JP5695909B2 - 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体 - Google Patents
極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体 Download PDFInfo
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- JP5695909B2 JP5695909B2 JP2010541744A JP2010541744A JP5695909B2 JP 5695909 B2 JP5695909 B2 JP 5695909B2 JP 2010541744 A JP2010541744 A JP 2010541744A JP 2010541744 A JP2010541744 A JP 2010541744A JP 5695909 B2 JP5695909 B2 JP 5695909B2
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008003566.1 | 2008-01-09 | ||
| DE102008003566A DE102008003566A1 (de) | 2008-01-09 | 2008-01-09 | Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil |
| US4466208P | 2008-04-14 | 2008-04-14 | |
| US61/044,662 | 2008-04-14 | ||
| DE102008025007.4 | 2008-05-24 | ||
| DE200810025007 DE102008025007A1 (de) | 2008-05-24 | 2008-05-24 | Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil |
| PCT/EP2009/000018 WO2009087082A2 (de) | 2008-01-09 | 2009-01-06 | Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011509269A JP2011509269A (ja) | 2011-03-24 |
| JP2011509269A5 JP2011509269A5 (OSRAM) | 2012-02-23 |
| JP5695909B2 true JP5695909B2 (ja) | 2015-04-08 |
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| JP2010541744A Expired - Fee Related JP5695909B2 (ja) | 2008-01-09 | 2009-01-06 | 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体 |
Country Status (20)
| Country | Link |
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| US (1) | US8633156B2 (OSRAM) |
| EP (1) | EP2229406B1 (OSRAM) |
| JP (1) | JP5695909B2 (OSRAM) |
| KR (1) | KR20100111683A (OSRAM) |
| CN (1) | CN101970476B (OSRAM) |
| AR (1) | AR070119A1 (OSRAM) |
| AU (1) | AU2009203810B2 (OSRAM) |
| BR (1) | BRPI0907119A2 (OSRAM) |
| CA (1) | CA2711752A1 (OSRAM) |
| CL (1) | CL2009000018A1 (OSRAM) |
| CO (1) | CO6290770A2 (OSRAM) |
| IL (1) | IL206843A0 (OSRAM) |
| MA (1) | MA31997B1 (OSRAM) |
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| PA (1) | PA8811501A1 (OSRAM) |
| PE (1) | PE20091305A1 (OSRAM) |
| TW (1) | TWI433681B (OSRAM) |
| UY (1) | UY31597A1 (OSRAM) |
| WO (1) | WO2009087082A2 (OSRAM) |
| ZA (1) | ZA201003927B (OSRAM) |
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| DE102005046113A1 (de) * | 2005-09-27 | 2007-03-29 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Amidierung von Polypetiden mit C-terminalen basischen Aminosäuren unter Verwendung spezifischer Endoproteasen |
| NZ586590A (en) * | 2008-01-09 | 2012-06-29 | Sanofi Aventis Deutschland | Insulin analogues or derivatives having an extremely delayed time-action profile |
| DK3228320T3 (da) | 2008-10-17 | 2020-03-09 | Sanofi Aventis Deutschland | Kombination af et insulin og en glp-1-agonist |
| BRPI0823377A2 (pt) | 2008-12-15 | 2016-09-27 | Zealand Pharma As | análogos de glucagon |
| DK2370461T3 (da) | 2008-12-15 | 2013-12-16 | Zealand Pharma As | Glucagonanaloger |
| JP5635530B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
| MA32970B1 (fr) | 2008-12-15 | 2012-01-02 | Zealand Pharma As | Analogues du glucagon |
| JP6054742B2 (ja) | 2009-07-13 | 2016-12-27 | ジーランド ファーマ アクティーゼルスカブ | アシル化グルカゴン類似体 |
| PL3417871T3 (pl) | 2009-11-13 | 2021-06-14 | Sanofi-Aventis Deutschland Gmbh | Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę |
| CN102711804B (zh) | 2009-11-13 | 2015-09-16 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂和甲硫氨酸的药物组合物 |
| UY33462A (es) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | Analogos de glucagon |
| KR20230051307A (ko) | 2010-06-24 | 2023-04-17 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
| US9169310B2 (en) | 2010-06-24 | 2015-10-27 | Zealand Pharma A/S | Glucagon analogues |
| RU2546520C2 (ru) | 2010-08-30 | 2015-04-10 | Санофи-Авентис Дойчланд Гмбх | Применение ave0010 для производства лекарственного средства для лечения сахарного диабета 2 типа |
| US20120283169A1 (en) | 2010-11-08 | 2012-11-08 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| PH12013501495A1 (en) | 2011-01-20 | 2013-09-16 | Zealand Pharma As | Combination of acylated glucagon analogues with insulin analogues |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| UA113626C2 (xx) * | 2011-06-02 | 2017-02-27 | Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії | |
| BR112014004726A2 (pt) | 2011-08-29 | 2017-04-04 | Sanofi Aventis Deutschland | combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| JP6228187B2 (ja) | 2012-05-03 | 2017-11-08 | ジーランド ファーマ アクティーゼルスカブ | Ｇｉｐ−ｇｌｐ−１デュアルアゴニスト化合物及び方法 |
