JP5996630B2 - コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用 - Google Patents

コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用 Download PDF

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JP5996630B2
JP5996630B2 JP2014504007A JP2014504007A JP5996630B2 JP 5996630 B2 JP5996630 B2 JP 5996630B2 JP 2014504007 A JP2014504007 A JP 2014504007A JP 2014504007 A JP2014504007 A JP 2014504007A JP 5996630 B2 JP5996630 B2 JP 5996630B2
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seq
dna
compact talen
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activity
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JP2014511698A5 (enExample
JP2014511698A (ja
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デュシャトー，フィリップ
ジュイルラト，アレクサンドル
ヴァルトン，ジュリアン
ベルトナティ，クラウディア
エピナト，ジャン−シャルル
シルヴァ，ジョージ，エイチ．
ブールドレー，マリーン
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Cellectis SA
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/07—Fusion polypeptide containing a localisation/targetting motif containing a mitochondrial localisation signal
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

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  • Gastroenterology & Hepatology (AREA)
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  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014504007A 2011-04-05 2012-04-05 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用 Active JP5996630B2 (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201161472065P 2011-04-05 2011-04-05
US61/472,065 2011-04-05
US201161496454P 2011-06-13 2011-06-13
US61/496,454 2011-06-13
US201161499043P 2011-06-20 2011-06-20
US201161499047P 2011-06-20 2011-06-20
US61/499,047 2011-06-20
US61/499,043 2011-06-20
US201161533123P 2011-09-09 2011-09-09
US201161533098P 2011-09-09 2011-09-09
US61/533,123 2011-09-09
US61/533,098 2011-09-09
US201161579544P 2011-12-22 2011-12-22
US61/579,544 2011-12-22
PCT/US2012/032426 WO2012138927A2 (en) 2011-04-05 2012-04-05 Method for the generation of compact tale-nucleases and uses thereof

Related Child Applications (1)

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JP2016163762A Division JP6695239B2 (ja) 2011-04-05 2016-08-24 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用

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JP2014511698A JP2014511698A (ja) 2014-05-19
JP2014511698A5 JP2014511698A5 (enExample) 2015-03-12
JP5996630B2 true JP5996630B2 (ja) 2016-09-21

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JP2014504007A Active JP5996630B2 (ja) 2011-04-05 2012-04-05 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用
JP2016163762A Active JP6695239B2 (ja) 2011-04-05 2016-08-24 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用
JP2018184887A Active JP6839691B2 (ja) 2011-04-05 2018-09-28 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用

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JP2016163762A Active JP6695239B2 (ja) 2011-04-05 2016-08-24 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用
JP2018184887A Active JP6839691B2 (ja) 2011-04-05 2018-09-28 コンパクトｔａｌｅ−ヌクレアーゼを作製する方法及びその使用

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US (5) US20140115726A1 (enExample)
EP (3) EP2694089B1 (enExample)
JP (3) JP5996630B2 (enExample)
KR (1) KR101982360B1 (enExample)
CN (1) CN103608027B (enExample)
AU (2) AU2012240110B2 (enExample)
CA (2) CA2832534C (enExample)
DK (1) DK2694091T3 (enExample)
ES (1) ES2728436T3 (enExample)
HK (1) HK1253952A1 (enExample)
IL (1) IL228747B (enExample)
SG (2) SG10201602651YA (enExample)
WO (2) WO2012138927A2 (enExample)

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