|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
EP2364368B1
(en)
|
2008-11-07 |
2014-01-15 |
Sequenta, Inc. |
Methods of monitoring conditions by sequence analysis
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
ES2726702T3
(es)
|
2009-01-15 |
2019-10-08 |
Adaptive Biotechnologies Corp |
Perfilado de la inmunidad adaptativa y métodos para la generación de anticuerpos monoclonales
|
|
WO2010151416A1
(en)
|
2009-06-25 |
2010-12-29 |
Fred Hutchinson Cancer Research Center |
Method of measuring adaptive immunity
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2625189B1
(en)
|
2010-10-01 |
2018-06-27 |
ModernaTX, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
AU2012236099A1
(en)
|
2011-03-31 |
2013-10-03 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
PL3892295T3
(pl)
|
2011-05-24 |
2023-07-24 |
BioNTech SE |
Zindywidualizowane szczepionki przeciwnowotworowe
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
EP2768982A4
(en)
|
2011-10-21 |
2015-06-03 |
Adaptive Biotechnologies Corp |
QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS
|
|
US9824179B2
(en)
|
2011-12-09 |
2017-11-21 |
Adaptive Biotechnologies Corp. |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
CA3018046A1
(en)
|
2011-12-16 |
2013-06-20 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
CA2865575C
(en)
|
2012-02-27 |
2024-01-16 |
Cellular Research, Inc. |
Compositions and kits for molecular counting
|
|
EP3372694A1
(en)
|
2012-03-05 |
2018-09-12 |
Adaptive Biotechnologies Corporation |
Determining paired immune receptor chains from frequency matched subunits
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
WO2013151665A2
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
|
HUE029357T2
(en)
|
2012-05-08 |
2017-02-28 |
Adaptive Biotechnologies Corp |
Preparations and devices for measuring and calibrating amplification distortion in multiplex PCR reactions
|
|
WO2014012051A1
(en)
*
|
2012-07-12 |
2014-01-16 |
Persimmune, Inc. |
Personalized cancer vaccines and adoptive immune cell therapies
|
|
WO2014028429A2
(en)
|
2012-08-14 |
2014-02-20 |
Moderna Therapeutics, Inc. |
Enzymes and polymerases for the synthesis of rna
|
|
LT2901341T
(lt)
*
|
2012-09-28 |
2019-09-25 |
The University Of Connecticut |
Protekcinių vėžio epitopų identifikavimas, skirtas vėžio gydymui
|
|
EP3330384B1
(en)
|
2012-10-01 |
2019-09-25 |
Adaptive Biotechnologies Corporation |
Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
|
|
WO2015160439A2
(en)
|
2014-04-17 |
2015-10-22 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
PL2922554T3
(pl)
|
2012-11-26 |
2022-06-20 |
Modernatx, Inc. |
Na zmodyfikowany na końcach
|
|
EP3417874B1
(en)
*
|
2012-11-28 |
2024-09-11 |
BioNTech SE |
Individualized vaccines for cancer
|
|
WO2014093186A1
(en)
*
|
2012-12-12 |
2014-06-19 |
Garvin Alex M |
Non-invasive detection of colorectal neoplasia using circular consensus sequencing
|
|
EP4414990A3
(en)
|
2013-01-17 |
2024-11-06 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
EP2968391A1
(en)
|
2013-03-13 |
2016-01-20 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
|
WO2014152211A1
(en)
|
2013-03-14 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
KR20150132479A
(ko)
*
|
2013-03-15 |
2015-11-25 |
어댑티브 바이오테크놀로지스 코포레이션 |
복합 유전자 세트에서의 독특하게 태그되고 재배열된 적응 면역 수용체 유전자
|
|
EP2983702A2
(en)
*
|
2013-04-07 |
2016-02-17 |
The Broad Institute, Inc. |
Compositions and methods for personalized neoplasia vaccines
|
|
WO2014180490A1
(en)
*
|
2013-05-10 |
2014-11-13 |
Biontech Ag |
Predicting immunogenicity of t cell epitopes
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
US20160186260A1
(en)
*
|
2013-07-26 |
2016-06-30 |
Sequenta, Llc |
Cancer vaccination with antigen evolution
|
|
KR102758333B1
(ko)
|
2013-08-28 |
2025-01-23 |
벡톤 디킨슨 앤드 컴퍼니 |
대량의 동시 단일 세포 분석
|
|
WO2015031689A1
(en)
|
2013-08-30 |
2015-03-05 |
Personalis, Inc. |
Methods and systems for genomic analysis
|
|
WO2015048744A2
(en)
|
2013-09-30 |
2015-04-02 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
WO2015051275A1
(en)
|
2013-10-03 |
2015-04-09 |
Personalis, Inc. |
Methods for analyzing genotypes
|
|
US9582877B2
(en)
|
2013-10-07 |
2017-02-28 |
Cellular Research, Inc. |
Methods and systems for digitally counting features on arrays
