|
FR104E
(enExample)
|
|
|
|
|
|
US5843708A
(en)
|
1988-01-05 |
1998-12-01 |
Ciba-Geigy Corporation |
Chimeric antibodies
|
|
FI903489A7
(fi)
|
1988-11-11 |
1990-07-10 |
Medical Res Council |
Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
US5397703A
(en)
|
1992-07-09 |
1995-03-14 |
Cetus Oncology Corporation |
Method for generation of antibodies to cell surface molecules
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
|
US6946129B1
(en)
|
1999-06-08 |
2005-09-20 |
Seattle Genetics, Inc. |
Recombinant anti-CD40 antibody and uses thereof
|
|
DE19939653A1
(de)
|
1999-08-13 |
2001-02-22 |
Thomas Huenig |
Verwendung CD28 spezifischer monoklonaler Antikörper zur Herstellung einer pharmazeutischen Zusammensetzung
|
|
JP4210454B2
(ja)
|
2001-03-27 |
2009-01-21 |
日本たばこ産業株式会社 |
炎症性腸疾患治療剤
|
|
JP3871503B2
(ja)
|
1999-08-30 |
2007-01-24 |
日本たばこ産業株式会社 |
免疫性疾患治療剤
|
|
DE60035057T2
(de)
|
1999-10-04 |
2008-01-31 |
Novartis Vaccines and Diagnostics, Inc., Emeryville |
CD40 Antagonist zur Behandlung von Psoriasis
|
|
AU2001233027A1
(en)
|
2000-01-27 |
2001-08-07 |
Genetics Institute, Llc |
Antibodies against ctla4 (cd152), conjugates comprising same, and uses thereof
|
|
CA2406961A1
(en)
|
2000-04-19 |
2002-02-14 |
Tanox, Inc. |
Cd40 antagonists for use in treating psoriasis and other inflammatory skin conditions
|
|
US20030059427A1
(en)
|
2000-04-28 |
2003-03-27 |
Force Walker R. |
Isolation and characterization of highly active anti-CD40 antibody
|
|
JP3597140B2
(ja)
|
2000-05-18 |
2004-12-02 |
日本たばこ産業株式会社 |
副刺激伝達分子ａｉｌｉｍに対するヒトモノクローナル抗体及びその医薬用途
|
|
WO2002028481A2
(en)
|
2000-10-02 |
2002-04-11 |
Chiron Corporation |
Methods of therapy for b-cell malignancies using antagonist anti-cd40 antibodies
|
|
DE10050935A1
(de)
|
2000-10-11 |
2002-05-02 |
Tegenero Gmbh |
Verwendung CD28 spezifischer monoklonaler Antikörper zur Stimulation von Blutzellen, welche kein CD28 tragen
|
|
US8501471B2
(en)
|
2000-10-18 |
2013-08-06 |
Sloan-Kettering Institute For Cancer Research |
Uses of monoclonal antibody 8H9
|
|
US20020102264A1
(en)
|
2000-10-18 |
2002-08-01 |
Cheung Nai-Kong V. |
Uses of monoclonal antibody 8H9
|
|
US8414892B2
(en)
|
2000-10-18 |
2013-04-09 |
Sloan-Kettering Institute For Cancer Research |
Uses of monoclonal antibody 8H9
|
|
WO2002032375A2
(en)
|
2000-10-18 |
2002-04-25 |
Sloan-Kettering Institute For Cancer Research |
Uses of monoclonal antibody 8h9
|
|
NZ526569A
(en)
|
2000-12-14 |
2005-07-29 |
Fujisawa Pharmaceutical Co |
Silenced anti-CD28 antibodies and use thereof for inducing T-cell tolerance, providing immunosupression and treating organ or tissue transplant rejection
|
|
EP1345969B1
(fr)
|
2000-12-26 |
2010-08-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Anticorps anti-cd28
|
|
AR036993A1
(es)
|
2001-04-02 |
2004-10-20 |
Wyeth Corp |
Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
|
|
CA2658221C
(en)
|
2001-04-27 |
2012-11-27 |
Kyowa Kirin Co., Ltd. |
Anti-cd40 monoclonal antibody
|
|
WO2003029296A1
(en)
|
2001-10-02 |
2003-04-10 |
Chiron Corporation |
Human anti-cd40 antibodies
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
AU2002346581A1
(en)
|
2001-11-26 |
2003-06-10 |
Chiron Corporation |
Antagonist anti-cd40 monoclonal antibody therapy for multiple sclerosis treatment
|
|
US20080199471A1
(en)
|
2002-03-01 |
2008-08-21 |
Bernett Matthew J |
Optimized cd40 antibodies and methods of using the same
|
|
AU2003220079A1
(en)
|
2002-03-08 |
2003-09-22 |
Sloan-Kettering Institute For Cancer Research |
Uses of monoclonal antibody 8h9
|
|
DE10212108A1
(de)
|
2002-03-13 |
2003-10-02 |
Tegenero Ag |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung
|
|
ES2295639T3
(es)
|
2002-06-13 |
2008-04-16 |
Crucell Holland B.V. |
Agonistas del receptor ox40=(=cd134) y uso terapeutico descripcion.
|
|
DE10230223A1
(de)
|
2002-07-04 |
2004-01-22 |
Tegenero Ag |
Mikropartikel mit CD28-spezifischen monoklonalen Antikörpern
|
|
US7052694B2
(en)
|
2002-07-16 |
2006-05-30 |
Mayo Foundation For Medical Education And Research |
Dendritic cell potentiation
|
|
US6693136B1
(en)
|
2002-07-26 |
2004-02-17 |
Abbott Laboratories |
Fluorenes and anthracenes that inhibit P2X3 and P2X2/3 containing receptors
|
|
JP2006500921A
(ja)
|
2002-07-30 |
2006-01-12 |
ブリストル−マイヤーズ スクイブ カンパニー |
ヒト４−１ｂｂに対するヒト化抗体
|
|
US7291331B1
(en)
|
2002-09-11 |
2007-11-06 |
La Jolla Institute For Allergy And Immunology |
Methods of treating OX40 medicated recall immune responses
|
|
ES2367430T3
(es)
|
2002-12-23 |
2011-11-03 |
Wyeth Llc |
Anticuerpos contra pd-1 y sus usos.
|
|
US20070104688A1
(en)
|
2003-02-13 |
2007-05-10 |
City Of Hope |
Small interfering RNA mediated transcriptional gene silencing in mammalian cells
|
|
AU2004244626A1
(en)
|
2003-05-23 |
2004-12-09 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
GITR ligand and GITR ligand-related molecules and antibodies and uses thereof
|
|
US20090191213A9
(en)
|
2003-07-02 |
2009-07-30 |
Novo Nordisk A/S |
Compositions and methods for regulating NK cell activity
|
|
EP1600164A3
(de)
|
2003-09-22 |
2006-05-17 |
TeGenero AG |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer Pharmazeutischen Zusammensetzung mit dosisabhängiger Wirkung
|
|
US7288638B2
(en)
|
2003-10-10 |
2007-10-30 |
Bristol-Myers Squibb Company |
Fully human antibodies against human 4-1BB
|
|
AU2004287879C1
(en)
|
2003-11-04 |
2011-05-26 |
Novartis Vaccines And Diagnostics, Inc. |
Antagonist anti-CD40 monoclonal antibodies and methods for their use
|
|
US20070098718A1
(en)
|
2003-11-04 |
2007-05-03 |
Chiron |
Methods of therapy for b cell-related cancers
|
|
PL1682177T3
(pl)
|
2003-11-04 |
2011-03-31 |
Novartis Vaccines & Diagnostics Inc |
Zastosowanie antagonistycznych przeciwciał anty-CD40 do leczenia przewlekłej białaczki limfocytowej
|
|
US8277810B2
(en)
|
2003-11-04 |
2012-10-02 |
Novartis Vaccines & Diagnostics, Inc. |
Antagonist anti-CD40 antibodies
|
|
PT1684805E
(pt)
|
2003-11-04 |
2010-10-26 |
Novartis Vaccines & Diagnostic |
Utilização de anticorpos monoclonais antagonistas anti-cd40 para o tratamento do mieloma múltiplo
|
|
DK1680141T3
(da)
|
2003-11-04 |
2010-11-01 |
Novartis Vaccines & Diagnostic |
Fremgangsmåder til terapi til faste tumorer der udtrykker CD40-celleoverfladeantigenet
|
|
DE10352900A1
(de)
|
2003-11-11 |
2005-06-16 |
Tegenero Ag |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von B-CLL
|
|
US20050136055A1
(en)
|
2003-12-22 |
2005-06-23 |
Pfizer Inc |
CD40 antibody formulation and methods
|
|
EP1707627B1
(en)
|
2003-12-25 |
2012-11-14 |
Kyowa Hakko Kirin Co., Ltd. |
Antagonistic anti-CD40 antibody mutant
|
|
US20060099203A1
(en)
|
2004-11-05 |
2006-05-11 |
Pease Larry R |
B7-DC binding antibody
|
|
WO2006003179A2
(en)
|
2004-07-01 |
2006-01-12 |
Novo Nordisk A/S |
Antibodies binding to receptors kir2dl1, -2, 3 but not kir2ds4 and their therapeutic use
|
|
CA2601417C
(en)
|
2004-07-01 |
2018-10-30 |
Novo Nordisk A/S |
Human anti-kir antibodies
|
|
US20080057070A1
(en)
|
2004-11-04 |
2008-03-06 |
Chiron Corporation |
Antagonist Anti-Cd40 Monoclonal Antibodies and Methods for Their Use
|
|
DE102004063494A1
(de)
|
2004-12-23 |
2006-07-13 |
Tegenero Ag |
Antikörper
|
|
US20090196850A1
(en)
|
2005-01-06 |
2009-08-06 |
Novo Nordisk A/S |
Anti-Kir Combination Treatments and Methods
|
|
JP5295568B2
(ja)
|
2005-01-06 |
2013-09-18 |
ノヴォ ノルディスク アー／エス |
Ｋｉｒ結合剤およびその使用方法
|
|
PL1835937T3
(pl)
|
2005-01-06 |
2012-09-28 |
Novo Nordisk As |
Kompozycje i sposoby leczenia infekcji wirusowej
|
|
BRPI0607306A2
(pt)
|
2005-01-25 |
2009-08-25 |
Prolexys Pharmaceuticals Inc |
derivados de quinoxalina como agentes anti-tumor
|
|
US20070161644A1
(en)
|
2005-01-25 |
2007-07-12 |
Stockwell Brent R |
Erastin analogs and uses thereof
|
|
US8759490B2
(en)
|
2005-03-24 |
2014-06-24 |
Millennium Pharamaceuticals, Inc. |
Antibodies that bind OV064 and methods of use therefor
|
|
EP1868647A4
(en)
|
2005-03-24 |
2009-04-01 |
Millennium Pharm Inc |
OV064 BINDING ANTIBODIES AND METHOD FOR THEIR USE
|
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール，インク． |
Ｇｉｔｒ結合分子およびその使用
|
|
US20060240006A1
(en)
|
2005-04-20 |
2006-10-26 |
Chishih Chu |
Novel antibody structures derived from human germline sequences
|
|
MX2007013584A
(es)
|
2005-04-27 |
2008-04-22 |
Univ Indiana Res & Tech Corp |
Anticuerpos de isoforma de cspcna y sus usos.
|
|
EP3530736A3
(en)
|
2005-05-09 |
2019-11-06 |
ONO Pharmaceutical Co., Ltd. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
|
US7585960B2
(en)
|
2005-05-11 |
2009-09-08 |
Theramab Gmbh |
Nucleic acids encoding superagonistic anti-CD28 antibodies
|
|
AU2006247067B2
(en)
|
2005-05-18 |
2012-06-07 |
Novartis Ag |
Methods for diagnosis and treatment of proliferative disorders mediated by CD40 signaling
|
|
EP2312315A1
(en)
|
2005-05-18 |
2011-04-20 |
Novartis AG |
Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component
|
|
KR100694508B1
(ko)
|
2005-05-24 |
2007-03-13 |
울산대학교 산학협력단 |
Ｈｂｂｋ４항체를 포함하는 암 질환 치료용 약학조성물및 이를 이용한 암의 면역치료 방법
|
|
JP5027804B2
(ja)
|
2005-05-26 |
2012-09-19 |
シアトル ジェネティクス，インコーポレーテッド |
ヒト化抗ｃｄ４０抗体およびその使用方法
|
|
KR101704734B1
(ko)
|
2005-07-01 |
2017-02-09 |
이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
|
|
WO2007053661A2
(en)
|
2005-11-01 |
2007-05-10 |
Novartis Ag |
Uses of anti-cd40 antibodies
|
|
EP1945260B1
(en)
|
2005-11-01 |
2012-10-24 |
Novartis AG |
Uses of anti-cd40 antibodies
|
|
TWI461436B
(zh)
|
2005-11-25 |
2014-11-21 |
Kyowa Hakko Kirin Co Ltd |
人類ｃｄ１３４（ｏｘ４０）之人類單株抗體及其製造及使用方法
|
|
US8609816B2
(en)
|
2005-12-08 |
2013-12-17 |
Medarex, L.L.C. |
Human monoclonal antibodies to O8E
|
|
MX2008007140A
(es)
|
2005-12-09 |
2009-03-04 |
Seattle Genetics Inc |
Metodos para utilizar agentes de union a cd40.
|
|
US20090170834A1
(en)
|
2005-12-22 |
2009-07-02 |
Prolexys Pharmaceuticals, Inc. |
Fused Pyrimidones and Thiopyrimidones, and Uses Thereof
|
|
JP2009521484A
(ja)
|
2005-12-22 |
2009-06-04 |
プロレキシーズ ファーマシューティカルズ インコーポレイテッド |
３−アリール置換キナゾロンおよびその使用
|
|
US20110008368A1
(en)
|
2006-01-13 |
2011-01-13 |
Board Of Regents, The University Of Texas System |
Methods of modulating the ox40 receptor to treat cancer
|
|
SMP200800064B
(it)
|
2006-04-21 |
2009-11-06 |
Novartis Ag |
Composizioni farmaceutiche di anticorpi anti-cd40 antagonista
|
|
EP1854810A1
(en)
|
2006-05-09 |
2007-11-14 |
PanGenetics B.V. |
Deimmunized antagonistic anti-human CD40 monoclonal antibody from the ch5D12 antibody
|
|
WO2007149476A2
(en)
|
2006-06-19 |
2007-12-27 |
Trustees Of Columbia University In The City Of New York |
Assays for non-apoptotic cell death and uses thereof
|
|
KR100745488B1
(ko)
|
2006-07-04 |
2007-08-02 |
학교법인 울산공업학원 |
항-4-1ｂｂ 항체 및 화학 항암제를 포함하는 암 질환 예방및 치료용 약학 조성물
|
|
WO2008013987A2
(en)
|
2006-07-27 |
2008-01-31 |
Prolexys Pharmaceuticals, Inc. |
N-alkyl substituted piperazinylmethylquinazolinones and azepanylmethylquinazolinones
|
|
GB0620894D0
(en)
|
2006-10-20 |
2006-11-29 |
Univ Southampton |
Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
|
|
MX2009005189A
(es)
|
2006-11-15 |
2009-06-30 |
Medarex Inc |
Anticuerpos humanos monoclonales para btla y metodos de uso.
|
|
AU2008204433B2
(en)
|
2007-01-11 |
2014-03-13 |
Novo Nordisk A/S |
Anti-KIR antibodies, formulations, and uses thereof
|
|
CA2669412A1
(en)
|
2007-01-23 |
2008-07-31 |
Xencor, Inc. |
Optimized cd40 antibodies and methods of using the same
|
|
WO2008103470A2
(en)
|
2007-02-21 |
2008-08-28 |
Trustees Of Columbia University In The City Of New York |
Oncogenic-ras-signal dependent lethal compounds
|
|
EP2121008A4
(en)
|
2007-03-22 |
2010-03-31 |
Sloan Kettering Inst Cancer |
USE OF MONOCLONAL ANTIBODY 8H9
|
|
BRPI0811466A2
(pt)
|
2007-05-07 |
2014-10-14 |
Medimmune Llc |
Anticorpo anti-icos isolado, ácido nucleico, vetor, célula isolada, métodos para produzir um anticorpo, para tratar uma doença ou distúrbio, para tratar ou prevenir a rejeição em um paciente de transplante humano, para tratar uma malignidade de célula t em um ser humano, para esgotar células t que expressam icos em um paciente humano, para romper a arquitetura do centro germinal em um órgão linfóide secundário de um primata, para esgotar células b centrais germinais de órgão linfóide secundário de um primata, e para esgotar células b comutadas em classes circulantes em um primata, e, composição farmacêutica.
|
|
KR101486026B1
(ko)
|
2007-05-10 |
2015-01-22 |
도그우드 파마슈티컬스, 아이엔씨. |
플루오렌, 안트라센, 잔텐, 디벤조수베론 및 아크리딘의 유도체 및 이의 용도
|
|
KR20080107050A
(ko)
|
2007-06-05 |
2008-12-10 |
울산대학교 산학협력단 |
항-ｃｄ１３７ 단일클론 항체를 포함하는 만성이식편대숙주 질환의 예방 또는 치료용 약학적 조성물
|
|
PT2170959E
(pt)
|
2007-06-18 |
2014-01-07 |
Merck Sharp & Dohme |
Anticorpos para o receptor humano de morte programada pd-1
|
|
WO2009002553A1
(en)
*
|
2007-06-25 |
2008-12-31 |
Prolexys Pharmaceuticals, Inc. |
Methods of treating multiple myeloma and resistant cancers
|
|
US20090028857A1
(en)
|
2007-07-23 |
2009-01-29 |
Cell Genesys, Inc. |
Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
|
|
RU2491095C2
(ru)
|
2007-11-09 |
2013-08-27 |
Новартис Аг |
Применения анти-cd40-антител
|
|
AR069747A1
(es)
|
2007-11-30 |
2010-02-17 |
Medarex Inc |
Conjugado anticuerpo monoclonal anti-b7h4- farmaco y metodos de utilizacion
|
|
EP2229186A2
(en)
|
2007-12-04 |
2010-09-22 |
Alnylam Pharmaceuticals Inc. |
Carbohydrate conjugates as delivery agents for oligonucleotides
|
|
AU2009206506B2
(en)
|
2008-01-23 |
2013-01-10 |
Xencor, Inc. |
Optimized CD40 antibodies and methods of using the same
|
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
|
US20110229460A1
(en)
|
2008-05-01 |
2011-09-22 |
Gtc Biotherapeutics, Inc. |
anti-cd137 antibody as an agent in the treatment of inflammatory conditions
|
|
CA2729567C
(en)
|
2008-06-30 |
2018-04-24 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-cd27 antibody
|
|
WO2010009346A2
(en)
|
2008-07-16 |
2010-01-21 |
Baylor Research Institute |
Hiv vaccine based on targeting maximized gag and nef to dendritic cells
|
|
MX2011000501A
(es)
|
2008-07-18 |
2011-05-23 |
Squibb Bristol Myers Co |
Composiciones monovalentes para union a cd28 y metodos de uso.
|
|
AR073459A1
(es)
|
2008-07-18 |
2010-11-10 |
Domantis Ltd |
Composiciones de dominios variables de anticuerpos monovalentes para la union de cd28 y metodos de uso
|
|
US20110097339A1
(en)
|
2008-07-18 |
2011-04-28 |
Domantis Limited |
Compositions monovalent for CD28 binding and methods of use
|
|
AU2009290543B2
(en)
|
2008-09-12 |
2015-09-03 |
Oxford University Innovation Limited |
PD-1 specific antibodies and uses thereof
|
|
AU2009290544B2
(en)
|
2008-09-12 |
2015-07-16 |
Oxford University Innovation Limited |
PD-1 specific antibodies and uses thereof
|
|
WO2010036959A2
(en)
|
2008-09-26 |
2010-04-01 |
Dana-Farber Cancer Institute |
Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor
|
|
WO2010042433A1
(en)
|
2008-10-06 |
2010-04-15 |
Bristol-Myers Squibb Company |
Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases
|
|
US8709411B2
(en)
|
2008-12-05 |
2014-04-29 |
Novo Nordisk A/S |
Combination therapy to enhance NK cell mediated cytotoxicity
|
|
MX356367B
(es)
|
2008-12-09 |
2018-05-25 |
Genentech Inc |
Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
|
|
WO2010082912A1
(en)
|
2009-01-15 |
2010-07-22 |
Avalon Pharmaceuticals |
Derivatives of multi-ring aromatic compounds and uses as anti-tumor agents
|
|
AU2010216152B2
(en)
|
2009-02-17 |
2015-05-14 |
Ucb Biopharma Sprl |
Antibody molecules having specificity for human OX40
|
|
GB0903325D0
(en)
|
2009-02-26 |
2009-04-08 |
Univ Aberdeen |
Antibody molecules
|
|
CN108373509A
(zh)
|
2009-03-10 |
2018-08-07 |
贝勒研究院 |
靶向抗原呈递细胞的抗病毒疫苗
|
|
BRPI1009455A2
(pt)
|
2009-03-10 |
2016-03-01 |
Baylor Res Inst |
anticorpos anti-c40 e usos dos mesmos
|
|
US8647623B2
(en)
|
2009-04-10 |
2014-02-11 |
Kyowa Hakko Kirin Co., Ltd |
Method for treatment of blood tumor using anti-TIM-3 antibody
|
|
JP5694921B2
(ja)
|
2009-04-20 |
2015-04-01 |
協和発酵キリン株式会社 |
アミノ酸変異が導入されたＩｇＧ２を有する抗体
|
|
WO2010132389A2
(en)
|
2009-05-14 |
2010-11-18 |
University Of Maryland, Baltimore |
Methods for treating cancers and diseases associated with 4-1bb (cd137) expression
|
|
CA2769473A1
(en)
|
2009-07-31 |
2011-02-03 |
N.V. Organon |
Fully human antibodies to btla
|
|
IN2015DN02826A
(enExample)
|
2009-09-03 |
2015-09-11 |
Merck Sharp & Dohme |
|
|
WO2011031063A2
(ko)
|
2009-09-09 |
2011-03-17 |
울산대학교 산학협력단 |
항 4-1bb 항체를 포함하는 대사성 질환의 예방 또는 치료용 조성물
|
|
EP3279215B1
(en)
|
2009-11-24 |
2020-02-12 |
MedImmune Limited |
Targeted binding agents against b7-h1
|
|
JP5950824B2
(ja)
|
2009-12-07 |
2016-07-13 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
抗腫瘍抗体療法を増強するための方法
|
|
AU2010339359A1
(en)
|
2009-12-29 |
2012-07-26 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-CD27 antibody
|
|
KR20110085038A
(ko)
|
2010-01-19 |
2011-07-27 |
울산대학교 산학협력단 |
항 ｃｄ137-항체 및 독소 결합물을 이용한 ｃｄ137 양성세포의 제거방법
|
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
|
US8785604B2
(en)
|
2010-02-18 |
2014-07-22 |
Effimune |
Anti-CD28 humanized antibodies
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
DK2542256T3
(da)
|
2010-03-04 |
2019-08-26 |
Macrogenics Inc |
Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
|
|
EP2796467B1
(en)
|
2010-03-31 |
2018-03-28 |
Boehringer Ingelheim International GmbH |
Anti-CD40 antibodies
|
|
EP2560994B1
(en)
|
2010-04-08 |
2016-10-12 |
JN Biosciences LLC |
Antibodies to cd122
|
|
US20120213771A1
(en)
|
2010-04-13 |
2012-08-23 |
Celldex Therapeutics Inc. |
Antibodies that bind human cd27 and uses thereof
|
|
JP6002659B2
(ja)
|
2010-04-13 |
2016-10-05 |
セルデックス・セラピューティクス・インコーポレイテッド |
ヒトｃｄ２７に結合する抗体およびその使用
|
|
CN103079644B
(zh)
|
2010-06-11 |
2017-02-15 |
协和发酵麒麟株式会社 |
抗tim‑3抗体
|
|
CA2804550C
(en)
|
2010-07-09 |
2021-01-05 |
Bionovion Holding B.V. |
Agonistic antibody to cd27
|
|
LT2609118T
(lt)
|
2010-08-23 |
2017-04-25 |
Board Of Regents, The University Of Texas System |
Anti-ox40 antikūnai ir jų panaudojimo būdai
|
|
NZ729044A
(en)
|
2010-09-09 |
2020-07-31 |
Pfizer |
4-1bb binding molecules
|
|
US9290760B2
(en)
|
2010-09-15 |
2016-03-22 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
|
AR083847A1
(es)
|
2010-11-15 |
2013-03-27 |
Novartis Ag |
Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
|
|
CA2818684C
(en)
|
2010-11-22 |
2023-02-21 |
Innate Pharma Sa |
Nk cell modulating treatments and methods for treatment of hematological malignancies
|
|
WO2012075111A1
(en)
|
2010-11-30 |
2012-06-07 |
Novartis Ag |
Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
|
|
WO2012087928A2
(en)
|
2010-12-20 |
2012-06-28 |
The Rockefeller University |
Modulating agonistic tnfr antibodies
|
|
US9956236B2
(en)
|
2011-02-07 |
2018-05-01 |
Cornell University |
Methods for increasing immune responses using agents that directly bind to and activate IRE-1
|
|
ES2734076T3
(es)
|
2011-02-17 |
2019-12-04 |
Kyowa Hakko Kirin Co Ltd |
Preparación farmacéutica de anticuerpo anti-CD40 muy concentrada
|
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
HUE065915T2
(hu)
|
2011-03-11 |
2024-06-28 |
Beth Israel Deaconess Medical Ct Inc |
Anti-CD40 antitestek és alkalmazásaik
|
|
KR102023661B1
(ko)
|
2011-03-31 |
2019-09-23 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
Icos에 대한 항체 및 이의 용도
|
|
US20140178368A1
(en)
|
2011-04-19 |
2014-06-26 |
Leslie Lynne SHARP |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
CA2833636A1
(en)
|
2011-04-20 |
2012-10-26 |
Amplimmune, Inc. |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
NO2699601T3
(enExample)
|
2011-04-21 |
2018-06-16 |
|
|
|
EP2703486B1
(en)
|
2011-04-25 |
2018-03-07 |
Daiichi Sankyo Company, Limited |
Anti-b7-h3 antibody
|
|
KR102037432B1
(ko)
|
2011-04-29 |
2019-11-27 |
아펙시젠, 인코포레이티드 |
항-cd40 항체 및 사용 방법
|
|
US9067997B2
(en)
|
2011-05-25 |
2015-06-30 |
Innate Pharma Sa |
Anti-KIR antibodies for the treatment of inflammatory and autoimmune disorders
|
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
|
KR102119840B1
(ko)
|
2011-07-11 |
2020-06-09 |
아이크노스 사이언스 에스. 아. |
Ox40에 결합하는 항체 및 이들의 용도
|
|
US9676854B2
(en)
|
2011-08-15 |
2017-06-13 |
Medimmune, Llc |
Anti-B7-H4 antibodies and their uses
|
|
JP6038920B2
(ja)
|
2011-08-23 |
2016-12-07 |
ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム |
抗ｏｘ４０抗体およびそれを使用する方法
|
|
GB201115280D0
(en)
|
2011-09-05 |
2011-10-19 |
Alligator Bioscience Ab |
Antibodies, uses and methods
|
|
US20130108641A1
(en)
|
2011-09-14 |
2013-05-02 |
Sanofi |
Anti-gitr antibodies
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
US9422351B2
(en)
|
2011-11-03 |
2016-08-23 |
The Trustees Of The University Of Pennsylvania |
Isolated B7-H4 specific compositions and methods of use thereof
|
|
UA112203C2
(uk)
|
2011-11-11 |
2016-08-10 |
Юсб Фарма С.А. |
Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини
|
|
JO3787B1
(ar)
|
2012-03-15 |
2021-01-31 |
Janssen Biotech Inc |
أجسام مضادة بشرية ضد cd27 و طرق و استخداماتها
|
|
US9580398B2
(en)
|
2012-04-02 |
2017-02-28 |
The Trustees Of Columbia University In The City Of New York |
Compounds, compositions, and methods for modulating ferroptosis and treating excitotoxic disorders
|
|
US20140004131A1
(en)
|
2012-05-04 |
2014-01-02 |
Novartis Ag |
Antibody formulation
|
|
US9175082B2
(en)
|
2012-05-31 |
2015-11-03 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
|
KR101566539B1
(ko)
|
2012-06-08 |
2015-11-05 |
국립암센터 |
신규한 Ｔｈ2 세포 전환용 에피토프 및 이의 용도
|
|
US9695133B2
(en)
|
2012-07-13 |
2017-07-04 |
The Trustees Of Columbia University In The City Of New York |
Quinazolinone-based oncogenic-RAS-selective lethal compounds and their use
|
|
US9268936B2
(en)
|
2012-07-27 |
2016-02-23 |
Mandiant, Llc |
Physical memory forensics system and method
|
|
CN111499755A
(zh)
|
2012-08-03 |
2020-08-07 |
丹娜法伯癌症研究院 |
抗-pd-l1和pd-l2双结合抗体单一试剂及其使用方法
|
|
EP2890720B1
(en)
|
2012-08-30 |
2019-07-17 |
The General Hospital Corporation |
Compositions and methods for treating cancer
|
|
ES2684552T3
(es)
|
2012-09-03 |
2018-10-03 |
Inserm - Institut National De La Santé Et De La Recherche Médicale |
Anticuerpos dirigidos contra ICOS para tratar la enfermedad de injerto contra hospedador
|
|
BR112015007184A2
(pt)
|
2012-10-02 |
2017-08-08 |
Bristol Myers Squibb Co |
combinação de anticorpos anti-kir e anticorpos anti-pd-1 para tratar câncer
|
|
US10195288B2
(en)
|
2012-10-11 |
2019-02-05 |
Daiichi Sankyo Company, Limited |
Antibody-drug conjugate
|
|
EP2910573B1
(en)
|
2012-10-19 |
2020-02-19 |
Daiichi Sankyo Company, Limited |
Antibody-drug conjugate produced by binding through linker having hydrophilic structure
|
|
EP2912063A1
(en)
|
2012-10-23 |
2015-09-02 |
Bristol-Myers Squibb Company |
Combination of anti-kir and anti-ctla-4 antibodies to treat cancer
|
|
JPWO2014065402A1
(ja)
|
2012-10-26 |
2016-09-08 |
株式会社ペルセウスプロテオミクス |
抗ヒトｃｄ４０モノクローナル抗体及びその利用
|
|
JP2016011258A
(ja)
|
2012-10-26 |
2016-01-21 |
株式会社ペルセウスプロテオミクス |
抗ヒトｃｄ４０モノクローナル抗体及びその利用
|
|
CA2888763A1
(en)
|
2012-10-30 |
2014-05-08 |
Apexigen, Inc. |
Anti-cd40 antibodies and methods of use
|
|
AU2013361275B2
(en)
|
2012-12-19 |
2016-11-24 |
Amplimmune, Inc. |
Anti-human B7-H4 antibodies and their uses
|
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
|
EP2960623A4
(en)
|
2013-02-20 |
2017-02-15 |
Nec Corporation |
Spatial stabilization device, spatial stabilization method, and storage medium for spatial stabilization program
|
|
MX2015010777A
(es)
|
2013-03-14 |
2016-04-25 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-b7-h4.
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
US20140322236A1
(en)
|
2013-03-15 |
2014-10-30 |
Sdix, Llc |
Anti-human adora2a antibodies
|
|
WO2014140374A2
(en)
|
2013-03-15 |
2014-09-18 |
Novo Nordisk A/S |
Monovalent cd27 antibodies
|
|
RS57840B1
(sr)
|
2013-03-18 |
2018-12-31 |
Biocerox Prod Bv |
Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebe
|
|
WO2014165422A1
(en)
|
2013-04-02 |
2014-10-09 |
Merck Sharp & Dohme Corp. |
Immunohistochemical assay for detecting expression of programmed death ligand 1 (pd-l1) in tumor tissue
|
|
AU2014268298B2
(en)
|
2013-05-24 |
2019-01-17 |
Medlmmune, Llc |
Anti-B7-H5 antibodies and their uses
|
|
CA3175360C
(en)
|
2013-05-31 |
2024-05-28 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
|
EP3003390B1
(en)
|
2013-06-06 |
2021-07-07 |
Pierre Fabre Médicament |
Anti-c10orf54 antibodies and uses thereof
|
|
GB201311487D0
(en)
|
2013-06-27 |
2013-08-14 |
Alligator Bioscience Ab |
Bispecific molecules
|
|
CN105682683A
(zh)
|
2013-08-02 |
2016-06-15 |
阿杜罗生物科技控股有限公司 |
结合cd27激动剂以及免疫检查点抑制以用于免疫刺激
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
US10077305B2
(en)
|
2013-09-10 |
2018-09-18 |
Medimmune Limited |
Antibodies against PD-1 and uses thereof
|
|
WO2015051149A1
(en)
|
2013-10-04 |
2015-04-09 |
The Trustees Of Columbia University In The City Of New York |
Sorafenib analogs and uses thereof
|
|
EP3066128B1
(en)
|
2013-11-06 |
2018-10-31 |
Bristol-Myers Squibb Company |
Combination of anti-kir and anti-cs1 antibodies to treat multiple myeloma
|
|
EP3076962A4
(en)
|
2013-12-02 |
2017-10-18 |
The Trustees of Columbia University in the City of New York |
Modulating ferroptosis and treating excitotoxic disorders
|
|
GB201322583D0
(en)
|
2013-12-19 |
2014-02-05 |
Alligator Bioscience Ab |
Antibodies
|
|
CN105611944A
(zh)
|
2013-12-20 |
2016-05-25 |
豪夫迈·罗氏有限公司 |
抗ang2抗体和cd40激动剂的组合疗法
|
|
EP3094332B1
(en)
|
2014-01-15 |
2018-09-12 |
The Trustees of Columbia University in the City of New York |
Carbonyl erastin analogs and their use
|
|
US10899840B2
(en)
|
2014-02-04 |
2021-01-26 |
Pfizer Inc. |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
|
WO2015134988A1
(en)
|
2014-03-07 |
2015-09-11 |
Bristol-Myers Squibb Company |
Method of using antibody polypeptides that antagonize cd40 to treat ibd
|
|
WO2015179236A1
(en)
|
2014-05-21 |
2015-11-26 |
Pfizer Inc. |
Combination of an anti-ccr4 antibody and a 4-1bb agonist for treating cancer
|
|
LT3148579T
(lt)
|
2014-05-28 |
2021-05-25 |
Agenus Inc. |
Anti-gitr antikūnai ir jų panaudojimo būdai
|
|
EP3149040A1
(en)
|
2014-05-29 |
2017-04-05 |
Spring Bioscience Corporation |
Anti-b7-h3 antibodies and diagnostic uses thereof
|
|
EP3148981A4
(en)
|
2014-05-30 |
2017-11-08 |
The Trustees of Columbia University in the City of New York |
Multivalent ras binding compounds
|
|
PL3151921T3
(pl)
|
2014-06-06 |
2020-02-28 |
Bristol-Myers Squibb Company |
Przeciwciała przeciwko receptorowi indukowanego glukokortykoidami czynnika martwicy nowotworu (gitr) i ich zastosowania
|
|
WO2015188047A1
(en)
|
2014-06-06 |
2015-12-10 |
University Of Maryland, Baltimore |
ANTI-CD-137 MONOCLONAL ANTIBODIES WITH DISTINCT FcγR BINDING ABILITIES FOR TREATMENT OF CANCER OR AUTOIMMUNITY
|
|
WO2015198147A1
(en)
|
2014-06-23 |
2015-12-30 |
Theramab Llc |
Compositions and methods for safe and effective immunotherapy
|
|
WO2016005421A1
(en)
|
2014-07-09 |
2016-01-14 |
Novo Nordisk A/S |
Motorized drug delivery device
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
EP3180087B1
(en)
|
2014-08-12 |
2019-03-13 |
Alligator Bioscience AB |
Combination therapies with anti cd40 antibodies
|
|
EP3626740A1
(en)
|
2014-08-14 |
2020-03-25 |
F. Hoffmann-La Roche AG |
Combination therapy of antibodies activating human cd40 and antibodies against human pd-l1
|
|
US20170233485A1
(en)
|
2014-08-18 |
2017-08-17 |
Biogen Ma Inc. |
Anti-cd40 antibodies and uses thereof
|
|
EP3183269A2
(en)
|
2014-08-22 |
2017-06-28 |
Bristol-Myers Squibb Company |
Treatment of cancer using a combination of an anti-pd-1 antibody and an anti-cd137 antibody
|
|
KR102485788B1
(ko)
|
2014-08-27 |
2023-01-09 |
메모리얼 슬로안 케터링 캔서 센터 |
항체, 조성물 및 용도
|
|
ES2774380T3
(es)
|
2014-08-29 |
2020-07-20 |
Hoffmann La Roche |
Politerapia de inmunocitocinas de variante de IL-2 dirigida a tumor y anticuerpos frente a PD-L1 humano
|
|
TW201625689A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
抗－ｂ７－ｈ４抗體及免疫結合物
|
|
RU2017115315A
(ru)
|
2014-10-03 |
2018-11-08 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Антитела к рецептору глюкокортикоид-индуцированного фактора некроза опухоли (gitr) и способы их применения
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
GB201419094D0
(en)
|
2014-10-27 |
2014-12-10 |
Agency Science Tech & Res |
Anti-TIM-3-antibodies
|
|
AU2015340056A1
(en)
|
2014-10-27 |
2017-05-25 |
Agency For Science, Technology And Research |
Anti-TIM-3 antibodies
|
|
US11639384B2
(en)
|
2014-10-28 |
2023-05-02 |
University Children's Hospital Tübingen |
Treatment of pediatric BCP-ALL patients with an anti-KIR antibody
|
|
BR112017008959A2
(pt)
|
2014-10-29 |
2018-01-16 |
Seattle Genetics, Inc. |
método para tratamento de uma doença.
|
|
US10626176B2
(en)
|
2014-10-31 |
2020-04-21 |
Jounce Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind B7-H4
|
|
MY193661A
(en)
|
2014-11-06 |
2022-10-24 |
Hoffmann La Roche |
Anti-tim3 antibodies and methods of use
|
|
KR102693806B1
(ko)
|
2014-12-11 |
2024-08-09 |
피에르 파브르 메디카먼트 |
항-c10orf54 항체들 및 그들의 용도들
|
|
US9963509B2
(en)
|
2014-12-23 |
2018-05-08 |
Full Spectrum Genetics, Inc. |
Anti-B7H3 binding compounds and uses thereof
|
|
US20160200815A1
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
|
WO2017058716A1
(en)
|
2015-09-28 |
2017-04-06 |
Vivace Therapeutics, Inc. |
Tricyclic compounds
|
|
US20190008961A1
(en)
|
2016-01-07 |
2019-01-10 |
The Broad Institute, Inc. |
Compounds and methods for increasing tumor infiltration by immune cells
|
|
WO2018118711A1
(en)
|
2016-12-19 |
2018-06-28 |
The Trustees Of Columbia University In The City Of New York |
Small molecule ferroptosis inducers
|
|
CN108409737B
(zh)
|
2017-02-10 |
2020-07-03 |
华东理工大学 |
4-甲氧基苯基取代四氢-β-咔啉哌嗪二酮类衍生物及其应用
|
|
WO2018218087A1
(en)
|
2017-05-24 |
2018-11-29 |
K-Gen, Inc. |
Methods of cancer treatment
|
|
US12213977B2
(en)
*
|
2017-06-28 |
2025-02-04 |
The Regents Of The University Of California |
Methods and compositions for treating melanoma
|
|
US20200397817A1
(en)
*
|
2017-11-30 |
2020-12-24 |
SHIEH, Darbin |
Method for predicting and modulating susceptibility of cancer cell to programmed cell death
|
|
WO2019113004A1
(en)
*
|
2017-12-04 |
2019-06-13 |
Memorial Sloan Kettering Cancer Center |
Methods of cancer treatment via regulated ferroptosis
|
|
US11098040B2
(en)
|
2018-02-28 |
2021-08-24 |
Ferro Therapeutics, Inc. |
Compounds and methods of use
|
|
US11040964B2
(en)
|
2019-02-27 |
2021-06-22 |
Ferro Therapeutics, Inc. |
Compounds and methods of use
|