JP3359630B2 - 長時間活性を有するニコチン膏薬 - Google Patents

長時間活性を有するニコチン膏薬

Info

Publication number
JP3359630B2
JP3359630B2 JP25369089A JP25369089A JP3359630B2 JP 3359630 B2 JP3359630 B2 JP 3359630B2 JP 25369089 A JP25369089 A JP 25369089A JP 25369089 A JP25369089 A JP 25369089A JP 3359630 B2 JP3359630 B2 JP 3359630B2
Authority
JP
Japan
Prior art keywords
nicotine
plaster
skin
layer
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP25369089A
Other languages
English (en)
Japanese (ja)
Other versions
JPH02174714A (ja
Inventor
ダブリュー ベイカー リチャード
コッチンク フランク
ワン カール
Original Assignee
ファルマシア アンド アップジョン アクチェボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ファルマシア アンド アップジョン アクチェボラーグ filed Critical ファルマシア アンド アップジョン アクチェボラーグ
Publication of JPH02174714A publication Critical patent/JPH02174714A/ja
Application granted granted Critical
Publication of JP3359630B2 publication Critical patent/JP3359630B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
JP25369089A 1988-10-28 1989-09-28 長時間活性を有するニコチン膏薬 Expired - Lifetime JP3359630B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/264,397 US4943435A (en) 1987-10-05 1988-10-28 Prolonged activity nicotine patch
US264397 1988-10-28

Publications (2)

Publication Number Publication Date
JPH02174714A JPH02174714A (ja) 1990-07-06
JP3359630B2 true JP3359630B2 (ja) 2002-12-24

Family

ID=23005890

Family Applications (1)

Application Number Title Priority Date Filing Date
JP25369089A Expired - Lifetime JP3359630B2 (ja) 1988-10-28 1989-09-28 長時間活性を有するニコチン膏薬

Country Status (13)

Country Link
US (1) US4943435A (de)
EP (2) EP0916339B1 (de)
JP (1) JP3359630B2 (de)
AT (2) ATE177651T1 (de)
AU (1) AU635714B2 (de)
CA (1) CA1338009C (de)
DE (2) DE68929533T2 (de)
DK (1) DK175328B1 (de)
ES (2) ES2241083T3 (de)
GR (1) GR3030041T3 (de)
MX (1) MX165947B (de)
NO (1) NO301216B1 (de)
NZ (1) NZ230554A (de)

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JPH02174714A (ja) 1990-07-06
EP0916339B1 (de) 2005-04-13
ES2241083T3 (es) 2005-10-16
DE68929533T2 (de) 2006-03-09
EP0366240B1 (de) 1999-03-17
GR3030041T3 (en) 1999-07-30
DK175328B1 (da) 2004-08-23
CA1338009C (en) 1996-01-30
EP0916339A1 (de) 1999-05-19
US4943435A (en) 1990-07-24
AU4105789A (en) 1990-05-03
EP0366240A1 (de) 1990-05-02
NO893570D0 (no) 1989-09-05
DE68929533D1 (de) 2005-05-19
ATE177651T1 (de) 1999-04-15
NO893570L (no) 1990-04-30
ATE292968T1 (de) 2005-04-15
NZ230554A (en) 1991-02-26
DE68928952T2 (de) 1999-08-26
DK434189A (da) 1990-04-29
DE68928952D1 (de) 1999-04-22
DK434189D0 (da) 1989-09-01
MX165947B (es) 1992-12-09
ES2129387T3 (es) 1999-06-16
NO301216B1 (no) 1997-09-29
AU635714B2 (en) 1993-04-01

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