JP4904055B2 - 液状乳化化粧料 - Google Patents
液状乳化化粧料 Download PDFInfo
- Publication number
- JP4904055B2 JP4904055B2 JP2005518044A JP2005518044A JP4904055B2 JP 4904055 B2 JP4904055 B2 JP 4904055B2 JP 2005518044 A JP2005518044 A JP 2005518044A JP 2005518044 A JP2005518044 A JP 2005518044A JP 4904055 B2 JP4904055 B2 JP 4904055B2
- Authority
- JP
- Japan
- Prior art keywords
- component
- liquid
- oil
- cosmetic
- emulsified cosmetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002537 cosmetic Substances 0.000 title claims description 61
- 239000007788 liquid Substances 0.000 title claims description 45
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 38
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 27
- 239000003792 electrolyte Substances 0.000 claims description 20
- -1 ascorbic acid glucoside Chemical class 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 11
- RYCNUMLMNKHWPZ-SNVBAGLBSA-N 1-acetyl-sn-glycero-3-phosphocholine Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C RYCNUMLMNKHWPZ-SNVBAGLBSA-N 0.000 claims description 10
- 229930182558 Sterol Natural products 0.000 claims description 6
- 235000003702 sterols Nutrition 0.000 claims description 6
- 150000003432 sterols Chemical class 0.000 claims description 5
- 239000004137 magnesium phosphate Substances 0.000 claims description 4
- 229960002261 magnesium phosphate Drugs 0.000 claims description 4
- 229910000157 magnesium phosphate Inorganic materials 0.000 claims description 4
- 229940024606 amino acid Drugs 0.000 claims description 3
- 150000001413 amino acids Chemical class 0.000 claims description 3
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical compound N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 claims description 3
- 229960000655 ensulizole Drugs 0.000 claims description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 2
- YRXGUZPUZBCGST-UHFFFAOYSA-N [2-(hydroxymethoxy)phenyl]-phenylmethanone Chemical compound OCOC1=CC=CC=C1C(=O)C1=CC=CC=C1 YRXGUZPUZBCGST-UHFFFAOYSA-N 0.000 claims description 2
- 239000011668 ascorbic acid Substances 0.000 claims description 2
- 229960005070 ascorbic acid Drugs 0.000 claims description 2
- 235000010323 ascorbic acid Nutrition 0.000 claims description 2
- 239000004202 carbamide Substances 0.000 claims description 2
- 229930182478 glucoside Natural products 0.000 claims description 2
- 229940074774 glycyrrhizinate Drugs 0.000 claims description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
- ODHCTXKNWHHXJC-VKHMYHEASA-M 5-oxo-L-prolinate Chemical compound [O-]C(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-M 0.000 claims 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 1
- 229940001447 lactate Drugs 0.000 claims 1
- 229940071139 pyrrolidone carboxylate Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 229940045136 urea Drugs 0.000 claims 1
- 238000003860 storage Methods 0.000 description 20
- 239000003974 emollient agent Substances 0.000 description 19
- 230000000694 effects Effects 0.000 description 18
