HUP9903186A2 - Herbicid hatású heteroaroil-ciklohexándion-származékok, előállításuk és alkalmazásuk - Google Patents
Herbicid hatású heteroaroil-ciklohexándion-származékok, előállításuk és alkalmazásukInfo
- Publication number
- HUP9903186A2 HUP9903186A2 HU9903186A HUP9903186A HUP9903186A2 HU P9903186 A2 HUP9903186 A2 HU P9903186A2 HU 9903186 A HU9903186 A HU 9903186A HU P9903186 A HUP9903186 A HU P9903186A HU P9903186 A2 HUP9903186 A2 HU P9903186A2
- Authority
- HU
- Hungary
- Prior art keywords
- haloalkyl
- alkyl
- haloalkoxy
- alkynyl
- alkenyl
- Prior art date
Links
- OILAIQUEIWYQPH-UHFFFAOYSA-N cyclohexane-1,2-dione Chemical class O=C1CCCCC1=O OILAIQUEIWYQPH-UHFFFAOYSA-N 0.000 title 1
- 230000002363 herbicidal effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000001188 haloalkyl group Chemical group 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 4
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 4
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 3
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 3
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
- 125000005108 alkenylthio group Chemical group 0.000 abstract 2
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000005109 alkynylthio group Chemical group 0.000 abstract 2
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 2
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- -1 2,6-dioxo-cyclohexyl Chemical group 0.000 abstract 1
- 101150020251 NR13 gene Proteins 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 abstract 1
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
A heterőaril-ciklőhexándiőn-származékők (I) általánős képletében R1 és R2 jelentése hidrőgén-, halőgénatőm, nitrő-, cianő-,tiőcianátő-, hidrőxil-, merkaptő-, adőtt esetben szűbsztitűált alkil-,alkőxi-, alkil-tiő-, alkil-szűlfinil-, alkil-szűlfőnil-, fenil-,fenőxi-, fenil-tiő-, fenil-szűlfinil- vagy fenil-szűlfőnil-csőpőrt, Z jelentése adőtt esetben szűbsztitűált négytagú, telítetlen, részbenvagy teljesen telített, hárőm szén- és egy nitrőgénatőmból álló lánc, Q jelentése adőtt esetben szűbsztitűált ciklőhexán-1,3-diőn-2-il-csőpőrt. A találmány tárgyát képezik a vegyületek mezőgazdaságilagalkalmazható sói is. ŕ
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9903186A HUP9903186A3 (en) | 1996-09-20 | 1997-09-09 | Heteroaroyl cyclohexanedione derivatives with herbicidal effect, preparation and use thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19638486A DE19638486A1 (de) | 1996-09-20 | 1996-09-20 | Hetaroylderivate |
HU9903186A HUP9903186A3 (en) | 1996-09-20 | 1997-09-09 | Heteroaroyl cyclohexanedione derivatives with herbicidal effect, preparation and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9903186A2 true HUP9903186A2 (hu) | 2000-02-28 |
HUP9903186A3 HUP9903186A3 (en) | 2002-01-28 |
Family
ID=7806281
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903186A HUP9903186A3 (en) | 1996-09-20 | 1997-09-09 | Heteroaroyl cyclohexanedione derivatives with herbicidal effect, preparation and use thereof |
Country Status (19)
Country | Link |
---|---|
US (1) | US6479436B1 (hu) |
EP (1) | EP0931070B1 (hu) |
JP (1) | JP4386465B2 (hu) |
KR (1) | KR20010029525A (hu) |
CN (1) | CN1230951A (hu) |
AR (1) | AR008848A1 (hu) |
AT (1) | ATE234817T1 (hu) |
AU (1) | AU736395B2 (hu) |
BR (1) | BR9711407A (hu) |
CA (1) | CA2266526C (hu) |
DE (2) | DE19638486A1 (hu) |
EA (1) | EA002418B1 (hu) |
HU (1) | HUP9903186A3 (hu) |
IL (1) | IL128744A0 (hu) |
NZ (1) | NZ334547A (hu) |