| MX356957B (es) | 2012-07-23 | 2018-06-20 | Zealand Pharma As | Analogos del glucagon. |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| TWI641381B (zh) | 2013-02-04 | 2018-11-21 | 法商賽諾菲公司 | 胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物 |
| CA2926314C (en) | 2013-10-17 | 2023-08-29 | Zealand Pharma A/S | Acylated glucagon analogues |
| US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| AU2014345569B2 (en) | 2013-11-06 | 2020-08-13 | Zealand Pharma A/S | GIP-GLP-1 dual agonist compounds and methods |
| CN105829339B (zh) | 2013-11-06 | 2021-03-12 | 西兰制药公司 | 胰高血糖素-glp-1-gip三重激动剂化合物 |
| AU2015205620A1 (en) | 2014-01-09 | 2016-07-14 | Sanofi | Stabilized pharmaceutical formulations of insulin aspart |
| SG11201604708VA (en) | 2014-01-09 | 2016-07-28 | Sanofi Sa | Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives |
| AU2015205624A1 (en) | 2014-01-09 | 2016-07-14 | Sanofi | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives |
| CN116987172A (zh) * | 2014-01-20 | 2023-11-03 | 韩美药品株式会社 | 长效胰岛素及其用途 |
| AR100639A1 (es) | 2014-05-29 | 2016-10-19 | Hanmi Pharm Ind Co Ltd | Composición para tratar diabetes que comprende conjugados de análogos de insulina de acción prolongada y conjugados de péptidos insulinotrópicos de acción prolongada |
| TWI684458B (zh) | 2014-05-30 | 2020-02-11 | 南韓商韓美藥品股份有限公司 | 包含胰島素及ｇｌｐ-１/昇糖素雙重促效劑之治療糖尿病之組成物 |
| EP3212218B1 (en) | 2014-10-29 | 2021-06-30 | Zealand Pharma A/S | Gip agonist compounds and methods |
| ES2949095T3 (es) | 2014-12-12 | 2023-09-25 | Sanofi Aventis Deutschland | Formulación de relación fija de insulina glargina/lixisenatida |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
| CA2980978A1 (en) | 2015-04-16 | 2016-10-20 | Zealand Pharma A/S | Acylated glucagon analogue |
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| CN110546161B (zh) * | 2016-09-23 | 2024-01-26 | 韩美药品股份有限公司 | 对胰岛素受体具有降低的结合力的胰岛素类似物及其用途 |
| EP3604328A4 (en) | 2017-03-23 | 2021-01-06 | Hanmi Pharm. Co., Ltd. | INSULIN ANALOGUE COMPLEX WITH REDUCED AFFINITY FOR THE INSULIN RECEPTOR AND USE OF IT |
| CN110615836B (zh) * | 2018-06-20 | 2022-09-13 | 鲁南制药集团股份有限公司 | 一种利拉鲁肽的固相合成方法 |
| CN115702880B (zh) * | 2021-08-12 | 2023-11-03 | 山东新时代药业有限公司 | 一种重组甘精胰岛素注射液及其制备工艺 |
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2009
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- 2009-01-06 CN CN200980101942.6A patent/CN101970476B/zh not_active Expired - Fee Related
- 2009-01-06 WO PCT/EP2009/000018 patent/WO2009087082A2/de not_active Ceased
- 2009-01-06 CA CA2711752A patent/CA2711752A1/en not_active Abandoned
- 2009-01-06 KR KR1020107014964A patent/KR20100111683A/ko not_active Ceased
- 2009-01-06 EP EP09700949.2A patent/EP2229406B1/de active Active
- 2009-01-06 BR BRPI0907119-9A patent/BRPI0907119A2/pt not_active Application Discontinuation
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- 2009-01-07 TW TW098100283A patent/TWI433681B/zh not_active IP Right Cessation
- 2009-01-07 UY UY031597A patent/UY31597A1/es not_active Application Discontinuation
- 2009-01-07 AR ARP090100036A patent/AR070119A1/es unknown
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- 2009-01-07 CL CL2009000018A patent/CL2009000018A1/es unknown
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- 2010-06-25 CO CO10076884A patent/CO6290770A2/es not_active Application Discontinuation
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Also Published As
| Publication number | Publication date |
|---|---|
| US20110173722A1 (en) | 2011-07-14 |
| KR20100111683A (ko) | 2010-10-15 |
| EP2229406A2 (de) | 2010-09-22 |
| AR070119A1 (es) | 2010-03-17 |
| PE20091305A1 (es) | 2009-09-26 |
| UY31597A1 (es) | 2009-08-31 |
| US8633156B2 (en) | 2014-01-21 |
| WO2009087082A2 (de) | 2009-07-16 |
| ZA201003927B (en) | 2011-04-28 |
| EP2229406B1 (de) | 2015-04-22 |
| TWI433681B (zh) | 2014-04-11 |
| CN101970476B (zh) | 2014-08-27 |
| AU2009203810B2 (en) | 2013-07-25 |
| IL206843A0 (en) | 2010-12-30 |
| NZ586589A (en) | 2012-04-27 |
| BRPI0907119A2 (pt) | 2015-07-14 |
| WO2009087082A3 (de) | 2009-09-24 |
| PA8811501A1 (es) | 2009-09-17 |
| TW200942257A (en) | 2009-10-16 |
| CL2009000018A1 (es) | 2009-06-05 |
| CN101970476A (zh) | 2011-02-09 |
| MA31997B1 (fr) | 2011-01-03 |
| AU2009203810A1 (en) | 2009-07-16 |
| HK1148542A1 (en) | 2011-09-09 |
| JP2011509269A (ja) | 2011-03-24 |
| CA2711752A1 (en) | 2009-07-16 |
| CO6290770A2 (es) | 2011-06-20 |
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