- 239000003921 oil Substances 0.000 description 15
- 235000019198 oils Nutrition 0.000 description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- 239000006210 lotion Substances 0.000 description 10
- 239000008213 purified water Substances 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 235000014113 dietary fatty acids Nutrition 0.000 description 8
- 239000003995 emulsifying agent Substances 0.000 description 8
- 239000000194 fatty acid Substances 0.000 description 8
- 229930195729 fatty acid Natural products 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 7
- 244000068988 Glycine max Species 0.000 description 6
- 235000010469 Glycine max Nutrition 0.000 description 6
- 239000004166 Lanolin Substances 0.000 description 6
- 239000008406 cosmetic ingredient Substances 0.000 description 6
- 235000019441 ethanol Nutrition 0.000 description 6
- 238000011156 evaluation Methods 0.000 description 6
- 235000019388 lanolin Nutrition 0.000 description 6
- 229940039717 lanolin Drugs 0.000 description 6
- RUHCWQAFCGVQJX-RVWHZBQESA-N (3s,8s,9s,10r,13r,14s,17r)-3-hydroxy-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-1-one Chemical compound C1C=C2C[C@H](O)CC(=O)[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 RUHCWQAFCGVQJX-RVWHZBQESA-N 0.000 description 5
- QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 description 5
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 description 5
- 239000000839 emulsion Substances 0.000 description 5
- 230000002349 favourable effect Effects 0.000 description 5
- 235000011187 glycerol Nutrition 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 5
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 5
- 239000001540 sodium lactate Substances 0.000 description 5
- 229940005581 sodium lactate Drugs 0.000 description 5
- 235000011088 sodium lactate Nutrition 0.000 description 5
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 4
- TXBCBTDQIULDIA-UHFFFAOYSA-N 2-[[3-hydroxy-2,2-bis(hydroxymethyl)propoxy]methyl]-2-(hydroxymethyl)propane-1,3-diol Chemical compound OCC(CO)(CO)COCC(CO)(CO)CO TXBCBTDQIULDIA-UHFFFAOYSA-N 0.000 description 4
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 4
- RFMMMVDNIPUKGG-YFKPBYRVSA-N N-acetyl-L-glutamic acid Chemical compound CC(=O)N[C@H](C(O)=O)CCC(O)=O RFMMMVDNIPUKGG-YFKPBYRVSA-N 0.000 description 4
- 235000021355 Stearic acid Nutrition 0.000 description 4
- 239000002260 anti-inflammatory agent Substances 0.000 description 4
- 229940121363 anti-inflammatory agent Drugs 0.000 description 4
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 150000004665 fatty acids Chemical class 0.000 description 4
- 239000003906 humectant Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 4
- 150000003904 phospholipids Chemical class 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 description 4
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 description 4
- 239000008117 stearic acid Substances 0.000 description 4
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 3
