JP4386465B2 - ヘテロアロイル誘導体 - Google Patents
ヘテロアロイル誘導体 Download PDFInfo
- Publication number
- JP4386465B2 JP4386465B2 JP51424298A JP51424298A JP4386465B2 JP 4386465 B2 JP4386465 B2 JP 4386465B2 JP 51424298 A JP51424298 A JP 51424298A JP 51424298 A JP51424298 A JP 51424298A JP 4386465 B2 JP4386465 B2 JP 4386465B2
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- haloalkoxy
- alkoxy
- groups
- haloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 CC(*)(C(*)(*)C(C1)=O)C(*)(*2CC2)C1=O Chemical compound CC(*)(C(*)(*)C(C1)=O)C(*)(*2CC2)C1=O 0.000 description 6
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19638486.9 | 1996-09-20 | ||
| DE19638486A DE19638486A1 (de) | 1996-09-20 | 1996-09-20 | Hetaroylderivate |
| PCT/EP1997/004894 WO1998012180A1 (de) | 1996-09-20 | 1997-09-09 | Hetaroylcyclohexandionderivate mit herbizider wirkung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001501924A JP2001501924A (ja) | 2001-02-13 |
| JP2001501924A5 JP2001501924A5 (enExample) | 2005-05-12 |
| JP4386465B2 true JP4386465B2 (ja) | 2009-12-16 |
Family
ID=7806281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51424298A Expired - Lifetime JP4386465B2 (ja) | 1996-09-20 | 1997-09-09 | ヘテロアロイル誘導体 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6479436B1 (enExample) |
| EP (1) | EP0931070B1 (enExample) |
| JP (1) | JP4386465B2 (enExample) |
| KR (1) | KR20010029525A (enExample) |
| CN (1) | CN1230951A (enExample) |
| AR (1) | AR008848A1 (enExample) |
| AT (1) | ATE234817T1 (enExample) |
| AU (1) | AU736395B2 (enExample) |
| BR (1) | BR9711407A (enExample) |
| CA (1) | CA2266526C (enExample) |
| DE (2) | DE19638486A1 (enExample) |
| EA (1) | EA002418B1 (enExample) |
| HU (1) | HUP9903186A3 (enExample) |
| IL (1) | IL128744A0 (enExample) |
| NZ (1) | NZ334547A (enExample) |
| PL (1) | PL332212A1 (enExample) |
| SK (1) | SK26199A3 (enExample) |
| WO (1) | WO1998012180A1 (enExample) |
| ZA (1) | ZA978452B (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042295B1 (en) * | 1997-12-22 | 2005-09-07 | Pharmacia & Upjohn Company LLC | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents |
| EP1112256B1 (de) * | 1998-09-08 | 2003-10-29 | Basf Aktiengesellschaft | Cyclohexenonchinolinoyl-derivate als herbizide mittel |
| AU2001241117A1 (en) * | 2000-04-04 | 2001-10-15 | Idemitsu Kosan Co. Ltd. | Fused-benzoyl derivatives and herbicide compositions containing the same |
| JP3930428B2 (ja) * | 2000-08-09 | 2007-06-13 | エフ.ホフマン−ラ ロシュ アーゲー | 抗炎症剤としてのキノリン誘導体 |
| MY133587A (en) | 2002-05-29 | 2007-11-30 | Glaxo Group Ltd | Aromatic sulfones and their medical use |
| US7244316B2 (en) | 2003-05-15 | 2007-07-17 | Delphi Technologies, Inc. | Methods of making gas sensors and sensors formed therefrom |
| UA91341C2 (ru) | 2004-07-15 | 2010-07-26 | Амр Текнолоджи, Інк. | Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| US7749995B2 (en) | 2006-05-11 | 2010-07-06 | Janssen Pharmaceutica Nv | 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors |
| CA2651942A1 (en) | 2006-05-11 | 2008-07-03 | Janssen Pharmaceutica N.V. | 1,2,3,4-tetrahydro-quinoline derivatives as cetp inhibitors |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| EA017648B1 (ru) | 2007-09-14 | 2013-02-28 | Орто-Макнейл-Янссен Фармасьютикалз, Инк. | 1',3'-двузамещенные-4-фенил-3,4,5,6-тетрагидро-2н,1'н-[1,4']бипириди-нил-2'-оны |
| TW200922566A (en) | 2007-09-14 | 2009-06-01 | Ortho Mcneil Janssen Pharm | 1,3 disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones |
| BRPI0816970A2 (pt) * | 2007-09-14 | 2015-03-24 | Ortho Mcneil Janssen Pharm | 1,3-dissubstituídas-4-fenil-1h-piridin-2-onas |
| CA2704436C (en) | 2007-11-14 | 2016-01-05 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| JP5547194B2 (ja) | 2008-09-02 | 2014-07-09 | ジャンセン ファーマシューティカルズ, インコーポレイテッド. | 代謝型グルタミン酸受容体の調節因子としての3−アザビシクロ[3.1.0]ヘキシル誘導体 |
| WO2010043396A1 (en) | 2008-10-16 | 2010-04-22 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
| JP5690277B2 (ja) | 2008-11-28 | 2015-03-25 | ジャンセン ファーマシューティカルズ, インコーポレイテッド. | 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体 |
| WO2010089993A1 (ja) * | 2009-02-03 | 2010-08-12 | クミアイ化学工業株式会社 | 縮合環化した2-ピリドン誘導体及び除草剤 |
| HRP20131122T1 (hr) | 2009-05-12 | 2013-12-20 | Janssen Pharmaceuticals, Inc. | Derivati 1,2,4-triazolo[4,3-a] piridina i njihova uporaba u lijeäśenju ili prevenciji neuroloških i psihijatrijskih poremeä†aja |
| JP5739415B2 (ja) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | (S)−7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンの結晶形態およびその使用 |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CN102439015B (zh) | 2009-05-12 | 2015-05-13 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物和其作为mGluR2受体的正向变构调节剂的用途 |
| CN102595902B (zh) * | 2009-05-12 | 2015-04-29 | 阿尔巴尼分子研究公司 | 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途 |
| ES2446971T3 (es) | 2009-05-12 | 2014-03-11 | Albany Molecular Research, Inc. | Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso |
| IN2012DN00352A (enExample) * | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
| EA201201322A1 (ru) | 2010-03-23 | 2013-05-30 | Басф Се | Пиридотиазины, обладающие гербицидным действием |
| BR112012023938A2 (pt) | 2010-03-23 | 2015-09-15 | Basf Se | piridina substituída da fórmula i, composto da fórmula i, composição e método para controlar vegetação indesejada |
| CN102858780A (zh) | 2010-03-23 | 2013-01-02 | 巴斯夫欧洲公司 | 具有除草作用的取代哒嗪 |
| EP2550279A1 (en) | 2010-03-23 | 2013-01-30 | Basf Se | Pyrazinothiazines having herbicidal action |
| US8809535B2 (en) | 2010-03-23 | 2014-08-19 | Basf Se | Substituted pyridines having herbicidal action |
| AR081526A1 (es) | 2010-03-23 | 2012-10-03 | Basf Se | Piridazinas sustituidas que tienen accion herbicida |
| ES2536433T3 (es) | 2010-11-08 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
| JP5852664B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
| EP2661435B1 (en) | 2010-11-08 | 2015-08-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
| EP2655381B1 (en) | 2010-12-23 | 2015-09-30 | Basf Se | Substituted pyridines having herbicidal activity |
| CN102249996B (zh) * | 2011-05-10 | 2012-11-14 | 北京法盖银科技有限公司 | 2-(喹啉-8-基)羰基-环己烷-1,3-二酮类化合物 |
