JP5457830B2 - オルガノゾル被膜を含む制御放出送達デバイス - Google Patents
オルガノゾル被膜を含む制御放出送達デバイス Download PDFInfo
- Publication number
- JP5457830B2 JP5457830B2 JP2009503379A JP2009503379A JP5457830B2 JP 5457830 B2 JP5457830 B2 JP 5457830B2 JP 2009503379 A JP2009503379 A JP 2009503379A JP 2009503379 A JP2009503379 A JP 2009503379A JP 5457830 B2 JP5457830 B2 JP 5457830B2
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- JP
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- Prior art keywords
- controlled release
- coating
- polymer
- water
- delivery device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
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- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
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- A61K9/5005—Wall or coating material
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39616606A | 2006-04-03 | 2006-04-03 | |
| US11/396,166 | 2006-04-03 | ||
| PCT/CA2007/000550 WO2007112581A1 (en) | 2006-04-03 | 2007-04-03 | Controlled release delivery device comprising an organosol coat |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009532389A JP2009532389A (ja) | 2009-09-10 |
| JP2009532389A5 JP2009532389A5 (enExample) | 2010-05-20 |
| JP5457830B2 true JP5457830B2 (ja) | 2014-04-02 |
Family
ID=38563053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009503379A Expired - Fee Related JP5457830B2 (ja) | 2006-04-03 | 2007-04-03 | オルガノゾル被膜を含む制御放出送達デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9561188B2 (enExample) |
| EP (1) | EP2007360B1 (enExample) |
| JP (1) | JP5457830B2 (enExample) |
| CN (2) | CN101453993A (enExample) |
| CA (1) | CA2648280C (enExample) |
| WO (1) | WO2007112581A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US10064828B1 (en) * | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| US9561188B2 (en) | 2006-04-03 | 2017-02-07 | Intellipharmaceutics Corporation | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| CN102223893B (zh) * | 2008-07-22 | 2014-07-16 | 曼诺吉尼克斯公司 | 治疗与绝经、激素改变和关节炎相关的症状的组合物和方法 |
| CA2732655A1 (en) * | 2008-07-31 | 2010-02-04 | Feyecon B.V. | Microencapsulate and process for the manufacture thereof |
| EP2452677A1 (en) * | 2008-09-29 | 2012-05-16 | Wockhardt Limited | Extended release dosage form of ropinirole |
| JP2012515765A (ja) * | 2009-01-22 | 2012-07-12 | アボット ヘルスケア プライベート リミテッド | 時間治療用医薬組成物 |
| CN101966203A (zh) * | 2009-07-28 | 2011-02-09 | 安徽中医学院 | 中药复方有效成分群的释放技术研究与应用 |
| CN102039000B (zh) * | 2009-10-20 | 2015-08-26 | 苏州纳通生物纳米技术有限公司 | 一种透皮给药试剂盒 |
| CN101716162B (zh) * | 2009-11-26 | 2012-11-14 | 扬州中宝制药有限公司 | 一种氨茶碱缓释胶囊及其制备方法 |
| BR112012013487A2 (pt) | 2009-12-02 | 2017-10-03 | Adamas Pharmaceuticals Inc | Composições de amantadina e métodos de uso |
| US9415048B2 (en) | 2010-07-08 | 2016-08-16 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
| US9119793B1 (en) | 2011-06-28 | 2015-09-01 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for doxycycline |
| CN102274205B (zh) * | 2011-07-21 | 2013-03-13 | 佛山市隆信医药科技有限公司 | 琥珀酸美托洛尔的缓释胶囊及制备方法 |
| CN102525999A (zh) * | 2011-12-06 | 2012-07-04 | 广州科的信医药技术有限公司 | 一种富马酸酮替芬缓释胶囊及其制备方法 |
| US10105330B2 (en) | 2012-01-04 | 2018-10-23 | Wellesley Pharmaceuticals, Llc | Extended, delayed and immediate release formulation method of manufacturing and use thereof |
| US10278925B2 (en) | 2012-01-04 | 2019-05-07 | Wellesley Pharmaceuticals, Llc | Delayed-release formulations, methods of making and use thereof |
| WO2013103357A1 (en) * | 2012-01-04 | 2013-07-11 | Wellesley Pharmaceutical | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| CN102600108A (zh) * | 2012-01-17 | 2012-07-25 | 广州科的信医药技术有限公司 | 一种氟比洛芬缓释胶囊及其制备方法 |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| US8545878B1 (en) | 2012-11-09 | 2013-10-01 | Civitas Therapeutics, Inc. | Capsules containing high doses of levodopa for pulmonary use |
| US20160367502A1 (en) * | 2012-12-19 | 2016-12-22 | Ratiopharm Gmbh | Film coated pellets |
| US20140230769A1 (en) * | 2013-02-15 | 2014-08-21 | GM Global Technology Operations LLC | Polymeric engine component having integrated oil additive |
| GB201304662D0 (en) * | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| US10842802B2 (en) | 2013-03-15 | 2020-11-24 | Medicis Pharmaceutical Corporation | Controlled release pharmaceutical dosage forms |
| CN103236208B (zh) * | 2013-04-19 | 2015-01-28 | 东南大学 | 定量研究颗粒粘性力对流化床气固流动影响的实验方法 |
| WO2014204933A1 (en) | 2013-06-17 | 2014-12-24 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
| AU2014306759B2 (en) | 2013-08-12 | 2018-04-26 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| MX2016007786A (es) * | 2013-12-16 | 2017-03-03 | Massachusetts Inst Technology | Formulaciones de sal de micronutrientes fortificadas. |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2016010771A1 (en) | 2014-07-17 | 2016-01-21 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| US9586371B2 (en) | 2014-09-02 | 2017-03-07 | Empire Technology Development Llc | Method of bonding material layers in an additive manufacturing process |
| US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
| CA2964628A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CN107108442A (zh) | 2014-11-14 | 2017-08-29 | 燿石治疗公司 | 用于制备α,ω‑二羧酸封端的二烷醚的方法和中间体 |
| WO2016114812A1 (en) * | 2015-01-12 | 2016-07-21 | Robert Niichel | Layered sustained-release microbeads and methods of making the same |
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2007
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- 2007-04-03 CN CNA2007800193727A patent/CN101453993A/zh active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| US20090220613A1 (en) | 2009-09-03 |
| US9561188B2 (en) | 2017-02-07 |
| EP2007360B1 (en) | 2014-11-26 |
| CN101453993A (zh) | 2009-06-10 |
| EP2007360A4 (en) | 2012-10-03 |
| CA2648280A1 (en) | 2007-10-11 |
| US20170112770A1 (en) | 2017-04-27 |
| US10159649B2 (en) | 2018-12-25 |
| WO2007112581A1 (en) | 2007-10-11 |
| US20190076363A1 (en) | 2019-03-14 |
| US10314787B2 (en) | 2019-06-11 |
| JP2009532389A (ja) | 2009-09-10 |
| CA2648280C (en) | 2014-03-11 |
| CN104825397A (zh) | 2015-08-12 |
| EP2007360A1 (en) | 2008-12-31 |
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