JP5302197B2 - 両親媒性コポリマーおよび調節放出の有効成分を基にした微小粒子、ならびにこれらを含む医薬製剤 - Google Patents
両親媒性コポリマーおよび調節放出の有効成分を基にした微小粒子、ならびにこれらを含む医薬製剤 Download PDFInfo
- Publication number
- JP5302197B2 JP5302197B2 JP2009525938A JP2009525938A JP5302197B2 JP 5302197 B2 JP5302197 B2 JP 5302197B2 JP 2009525938 A JP2009525938 A JP 2009525938A JP 2009525938 A JP2009525938 A JP 2009525938A JP 5302197 B2 JP5302197 B2 JP 5302197B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- microparticles
- polymer
- solution
- pharmaceutical formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0653191A FR2904219B1 (fr) | 2006-07-28 | 2006-07-28 | Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant |
FR0653191 | 2006-07-28 | ||
PCT/EP2007/006722 WO2008025425A1 (fr) | 2006-07-28 | 2007-07-30 | Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2009544759A JP2009544759A (ja) | 2009-12-17 |
JP2009544759A5 JP2009544759A5 (zh) | 2010-09-16 |
JP5302197B2 true JP5302197B2 (ja) | 2013-10-02 |
Family
ID=37814390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009525938A Expired - Fee Related JP5302197B2 (ja) | 2006-07-28 | 2007-07-30 | 両親媒性コポリマーおよび調節放出の有効成分を基にした微小粒子、ならびにこれらを含む医薬製剤 |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP2049085A1 (zh) |
JP (1) | JP5302197B2 (zh) |
KR (1) | KR101407033B1 (zh) |
CN (1) | CN101568328B (zh) |
BR (1) | BRPI0714943A2 (zh) |
CA (1) | CA2661567C (zh) |
FR (1) | FR2904219B1 (zh) |
IL (1) | IL196426A (zh) |
MX (1) | MX2009000951A (zh) |
WO (1) | WO2008025425A1 (zh) |
ZA (1) | ZA200900929B (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2934161B1 (fr) * | 2008-07-28 | 2010-09-17 | Flamel Tech Sa | Forme orale microparticulaire utile pour la liberation modifiee de nanoparticules. |
FR2940619B1 (fr) * | 2008-12-31 | 2012-02-10 | Flamel Technologies Sa | Composition comprenant un actif de solubilite aqueuse faible ou moyenne |
FR2954325B1 (fr) | 2009-12-23 | 2012-02-03 | Flamel Tech Sa | Polymere amphiphile fonctionnalise par la methionine |
JP4829351B2 (ja) * | 2010-02-05 | 2011-12-07 | ナノキャリア株式会社 | 易崩壊型ポリマーミセル組成物 |
CN102232932B (zh) * | 2010-04-27 | 2013-06-05 | 重庆莱美药业股份有限公司 | 果胶-阿霉素轭合物的冻干制剂及制备方法 |
CN102657843A (zh) * | 2012-06-05 | 2012-09-12 | 云南民族大学 | 抗菌肽组合物及其制备方法 |
CN103483583B (zh) * | 2013-09-24 | 2015-11-18 | 昆明理工大学 | 一种ε-聚赖氨酸的制备方法 |
WO2015151103A1 (en) * | 2014-04-03 | 2015-10-08 | Biondvax Pharmaceuticals Ltd. | Compositions of multimeric-multiepitope influenza polypeptides and their production |
AU2015338717B2 (en) | 2014-10-31 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
KR101891715B1 (ko) * | 2016-01-15 | 2018-08-27 | 연세대학교 산학협력단 | 바이러스 감염의 치료용 폴리아미노산 기반의 생체환경 감응형 나노입자 |
WO2018025699A1 (ja) * | 2016-08-02 | 2018-02-08 | 日本化薬株式会社 | アクティブターゲティング型高分子誘導体、その高分子誘導体を含む組成物、及びそれらの用途 |
CN110483785B (zh) * | 2019-07-01 | 2020-05-19 | 中山大学 | 一种三嵌段聚合物、载药纳米胶束、纳米药物及其制备方法和应用 |
CN110343245B (zh) * | 2019-07-16 | 2021-09-28 | 天津大学 | 一种ε-聚赖氨酸-接枝-疏水氨基酸-接枝-海藻糖的糖肽及制备方法 |