- ULQISTXYYBZJSJ-UHFFFAOYSA-N 12-hydroxyoctadecanoic acid Chemical compound CCCCCCC(O)CCCCCCCCCCC(O)=O ULQISTXYYBZJSJ-UHFFFAOYSA-N 0.000 description 3
- 102000002322 Egg Proteins Human genes 0.000 description 3
- 108010000912 Egg Proteins Proteins 0.000 description 3
- 239000004909 Moisturizer Substances 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000003796 beauty Effects 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 235000013345 egg yolk Nutrition 0.000 description 3
- 210000002969 egg yolk Anatomy 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 125000005456 glyceride group Chemical group 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 description 3
- 230000001333 moisturizer Effects 0.000 description 3
- 239000002304 perfume Substances 0.000 description 3
- 230000002087 whitening effect Effects 0.000 description 3
- 229940058015 1,3-butylene glycol Drugs 0.000 description 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- 239000007844 bleaching agent Substances 0.000 description 2
- 235000019437 butane-1,3-diol Nutrition 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004200 microcrystalline wax Substances 0.000 description 2
- 235000019808 microcrystalline wax Nutrition 0.000 description 2
- 229940114937 microcrystalline wax Drugs 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
- 239000010466 nut oil Substances 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- UFEJXQWSRLAIOY-UHFFFAOYSA-N phenyl 1h-benzimidazole-2-sulfonate Chemical compound N=1C2=CC=CC=C2NC=1S(=O)(=O)OC1=CC=CC=C1 UFEJXQWSRLAIOY-UHFFFAOYSA-N 0.000 description 2
- XOJVVFBFDXDTEG-UHFFFAOYSA-N pristane Chemical compound CC(C)CCCC(C)CCCC(C)CCCC(C)C XOJVVFBFDXDTEG-UHFFFAOYSA-N 0.000 description 2
- 229960001153 serine Drugs 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 229940032094 squalane Drugs 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000000475 sunscreen effect Effects 0.000 description 2
- 239000000516 sunscreening agent Substances 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 description 1
- BJDAUCLANVMIOB-UHFFFAOYSA-N (3-decanoyloxy-2,2-dimethylpropyl) decanoate Chemical compound CCCCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCCCC BJDAUCLANVMIOB-UHFFFAOYSA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 description 1
- DMBUODUULYCPAK-UHFFFAOYSA-N 1,3-bis(docosanoyloxy)propan-2-yl docosanoate Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCCCC DMBUODUULYCPAK-UHFFFAOYSA-N 0.000 description 1
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 1
- 229940114069 12-hydroxystearate Drugs 0.000 description 1
- 229940114072 12-hydroxystearic acid Drugs 0.000 description 1
- DHGBAFGZLVRESL-UHFFFAOYSA-N 14-methylpentadecyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C DHGBAFGZLVRESL-UHFFFAOYSA-N 0.000 description 1
- RKJGFHYCZPZJPE-UHFFFAOYSA-N 2,2-bis(16-methylheptadecanoyloxymethyl)butyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(CC)(COC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C RKJGFHYCZPZJPE-UHFFFAOYSA-N 0.000 description 1
