JP5525880B2 - 走査型レーザ顕微鏡 - Google Patents

走査型レーザ顕微鏡 Download PDF

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Publication number
JP5525880B2
JP5525880B2 JP2010065909A JP2010065909A JP5525880B2 JP 5525880 B2 JP5525880 B2 JP 5525880B2 JP 2010065909 A JP2010065909 A JP 2010065909A JP 2010065909 A JP2010065909 A JP 2010065909A JP 5525880 B2 JP5525880 B2 JP 5525880B2
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Japan
Prior art keywords
laser
dichroic mirror
optical system
scanning
sample
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JP2010065909A
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English (en)
Japanese (ja)
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JP2010152397A (ja
JP2010152397A5 (enExample
Inventor
靖晃 名取
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Olympus Corp
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Olympus Corp
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Priority to JP2010065909A priority Critical patent/JP5525880B2/ja
Publication of JP2010152397A publication Critical patent/JP2010152397A/ja
Publication of JP2010152397A5 publication Critical patent/JP2010152397A5/ja
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/32—Micromanipulators structurally combined with microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2010065909A 2002-08-29 2010-03-23 走査型レーザ顕微鏡 Expired - Lifetime JP5525880B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010065909A JP5525880B2 (ja) 2002-08-29 2010-03-23 走査型レーザ顕微鏡

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002250824 2002-08-29
JP2002250824 2002-08-29
JP2010065909A JP5525880B2 (ja) 2002-08-29 2010-03-23 走査型レーザ顕微鏡

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2003304711A Division JP2004110017A (ja) 2002-08-29 2003-08-28 走査型レーザ顕微鏡

Publications (3)

Publication Number Publication Date
JP2010152397A JP2010152397A (ja) 2010-07-08
JP2010152397A5 JP2010152397A5 (enExample) 2010-08-19
JP5525880B2 true JP5525880B2 (ja) 2014-06-18

Family

ID=32948299

Family Applications (1)

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JP2010065909A Expired - Lifetime JP5525880B2 (ja) 2002-08-29 2010-03-23 走査型レーザ顕微鏡

Country Status (2)

