JP5111113B2 - Ｒａｆキナーゼ阻害剤として有用なピリドピリミジノン、ジヒドロピリミドピリミジノンおよびプテリジノン - Google Patents

Ｒａｆキナーゼ阻害剤として有用なピリドピリミジノン、ジヒドロピリミドピリミジノンおよびプテリジノン Download PDF

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JP5111113B2
JP5111113B2 JP2007545694A JP2007545694A JP5111113B2 JP 5111113 B2 JP5111113 B2 JP 5111113B2 JP 2007545694 A JP2007545694 A JP 2007545694A JP 2007545694 A JP2007545694 A JP 2007545694A JP 5111113 B2 JP5111113 B2 JP 5111113B2
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pharmaceutically acceptable
acceptable salt
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hydrogen
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JP2008523099A (ja
JP2008523099A5 (enExample
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ヨハン ディー． オスロブ，
チヤン チュ，
ケネス バー，
ジェニファー クロスロー，
ブライアン レイムンド，
ヒロコ タナカ，
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サネシス ファーマシューティカルズ， インコーポレイテッド
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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JP2007545694A 2004-12-13 2005-12-12 Ｒａｆキナーゼ阻害剤として有用なピリドピリミジノン、ジヒドロピリミドピリミジノンおよびプテリジノン Expired - Fee Related JP5111113B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US63564404P 2004-12-13 2004-12-13
US60/635,644 2004-12-13
US63674004P 2004-12-16 2004-12-16
US60/636,740 2004-12-16
US11/301,311 US7767687B2 (en) 2004-12-13 2005-12-12 Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors
US11/301,311 2005-12-12
PCT/US2005/044804 WO2006065703A1 (en) 2004-12-13 2005-12-12 Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors

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JP2008523099A JP2008523099A (ja) 2008-07-03
JP2008523099A5 JP2008523099A5 (enExample) 2009-02-26
JP5111113B2 true JP5111113B2 (ja) 2012-12-26

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US (2) US7767687B2 (enExample)
EP (1) EP1828186A1 (enExample)
JP (1) JP5111113B2 (enExample)
AU (1) AU2005316668B2 (enExample)
CA (1) CA2590294A1 (enExample)
WO (1) WO2006065703A1 (enExample)

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