JP3786970B2 - オリゴヌクレオチド抗体複合体による抗原の検出 - Google Patents
オリゴヌクレオチド抗体複合体による抗原の検出 Download PDFInfo
- Publication number
- JP3786970B2 JP3786970B2 JP52057298A JP52057298A JP3786970B2 JP 3786970 B2 JP3786970 B2 JP 3786970B2 JP 52057298 A JP52057298 A JP 52057298A JP 52057298 A JP52057298 A JP 52057298A JP 3786970 B2 JP3786970 B2 JP 3786970B2
- Authority
- JP
- Japan
- Prior art keywords
- labeled
- antibody
- polynucleotide
- oligonucleotide
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/738,641 | 1996-10-29 | ||
| US08/738,641 US6117631A (en) | 1996-10-29 | 1996-10-29 | Detection of antigens via oligonucleotide antibody conjugates |
| PCT/US1997/019093 WO1998018488A1 (en) | 1996-10-29 | 1997-10-22 | Detection of antigens via oligonucleotide antibody conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001503517A JP2001503517A (ja) | 2001-03-13 |
| JP2001503517A5 JP2001503517A5 (https=) | 2005-05-12 |
| JP3786970B2 true JP3786970B2 (ja) | 2006-06-21 |
Family
ID=24968855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52057298A Expired - Lifetime JP3786970B2 (ja) | 1996-10-29 | 1997-10-22 | オリゴヌクレオチド抗体複合体による抗原の検出 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6117631A (https=) |
| EP (1) | EP0951297B1 (https=) |
| JP (1) | JP3786970B2 (https=) |
| AT (1) | ATE320819T1 (https=) |
| AU (1) | AU718804B2 (https=) |
| CA (1) | CA2270227C (https=) |
| DE (1) | DE69735532T2 (https=) |
| ES (1) | ES2260787T3 (https=) |
| WO (1) | WO1998018488A1 (https=) |
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|---|---|---|---|---|
| US5175270A (en) * | 1986-09-10 | 1992-12-29 | Polyprobe, Inc. | Reagents for detecting and assaying nucleic acid sequences |
| US5656731A (en) * | 1987-10-15 | 1997-08-12 | Chiron Corporation | Nucleic acid-amplified immunoassay probes |
| WO1994019693A1 (en) * | 1993-02-24 | 1994-09-01 | Baxter Diagnostics Inc. | Immobilization of specific binding assay reagents |
| US6121056A (en) * | 1993-02-24 | 2000-09-19 | Dade Behring Inc. | Random detection of antigens with antibodies immobilized on soluble submicron particles |
| AU6913394A (en) * | 1993-05-13 | 1994-12-12 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acid tagged immunoassay |
| US5635602A (en) * | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
| US5912332A (en) * | 1996-07-26 | 1999-06-15 | Hybridon, Inc. | Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides |
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| WO1998018488A1 (en) | 1998-05-07 |
| EP0951297B1 (en) | 2006-03-22 |
| DE69735532T2 (de) | 2006-11-23 |
| JP2001503517A (ja) | 2001-03-13 |
| ATE320819T1 (de) | 2006-04-15 |
| ES2260787T3 (es) | 2006-11-01 |
| US6110687A (en) | 2000-08-29 |
| DE69735532D1 (de) | 2006-05-11 |
| EP0951297A4 (en) | 2002-01-02 |
| CA2270227A1 (en) | 1998-05-07 |
| AU4914097A (en) | 1998-05-22 |
| AU718804B2 (en) | 2000-04-20 |
| CA2270227C (en) | 2005-02-08 |
| US6117631A (en) | 2000-09-12 |
| EP0951297A1 (en) | 1999-10-27 |
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