JP5825672B2 - 高純度セラミド類の製造方法 - Google Patents

高純度セラミド類の製造方法 Download PDF

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JP5825672B2
JP5825672B2 JP2011281654A JP2011281654A JP5825672B2 JP 5825672 B2 JP5825672 B2 JP 5825672B2 JP 2011281654 A JP2011281654 A JP 2011281654A JP 2011281654 A JP2011281654 A JP 2011281654A JP 5825672 B2 JP5825672 B2 JP 5825672B2
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Prior art keywords
carbon atoms
ceramide
group
purity
alkyl group
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JP2011281654A
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Japanese (ja)
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JP2013129640A (ja
Inventor
賢哉 石田
賢哉 石田
健司 八木
健司 八木
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Takasago International Corp
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Takasago International Corp
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Priority to JP2011281654A priority Critical patent/JP5825672B2/ja
Priority to CN201280059943.0A priority patent/CN103974930B/zh
Priority to IN1086MUN2014 priority patent/IN2014MN01086A/en
Priority to PCT/JP2012/007122 priority patent/WO2013094108A1/ja
Priority to EP12859986.7A priority patent/EP2796444B1/en
Priority to US14/366,883 priority patent/US9079826B2/en
Publication of JP2013129640A publication Critical patent/JP2013129640A/ja
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Publication of JP5825672B2 publication Critical patent/JP5825672B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
JP2011281654A 2011-12-22 2011-12-22 高純度セラミド類の製造方法 Active JP5825672B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2011281654A JP5825672B2 (ja) 2011-12-22 2011-12-22 高純度セラミド類の製造方法
CN201280059943.0A CN103974930B (zh) 2011-12-22 2012-11-07 高纯度神经酰胺类的制造方法
IN1086MUN2014 IN2014MN01086A (https=) 2011-12-22 2012-11-07
PCT/JP2012/007122 WO2013094108A1 (ja) 2011-12-22 2012-11-07 高純度セラミド類の製造方法
EP12859986.7A EP2796444B1 (en) 2011-12-22 2012-11-07 Method for producing high-purity ceramide
US14/366,883 US9079826B2 (en) 2011-12-22 2012-11-07 Method for producing high-purity ceramide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011281654A JP5825672B2 (ja) 2011-12-22 2011-12-22 高純度セラミド類の製造方法

Publications (2)

Publication Number Publication Date
JP2013129640A JP2013129640A (ja) 2013-07-04
JP5825672B2 true JP5825672B2 (ja) 2015-12-02

Family

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Family Applications (1)

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JP2011281654A Active JP5825672B2 (ja) 2011-12-22 2011-12-22 高純度セラミド類の製造方法

Country Status (6)

Country Link
US (1) US9079826B2 (https=)
EP (1) EP2796444B1 (https=)
JP (1) JP5825672B2 (https=)
CN (1) CN103974930B (https=)
IN (1) IN2014MN01086A (https=)
WO (1) WO2013094108A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6232008B2 (ja) 2015-03-19 2017-11-15 国立大学法人北海道大学 酸化抑制剤及びこれを用いた油脂含有飲食品
CN112759535B (zh) * 2019-11-01 2024-04-05 广东东阳光药业股份有限公司 一种pf-06651600中间体的制备方法
CN119013246A (zh) 2022-02-21 2024-11-22 柯泰亚生物科技(上海)有限公司 鞘脂生产
WO2024189590A1 (en) * 2023-03-16 2024-09-19 Cataya Bio (Shanghai) Co. Production of ceramides
CN121219259A (zh) 2023-05-29 2025-12-26 柯泰亚生物科技(上海)有限公司 脂质共混物
CN117567310A (zh) * 2023-11-28 2024-02-20 重庆智合生物医药有限公司 一种神经酰胺np1的合成方法
CN117567311A (zh) * 2023-11-28 2024-02-20 重庆智合生物医药有限公司 一种高效制备α-羟基脂肪酸神经酰胺的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0692349B2 (ja) 1986-03-06 1994-11-16 和光純薬工業株式会社 光学活性不飽和アミノアルコール誘導体の新規な製法
AU2135095A (en) 1994-03-18 1995-10-09 Gist-Brocades B.V. Linoleoylamide based ceramide derivative and its use in cosmetic preparations for the treatment of dry skin
EP0688871A3 (en) 1994-06-24 1998-07-08 Quest International B.V. Preparation of phytosphingosine derivative
FR2732680B1 (fr) 1995-04-05 1997-05-09 Oreal Composes de type ceramides, leur procede de preparation et leur utilisation
JP4101320B2 (ja) * 1996-10-11 2008-06-18 高砂香料工業株式会社 一級アミド誘導体の製造方法
JP3148136B2 (ja) 1996-12-26 2001-03-19 高砂香料工業株式会社 新規なキラルジホスフィン化合物、その製造中間体、該ジホス フィン化合物を配位子とする遷移金属錯体並びに該錯体を含む 不斉水素化触媒
JP3485232B2 (ja) 1997-01-31 2004-01-13 高砂香料工業株式会社 光学活性化合物及びその製造方法
JP3549390B2 (ja) 1998-03-23 2004-08-04 高砂香料工業株式会社 ルテニウム−ホスフィン錯体及びその製造方法
JP5274256B2 (ja) 2006-09-26 2013-08-28 株式会社カネカ 光学活性β−ヒドロキシ−α−アミノカルボン酸エステルの製造方法

Also Published As

Publication number Publication date
EP2796444A4 (en) 2015-12-16
US20140364649A1 (en) 2014-12-11
CN103974930B (zh) 2016-09-28
JP2013129640A (ja) 2013-07-04
WO2013094108A1 (ja) 2013-06-27
IN2014MN01086A (https=) 2015-07-03
CN103974930A (zh) 2014-08-06
EP2796444B1 (en) 2017-03-15
US9079826B2 (en) 2015-07-14
EP2796444A1 (en) 2014-10-29

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