- XFOQWQKDSMIPHT-UHFFFAOYSA-N 2,3-dichloro-6-(trifluoromethyl)pyridine Chemical compound FC(F)(F)C1=CC=C(Cl)C(Cl)=N1 XFOQWQKDSMIPHT-UHFFFAOYSA-N 0.000 description 1
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 description 1
- FLPJVCMIKUWSDR-UHFFFAOYSA-N 2-(4-formylphenoxy)acetamide Chemical compound NC(=O)COC1=CC=C(C=O)C=C1 FLPJVCMIKUWSDR-UHFFFAOYSA-N 0.000 description 1
- GECRRQVLQHRVNH-MRCUWXFGSA-N 2-octyldodecyl (z)-octadec-9-enoate Chemical compound CCCCCCCCCCC(CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC GECRRQVLQHRVNH-MRCUWXFGSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- LAIUFBWHERIJIH-UHFFFAOYSA-N 3MC7 Natural products CCCCC(C)CC LAIUFBWHERIJIH-UHFFFAOYSA-N 0.000 description 1
- ZQXRINMCMHCYBD-UHFFFAOYSA-N 4-(2-ethylhexoxy)-4-oxobutanoic acid Chemical compound CCCCC(CC)COC(=O)CCC(O)=O ZQXRINMCMHCYBD-UHFFFAOYSA-N 0.000 description 1
- MVJSIAIXMFGVSA-UHFFFAOYSA-N 6-(2-hexyldecoxy)-6-oxohexanoic acid Chemical compound CCCCCCCCC(CCCCCC)COC(=O)CCCCC(O)=O MVJSIAIXMFGVSA-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 235000021357 Behenic acid Nutrition 0.000 description 1
- 241000283153 Cetacea Species 0.000 description 1
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 description 1
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 description 1
- SHBUUTHKGIVMJT-UHFFFAOYSA-N Hydroxystearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OO SHBUUTHKGIVMJT-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- MIJPAVRNWPDMOR-ZAFYKAAXSA-N L-ascorbic acid 2-phosphate Chemical compound OC[C@H](O)[C@H]1OC(=O)C(OP(O)(O)=O)=C1O MIJPAVRNWPDMOR-ZAFYKAAXSA-N 0.000 description 1
- 150000000996 L-ascorbic acids Chemical class 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- ACFGRWJEQJVZTM-LEJBHHMKSA-L Magnesium L-ascorbic acid-2-phosphate Chemical compound [Mg+2].OC[C@H](O)[C@H]1OC(=O)C(OP([O-])([O-])=O)=C1O ACFGRWJEQJVZTM-LEJBHHMKSA-L 0.000 description 1
- JJIHLJJYMXLCOY-UHFFFAOYSA-N N-acetyl-DL-serine Natural products CC(=O)NC(CO)C(O)=O JJIHLJJYMXLCOY-UHFFFAOYSA-N 0.000 description 1
- 241000772415 Neovison vison Species 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 102000015439 Phospholipases Human genes 0.000 description 1
- 108010064785 Phospholipases Proteins 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 235000019774 Rice Bran oil Nutrition 0.000 description 1
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 235000018936 Vitellaria paradoxa Nutrition 0.000 description 1
- 241001135917 Vitellaria paradoxa Species 0.000 description 1
- CWRILEGKIAOYKP-SSDOTTSWSA-M [(2r)-3-acetyloxy-2-hydroxypropyl] 2-aminoethyl phosphate Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCCN CWRILEGKIAOYKP-SSDOTTSWSA-M 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 229940116226 behenic acid Drugs 0.000 description 1
- HGKOWIQVWAQWDS-UHFFFAOYSA-N bis(16-methylheptadecyl) 2-hydroxybutanedioate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CC(O)C(=O)OCCCCCCCCCCCCCCCC(C)C HGKOWIQVWAQWDS-UHFFFAOYSA-N 0.000 description 1
