MX2021011726A - Escindasas modificadas, usos de las mismas y kits relacionados. - Google Patents

Escindasas modificadas, usos de las mismas y kits relacionados.

Info

Publication number
MX2021011726A
MX2021011726A MX2021011726A MX2021011726A MX2021011726A MX 2021011726 A MX2021011726 A MX 2021011726A MX 2021011726 A MX2021011726 A MX 2021011726A MX 2021011726 A MX2021011726 A MX 2021011726A MX 2021011726 A MX2021011726 A MX 2021011726A
Authority
MX
Mexico
Prior art keywords
modified
cleavases
kits
related kits
methods
Prior art date
Application number
MX2021011726A
Other languages
English (en)
Inventor
Lei Shi
Robert C James
Kevin Desai
Gunderson Kevin L
Iii Stephen Verespy
Original Assignee
Encodia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encodia Inc filed Critical Encodia Inc
Publication of MX2021011726A publication Critical patent/MX2021011726A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14004—Dipeptidyl-peptidase III (3.4.14.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

En el presente documento se proporcionan escindasas modificadas para eliminar aminoácidos de péptidos, polipéptidos y proteínas. También se proporcionan métodos para usar las escindasas modificadas para tratar polipéptidos y kits que comprenden la escindasa modificada. En algunas modalidades, los métodos y los kits también incluyen otros componentes para la secuenciación y/o análisis de macromoléculas.
MX2021011726A 2019-03-26 2020-03-24 Escindasas modificadas, usos de las mismas y kits relacionados. MX2021011726A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962824157P 2019-03-26 2019-03-26
US201962823927P 2019-03-26 2019-03-26
US201962931737P 2019-11-06 2019-11-06
PCT/US2020/024521 WO2020198264A1 (en) 2019-03-26 2020-03-24 Modified cleavases, uses thereof and related kits

Publications (1)

Publication Number Publication Date
MX2021011726A true MX2021011726A (es) 2021-10-22

Family

ID=72612078

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021011726A MX2021011726A (es) 2019-03-26 2020-03-24 Escindasas modificadas, usos de las mismas y kits relacionados.

Country Status (9)

Country Link
EP (1) EP3947667A4 (es)
JP (1) JP2022526939A (es)
KR (1) KR102567902B1 (es)
CN (1) CN113993997A (es)
AU (1) AU2020247918B2 (es)
CA (1) CA3134776A1 (es)
MX (1) MX2021011726A (es)
SG (1) SG11202110373WA (es)
WO (1) WO2020198264A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11427814B2 (en) 2019-03-26 2022-08-30 Encodia, Inc. Modified cleavases, uses thereof and related kits
US20240011009A1 (en) * 2020-03-24 2024-01-11 Encodia, Inc. Modified dipeptide cleavases, uses thereof and related kits
WO2022147334A1 (en) * 2020-12-31 2022-07-07 Encodia, Inc. Metalloenzymes for biomolecular recognition of n-terminal modified peptides
WO2023013640A1 (ja) * 2021-08-02 2023-02-09 Ｓｐｉｂｅｒ株式会社 多孔質体及びその製造方法
CN114460052B (zh) * 2022-01-11 2023-06-20 武汉理工大学 一种基于荧光碳量子点直接检测丙酮酸钠浓度的方法
CN116426509B (zh) * 2023-04-27 2024-07-30 湖北佶凯星生物科技有限公司 一种碱性蛋白酶组合突变体及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW257792B (es) * 1992-10-01 1995-09-21 Lilly Co Eli
US6875851B1 (en) * 1999-03-05 2005-04-05 University Of Georgia Research Foundation, Inc. Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis
HUP0301356A3 (en) * 2000-10-12 2010-03-29 Ferring Bv Novel serine protease genes related to dppiv
JP2006516889A (ja) * 2002-10-10 2006-07-13 ダイヴァーサ コーポレイション プロテアーゼ、それをコードする核酸並びにその製造および使用方法
WO2005015239A2 (en) * 2003-08-07 2005-02-17 Cornell Research Foundation, Inc. Method for n-terminal labeling of proteins
EP1972349A1 (en) * 2007-03-21 2008-09-24 Biocompatibles UK Limited GLP-1 fusion peptides conjugated to polymer(s), their production and use
EP1975176A1 (en) * 2007-03-27 2008-10-01 Biocompatibles UK Limited Novel glp-1 fusion peptides, their production and use
EP2034020A1 (en) * 2007-08-30 2009-03-11 Procomcure Biotech GmbH Method for manufacturing a modified peptide
WO2010065322A1 (en) * 2008-12-01 2010-06-10 Research Triangle Institute Concurrent identification of multitudes of polypeptides
KR101982360B1 (ko) * 2011-04-05 2019-05-24 셀렉티스 콤팩트 tale-뉴클레아제의 발생 방법 및 이의 용도
WO2013110766A1 (en) * 2012-01-26 2013-08-01 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
US9435810B2 (en) * 2013-03-15 2016-09-06 Washington University Molecules and methods for iterative polypeptide analysis and processing
CN110199019B (zh) 2016-05-02 2024-09-10 Encodia有限公司 采用核酸编码的大分子分析

Also Published As

Publication number Publication date
EP3947667A1 (en) 2022-02-09
JP2022526939A (ja) 2022-05-27
WO2020198264A1 (en) 2020-10-01
AU2020247918B2 (en) 2022-06-30
WO2020198264A8 (en) 2021-01-07
KR20210143236A (ko) 2021-11-26
AU2020247918A1 (en) 2021-10-21
KR102567902B1 (ko) 2023-08-18
CA3134776A1 (en) 2020-10-01
EP3947667A4 (en) 2022-12-28
SG11202110373WA (en) 2021-10-28
CN113993997A (zh) 2022-01-28

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