JP2024534111A5 - - Google Patents
Info
- Publication number
- JP2024534111A5 JP2024534111A5 JP2024510689A JP2024510689A JP2024534111A5 JP 2024534111 A5 JP2024534111 A5 JP 2024534111A5 JP 2024510689 A JP2024510689 A JP 2024510689A JP 2024510689 A JP2024510689 A JP 2024510689A JP 2024534111 A5 JP2024534111 A5 JP 2024534111A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- groups
- alkyl
- halogenated
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110988568 | 2021-08-26 | ||
| CN202110988568.9 | 2021-08-26 | ||
| CN202210633028 | 2022-06-06 | ||
| CN202210633028.3 | 2022-06-06 | ||
| PCT/CN2022/115068 WO2023025277A1 (zh) | 2021-08-26 | 2022-08-26 | 含芳环类生物拮抗剂、其制备方法和应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024534111A JP2024534111A (ja) | 2024-09-18 |
| JP2024534111A5 true JP2024534111A5 (enExample) | 2025-07-18 |
Family
ID=85322470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024510689A Pending JP2024534111A (ja) | 2021-08-26 | 2022-08-26 | 芳香環系を含有する生物アンタゴニスト、その製造方法及び応用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240368123A1 (enExample) |
| EP (1) | EP4393920A4 (enExample) |
| JP (1) | JP2024534111A (enExample) |
| KR (1) | KR20240051999A (enExample) |
| CN (1) | CN117836294A (enExample) |
| AU (1) | AU2022334402A1 (enExample) |
| CA (1) | CA3229397A1 (enExample) |
| MX (1) | MX2024002411A (enExample) |
| TW (1) | TW202328116A (enExample) |
| WO (1) | WO2023025277A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240417395A1 (en) * | 2021-10-21 | 2024-12-19 | Nicoya Therapeutics (Shanghai) Co., Ltd | Dual antagonist and use thereof |
| WO2025094214A1 (en) * | 2023-11-02 | 2025-05-08 | Msn Laboratories Private Limited, R&D Center | Process for the preparation of 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl) benzenesulfonamide and its intermediates thereof |
| IT202400000246A1 (it) * | 2024-01-09 | 2025-07-09 | Procos Spa | Processo per la preparazione di sparsentan |
| WO2026021516A1 (zh) * | 2024-07-25 | 2026-01-29 | 深圳信立泰药业股份有限公司 | 一种取代的血管紧张肽和内皮肽受体拮抗剂及其应用 |
| WO2026067819A1 (zh) * | 2024-09-30 | 2026-04-02 | 江苏豪森药业集团有限公司 | 含芳环类生物拮抗剂在制备治疗或预防肾脏疾病药物中的应用 |
| CN119462631A (zh) * | 2024-10-09 | 2025-02-18 | 广东莱佛士制药技术有限公司 | 一种司巴生坦中间体的合成方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ36394A3 (en) * | 1991-08-19 | 1994-07-13 | Du Pont | Substituted imidazilonone derivatives and pharmaceutical preparations based thereon |
| ID26984A (id) * | 1998-07-06 | 2001-02-22 | Bristol Myers Squibb Co | Senyawa-senyawa sulfonamida sebagai antagonis reseptor angiotensin endotelin ganda |
| US6638937B2 (en) * | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| WO2001044239A2 (en) * | 1999-12-15 | 2001-06-21 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| ES2259909B1 (es) * | 2005-02-28 | 2007-06-16 | Inke, S.A. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de su intermedio de sintesis. |
| EP1996588A4 (en) * | 2006-03-03 | 2011-10-05 | Torrent Pharmaceuticals Ltd | NEW DUAL ACTION RECEPTOR (DARA) ANTAGONISTS OF ATI AND ETA RECEPTORS |
| WO2007109456A2 (en) * | 2006-03-16 | 2007-09-27 | Pharmacopeia, Inc. | Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists |
| JP2009515834A (ja) * | 2006-08-29 | 2009-04-16 | テバ ファーマシューティカル インダストリーズ リミティド | ５−フェニル−１−トリチル−１ｈ−テトラゾールの合成のための方法 |
| JP2011518884A (ja) * | 2008-04-29 | 2011-06-30 | セラヴァンス， インコーポレーテッド | 二重活性抗高血圧剤 |
| WO2010114801A1 (en) | 2009-03-31 | 2010-10-07 | Ligand Pharmaceuticals Inc. | Oral formulations of diphenylsulfonamide endothelin and angiotensin ii receptor agonists to treat elevated blood pressure and diabetic nephropathy |
| WO2010135350A2 (en) * | 2009-05-20 | 2010-11-25 | Pharmacopeia, Llc | Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist |
| CN104761548B (zh) * | 2015-04-27 | 2017-09-12 | 梯尔希（南京）药物研发有限公司 | 一种稳定同位素标记的二苯基磺酰胺类药物的制备方法 |
| BR112018077075A2 (pt) * | 2016-06-29 | 2019-04-30 | Universite De Montreal | heterociclos de biarilmetila |
| JP2019530713A (ja) | 2016-10-13 | 2019-10-24 | レトロフィン， インコーポレイテッド | 腎臓疾患または障害を処置するためのビフェニルスルホンアミド化合物 |
| CN112876424B (zh) * | 2019-11-29 | 2023-06-30 | 上海拓界生物医药科技有限公司 | 血管紧张素ii受体及内皮素受体双重拮抗剂 |
| US20240417395A1 (en) * | 2021-10-21 | 2024-12-19 | Nicoya Therapeutics (Shanghai) Co., Ltd | Dual antagonist and use thereof |
| JP2024178482A (ja) * | 2021-11-15 | 2024-12-25 | 株式会社アークメディスン | 化合物、アンジオテンシンｉｉタイプ１受容体拮抗剤及び医薬組成物 |
-
2022
- 2022-08-26 KR KR1020247009542A patent/KR20240051999A/ko active Pending
- 2022-08-26 JP JP2024510689A patent/JP2024534111A/ja active Pending
- 2022-08-26 CN CN202280056242.5A patent/CN117836294A/zh active Pending
- 2022-08-26 TW TW111132297A patent/TW202328116A/zh unknown
- 2022-08-26 WO PCT/CN2022/115068 patent/WO2023025277A1/zh not_active Ceased
- 2022-08-26 MX MX2024002411A patent/MX2024002411A/es unknown
- 2022-08-26 CA CA3229397A patent/CA3229397A1/en active Pending
- 2022-08-26 US US18/685,883 patent/US20240368123A1/en active Pending
- 2022-08-26 AU AU2022334402A patent/AU2022334402A1/en active Pending
- 2022-08-26 EP EP22860623.2A patent/EP4393920A4/en active Pending
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