JP4934309B2 - 液体口腔用組成物 - Google Patents
液体口腔用組成物 Download PDFInfo
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- JP4934309B2 JP4934309B2 JP2005304313A JP2005304313A JP4934309B2 JP 4934309 B2 JP4934309 B2 JP 4934309B2 JP 2005304313 A JP2005304313 A JP 2005304313A JP 2005304313 A JP2005304313 A JP 2005304313A JP 4934309 B2 JP4934309 B2 JP 4934309B2
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- fatty acid
- liquid oral
- oil
- acid ester
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Description
(A)油溶性香料
(B)カチオン性殺菌剤
(C)糖脂肪酸エステル
(D)ポリグリセリン脂肪酸エステル、ポリオキシエチレン硬化ヒマシ油及びソルビタン脂肪酸エステルからなる群より選ばれる1種又は2種以上
を含有する液体口腔用組成物を提供するものである。
表2中の実施例1及び実施例5は参考例であって、特許請求の範囲に包含されるものではない。
洗口液を調整後、50℃にて2週間放置したときの、液の性状を下記に示す判定基準にて評価した。
判定基準
◎:透明
○:やや透明
△:透明ではないが分離なし
×:分離
洗口液10mLで30秒間含嗽し吐き出したときに口の中に残る苦味を下記に示す判定基準にて判定した。
判定基準
◎:苦くない
○:わずかに苦い
△:やや苦い
×:かなり苦い
歯牙のモデルとしてエナメル質の主成分であるハイドロキシアパタイト(HA)粉末(太平化学産業;以下、HAと略す)を用いた。10mgのHAを表1および表2に示す各洗口液1mLに30秒間浸漬後、イオン交換水2mLにて洗浄し、HAに吸着した殺菌剤を65%アセトニトリル溶液で抽出したものを高速液体クロマトグラフィ(ODSカラム:Superspher100(関東化学製)、流速:1mL/min、測定波長:210nm)にて定量し、吸着量を算出した。
糖脂肪酸エステル:ショ糖ミリスチン酸エステル
ポリグリセリン脂肪酸エステル:ポリグリセリンミリスチン酸エステル(縮合度10)
ソルビタン脂肪酸エステル:ソルビタンステアリン酸エステル
香料:メントール+シネオール+スパイス油
Claims (5)
- 次の成分(A)、(B)、(C)及び(D)、
(A)油溶性香料 0.1〜2質量%
(B)カチオン性殺菌剤 0.001〜0.5質量%
(C)糖脂肪酸エステル 0.01〜1質量%
(D)ポリグリセリン脂肪酸エステル 0.001〜1質量%
を含有する液体口腔用組成物(ただし、ポリオキシエチレン硬化ヒマシ油を含有する場合を除く)。 - さらにエリスリトールを含有する請求項1に記載の液体口腔用組成物。
- アニオン界面活性剤が口腔用組成物中に0.01質量%以下である請求項1又は2に記載の液体口腔用組成物。
- さらにエタノールを含有する請求項1〜3のいずれか1項に記載の液体口腔用組成物。
- 成分(C)と成分(D)の含有量の質量比が30:1〜1:10である請求項1〜4のいずれか1項に記載の液体口腔用組成物。
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