PL (1) | PL332212A1 (hu) |
SK (1) | SK26199A3 (hu) |
WO (1) | WO1998012180A1 (hu) |
ZA (1) | ZA978452B (hu) |
Cited By (3)
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---|---|---|---|---|
US9388161B2 (en) | 2013-11-18 | 2016-07-12 | Forma Therapeutics, Inc. | Tetrahydroquinoline compositions as BET bromodomain inhibitors |
US9604960B2 (en) | 2009-05-12 | 2017-03-28 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
US11261159B2 (en) | 2019-05-15 | 2022-03-01 | Alonbio Ltd. | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0101999A3 (en) * | 1997-12-22 | 2003-06-30 | Upjohn Co | 4-hydroxyquinoline-3-carboxamides and hydrazides use of them and pharmaceutical compositions containing them |
CA2343144A1 (en) * | 1998-09-08 | 2000-03-16 | Basf Aktiengesellschaft | Cyclohexenonequinolinoyl-derivatives as herbicidal agents |
AU2001241117A1 (en) * | 2000-04-04 | 2001-10-15 | Idemitsu Kosan Co. Ltd. | Fused-benzoyl derivatives and herbicide compositions containing the same |
KR20030027016A (ko) * | 2000-08-09 | 2003-04-03 | 에프. 호프만-라 로슈 아게 | 항-염증제로서의 퀴놀린 유도체 |
AR040126A1 (es) | 2002-05-29 | 2005-03-16 | Glaxo Group Ltd | Compuesto de fenilsulfonilo, composicion farmaceutica que lo comprende y su uso para la elaboracion de un medicamento |
US7244316B2 (en) | 2003-05-15 | 2007-07-17 | Delphi Technologies, Inc. | Methods of making gas sensors and sensors formed therefrom |
MX2007000428A (es) | 2004-07-15 | 2008-03-05 | Amr Technology Inc | Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina. |
TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | 1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途 |
JP2009536953A (ja) | 2006-05-11 | 2009-10-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Cetp阻害剤としての1,2,3,4−テトラヒドロ−キノリン誘導体 |
JP2009536954A (ja) | 2006-05-11 | 2009-10-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Cetp阻害剤としての3,4−ジヒドロ−2h−ベンゾ[1,4]オキサジンおよびチアジン誘導体 |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
ES2409215T3 (es) * | 2007-09-14 | 2013-06-25 | Janssen Pharmaceuticals, Inc. | 4-fenil-1H-piridin-2-onas 1-3-disustituidas |
EA019085B1 (ru) | 2007-09-14 | 2014-01-30 | Янссен Фармасьютикалз, Инк. | 1',3-двузамещенные 4-(арил-х-фенил)-1н-пиридин-2-оны |
SI2203439T1 (sl) | 2007-09-14 | 2011-05-31 | Ortho Mcneil Janssen Pharm | 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni |
RU2492170C9 (ru) | 2007-11-14 | 2013-12-27 | Орто-Макнейл-Янссен Фармасьютикалз, Инк. | Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2 |
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CN110835321B (zh) * | 2019-11-28 | 2020-11-24 | 东北农业大学 | 一种含有喹喔啉结构的三酮类化合物、制备方法及其应用 |
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ATE52769T1 (de) | 1986-04-24 | 1990-06-15 | Ciba Geigy Ag | Acyl-cyclohexandione und deren oximaether mit herbizider und das pflanzenwachstum regulierender wirkung. |
CA1340284C (en) | 1987-03-19 | 1998-12-22 | Zeneca Inc. | Herbicidal substituted cyclic diones |
IL91083A (en) | 1988-07-25 | 1993-04-04 | Ciba Geigy | Cyclohexanedione derivatives, their preparation and their use as herbicides |
EP0563817A3 (en) | 1992-03-31 | 1993-11-03 | Hoechst Ag | Salts of 2-benzoyl-cyclohexane diones, selective herbicidal agents, process for their preparation and their use for combatting weeds |
JP3245421B2 (ja) * | 1992-08-18 | 2002-01-15 | 出光興産株式会社 | シクロヘキサンジオン誘導体 |
DE4434987A1 (de) | 1994-09-30 | 1996-04-04 | Basf Ag | 2-Aroylcyclohexandione, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Herbizide oder das Pflanzenwachstum regulierende Mittel |