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
ES2693217T3
(es)
*
|
2013-12-02 |
2018-12-10 |
Personal Genome Diagnostics Inc. |
Método para evaluar variantes minoritarias en una muestra
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
US20160310584A1
(en)
*
|
2013-12-06 |
2016-10-27 |
The Broad Institute Inc. |
Formulations for neoplasia vaccines
|
|
KR20230076867A
(ko)
|
2013-12-20 |
2023-05-31 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생항원 백신과의 병용 요법
|
|
WO2015134787A2
(en)
|
2014-03-05 |
2015-09-11 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
PL4023249T3
(pl)
|
2014-04-23 |
2025-03-10 |
Modernatx, Inc. |
Szczepionki z kwasem nukleinowym
|
|
US10017759B2
(en)
*
|
2014-06-26 |
2018-07-10 |
Illumina, Inc. |
Library preparation of tagged nucleic acid
|
|
CN113791220A
(zh)
|
2014-09-10 |
2021-12-14 |
豪夫迈·罗氏有限公司 |
免疫原性突变体肽筛选平台
|
|
US11338026B2
(en)
|
2014-09-10 |
2022-05-24 |
The University Of Connecticut |
Identification of immunologically protective neo-epitopes for the treatment of cancers
|
|
JP6599450B2
(ja)
|
2014-10-02 |
2019-10-30 |
アメリカ合衆国 |
がん特異的突然変異に対し抗原特異性を有するt細胞を単離する方法
|
|
CA2966201A1
(en)
|
2014-10-29 |
2016-05-06 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
|
|
US10125399B2
(en)
|
2014-10-30 |
2018-11-13 |
Personalis, Inc. |
Methods for using mosaicism in nucleic acids sampled distal to their origin
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
AU2015353581A1
(en)
|
2014-11-25 |
2017-06-15 |
Adaptive Biotechnologies Corporation |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
|
EP3234130B1
(en)
|
2014-12-19 |
2020-11-25 |
The Broad Institute, Inc. |
Methods for profiling the t-cell- receptor repertoire
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
WO2016128060A1
(en)
*
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
EP3259371B1
(en)
*
|
2015-02-19 |
2020-09-02 |
Becton, Dickinson and Company |
High-throughput single-cell analysis combining proteomic and genomic information
|
|
CA2976580A1
(en)
|
2015-02-24 |
2016-09-01 |
Adaptive Biotechnologies Corp. |
Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
|
|
US10780021B2
(en)
|
2015-02-26 |
2020-09-22 |
Sio2 Medical Products, Inc. |
Cycloolefin polymer container with a scratch resistant and anti-static coating
|
|
WO2016138496A1
(en)
|
2015-02-27 |
2016-09-01 |
Cellular Research, Inc. |
Spatially addressable molecular barcoding
|
|
WO2016160844A2
(en)
|
2015-03-30 |
2016-10-06 |
Cellular Research, Inc. |
Methods and compositions for combinatorial barcoding
|
|
EP3277294B1
(en)
|
2015-04-01 |
2024-05-15 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible t cell receptors specific for an antigenic target
|
|
EP4582556A3
(en)
|
2015-04-23 |
2025-10-08 |
Becton, Dickinson and Company |
Methods and compositions for whole transcriptome amplification
|
|
CN117467603A
(zh)
*
|
2015-04-27 |
2024-01-30 |
癌症研究技术有限公司 |
治疗癌症的方法
|
|
WO2016180467A1
(en)
|
2015-05-11 |
2016-11-17 |
Biontech Cell & Gene Therapies Gmbh |
Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
|
|
EA201792501A1
(ru)
*
|
2015-05-13 |
2018-10-31 |
Эйдженус Инк. |
Вакцины для лечения и профилактики рака
|
|
IL294183B2
(en)
|
2015-05-20 |
2023-10-01 |
Dana Farber Cancer Inst Inc |
shared neoantigens
|
|
WO2016196229A1
(en)
|
2015-06-01 |
2016-12-08 |
Cellular Research, Inc. |
Methods for rna quantification
|
|
TW202241500A
(zh)
*
|
2015-06-09 |
2022-11-01 |
美商博德研究所有限公司 |
用於贅瘤疫苗之調配物及其製備方法
|
|
MA42543A
(fr)
*
|
2015-07-30 |
2018-06-06 |
Modernatx Inc |
Arn épitope peptidiques concatémériques
|
|
GB201516047D0
(en)
|
2015-09-10 |
2015-10-28 |
Cancer Rec Tech Ltd |
Method
|
|
JP6940484B2
(ja)
|
2015-09-11 |
2021-09-29 |
セルラー リサーチ, インコーポレイテッド |
ライブラリー正規化のための方法および組成物
|
|
EP3359670B2
(en)
|
2015-10-05 |
2024-02-14 |
ModernaTX, Inc. |
Methods for therapeutic administration of messenger ribonucleic acid drugs
|
|
WO2017059902A1
(en)
*
|
2015-10-07 |
2017-04-13 |
Biontech Rna Pharmaceuticals Gmbh |
3' utr sequences for stabilization of rna
|
|
EP3362929B1
(en)
|
2015-10-12 |
2020-08-12 |
Nantomics, LLC |
Viral neoepitopes and uses thereof
|
|
MX2018004544A
(es)
|
2015-10-12 |
2018-11-09 |
Nantomics Llc |
Composiciones y métodos para los neoepítopos de cáncer viral.