- 239000004204 candelilla wax Substances 0.000 description 1
- 235000013868 candelilla wax Nutrition 0.000 description 1
- 229940073532 candelilla wax Drugs 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 229940074979 cetyl palmitate Drugs 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000004581 coalescence Methods 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- VJHINFRRDQUWOJ-UHFFFAOYSA-N dioctyl sebacate Chemical compound CCCCC(CC)COC(=O)CCCCCCCCC(=O)OCC(CC)CCCC VJHINFRRDQUWOJ-UHFFFAOYSA-N 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 229940100608 glycol distearate Drugs 0.000 description 1
- IUJAMGNYPWYUPM-UHFFFAOYSA-N hentriacontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC IUJAMGNYPWYUPM-UHFFFAOYSA-N 0.000 description 1
- PXDJXZJSCPSGGI-UHFFFAOYSA-N hexadecanoic acid hexadecyl ester Natural products CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC PXDJXZJSCPSGGI-UHFFFAOYSA-N 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 229940072106 hydroxystearate Drugs 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 150000003893 lactate salts Chemical class 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 235000019488 nut oil Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- BARWIPMJPCRCTP-UHFFFAOYSA-N oleic acid oleyl ester Natural products CCCCCCCCC=CCCCCCCCCOC(=O)CCCCCCCC=CCCCCCCCC BARWIPMJPCRCTP-UHFFFAOYSA-N 0.000 description 1
- BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 235000019809 paraffin wax Nutrition 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000011814 protection agent Substances 0.000 description 1
- DQAKJEWZWDQURW-UHFFFAOYSA-N pyrrolidonecarboxylic acid Chemical class OC(=O)N1CCCC1=O DQAKJEWZWDQURW-UHFFFAOYSA-N 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000008165 rice bran oil Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 229940057910 shea butter Drugs 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000002594 sorbent Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229960004274 stearic acid Drugs 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- BORJONZPSTVSFP-UHFFFAOYSA-N tetradecyl 2-hydroxypropanoate Chemical compound CCCCCCCCCCCCCCOC(=O)C(C)O BORJONZPSTVSFP-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 1
- 229940118594 trimethylolpropane triisostearate Drugs 0.000 description 1
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/21—Emulsions characterized by droplet sizes below 1 micron
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Description
(A)リゾリン脂質
(B)油 0.5〜30.0質量%
(C)電解質美容成分
(D)水
を含有する液状乳化化粧料に関するものである。また、成分(A)と成分(B)の質量比が1:10〜3:1である前記液状乳化粧料に関する。更にまた、成分(E)としてポリオキシエチレンステロールエーテルを含有する液状乳化化粧料に関する。更にまた、乳化滴の粒子径が30〜300nmである液状乳化化粧料に関するものである。更にまた成分(C)を0.1〜10質量%含有する液状乳化化粧料に関するものである。更にまた、成分(A)が、リゾホスファチジルコリンを15質量%以上含有する前記液状乳化化粧料に関する。
下記表1及び表2に示す組成の液状乳化化粧料を以下に示す製造方法により製造した。(1)使用感(みずみずしさ、べたつきのなさ)(2)エモリエント効果、(3)保存安定性、(4)乳化滴の粒子径、の評価項目について下記の方法により評価し、結果を併せて表1及び表2に示した。
A:1〜9を混合溶解する。(70℃)
