DE60202356D1 - Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems - Google Patents

Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems

Info

Publication number
DE60202356D1
DE60202356D1 DE60202356T DE60202356T DE60202356D1 DE 60202356 D1 DE60202356 D1 DE 60202356D1 DE 60202356 T DE60202356 T DE 60202356T DE 60202356 T DE60202356 T DE 60202356T DE 60202356 D1 DE60202356 D1 DE 60202356D1
Authority
DE
Germany
Prior art keywords
sub
alkyl
alkoxy
treatment
tripeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60202356T
Other languages
English (en)
Other versions
DE60202356T2 (de
Inventor
Jean Rapin
Klaus Witzmann
Jean-Marie Grumel
Jacques Gonella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NEUROTELL AG HERGISWIL
Original Assignee
NEUROTELL AG HERGISWIL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NEUROTELL AG HERGISWIL filed Critical NEUROTELL AG HERGISWIL
Priority to DE60202356T priority Critical patent/DE60202356T2/de
Application granted granted Critical
Publication of DE60202356D1 publication Critical patent/DE60202356D1/de
Publication of DE60202356T2 publication Critical patent/DE60202356T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60202356T 2001-02-05 2002-02-05 Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems Expired - Lifetime DE60202356T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60202356T DE60202356T2 (de) 2001-02-05 2002-02-05 Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10105038A DE10105038B4 (de) 2001-02-05 2001-02-05 Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE10105038 2001-02-05
DE60202356T DE60202356T2 (de) 2001-02-05 2002-02-05 Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems
PCT/EP2002/001183 WO2002062373A2 (en) 2001-02-05 2002-02-05 Tripeptides and tripeptide derivatives for the treatment of postlesional diseases of the nervous system

Publications (2)

Publication Number Publication Date
DE60202356D1 true DE60202356D1 (de) 2005-01-27
DE60202356T2 DE60202356T2 (de) 2005-12-08

Family

ID=7672831

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10105038A Expired - Fee Related DE10105038B4 (de) 2001-02-05 2001-02-05 Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE60202356T Expired - Lifetime DE60202356T2 (de) 2001-02-05 2002-02-05 Tripeptide und deren derivate zur behandlung von postläsionalen krankheiten des nervensystems

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10105038A Expired - Fee Related DE10105038B4 (de) 2001-02-05 2001-02-05 Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems

Country Status (8)

Country Link
US (1) US7122524B2 (de)
EP (1) EP1363656B1 (de)
JP (1) JP4183507B2 (de)
AT (1) ATE285244T1 (de)
DE (2) DE10105038B4 (de)
ES (1) ES2230480T3 (de)
PT (1) PT1363656E (de)
WO (1) WO2002062373A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10105040A1 (de) * 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE10105041A1 (de) 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten
DE10105038B4 (de) 2001-02-05 2005-07-07 Neurotell Ag Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
JP2011201923A (ja) * 2005-07-01 2011-10-13 Snow Brand Milk Products Co Ltd ジペプチジルペプチダーゼｉｖ阻害剤
CN106317177A (zh) * 2015-06-23 2017-01-11 首都医科大学 Gly-Phe-Pro,其合成,活性和应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1323301C (en) * 1987-06-05 1993-10-19 Alan I. Faden Thyrotropin-releasing hormone analogs in cns injury
FR2622581B1 (fr) * 1987-11-03 1990-02-16 Inorgan Sa Rech Develop Pharm Nouveaux derives de l-proline, leur preparation et leurs applications biologiques
DE69124274T2 (de) * 1990-02-27 1997-08-14 Agency Ind Science Techn Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden
DE4007869A1 (de) 1990-03-13 1991-09-19 Merck Patent Gmbh Aminosaeurederivate
JPH045240A (ja) 1990-04-20 1992-01-09 Taisho Pharmaceut Co Ltd 抗痴呆剤
US5091391A (en) * 1990-08-16 1992-02-25 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of resisting neurodegenerative disorders
AU667463B2 (en) 1990-12-28 1996-03-28 Cortex Pharmaceuticals, Inc. Use of calpain inhibitors in the inhibition and treatment of neurodegeneration
WO1992013549A1 (en) * 1991-02-07 1992-08-20 Research Corporation Technologies, Inc. Inhibition of cell proliferation by hydrophobic peptides
US6235929B1 (en) * 1991-12-27 2001-05-22 Georgia Tech Research Corporation Tripeptide α-ketoamides
ZA95260B (en) * 1994-01-13 1995-09-28 Univ Columbia Synthetic receptors libraries and uses thereof
US5716929A (en) * 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
JPH0940577A (ja) * 1995-05-24 1997-02-10 Mitsui Toatsu Chem Inc トリペプチド、ジペプチドを含有する医薬組成物
EP0840614A1 (de) 1995-06-13 1998-05-13 Sanofi Winthrop, Inc. Calpain inhibitoren für die behandlung von neurodegenerativen erkrankungen
JPH09169797A (ja) * 1995-12-22 1997-06-30 Mitsui Toatsu Chem Inc プロテアーゼアクティベーター活性を有するペプチド
US5840838A (en) * 1996-02-29 1998-11-24 University Of Kentucky Research Foundation Process for enhancing the activity of amyloid β peptides
AU743412B2 (en) * 1996-10-04 2002-01-24 Neuren Pharmaceuticals Limited Regulation of neural enzymes
JP4727770B2 (ja) 1997-09-26 2011-07-20 カルピス株式会社 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤
US6080848A (en) * 1998-05-01 2000-06-27 Incyte Pharmaceuticals, Inc. Human brain associated protein
US6379691B1 (en) * 1998-09-29 2002-04-30 Medtronic/Ave, Inc. Uses for medical devices having a lubricious, nitric oxide-releasing coating
WO2001028578A2 (en) * 1999-10-22 2001-04-26 Wrair A PHARMACEUTICAL COMPOSITION CONTAINING pGLU-GLU-PRO-NH2 AND METHOD FOR TREATING DISEASES AND INJURIES TO THE BRAIN, SPINAL CORD AND RETINA USING SAME
JP4633876B2 (ja) 1999-11-11 2011-02-16 カルピス株式会社 トリペプチドの製造方法
WO2001068114A1 (en) 2000-03-10 2001-09-20 Monsanto Company Novel peptides with anti-hypertensive activity
DE10105041A1 (de) 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten
DE10105038B4 (de) 2001-02-05 2005-07-07 Neurotell Ag Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
US6846641B2 (en) * 2002-04-23 2005-01-25 Agy Therapeutics, Inc. In vitro ischemia model

Also Published As

Publication number Publication date
EP1363656B1 (de) 2004-12-22
JP4183507B2 (ja) 2008-11-19
DE10105038B4 (de) 2005-07-07
EP1363656A2 (de) 2003-11-26
JP2004526702A (ja) 2004-09-02
ES2230480T3 (es) 2005-05-01
US20050080016A1 (en) 2005-04-14
WO2002062373A3 (en) 2002-11-14
DE60202356T2 (de) 2005-12-08
ATE285244T1 (de) 2005-01-15
US7122524B2 (en) 2006-10-17
PT1363656E (pt) 2005-03-31
DE10105038A1 (de) 2002-08-14
WO2002062373A2 (en) 2002-08-15

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