Country Link
US (1) US7223986B2 (enExample)
JP (1) JP5525880B2 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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US20030219094A1 (en) * 2002-05-21 2003-11-27 Basting Dirk L. Excimer or molecular fluorine laser system with multiple discharge units
DE102004044626B4 (de) * 2004-09-13 2008-11-20 Leica Microsystems Cms Gmbh Verfahren zur Untersuchung von Transportprozessen
TWI364889B (en) * 2005-11-11 2012-05-21 Hon Hai Prec Ind Co Ltd Laser device and laser system using the same
EP2042905B1 (en) * 2006-07-03 2016-04-13 Nikon Corporation Laser scanning microscope
JP5287252B2 (ja) 2006-12-22 2013-09-11 株式会社ニコン レーザ走査共焦点顕微鏡
EP1953579B1 (en) * 2007-02-05 2010-01-13 Olympus Corporation Scanning laser microscope
JP5058625B2 (ja) * 2007-02-19 2012-10-24 オリンパス株式会社 レーザ顕微鏡
GB0721343D0 (en) * 2007-10-30 2007-12-19 Perkinelmer Ltd Improvements in and relating to scanning confocal microscopy
CN102215736B (zh) 2008-11-18 2015-04-29 斯特赖克公司 具有反馈控制系统的内窥镜led光源
JP5452180B2 (ja) * 2009-11-13 2014-03-26 オリンパス株式会社 顕微鏡装置
DE102010044503B4 (de) * 2010-09-06 2017-11-02 Leica Microsystems (Schweiz) Ag Fluoreszenz-Operations-Stereomikroskop
EP3640701B1 (en) 2011-10-25 2022-06-15 Daylight Solutions Inc. Infrared imaging microscope using tunable laser radiation
WO2013161899A1 (ja) * 2012-04-27 2013-10-31 オリンパス株式会社 顕微鏡装置および顕微鏡装置の電動光学ユニットの制御方法
JP5991850B2 (ja) * 2012-05-11 2016-09-14 オリンパス株式会社 顕微鏡装置
EP2967299B1 (en) 2013-03-15 2022-11-30 Stryker Corporation Endoscopic light source and imaging system
EP2984514B9 (en) 2013-04-12 2021-04-07 Daylight Solutions Inc. Infrared refractive objective lens assembly
DE102013022026A1 (de) 2013-12-19 2015-06-25 Carl Zeiss Microscopy Gmbh Mehrfarben-Scanning-Mikroskop
JP6539508B2 (ja) 2015-06-12 2019-07-03 オリンパス株式会社 顕微鏡システム
JP6636756B2 (ja) * 2015-09-10 2020-01-29 株式会社東芝 光学装置及び加工装置
TWI619937B (zh) * 2016-01-15 2018-04-01 奇美視像科技股份有限公司 以多光子激發技術檢查物體之方法以及量測物體之裝置
JP6583442B2 (ja) * 2016-02-19 2019-10-02 株式会社ニコン 試料作製方法および試料作製装置
US10634575B2 (en) * 2016-03-31 2020-04-28 Konica Minolta Laboratory U.S.A., Inc. Laser scanning leak detection and visualization apparatus
US10690904B2 (en) 2016-04-12 2020-06-23 Stryker Corporation Multiple imaging modality light source
CN108072613B (zh) * 2016-11-11 2020-09-08 台湾积体电路制造股份有限公司 光学检测装置及其检测方法
US10928617B1 (en) * 2018-05-18 2021-02-23 GDH Enterprises, LLC Portable three-dimensional virtual imaging device
GB2588378A (en) * 2019-10-10 2021-04-28 Refeyn Ltd Methods and apparatus for optimised interferometric scattering microscopy
WO2021101893A1 (en) * 2019-11-19 2021-05-27 Fluidigm Corporation Laser capture microdissection apparatus, system and method
DE102024108046A1 (de) * 2024-03-20 2025-09-25 Carl Zeiss Microscopy Gmbh Superauflösendes Mikroskop mit schneller quasikonfokaler Detektion

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4893886A (en) * 1987-09-17 1990-01-16 American Telephone And Telegraph Company Non-destructive optical trap for biological particles and method of doing same
GB9218482D0 (en) * 1992-09-01 1992-10-14 Dixon Arthur E Apparatus and method for scanning laser imaging of macroscopic samples
JP3849176B2 (ja) * 1996-06-11 2006-11-22 株式会社ニコン 光走査型顕微鏡
JP3917731B2 (ja) * 1996-11-21 2007-05-23 オリンパス株式会社 レーザ走査顕微鏡
US6167173A (en) * 1997-01-27 2000-12-26 Carl Zeiss Jena Gmbh Laser scanning microscope
JP2002526788A (ja) * 1998-09-30 2002-08-20 トレリス バイオインファーマティック インコーポレイテッド ハイスループット顕微鏡
US6429936B1 (en) * 1998-11-06 2002-08-06 C&L Instruments Synchronous multiwavelength fluorescence system
JP3283499B2 (ja) * 1999-03-18 2002-05-20 オリンパス光学工業株式会社 レーザ顕微鏡
JP4468507B2 (ja) 1999-03-24 2010-05-26 オリンパス株式会社 走査型レーザ顕微鏡
WO2002035260A2 (en) * 2000-10-27 2002-05-02 Molecular Devices Corporation Light detection device
US6888148B2 (en) * 2001-12-10 2005-05-03 Carl Zeiss Jena Gmbh Arrangement for the optical capture of excited and /or back scattered light beam in a sample
US6768122B2 (en) * 2002-06-04 2004-07-27 National Taiwan University Multiphoton excitation microscope for biochip fluorescence assay

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Publication number Publication date
JP2010152397A (ja) 2010-07-08
US7223986B2 (en) 2007-05-29
US20040178356A1 (en) 2004-09-16

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