B:10、11を加熱する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dをマイクロフルイダイザーで分散する。
F:Eに12を添加する。
化粧歴10年以上の女性20名をパネルとし、(1)使用感(みずみずしさ、べたつきのなさ)(2)エモリエント効果、それぞれの評価項目について基準Aにて5段階評価し、さらにその平均点から判定した。
5点:非常に良好
4点:良好
3点:普通
2点:不良
1点:非常に不良
(判定)
◎:平均点4.5点以上
○:平均点3.5点以上4.5点未満
△:平均点2.5点以上3.5点未満
×:平均点2.5点未満
経時安定性の評価方法としては、表1に示す液状乳化化粧料を40℃で保存した時の状態を目視により観察し、以下の基準Bに従い評価した。
6ヶ月で分離、クリーミングが認められない:◎
6ヶ月で分離は認められないが、若干のクリーミングが認められる:○
1ヶ月で分離、クリーミングが認められる :△
1週間で分離、クリーミングが認められる :×
表1に示す液状乳化化粧料の乳化滴の粒子径は、COULTER N−4型(BECKMAN COULTER社製)にて測定した。
(成分) (%)
(1)水素添加大豆リゾリン脂質*1 0.5
(2)POE(5)コレステロールエーテル 0.1
(3)2−エチルヘキサン酸セチル 2.0
(4)ジペンタエリトリット12−ヒドロキシ脂肪酸
/ステアリン酸/ロジン酸エステル 0.05
(5)ステアリン酸 0.05
(6)ジプロピレングリコール 2.0
(7)グリセリン 3.0
(8)精製水 10.0
(9)L−アスコルビン酸−2−リン酸マグネシウム 3.0
(10)クエン酸ナトリウム 1.0
(11)パラオキシ安息香酸メチル 適量
(12)香料 適量
(13)エチルアルコール 10.0
(14)精製水 残量
*1:リゾホスファチジルコリンの含有量が90質量%
A:1〜7を混合溶解する。(70℃)
B:8を加熱する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dを高圧ホモジナイザーで分散する。
F:Eに9〜14を添加する。
(成分) (%)
(1)水素添加卵黄リゾリン脂質*1 1.0
(2)POE(10)フィトステロールエーテル 0.2
(3)ステアロイルメチルタウリンナトリウム 0.05
(4)2−エチルヘキサン酸セチル 2.0
(5)ヒドロキシステアリン酸コレステロール 0.5
(6)プロピレングリコール 3.0
(7)グリセリン 3.0
(8)精製水 20.0
(9)乳酸ナトリウム 2.0
(10)ピロリドンカルボン酸ナトリウム 2.0
(11)パラオキシ安息香酸メチル 適量
(12)香料 適量
(13)エチルアルコール 5.0
(14)精製水 残量
*1:リゾホスファチジルコリンの含有量が30質量%
A:1〜7を混合溶解する。(70℃)
B:8を加熱する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dを高圧乳化機で分散する。
F:Eに9〜14を添加する。
(成分) (%)
(1)水素添加大豆リゾリン脂質*1 1.0
(2)水素添加大豆リン脂質 0.5
(3)POE(20)コレスタノールエーテル 0.3
(4)スクワラン 5.0
(5)マイクロクリスタリンワックス 1.0
(6)1,3−ブチレングリコール 10.0
(7)グリセリン 10.0
(8)精製水 30.0
(9)グリチルリチン酸ジカリウム 3.0
(10)pH調整剤 適量
(11)パラオキシ安息香酸メチル 適量
(12)香料 適量
(13)精製水 残量
*1:リゾホスファチジルコリンの含有量が70質量%
A:1〜7を混合溶解する。(70℃)
B:8を加熱する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dに9〜13を添加する。
(成分) (%)
(1)水素添加大豆リゾリン脂質*1 0.5
(2)POE(20)フィトステロール 0.2
(3)2−エチルヘキサン酸セチル 2.0
(4)ジメチルシクロペンタシロキサン 3.0
(5)パラメトキシケイ皮酸2−エチルヘキシル 5.0
(6)ジプロピレングリコール 10.0
(7)グリセリン 3.0
(8)カルボキシビニルポリマー 0.05
(9)精製水 30.0
(10)フェニルベンズイミダゾールスルホン酸 3.0
(11)トリエタノールアミン 1.0
(12)パラオキシ安息香酸メチル 適量
(13)香料 適量
(14)エチルアルコール 5.0
(15)精製水 残量
*1:リゾホスファチジルコリンの含有量が20質量%
A:1〜7を混合溶解する。(70℃)
B:8、9を混合する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dをマイクロフルイダイザーで分散する。
F:Eに10〜15を添加する。
(成分) (%)
(1)水素添加大豆リゾリン脂質*1 2.0
(2)POE(10)フィトスタノールエーテル 0.5
(2)流動パラフィン 10.0
(3)ジメチルシクロペンタシロキサン 5.0
(4)1,3−ブチレングリコール 10.0
(5)グリセリン 5.0
(6)精製水 30.0
(7)N−アセチル−L−グルタミン酸 0.5
(8)L−セリン 0.5
(9)パラオキシ安息香酸メチル 適量
(10)香料 適量
(11)エチルアルコール 10.0
(12)キサンタンガム 0.5
(13)精製水 残量
*1:リゾホスファチジルコリンの含有量が50質量%
A:1〜5を混合溶解する。(70℃)
B:6、12を混合する。(70℃)
C:AにBを添加し乳化する。(70℃)
D:Cを40℃まで冷却する。
E:Dに7〜11、13を添加する。
Claims (3)
- 次の成分(A)〜(E);
(A)リゾホスファチジルコリンを15質量%以上含有するリゾリン脂質 0.05〜10質量%
(B)油 0.5〜30.0質量%
(C)アミノ酸、乳酸塩、ピロリドンカルボン酸塩、尿素、グリチルリチン酸塩、L−アスコルビン酸−2−リン酸ナトリウム、L−アスコルビン酸−2−リン酸マグネシウム、アスコルビン酸グルコシド、フェニルベンズイミダゾールスルホン酸塩、及びヒドロキシメトキシベンゾフェノンスルホン酸塩から選択される一種又は二種以上の電解質美容成分 0.1〜10質量%
(D)水
(E)ポリオキシエチレン(5〜30)ステロールエーテル
を含有する液状乳化化粧料であって、
成分(E)を、成分(A)の1/10〜3/4含有する液状乳化化粧料。 - 成分(A)と成分(B)の質量比が1:10〜3:1である請求項1の液状乳化化粧料。
