FR2954325B1 - Polymere amphiphile fonctionnalise par la methionine - Google Patents

Polymere amphiphile fonctionnalise par la methionine

Info

Publication number
FR2954325B1
FR2954325B1 FR0959460A FR0959460A FR2954325B1 FR 2954325 B1 FR2954325 B1 FR 2954325B1 FR 0959460 A FR0959460 A FR 0959460A FR 0959460 A FR0959460 A FR 0959460A FR 2954325 B1 FR2954325 B1 FR 2954325B1
Authority
FR
France
Prior art keywords
methionine
amphiphilic polymer
polymer functionalized
active agent
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0959460A
Other languages
English (en)
Other versions
FR2954325A1 (fr
Inventor
You-Ping Chan
Corine Vialas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0959460A priority Critical patent/FR2954325B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to JP2012545519A priority patent/JP2013515809A/ja
Priority to EP10816323A priority patent/EP2516508A2/fr
Priority to PCT/IB2010/056041 priority patent/WO2011077402A2/fr
Priority to CA2784849A priority patent/CA2784849A1/fr
Priority to US12/977,816 priority patent/US20110150837A1/en
Priority to CN2010800592860A priority patent/CN102666653A/zh
Publication of FR2954325A1 publication Critical patent/FR2954325A1/fr
Application granted granted Critical
Publication of FR2954325B1 publication Critical patent/FR2954325B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/42—Polyamides containing atoms other than carbon, hydrogen, oxygen, and nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0959460A 2009-12-23 2009-12-23 Polymere amphiphile fonctionnalise par la methionine Expired - Fee Related FR2954325B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0959460A FR2954325B1 (fr) 2009-12-23 2009-12-23 Polymere amphiphile fonctionnalise par la methionine
EP10816323A EP2516508A2 (fr) 2009-12-23 2010-12-23 Polymere amphiphile fonctionnalise par la methionine
PCT/IB2010/056041 WO2011077402A2 (fr) 2009-12-23 2010-12-23 Polymere amphiphile fonctionnalise par la methionine
CA2784849A CA2784849A1 (fr) 2009-12-23 2010-12-23 Polymere amphiphile fonctionnalise par la methionine
JP2012545519A JP2013515809A (ja) 2009-12-23 2010-12-23 メチオニンにより官能基化された両親媒性ポリマー
US12/977,816 US20110150837A1 (en) 2009-12-23 2010-12-23 Amphiphilic polymer functionalized by methionine
CN2010800592860A CN102666653A (zh) 2009-12-23 2010-12-23 通过蛋氨酸官能化的两亲聚合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0959460A FR2954325B1 (fr) 2009-12-23 2009-12-23 Polymere amphiphile fonctionnalise par la methionine

Publications (2)

Publication Number Publication Date
FR2954325A1 FR2954325A1 (fr) 2011-06-24
FR2954325B1 true FR2954325B1 (fr) 2012-02-03

Family

ID=42236955

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0959460A Expired - Fee Related FR2954325B1 (fr) 2009-12-23 2009-12-23 Polymere amphiphile fonctionnalise par la methionine

Country Status (6)

Country Link
EP (1) EP2516508A2 (fr)
JP (1) JP2013515809A (fr)
CN (1) CN102666653A (fr)
CA (1) CA2784849A1 (fr)
FR (1) FR2954325B1 (fr)
WO (1) WO2011077402A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6444310B2 (ja) * 2013-10-28 2018-12-26 テルモ株式会社 モノクローナル抗体の安定化方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272135A (en) 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
JPH05291152A (ja) * 1992-04-15 1993-11-05 Hitachi Ltd Ｘ線分析装置及びこれを用いた半導体製造装置
DE4433101A1 (de) 1994-09-16 1996-03-21 Bauer Kurt Heinz Prof Dr Wasserlösliche Dextranfettsäureester und ihre Verwendung als Solubilisatoren
FR2738835B1 (fr) 1995-09-18 1997-10-17 Oreal Composition epaissie en milieu aqueux, procede d'epaississement d'un milieu aqueux et utilisations en cosmetique
KR100541752B1 (ko) 1998-08-31 2006-01-10 니혼유시 가부시기가이샤 고순도 소수성기함유다당류 및 그 제조방법
GB9819461D0 (en) 1998-09-08 1998-10-28 Univ Strathclyde Hydrogels
FR2786098B1 (fr) 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
FR2801226B1 (fr) 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
US20030104996A1 (en) 2001-08-30 2003-06-05 Tiansheng Li L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
FR2840614B1 (fr) * 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2862535B1 (fr) 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee d'interleukines et leurs applications therapeutiques
JP4101191B2 (ja) * 2004-02-16 2008-06-18 独立行政法人科学技術振興機構 温度応答性ペプチドコポリマーゲルを用いた液中物質捕集材料
JP2007191643A (ja) * 2006-01-20 2007-08-02 Mitsui Chemicals Inc 生体への定着性が付与されたポリアミノ酸誘導体
WO2007095288A2 (fr) * 2006-02-13 2007-08-23 Nektar Therapeutics Compositions protéiques ou peptidiques protéine contenant de la méthionine et leur procédé de fabrication et d'utilisation
US8679540B2 (en) * 2006-06-09 2014-03-25 Flamel Technologies Pharmaceutical formulations for the prolonged release of active principle(s), and their applications, especially therapeutic applications
FR2902007B1 (fr) * 2006-06-09 2012-01-13 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s) ainsi que leurs applications notamment therapeutiques
FR2904219B1 (fr) 2006-07-28 2010-08-13 Flamel Tech Sa Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant
EP2125028A1 (fr) * 2007-01-31 2009-12-02 Agency for Science, Technology And Research Nanoparticules revêtues de polymères
FR2915684B1 (fr) 2007-05-03 2011-01-14 Flamel Tech Sa Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules
WO2008145323A1 (fr) 2007-05-31 2008-12-04 F. Hoffmann-La Roche Ag Formulation pharmaceutique comprenant des interférons

Also Published As

Publication number Publication date
WO2011077402A3 (fr) 2011-08-18
FR2954325A1 (fr) 2011-06-24
JP2013515809A (ja) 2013-05-09
CN102666653A (zh) 2012-09-12
WO2011077402A2 (fr) 2011-06-30
EP2516508A2 (fr) 2012-10-31
CA2784849A1 (fr) 2011-06-30

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20150831