| AR086894A1 (es) | 2011-06-09 | 2014-01-29 | Basf Se | Derivados de 2,2-dioxo-oxatiin[3,2-b]piridina, una composicion que los comprende y un metodo para controlar vegetacion indeseada que los emplea |
| WO2012168241A1 (en) | 2011-06-09 | 2012-12-13 | Basf Se | Substituted pyrazines having herbicidal activity |
| CA2862807A1 (en) * | 2011-11-30 | 2013-06-06 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
| BR112014029531A2 (pt) | 2012-06-01 | 2017-06-27 | Basf Se | composto de piridina, composição e método para controlar vegetação indesejada |
| CN103891748B (zh) * | 2012-12-27 | 2015-11-11 | 北京法盖银科技有限公司 | 一种除草剂组合物及其应用 |
| CN103621507B (zh) * | 2013-03-27 | 2015-10-07 | 北京法盖银科技有限公司 | 含有2-(喹啉-8-基)羰基-环己烷-1,3-二酮类化合物的除草组合物及其应用 |
| CN103155923B (zh) * | 2013-03-27 | 2015-01-07 | 北京法盖银科技有限公司 | 一种含有芳氧苯氧丙酸酯类化合物的除草剂组合物及其应用 |
| CN105246900A (zh) | 2013-05-24 | 2016-01-13 | 巴斯夫欧洲公司 | 具有除草活性的取代吡啶化合物 |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| RU2720237C2 (ru) | 2013-11-18 | 2020-04-28 | Форма Терапеутикс, Инк. | Композиции, содержащие бензопиперазин, в качестве ингибиторов бромодоменов вет |
| BR122019007990B1 (pt) | 2013-11-18 | 2021-05-04 | Forma Therapeutics, Inc | Composto, e, composição farmacêutica |
| AR099120A1 (es) | 2014-01-20 | 2016-06-29 | Bayer Cropscience Ag | Derivados de quinolina como insecticidas y acaricidas |
| PL3096790T3 (pl) | 2014-01-21 | 2020-01-31 | Janssen Pharmaceutica, N.V. | Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie |
| ME03518B (me) | 2014-01-21 | 2020-04-20 | Janssen Pharmaceutica Nv | Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena |
| US11129824B2 (en) | 2015-12-17 | 2021-09-28 | Biokine Therapeutics Ltd. | Small molecules for inhibiting chemokine activity and/or cancer cells growth |
| CN108586333A (zh) * | 2017-12-18 | 2018-09-28 | 定远县嘉禾植物保护剂有限责任公司 | 二氯喹啉草酮的合成方法 |
| CN110669016B (zh) * | 2018-09-29 | 2021-05-25 | 山东先达农化股份有限公司 | 三酮类化合物及其制备方法和应用以及一种除草剂 |
| WO2020124515A1 (zh) * | 2018-12-21 | 2020-06-25 | 东莞市东阳光农药研发有限公司 | 喹啉衍生物及其制备方法和用途 |
| CA3090315C (en) | 2019-05-15 | 2023-09-19 | Biokine Therapeutics Ltd. | 8-phenoxy-quinolinone derivatives for treating cancer, inhibiting chemokine activity and/or inducing cell death |
| US11884647B2 (en) | 2019-10-18 | 2024-01-30 | The Regents Of The University Of California | Compounds and methods for targeting pathogenic blood vessels |
| US12590298B2 (en) | 2019-10-18 | 2026-03-31 | The Regents Of The University Of California | Ex vivo tumor angiogenesis model |
| CN110835321B (zh) * | 2019-11-28 | 2020-11-24 | 东北农业大学 | 一种含有喹喔啉结构的三酮类化合物、制备方法及其应用 |
| CN113912537B (zh) * | 2021-08-27 | 2024-05-07 | 重庆化工职业学院 | 2-(喹啉-8-基)羰基-环己烷-1,3-二酮类化合物及其制备方法与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2014493B3 (es) | 1986-04-24 | 1990-07-16 | Ciba-Geigy Ag | Acil-ciclohexandionas y sus eteres de oximas con efecto herbicida y regulador del crecimiento de las plantas. |
| CA1340284C (en) * | 1987-03-19 | 1998-12-22 | Zeneca Inc. | Herbicidal substituted cyclic diones |
| IL91083A (en) | 1988-07-25 | 1993-04-04 | Ciba Geigy | Cyclohexanedione derivatives, their preparation and their use as herbicides |