- 乳化滴の粒子径が30〜300nmである請求項1又は2に記載の液状乳化化粧料。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005518044A JP4904055B2 (ja) | 2004-02-18 | 2005-02-17 | 液状乳化化粧料 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004040789 | 2004-02-18 | ||
JP2004040789 | 2004-02-18 | ||
PCT/JP2005/002397 WO2005077322A1 (ja) | 2004-02-18 | 2005-02-17 | 液状乳化化粧料 |
JP2005518044A JP4904055B2 (ja) | 2004-02-18 | 2005-02-17 | 液状乳化化粧料 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2005077322A1 JPWO2005077322A1 (ja) | 2007-10-18 |
JP4904055B2 true JP4904055B2 (ja) | 2012-03-28 |
Family
ID=34857901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005518044A Active JP4904055B2 (ja) | 2004-02-18 | 2005-02-17 | 液状乳化化粧料 |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP4904055B2 (ja) |
KR (1) | KR101223302B1 (ja) |
CN (1) | CN1917850B (ja) |
HK (1) | HK1098391A1 (ja) |
TW (1) | TW200603833A (ja) |
WO (1) | WO2005077322A1 (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5437552B2 (ja) * | 2006-03-30 | 2014-03-12 | 株式会社コーセー | 2剤混合型皮膚外用剤 |
WO2009020067A1 (ja) * | 2007-08-03 | 2009-02-12 | Kose Corporation | 液状化粧料 |
JP4659810B2 (ja) * | 2007-10-26 | 2011-03-30 | 株式会社ファンケル | 乳化化粧料 |
JP5833810B2 (ja) * | 2010-03-31 | 2015-12-16 | 株式会社コーセー | 水中油型乳化化粧料 |
JP2013082643A (ja) * | 2011-10-07 | 2013-05-09 | Mikimoto Pharmaceut Co Ltd | O/w型エマルジョン |
JP6010317B2 (ja) * | 2012-03-30 | 2016-10-19 | 株式会社コーセー | アスコルビン酸誘導体が配合された水中油型乳化組成物 |
JP6114086B2 (ja) * | 2013-03-28 | 2017-04-12 | 株式会社コーセー | 化粧料 |
JP6914654B2 (ja) * | 2016-12-28 | 2021-08-04 | ライオン株式会社 | 口腔用組成物 |
KR20190075408A (ko) | 2017-12-21 | 2019-07-01 | 탑월드(주) | 천연 오일 화장료 조성물 |
KR101953559B1 (ko) * | 2018-09-03 | 2019-03-04 | 주식회사 펠리즈코스 | 수중유형 화장료 조성물 및 그 제조방법 |
JP7321015B2 (ja) * | 2019-07-12 | 2023-08-04 | 株式会社コーセー | バイセル構造体を含有する組成物 |
CN115612321B (zh) * | 2022-09-27 | 2024-01-19 | 常州君合科技股份有限公司 | 一种环保型水性锌铝防腐涂液及其制备方法 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6341411A (ja) * | 1986-08-07 | 1988-02-22 | Kyowa Hakko Kogyo Co Ltd | 皮膚外用剤 |
JPH03196833A (ja) * | 1989-12-27 | 1991-08-28 | Iwase Kosufua Kk | 親水性ゲル状組成物および水中油型乳化組成物 |
JPH06279254A (ja) * | 1992-07-15 | 1994-10-04 | Pola Chem Ind Inc | 化粧料用乳化組成物の製造方法 |
JPH1118697A (ja) * | 1997-07-09 | 1999-01-26 | Toyo Beauty Kk | 含油ゲル状組成物及び水中油型乳化組成物 |
JP2000226308A (ja) * | 1998-12-04 | 2000-08-15 | Shiseido Co Ltd | 表皮細胞におけるラミニンの産生促進剤 |
JP2001031551A (ja) * | 1999-07-15 | 2001-02-06 | Shiseido Co Ltd | 肌荒れ防止・改善用皮膚外用剤 |
JP2001039850A (ja) * | 1999-07-27 | 2001-02-13 | Shiseido Co Ltd | コラーゲンゲル収縮促進剤 |
JP2003063996A (ja) * | 2001-08-23 | 2003-03-05 | 禎秀 ▲廣▼▲崎▼ | 皮膚外用剤 |
JP2003235462A (ja) * | 2002-02-08 | 2003-08-26 | Asahi Denka Kogyo Kk | 乳化活性物質及び水中油型乳化脂 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3489703B2 (ja) * | 1995-10-23 | 2004-01-26 | 株式会社ノエビア | 微細エマルション組成物 |
JP3434115B2 (ja) * | 1996-02-29 | 2003-08-04 | 株式会社資生堂 | 乳化化粧料 |
JP2002138014A (ja) * | 2000-10-31 | 2002-05-14 | Noevir Co Ltd | 微細エマルション組成物 |
JP3731547B2 (ja) * | 2002-02-21 | 2006-01-05 | 不二製油株式会社 | 組織状蛋白及びこれを用いた加工食品の製造法 |
-
2005
- 2005-02-16 TW TW094104519A patent/TW200603833A/zh unknown