KR19990028478A (ko) * | 1995-06-29 | 1999-04-15 | 미리암 디. 메코너헤이 | 제초제 케탈 및 스피로사이클 |
EP0846112A1 (en) | 1995-08-25 | 1998-06-10 | E.I. Du Pont De Nemours And Company | Bicyclic herbicides |
-
1996
- 1996-09-20 DE DE19638486A patent/DE19638486A1/de not_active Withdrawn
-
1997
- 1997-09-09 KR KR1019997002348A patent/KR20010029525A/ko not_active Application Discontinuation
- 1997-09-09 EP EP97941998A patent/EP0931070B1/de not_active Expired - Lifetime
- 1997-09-09 PL PL97332212A patent/PL332212A1/xx unknown
- 1997-09-09 US US09/254,973 patent/US6479436B1/en not_active Expired - Fee Related
- 1997-09-09 BR BR9711407A patent/BR9711407A/pt not_active Application Discontinuation
- 1997-09-09 JP JP51424298A patent/JP4386465B2/ja not_active Expired - Lifetime
- 1997-09-09 CA CA002266526A patent/CA2266526C/en not_active Expired - Fee Related
- 1997-09-09 AT AT97941998T patent/ATE234817T1/de not_active IP Right Cessation
- 1997-09-09 CN CN97198078A patent/CN1230951A/zh active Pending
- 1997-09-09 NZ NZ334547A patent/NZ334547A/xx unknown
- 1997-09-09 AU AU43833/97A patent/AU736395B2/en not_active Ceased
- 1997-09-09 WO PCT/EP1997/004894 patent/WO1998012180A1/de active IP Right Grant
- 1997-09-09 SK SK261-99A patent/SK26199A3/sk unknown
- 1997-09-09 IL IL12874497A patent/IL128744A0/xx unknown
- 1997-09-09 EA EA199900273A patent/EA002418B1/ru not_active IP Right Cessation
- 1997-09-09 HU HU9903186A patent/HUP9903186A3/hu unknown
- 1997-09-09 DE DE59709582T patent/DE59709582D1/de not_active Expired - Lifetime
- 1997-09-19 ZA ZA978452A patent/ZA978452B/xx unknown
- 1997-09-22 AR ARP970104348A patent/AR008848A1/es unknown
Cited By (7)
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US9604960B2 (en) | 2009-05-12 | 2017-03-28 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
US9388161B2 (en) | 2013-11-18 | 2016-07-12 | Forma Therapeutics, Inc. | Tetrahydroquinoline compositions as BET bromodomain inhibitors |
US10336722B2 (en) | 2013-11-18 | 2019-07-02 | Forma Therapeutics, Inc. | Tetrahydroquinoline compositions as BET bromodomain inhibitors |
US10611750B2 (en) | 2013-11-18 | 2020-04-07 | Forma Therapeutics, Inc. | Tetrahydroquinoline compositions as bet bromodomain inhibitors |
US11111229B2 (en) | 2013-11-18 | 2021-09-07 | Forma Therapeutics, Inc. | Tetrahydroquinoline compositions as BET bromodomain inhibitors |
US11261159B2 (en) | 2019-05-15 | 2022-03-01 | Alonbio Ltd. | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death |
US11780814B2 (en) | 2019-05-15 | 2023-10-10 | Alonbio Ltd. | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death |
Also Published As
Publication number | Publication date |
---|---|
IL128744A0 (en) | 2000-01-31 |
DE59709582D1 (de) | 2003-04-24 |
WO1998012180A1 (de) | 1998-03-26 |
KR20010029525A (ko) | 2001-04-06 |
SK26199A3 (en) | 2000-03-13 |
ATE234817T1 (de) | 2003-04-15 |
EP0931070A1 (de) | 1999-07-28 |
CN1230951A (zh) | 1999-10-06 |
HUP9903186A3 (en) | 2002-01-28 |
AR008848A1 (es) | 2000-02-23 |
CA2266526A1 (en) | 1998-03-26 |
JP4386465B2 (ja) | 2009-12-16 |
CA2266526C (en) | 2008-11-18 |
PL332212A1 (en) | 1999-08-30 |
ZA978452B (en) | 1999-03-19 |
EA199900273A1 (ru) | 1999-12-29 |
EA002418B1 (ru) | 2002-04-25 |
NZ334547A (en) | 2000-09-29 |
JP2001501924A (ja) | 2001-02-13 |
BR9711407A (pt) | 1999-08-17 |
AU4383397A (en) | 1998-04-14 |
DE19638486A1 (de) | 1998-03-26 |
EP0931070B1 (de) | 2003-03-19 |
AU736395B2 (en) | 2001-07-26 |
US6479436B1 (en) | 2002-11-12 |
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