JP5480813B2 - Ｊａｎｕｓキナーゼ阻害剤としての置換複素環 - Google Patents

Ｊａｎｕｓキナーゼ阻害剤としての置換複素環 Download PDF

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JP5480813B2
JP5480813B2 JP2010534154A JP2010534154A JP5480813B2 JP 5480813 B2 JP5480813 B2 JP 5480813B2 JP 2010534154 A JP2010534154 A JP 2010534154A JP 2010534154 A JP2010534154 A JP 2010534154A JP 5480813 B2 JP5480813 B2 JP 5480813B2
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pyrazol
pyrimidin
phenylamino
ylamino
cyano
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Expired - Fee Related
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JP2011503194A5 (OSRAM
JP2011503194A (ja
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ユン−ロン・リ
ウェンキン・ヤオ
ジェイムズ・ディ・ロジャース
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Incyte Corp
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Incyte Corp
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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JP2010534154A 2007-11-16 2008-11-13 Ｊａｎｕｓキナーゼ阻害剤としての置換複素環 Expired - Fee Related JP5480813B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
US60/988,606 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

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JP2011503194A JP2011503194A (ja) 2011-01-27
JP2011503194A5 JP2011503194A5 (OSRAM) 2012-01-05
JP5480813B2 true JP5480813B2 (ja) 2014-04-23

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US (1) US8309718B2 (OSRAM)
EP (1) EP2220068B1 (OSRAM)
JP (1) JP5480813B2 (OSRAM)
KR (1) KR101580482B1 (OSRAM)
CN (1) CN101910152B (OSRAM)
AU (1) AU2008321046B2 (OSRAM)
BR (1) BRPI0820544A2 (OSRAM)
CA (1) CA2704599C (OSRAM)
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MX (1) MX2010005300A (OSRAM)
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NZ (1) NZ585139A (OSRAM)
UA (1) UA104849C2 (OSRAM)
WO (1) WO2009064835A1 (OSRAM)
ZA (1) ZA201004055B (OSRAM)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
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US20060106020A1 (en) * 2004-04-28 2006-05-18 Rodgers James D Tetracyclic inhibitors of Janus kinases
PT1966202E (pt) 2005-12-13 2012-01-03 Incyte Corp Pirrolo[2,3-b] pirimidinas e pirrolo[2,3-b]piridinas substituídas com heteroarilo como inibidores de janus quinase
EP2121692B1 (en) * 2006-12-22 2013-04-10 Incyte Corporation Substituted heterocycles as janus kinase inhibitors
RS53245B2 (sr) 2007-06-13 2022-10-31 Incyte Holdings Corp Soli inhibitora janus kinaze (r)-3-(4-(7h-pirolo(2,3-d) pirimidin-4-il)-1h-pirazol-1-il)-3-ciklopentilpropan-nitrila
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
FR2938537B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
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AU2008321046B2 (en) 2013-10-24
CA2704599C (en) 2015-05-12
IL205571A (en) 2015-09-24
UA104849C2 (uk) 2014-03-25
BRPI0820544A2 (pt) 2015-06-16
EA020777B1 (ru) 2015-01-30
HK1147476A1 (zh) 2011-08-12
KR101580482B1 (ko) 2015-12-28
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MX2010005300A (es) 2010-06-25

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