JP4183507B2 - 神経系の損傷後疾患の処置のためのトリペプチド及びトリペプチド誘導体 - Google Patents
神経系の損傷後疾患の処置のためのトリペプチド及びトリペプチド誘導体 Download PDFInfo
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10105038A DE10105038B4 (de) | 2001-02-05 | 2001-02-05 | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
| PCT/EP2002/001183 WO2002062373A2 (en) | 2001-02-05 | 2002-02-05 | Tripeptides and tripeptide derivatives for the treatment of postlesional diseases of the nervous system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004526702A JP2004526702A (ja) | 2004-09-02 |
| JP2004526702A5 JP2004526702A5 (cg-RX-API-DMAC7.html) | 2005-12-22 |
| JP4183507B2 true JP4183507B2 (ja) | 2008-11-19 |
Family
ID=7672831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002562379A Expired - Fee Related JP4183507B2 (ja) | 2001-02-05 | 2002-02-05 | 神経系の損傷後疾患の処置のためのトリペプチド及びトリペプチド誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7122524B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1363656B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4183507B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE285244T1 (cg-RX-API-DMAC7.html) |
| DE (2) | DE10105038B4 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2230480T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1363656E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002062373A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10105038B4 (de) | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
| DE10105041A1 (de) | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| DE10105040A1 (de) | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
| JP2011201923A (ja) * | 2005-07-01 | 2011-10-13 | Snow Brand Milk Products Co Ltd | ジペプチジルペプチダーゼｉｖ阻害剤 |
| CN106317177A (zh) * | 2015-06-23 | 2017-01-11 | 首都医科大学 | Gly-Phe-Pro,其合成,活性和应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1323301C (en) * | 1987-06-05 | 1993-10-19 | Alan I. Faden | Thyrotropin-releasing hormone analogs in cns injury |
| FR2622581B1 (fr) * | 1987-11-03 | 1990-02-16 | Inorgan Sa Rech Develop Pharm | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
| EP0445606B1 (en) * | 1990-02-27 | 1997-01-22 | The Agency of Industrial Science and Technology | Novel oligopeptides, pharmaceutical composition and food containing the same, and use of oligopeptides |
| DE4007869A1 (de) | 1990-03-13 | 1991-09-19 | Merck Patent Gmbh | Aminosaeurederivate |
| JPH045240A (ja) | 1990-04-20 | 1992-01-09 | Taisho Pharmaceut Co Ltd | 抗痴呆剤 |
| US5091391A (en) * | 1990-08-16 | 1992-02-25 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of resisting neurodegenerative disorders |
| JPH06504061A (ja) | 1990-12-28 | 1994-05-12 | コーテックス ファーマシューティカルズ インコーポレイテッド | 神経変性の治療および予防におけるカルパイン阻害剤の使用 |
| WO1992013549A1 (en) * | 1991-02-07 | 1992-08-20 | Research Corporation Technologies, Inc. | Inhibition of cell proliferation by hydrophobic peptides |
| US6235929B1 (en) | 1991-12-27 | 2001-05-22 | Georgia Tech Research Corporation | Tripeptide α-ketoamides |
| ZA95260B (en) * | 1994-01-13 | 1995-09-28 | Univ Columbia | Synthetic receptors libraries and uses thereof |
| US5716929A (en) | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| JPH0940577A (ja) * | 1995-05-24 | 1997-02-10 | Mitsui Toatsu Chem Inc | トリペプチド、ジペプチドを含有する医薬組成物 |
| EP0840614A1 (en) | 1995-06-13 | 1998-05-13 | Sanofi Winthrop, Inc. | Calpain inhibitors for the treatment of neurodegenerative diseases |
| JPH09169797A (ja) * | 1995-12-22 | 1997-06-30 | Mitsui Toatsu Chem Inc | プロテアーゼアクティベーター活性を有するペプチド |
| US5840838A (en) * | 1996-02-29 | 1998-11-24 | University Of Kentucky Research Foundation | Process for enhancing the activity of amyloid β peptides |
| JP2001501930A (ja) * | 1996-10-04 | 2001-02-13 | オークランド ユニサーヴィスィズ リミテッド | 神経酵素の調節 |
| JP4727770B2 (ja) | 1997-09-26 | 2011-07-20 | カルピス株式会社 | 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤 |
| US6080848A (en) * | 1998-05-01 | 2000-06-27 | Incyte Pharmaceuticals, Inc. | Human brain associated protein |
| US6379691B1 (en) * | 1998-09-29 | 2002-04-30 | Medtronic/Ave, Inc. | Uses for medical devices having a lubricious, nitric oxide-releasing coating |
| AU1574701A (en) * | 1999-10-22 | 2001-04-30 | Wrair Walter Reed Army Institute Of Research | A pharmaceutical composition containing pglu-glu-pro-nh2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| JP4633876B2 (ja) | 1999-11-11 | 2011-02-16 | カルピス株式会社 | トリペプチドの製造方法 |
| WO2001068114A1 (en) | 2000-03-10 | 2001-09-20 | Monsanto Company | Novel peptides with anti-hypertensive activity |
| DE10105041A1 (de) | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| DE10105038B4 (de) | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
| US6846641B2 (en) * | 2002-04-23 | 2005-01-25 | Agy Therapeutics, Inc. | In vitro ischemia model |
-
2001
- 2001-02-05 DE DE10105038A patent/DE10105038B4/de not_active Expired - Fee Related
-
2002
- 2002-02-05 PT PT02719767T patent/PT1363656E/pt unknown
- 2002-02-05 EP EP02719767A patent/EP1363656B1/en not_active Expired - Lifetime
- 2002-02-05 JP JP2002562379A patent/JP4183507B2/ja not_active Expired - Fee Related
- 2002-02-05 WO PCT/EP2002/001183 patent/WO2002062373A2/en not_active Ceased
- 2002-02-05 ES ES02719767T patent/ES2230480T3/es not_active Expired - Lifetime
- 2002-02-05 AT AT02719767T patent/ATE285244T1/de not_active IP Right Cessation
- 2002-02-05 DE DE60202356T patent/DE60202356T2/de not_active Expired - Lifetime
-
2003
- 2003-08-05 US US10/635,805 patent/US7122524B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004526702A (ja) | 2004-09-02 |
| ES2230480T3 (es) | 2005-05-01 |
| DE10105038A1 (de) | 2002-08-14 |
| US7122524B2 (en) | 2006-10-17 |
| US20050080016A1 (en) | 2005-04-14 |
| DE60202356T2 (de) | 2005-12-08 |
| DE60202356D1 (de) | 2005-01-27 |
| WO2002062373A3 (en) | 2002-11-14 |
| PT1363656E (pt) | 2005-03-31 |
| EP1363656B1 (en) | 2004-12-22 |
| ATE285244T1 (de) | 2005-01-15 |
| WO2002062373A2 (en) | 2002-08-15 |
| DE10105038B4 (de) | 2005-07-07 |
| EP1363656A2 (en) | 2003-11-26 |
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