| EP0563817A3 (en) * | 1992-03-31 | 1993-11-03 | Hoechst Ag | Salts of 2-benzoyl-cyclohexane diones, selective herbicidal agents, process for their preparation and their use for combatting weeds |
| WO1994004524A1 (fr) * | 1992-08-18 | 1994-03-03 | Idemitsu Kosan Co., Ltd. | Derive de cyclohexanedione |
| DE4434987A1 (de) | 1994-09-30 | 1996-04-04 | Basf Ag | 2-Aroylcyclohexandione, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Herbizide oder das Pflanzenwachstum regulierende Mittel |
| BR9609502A (pt) | 1995-06-29 | 1999-05-25 | Du Pont | Composto composição herbicida e método para controle do crescimento de vegetação indesejável |
| AU6777896A (en) | 1995-08-25 | 1997-03-19 | E.I. Du Pont De Nemours And Company | Bicyclic herbicides |
-
1996
- 1996-09-20 DE DE19638486A patent/DE19638486A1/de not_active Withdrawn
-
1997
- 1997-09-09 NZ NZ334547A patent/NZ334547A/xx unknown
- 1997-09-09 JP JP51424298A patent/JP4386465B2/ja not_active Expired - Lifetime
- 1997-09-09 CN CN97198078A patent/CN1230951A/zh active Pending
- 1997-09-09 EA EA199900273A patent/EA002418B1/ru not_active IP Right Cessation
- 1997-09-09 EP EP97941998A patent/EP0931070B1/de not_active Expired - Lifetime
- 1997-09-09 KR KR1019997002348A patent/KR20010029525A/ko not_active Withdrawn
- 1997-09-09 WO PCT/EP1997/004894 patent/WO1998012180A1/de not_active Ceased
- 1997-09-09 AT AT97941998T patent/ATE234817T1/de not_active IP Right Cessation
- 1997-09-09 HU HU9903186A patent/HUP9903186A3/hu unknown
- 1997-09-09 DE DE59709582T patent/DE59709582D1/de not_active Expired - Lifetime
- 1997-09-09 IL IL12874497A patent/IL128744A0/xx unknown
- 1997-09-09 SK SK261-99A patent/SK26199A3/sk unknown
- 1997-09-09 AU AU43833/97A patent/AU736395B2/en not_active Ceased
- 1997-09-09 US US09/254,973 patent/US6479436B1/en not_active Expired - Fee Related
- 1997-09-09 BR BR9711407A patent/BR9711407A/pt not_active Application Discontinuation
- 1997-09-09 CA CA002266526A patent/CA2266526C/en not_active Expired - Fee Related
- 1997-09-09 PL PL97332212A patent/PL332212A1/xx unknown
- 1997-09-19 ZA ZA978452A patent/ZA978452B/xx unknown
- 1997-09-22 AR ARP970104348A patent/AR008848A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE19638486A1 (de) | 1998-03-26 |
| BR9711407A (pt) | 1999-08-17 |
| HUP9903186A3 (en) | 2002-01-28 |
| ATE234817T1 (de) | 2003-04-15 |
| JP2001501924A (ja) | 2001-02-13 |
| PL332212A1 (en) | 1999-08-30 |
| CN1230951A (zh) | 1999-10-06 |
| CA2266526C (en) | 2008-11-18 |
| EP0931070A1 (de) | 1999-07-28 |
| AR008848A1 (es) | 2000-02-23 |
| CA2266526A1 (en) | 1998-03-26 |
| IL128744A0 (en) | 2000-01-31 |
| WO1998012180A1 (de) | 1998-03-26 |
| EA002418B1 (ru) | 2002-04-25 |
| EP0931070B1 (de) | 2003-03-19 |
| ZA978452B (en) | 1999-03-19 |
| US6479436B1 (en) | 2002-11-12 |
| HUP9903186A2 (hu) | 2000-02-28 |
| EA199900273A1 (ru) | 1999-12-29 |
| DE59709582D1 (de) | 2003-04-24 |
| NZ334547A (en) | 2000-09-29 |
| AU736395B2 (en) | 2001-07-26 |
| SK26199A3 (en) | 2000-03-13 |
| KR20010029525A (ko) | 2001-04-06 |
| AU4383397A (en) | 1998-04-14 |
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