JP5213723B2 - マイクロｒｎａの調節に使用するためのオリゴマー化合物及び組成物 - Google Patents

マイクロｒｎａの調節に使用するためのオリゴマー化合物及び組成物 Download PDF

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JP5213723B2
JP5213723B2 JP2008552606A JP2008552606A JP5213723B2 JP 5213723 B2 JP5213723 B2 JP 5213723B2 JP 2008552606 A JP2008552606 A JP 2008552606A JP 2008552606 A JP2008552606 A JP 2008552606A JP 5213723 B2 JP5213723 B2 JP 5213723B2
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chemical formula
oligomeric compound
nucleosides
oligomeric
modified
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JP2009524696A (ja
JP2009524696A5 (https=
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エサウ、クリスティン
スウェイジ、エリック、イー．
バット、バークリシェン
キンバーガー、ガース、エー．
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Ionis Pharmaceuticals Inc
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Isis Pharmaceuticals Inc
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
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    • C12N2320/00—Applications; Uses
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    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2008552606A 2006-01-27 2007-01-27 マイクロｒｎａの調節に使用するためのオリゴマー化合物及び組成物 Active JP5213723B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76272106P 2006-01-27 2006-01-27
US60/762,721 2006-01-27
US80520406P 2006-06-19 2006-06-19
US60/805,204 2006-06-19
PCT/US2007/061186 WO2007090073A2 (en) 2006-01-27 2007-01-27 Oligomeric compounds and compositions for the use in modulation of micrornas

Publications (3)

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JP2009524696A JP2009524696A (ja) 2009-07-02
JP2009524696A5 JP2009524696A5 (https=) 2010-03-04
JP5213723B2 true JP5213723B2 (ja) 2013-06-19

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JP2008552606A Active JP5213723B2 (ja) 2006-01-27 2007-01-27 マイクロｒｎａの調節に使用するためのオリゴマー化合物及び組成物

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US (3) US8129515B2 (https=)
EP (3) EP1984499B1 (https=)
JP (1) JP5213723B2 (https=)
AU (1) AU2007211082B2 (https=)
CA (1) CA2640058C (https=)
WO (1) WO2007090073A2 (https=)

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