CN112553759A (zh) * | 2020-11-30 | 2021-03-26 | 福建凤竹纺织科技股份有限公司 | 一种多功能海藻纤维针织面料 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4002736A1 (de) * | 1990-01-31 | 1991-08-01 | Hoechst Ag | Biologisch abbaubare polymere, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe |
US5250293A (en) * | 1991-04-22 | 1993-10-05 | Gleich Gerald J | Method for the treatment of hypersensitivity diseases by administration of anionic polymers |
GB9221329D0 (en) * | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
DE4407898A1 (de) * | 1994-03-09 | 1995-09-14 | Hoechst Ag | Nanopartikel, enthaltend einen Wirkstoff und ein Polyketalweinsäureamid, Verfahren zu ihrer Herstellung und Verwendung derselben |
DK1071407T3 (da) * | 1999-01-18 | 2014-10-20 | Lg Life Sciences Ltd | Lipofile mikropartikler indeholdende et proteinlægemiddel eller et antigen og formulering omhandlende samme |
FR2814951B1 (fr) * | 2000-10-06 | 2003-01-17 | Flamel Tech Sa | Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation |
WO2003035051A2 (en) * | 2001-10-19 | 2003-05-01 | Inhale Therapeutic Systems, Inc. | The use of proton sequestering agents in drug formulations |
FR2862536B1 (fr) * | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques |
FR2862541B1 (fr) * | 2003-11-21 | 2007-04-20 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee d'interferons et leurs applications therapeutiques |
FR2862535B1 (fr) * | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee d'interleukines et leurs applications therapeutiques |
-
2006
- 2006-07-28 FR FR0653191A patent/FR2904219B1/fr not_active Expired - Fee Related
-
2007
- 2007-07-30 KR KR1020097004345A patent/KR101407033B1/ko not_active IP Right Cessation
- 2007-07-30 JP JP2009525938A patent/JP5302197B2/ja not_active Expired - Fee Related
- 2007-07-30 EP EP07801468A patent/EP2049085A1/fr not_active Withdrawn
- 2007-07-30 BR BRPI0714943-3A patent/BRPI0714943A2/pt not_active IP Right Cessation
- 2007-07-30 MX MX2009000951A patent/MX2009000951A/es active IP Right Grant
- 2007-07-30 ZA ZA200900929A patent/ZA200900929B/xx unknown
- 2007-07-30 CA CA2661567A patent/CA2661567C/fr active Active
- 2007-07-30 WO PCT/EP2007/006722 patent/WO2008025425A1/fr active Application Filing
- 2007-07-30 CN CN2007800318934A patent/CN101568328B/zh not_active Expired - Fee Related
-
2009
- 2009-01-11 IL IL196426A patent/IL196426A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL196426A (en) | 2014-07-31 |
KR101407033B1 (ko) | 2014-06-20 |
CA2661567A1 (fr) | 2008-03-06 |
CN101568328A (zh) | 2009-10-28 |
CA2661567C (fr) | 2016-09-20 |
WO2008025425A1 (fr) | 2008-03-06 |
AU2007291577A1 (en) | 2008-03-06 |
WO2008025425B1 (fr) | 2008-05-02 |
MX2009000951A (es) | 2009-02-04 |
FR2904219A1 (fr) | 2008-02-01 |
WO2008025425A8 (fr) | 2009-04-16 |
WO2008025425A9 (fr) | 2008-06-12 |
ZA200900929B (en) | 2010-06-30 |
EP2049085A1 (fr) | 2009-04-22 |
CN101568328B (zh) | 2012-09-05 |
KR20090054976A (ko) | 2009-06-01 |
BRPI0714943A2 (pt) | 2013-05-21 |
FR2904219B1 (fr) | 2010-08-13 |
JP2009544759A (ja) | 2009-12-17 |
IL196426A0 (en) | 2009-09-22 |
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