2018-09-13 2020-03-20 常州大学 抑制血管内皮生长因子活性和表达量的物质在制备抑制淋巴结转移的产品中的应用
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US20140099326A1 (en) 2014-04-10
BR112012000735A2 (pt) 2016-11-16
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MX2012000620A (es) 2012-01-27
EP2454380A2 (en) 2012-05-23
KR20120106935A (ko) 2012-09-27
US20110076271A1 (en) 2011-03-31
JP2012532628A (ja) 2012-12-20
WO2011008696A3 (en) 2011-04-14
CN106148547A (zh) 2016-11-23
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AU2010273585B2 (en) 2015-04-23
CN102482715A (zh) 2012-05-30
SG177640A1 (en) 2012-02-28
US20140302056A2 (en) 2014-10-09
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