- 2005-02-17 WO PCT/JP2005/002397 patent/WO2005077322A1/ja active Application Filing
- 2005-02-17 JP JP2005518044A patent/JP4904055B2/ja active Active
- 2005-02-17 CN CN200580004705XA patent/CN1917850B/zh active Active
- 2005-02-17 KR KR1020067018930A patent/KR101223302B1/ko active IP Right Grant
-
2007
- 2007-06-06 HK HK07106035.7A patent/HK1098391A1/xx unknown
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6341411A (ja) * | 1986-08-07 | 1988-02-22 | Kyowa Hakko Kogyo Co Ltd | 皮膚外用剤 |
JPH03196833A (ja) * | 1989-12-27 | 1991-08-28 | Iwase Kosufua Kk | 親水性ゲル状組成物および水中油型乳化組成物 |
JPH06279254A (ja) * | 1992-07-15 | 1994-10-04 | Pola Chem Ind Inc | 化粧料用乳化組成物の製造方法 |
JPH1118697A (ja) * | 1997-07-09 | 1999-01-26 | Toyo Beauty Kk | 含油ゲル状組成物及び水中油型乳化組成物 |
JP2000226308A (ja) * | 1998-12-04 | 2000-08-15 | Shiseido Co Ltd | 表皮細胞におけるラミニンの産生促進剤 |
JP2001031551A (ja) * | 1999-07-15 | 2001-02-06 | Shiseido Co Ltd | 肌荒れ防止・改善用皮膚外用剤 |
JP2001039850A (ja) * | 1999-07-27 | 2001-02-13 | Shiseido Co Ltd | コラーゲンゲル収縮促進剤 |
JP2003063996A (ja) * | 2001-08-23 | 2003-03-05 | 禎秀 ▲廣▼▲崎▼ | 皮膚外用剤 |
JP2003235462A (ja) * | 2002-02-08 | 2003-08-26 | Asahi Denka Kogyo Kk | 乳化活性物質及び水中油型乳化脂 |
Also Published As
Publication number | Publication date |
---|---|
HK1098391A1 (en) | 2007-07-20 |
KR20060128008A (ko) | 2006-12-13 |
CN1917850B (zh) | 2011-04-06 |
CN1917850A (zh) | 2007-02-21 |
WO2005077322A1 (ja) | 2005-08-25 |
TW200603833A (en) | 2006-02-01 |
JPWO2005077322A1 (ja) | 2007-10-18 |
TWI348917B (ja) | 2011-09-21 |
KR101223302B1 (ko) | 2013-01-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4904055B2 (ja) | 液状乳化化粧料 | |
JP5571384B2 (ja) | 液状化粧料 | |
JP4709320B2 (ja) | O/w乳化組成物の製造方法 | |
JP5047369B2 (ja) | O/w微細エマルション外用剤の製造方法 | |
JP6281744B2 (ja) | 水中油型乳化化粧料 | |
JP4495941B2 (ja) | 水中油型乳化化粧料 | |
JP5491917B2 (ja) | 乳化化粧料 | |
JP5833810B2 (ja) | 水中油型乳化化粧料 | |
JP5260482B2 (ja) | 水中油型乳化化粧料 | |
JP2009263346A (ja) | カイネチンを含有する乳化型化粧料 | |
JP2008231087A (ja) | 皮膚外用剤 | |
JP2013010737A (ja) | リン脂質含有組成物 | |
JP6850599B2 (ja) | 水中油型乳化組成物および皮膚外用剤 | |
JP5503175B2 (ja) | クラッキングエアゾール組成物 | |
JP2006241038A (ja) | 乳化化粧料 | |
JP2007308379A (ja) | 乳化剤型の皮膚外用剤 | |
JP5437552B2 (ja) | 2剤混合型皮膚外用剤 | |
JP2003267830A (ja) | 液状化粧料 | |
JP2008088092A (ja) | 液状水中油型乳化化粧料 | |
JP5238139B2 (ja) | 液状乳化化粧料 | |
JP2007269668A (ja) | 水中油型美白化粧料 | |
JP2007269664A (ja) | 水中油型乳化化粧料 | |
JP2002145758A (ja) | 化粧料 | |
JP2007169174A (ja) | O/w型乳化組成物 | |
JP2023157265A (ja) | 乳化化粧料 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080214 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100810 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101012 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110913 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20111114 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20111213 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120106 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 4904055 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150113 Year of fee payment: 3 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |