JP2023508142A5 - - Google Patents
Info
- Publication number
- JP2023508142A5 JP2023508142A5 JP2022538727A JP2022538727A JP2023508142A5 JP 2023508142 A5 JP2023508142 A5 JP 2023508142A5 JP 2022538727 A JP2022538727 A JP 2022538727A JP 2022538727 A JP2022538727 A JP 2022538727A JP 2023508142 A5 JP2023508142 A5 JP 2023508142A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- acrylic acid
- oxadiazole
- phenyl
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025077120A JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19219531 | 2019-12-23 | ||
| EP19219531.1 | 2019-12-23 | ||
| EP20162545.6 | 2020-03-11 | ||
| EP20162545 | 2020-03-11 | ||
| EP20189623 | 2020-08-05 | ||
| EP20189623.0 | 2020-08-05 | ||
| EP20205768.3 | 2020-11-04 | ||
| EP20205768 | 2020-11-04 | ||
| PCT/GB2020/053357 WO2021130492A1 (en) | 2019-12-23 | 2020-12-23 | Carboxy derivatives with antiinflammatory properties |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077120A Division JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023508142A JP2023508142A (ja) | 2023-03-01 |
| JP2023508142A5 true JP2023508142A5 (enExample) | 2023-12-22 |
| JP7679384B2 JP7679384B2 (ja) | 2025-05-19 |
Family
ID=74104118
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022538727A Active JP7679384B2 (ja) | 2019-12-23 | 2020-12-23 | 抗炎症特性を有するカルボン酸誘導体 |
| JP2025077120A Pending JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077120A Pending JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US12617762B2 (enExample) |
| EP (2) | EP4081511B3 (enExample) |
| JP (2) | JP7679384B2 (enExample) |
| KR (1) | KR20220119425A (enExample) |
| CN (1) | CN115066418B (enExample) |
| AU (1) | AU2020412853A1 (enExample) |
| BR (1) | BR112022011933A2 (enExample) |
| CA (2) | CA3161424C (enExample) |
| CL (1) | CL2022001722A1 (enExample) |
| CO (1) | CO2022008652A2 (enExample) |
| CR (1) | CR20220300A (enExample) |
| DK (1) | DK4081511T6 (enExample) |
| EC (1) | ECSP22049370A (enExample) |
| ES (1) | ES2987014T7 (enExample) |
| FI (1) | FI4081511T6 (enExample) |
| HR (1) | HRP20241378T4 (enExample) |
| HU (1) | HUE068571T2 (enExample) |
| IL (1) | IL293982B2 (enExample) |
| JO (1) | JOP20220162A1 (enExample) |
| LT (1) | LT4081511T (enExample) |
| MA (1) | MA58170B1 (enExample) |
| MD (1) | MD4081511T2 (enExample) |
| MX (1) | MX2022007846A (enExample) |
| PE (1) | PE20221584A1 (enExample) |
| PH (1) | PH12022551546A1 (enExample) |
| PL (1) | PL4081511T6 (enExample) |
| RS (1) | RS66019B1 (enExample) |
| SI (1) | SI4081511T2 (enExample) |
| TW (1) | TWI891696B (enExample) |
| WO (1) | WO2021130492A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL287444B2 (en) | 2019-04-30 | 2024-09-01 | Sitryx Therapeutics Ltd | Itaconic acid derivatives and uses thereof in treating an inflammatory disease or a disease associated with an undesirable immune response |
| JP7137696B2 (ja) | 2019-05-14 | 2022-09-14 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を予防するための方法および組成物 |
| KR20230092863A (ko) | 2020-06-11 | 2023-06-26 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
| EP4192821A1 (en) | 2020-08-05 | 2023-06-14 | Sitryx Therapeutics Limited | Alpha,beta unsaturated methacrylic esters with anti-inflammatory properties |
| US12678419B2 (en) | 2020-10-27 | 2026-07-14 | Sitryx Therapeutics Limited | Compounds |
| WO2022229617A1 (en) * | 2021-04-26 | 2022-11-03 | Sitryx Therapeutics Limited | 2-methylene-4-oxo-butanoic acid drivatives for the treatment of inflammation |
| MX2023013851A (es) | 2021-05-24 | 2023-12-08 | Provention Bio Inc | Metodos para el tratamiento de diabetes tipo 1. |
| WO2022269251A1 (en) * | 2021-06-22 | 2022-12-29 | Sitryx Therapeutics Limited | Acrylamide derivatives useful as anti-inflammatory agents |
| CN113499453B (zh) * | 2021-07-20 | 2022-10-21 | 徐州医科大学 | 自噬抑制及抗炎联合温合光热诊疗剂及其制备方法与应用 |
| WO2023017269A1 (en) | 2021-08-11 | 2023-02-16 | Sitryx Therapeutics Limited | Derivatives of itaconic acid and their use as anti-inflammatory agents |
| WO2023247958A1 (en) | 2022-06-22 | 2023-12-28 | Sitryx Therapeutics Limited | Oxadiazole derivatives, preparation process thereof and their use in treating inflammatory diseases |
| WO2024089421A1 (en) | 2022-10-25 | 2024-05-02 | Sitryx Therapeutics Limited | Tetrazole derivatives |
| AU2023392783A1 (en) * | 2022-12-15 | 2025-06-19 | Sitryx Therapeutics Limited | Substituted pyridines for use in treating or preventing inflammatory diseases or diseases associated with an undesirable immune response |
| KR102864655B1 (ko) * | 2023-01-19 | 2025-09-29 | 대한민국 | 뎅기바이러스 감염에 의한 질환의 예방 또는 치료용 약학적 조성물 |
| CN115819186B (zh) * | 2023-02-14 | 2023-05-16 | 广东银珠医药科技有限公司 | 一种3,5-二氯苯甲醇的新型制备方法 |
| CN117205194A (zh) * | 2023-05-10 | 2023-12-12 | 苏州大学 | 衣康酸或其衍生物在制备预防或治疗急性移植物抗宿主病药物中的应用 |
| CN116725998A (zh) * | 2023-07-20 | 2023-09-12 | 中国科学技术大学 | 特立氟胺在抑制nlrp3炎症小体活化中的应用 |
| CN118812769B (zh) * | 2024-07-02 | 2025-09-26 | 南京工业大学 | 一种衣康酰肼诱导的Janus结构聚合物表皮贴片电极及其制备方法 |
| CN119792264B (zh) * | 2025-03-14 | 2025-06-10 | 华中科技大学同济医学院附属同济医院 | 丁酰肼在制备预防或治疗copd的药物中的应用 |
| CN120585811B (zh) * | 2025-08-07 | 2026-01-06 | 华南理工大学 | 4-辛基衣康酸在制备改善肺动脉高压的药物中的应用 |
| CN121668151A (zh) * | 2026-02-11 | 2026-03-17 | 武汉大学人民医院（湖北省人民医院） | 衣康酸类化合物在制备治疗视网膜动脉阻塞药物中的用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1963672A1 (de) | 1969-12-19 | 1971-06-24 | Hoechst Ag | Dithiophosphorsaeureester,ihre Herstellung und Anwendung als Schaedlingsbekaempfungsmittel |
| DE2047465A1 (de) | 1970-09-26 | 1972-03-30 | Farbwerke Hoechst AG, vorm Meister Lucius & Bruning, 6000 Frankfurt | Neue Oxdiazole und Verfahren zu lh rer Herstellung |
| NL7413713A (nl) | 1973-11-02 | 1975-05-07 | Ciba Geigy | Werkwijze voor het bereiden van nieuwe esters. |
| DE2805756A1 (de) | 1978-02-10 | 1979-08-16 | Bayer Ag | N-azolylalkyl-aniline sowie verfahren zu ihrer herstellung |
| JPS6212776A (ja) | 1985-07-10 | 1987-01-21 | Taiho Yakuhin Kogyo Kk | ロ−ダニン誘導体 |
| EP0521622B1 (en) | 1991-07-03 | 1997-08-13 | PHARMACIA & UPJOHN COMPANY | Pyrazolopyrimidine and pyrimidinyl bisphosphonic esters as anti-inflammatories |
| EP0724573A1 (en) * | 1993-10-20 | 1996-08-07 | PHARMACIA & UPJOHN COMPANY | Pyrimidinones as antiarthritic and anti-inflammatories |
| US6566384B1 (en) | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| KR100538968B1 (ko) | 1997-02-18 | 2006-07-11 | 후지 샤신 필름 가부시기가이샤 | 포지티브감광성조성물 |
| US5965718A (en) | 1997-10-24 | 1999-10-12 | The Scripps Research Institute | Analogs of sarcodictyin and eleutherobin |
| JP2001354625A (ja) | 2000-04-12 | 2001-12-25 | Dainippon Ink & Chem Inc | 新規なイタコン酸エステル及びその製造方法 |
| JP4102014B2 (ja) | 2000-10-03 | 2008-06-18 | 富士フイルム株式会社 | 感光性平版印刷版 |
| JP2004315791A (ja) | 2003-03-28 | 2004-11-11 | Tokyo Ohka Kogyo Co Ltd | ジカルボン酸モノエステル化合物およびその製造方法ならびに重合体 |
| TW201206429A (en) | 2010-07-08 | 2012-02-16 | Merck Serono Sa | Substituted oxadiazole derivatives |
| US8637536B2 (en) * | 2010-12-06 | 2014-01-28 | Glaxo Group Limited | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2 |
| MX386935B (es) | 2013-03-14 | 2025-03-04 | Alkermes Pharma Ireland Ltd | Profármacos de fumaratos y su uso en el tratamiento de diferentes enfermedades. |
| WO2014152263A1 (en) | 2013-03-15 | 2014-09-25 | Karyopharm Therapeutics Inc. | Exo olefin-containing nuclear transport modulators and uses thereof |
| AU2014290368B2 (en) * | 2013-07-18 | 2019-07-11 | Baylor College Of Medicine | Methods and compositions for treatment of muscle wasting, muscle weakness, and/or cachexia |
| CN103923105B (zh) * | 2014-04-17 | 2016-08-24 | 北京大学 | 2-中氮茚甲酰胺类化合物及其制备和用途 |
| EP3416634A4 (en) | 2016-02-15 | 2019-10-09 | Artyomov, Maxim | IMMUNOMODULATORY AGENTS AND METHOD FOR USE THEREOF |
| US20200375929A1 (en) | 2017-08-14 | 2020-12-03 | Washington University | Methods and compositions for the treatment of diseases associated with cancer, inflammation, or immune response |
| WO2019066827A1 (en) | 2017-09-27 | 2019-04-04 | Intel Corporation | CHARACTERISTICS AND APPROACHES TO GRID ASSISTANCE FOR ELECTRON BEAM DIRECT WRITE LITHOGRAPHY (EBDW) |
| EP3813815B1 (en) | 2018-06-29 | 2026-01-28 | Ergon Pharmaceuticals, LLC | Compositions and methods of using itaconic acid derivatives |
| IL287444B2 (en) | 2019-04-30 | 2024-09-01 | Sitryx Therapeutics Ltd | Itaconic acid derivatives and uses thereof in treating an inflammatory disease or a disease associated with an undesirable immune response |
| US20200377510A1 (en) * | 2019-05-30 | 2020-12-03 | Auransa Inc. | Derivatives of piperlongumine and uses thereof |
| CN110731955B (zh) | 2019-10-28 | 2023-05-02 | 中山大学 | 衣康酸二甲酯在预防和治疗溃疡性结肠炎及其癌变中的应用 |
| EP4192821A1 (en) | 2020-08-05 | 2023-06-14 | Sitryx Therapeutics Limited | Alpha,beta unsaturated methacrylic esters with anti-inflammatory properties |
| EP4200275A2 (en) | 2020-08-21 | 2023-06-28 | Sitryx Therapeutics Limited | Fumarate derivatives and their medical use |
| US12678419B2 (en) | 2020-10-27 | 2026-07-14 | Sitryx Therapeutics Limited | Compounds |
| EP4237408A1 (en) | 2020-10-29 | 2023-09-06 | Sitryx Therapeutics Limited | Itaconic acid derivatives |
| EP4237404A1 (en) | 2020-10-29 | 2023-09-06 | Sitryx Therapeutics Limited | Novel compounds |
-
2020
- 2020-12-23 FI FIEP20830293.5T patent/FI4081511T6/fi active
- 2020-12-23 HR HRP20241378TT patent/HRP20241378T4/hr unknown
- 2020-12-23 BR BR112022011933A patent/BR112022011933A2/pt unknown
- 2020-12-23 MA MA58170A patent/MA58170B1/fr unknown
- 2020-12-23 CR CR20220300A patent/CR20220300A/es unknown
- 2020-12-23 EP EP20830293.5A patent/EP4081511B3/en active Active
- 2020-12-23 IL IL293982A patent/IL293982B2/en unknown
- 2020-12-23 MD MDE20221214T patent/MD4081511T2/ro unknown
- 2020-12-23 JP JP2022538727A patent/JP7679384B2/ja active Active
- 2020-12-23 ES ES20830293T patent/ES2987014T7/es active Active
- 2020-12-23 CA CA3161424A patent/CA3161424C/en active Active
- 2020-12-23 WO PCT/GB2020/053357 patent/WO2021130492A1/en not_active Ceased
- 2020-12-23 MX MX2022007846A patent/MX2022007846A/es unknown
- 2020-12-23 PL PL20830293.5T patent/PL4081511T6/pl unknown
- 2020-12-23 HU HUE20830293A patent/HUE068571T2/hu unknown
- 2020-12-23 EP EP24183456.3A patent/EP4442319A3/en not_active Withdrawn
- 2020-12-23 SI SI202030480T patent/SI4081511T2/sl unknown
- 2020-12-23 DK DK20830293.5T patent/DK4081511T6/da active
- 2020-12-23 RS RS20241087A patent/RS66019B1/sr unknown
- 2020-12-23 PE PE2022001159A patent/PE20221584A1/es unknown
- 2020-12-23 AU AU2020412853A patent/AU2020412853A1/en active Pending
- 2020-12-23 PH PH1/2022/551546A patent/PH12022551546A1/en unknown
- 2020-12-23 TW TW109145642A patent/TWI891696B/zh active
- 2020-12-23 LT LTEPPCT/GB2020/053357T patent/LT4081511T/lt unknown
- 2020-12-23 KR KR1020227024819A patent/KR20220119425A/ko active Pending
- 2020-12-23 CN CN202080083315.0A patent/CN115066418B/zh active Active
- 2020-12-23 CA CA3280359A patent/CA3280359A1/en active Pending
- 2020-12-23 US US17/787,870 patent/US12617762B2/en active Active
-
2022
- 2022-06-21 JO JOP/2022/0162A patent/JOP20220162A1/ar unknown
- 2022-06-21 CO CONC2022/0008652A patent/CO2022008652A2/es unknown
- 2022-06-21 EC ECSENADI202249370A patent/ECSP22049370A/es unknown
- 2022-06-22 CL CL2022001722A patent/CL2022001722A1/es unknown
-
2025
- 2025-05-07 JP JP2025077120A patent/JP2025131581A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20241378T1 (hr) | Karboksi derivati s protuupalnim svojstvima | |
| JP2022530985A5 (enExample) | ||
| KR102668548B1 (ko) | 의학적 질병의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 화합물 | |
| JP6454448B2 (ja) | ４−アミノ−２−（１Ｈ−ピラゾロ［３，４−ｂ］ピリジン−３−イル）−６−オキソ−６，７−ジヒドロ−５Ｈ−ピロロ［２，３−ｄ］ピリミジン誘導体及び心血管疾患を治療するためのｃＧＭＰモジュレーターとしてのそれぞれの（１Ｈ−インダゾール−３−イル）誘導体 | |
| JP2022530985A (ja) | 炎症性疾患または望ましくない免疫応答に関連する疾患の治療におけるイタコン酸誘導体およびその使用 | |
| KR20230019507A (ko) | Il-17의 조절제로서의 이미다조피리다진 | |
| RU2010153578A (ru) | Иммуноглобулины с двойными вариабельными доменами и их применение | |
| RU2010153580A (ru) | Иммуноглобулины с двумя вариабельными доменами и их применение | |
| RU2012119756A (ru) | Иммуноглобулины с двумя вариабельными доменами и их применение | |
| TW202227389A (zh) | 新穎化合物 | |
| RU2014125220A (ru) | Белки, связывающие интерлейкин-1 | |
| JP2010513283A (ja) | 新規なオキサジアゾール化合物 | |
| RU2012112550A (ru) | Иммуноглобулины с двумя вариабельными доменами и их применение | |
| RU2009136299A (ru) | Новые производные 3-({1,2,4}триазоло{4,3-а}пиридин-7-ил)бензамида | |
| RU2013133811A (ru) | Иммуноглобулины с двойными вариабельными доменами и их применения | |
| RU2015143833A (ru) | СВЯЗЫВАЮЩИЕ БЕЛКИ С ДВОЙНОЙ СПЕЦИФИЧНОСТЬЮ, НАПРАВЛЕННЫЕ ПРОТИВ TNFα | |
| RU2013109275A (ru) | Иммуноглобулины с двумя вариабельными доменами и их применение | |
| WO2022029438A1 (en) | Alpha,beta unsaturated methacrylic esters with anti-inflammatory properties | |
| US20230399289A1 (en) | Itaconic acid derivatives | |
| JP2013512951A (ja) | 新規オキサジアゾール化合物 | |
| KR20100099178A (ko) | Ｐ2ｘ7 조절제로서의 5-옥소-3-피롤리딘카르복스아미드 유도체 | |
| CN115768754B (zh) | 调节nlrp3炎症小体通路的二氢噁唑和硫脲或脲衍生物 | |
| TW201536774A (zh) | 經取代之四氫咔唑及咔唑甲醯胺化合物 | |
| JP2024534111A5 (enExample) | ||
| WO2022229617A1 (en) | 2-methylene-4-oxo-butanoic acid drivatives for the treatment of inflammation |