|
|
AU2016341309A1
(en)
*
|
2015-10-22 |
2018-06-07 |
Modernatx, Inc. |
Cancer vaccines
|
|
ES2970865T3
(es)
|
2015-12-16 |
2024-05-31 |
Gritstone Bio Inc |
Identificación, fabricación y uso de neoantígenos
|
|
CN105349533A
(zh)
*
|
2015-12-21 |
2016-02-24 |
生工生物工程(上海)股份有限公司 |
构建链特异性转录组文库的方法
|
|
EP3400005A1
(en)
*
|
2016-01-08 |
2018-11-14 |
Vaccibody AS |
Neoepitope rna cancer vaccine
|
|
IL260030B2
(en)
|
2016-01-08 |
2025-12-01 |
Nykode Therapeutics ASA |
Therapeutic anticancer neoepitope vaccine
|
|
KR20180117227A
(ko)
|
2016-03-24 |
2018-10-26 |
난트셀, 인크. |
네오에피토프 제시를 위한 시퀀스들 및 시퀀스 배열들
|
|
JP2019513373A
(ja)
|
2016-03-31 |
2019-05-30 |
ネオン セラピューティクス, インコーポレイテッド |
ネオ抗原およびその使用方法
|
|
AU2017254477A1
(en)
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
|
EP3445392A1
(en)
*
|
2016-04-22 |
2019-02-27 |
CureVac AG |
Rna encoding a tumor antigen
|
|
JP7129343B2
(ja)
|
2016-05-02 |
2022-09-01 |
ベクトン・ディキンソン・アンド・カンパニー |
正確な分子バーコーディング
|
|
CN109328070A
(zh)
*
|
2016-05-04 |
2019-02-12 |
免疫疫苗技术有限公司 |
包含两亲化合物、新抗原和疏水载体的疫苗组合物及其使用方法
|
|
WO2017194170A1
(en)
|
2016-05-13 |
2017-11-16 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
ES2979395T3
(es)
|
2016-05-26 |
2024-09-25 |
Becton Dickinson Co |
Métodos de ajuste del recuento de etiquetas moleculares
|
|
CN109890408A
(zh)
*
|
2016-05-27 |
2019-06-14 |
埃特彼塞斯公司 |
新表位疫苗组合物及其使用方法
|
|
US11299783B2
(en)
|
2016-05-27 |
2022-04-12 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
SG11201811258UA
(en)
*
|
2016-07-13 |
2019-01-30 |
Vaximm Ag |
Process for the production of a dna vaccine for cancer immunotherapy
|
|
SG11201900132QA
(en)
*
|
2016-07-20 |
2019-02-27 |
Biontech Rna Pharmaceuticals Gmbh |
Selecting neoepitopes as disease-specific targets for therapy with enhanced efficacy
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
CN109791157B
(zh)
|
2016-09-26 |
2022-06-07 |
贝克顿迪金森公司 |
使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达
|
|
JP7228510B2
(ja)
|
2016-11-08 |
2023-02-24 |
ベクトン・ディキンソン・アンド・カンパニー |
細胞標識分類の方法
|
|
US11164659B2
(en)
|
2016-11-08 |
2021-11-02 |
Becton, Dickinson And Company |
Methods for expression profile classification
|
|
WO2018089637A1
(en)
|
2016-11-11 |
2018-05-17 |
Nantbio, Inc. |
Immunomodulatory compositions, processes for making the same, and methods for inhibiting cytokine storms
|
|
CN108090325B
(zh)
*
|
2016-11-23 |
2022-01-25 |
中国科学院昆明动物研究所 |
一种应用β-稳定性分析单细胞测序数据的方法
|
|
WO2018132753A1
(en)
*
|
2017-01-13 |
2018-07-19 |
Nantbio, Inc. |
Validation of neoepitope-based treatment
|
|
ES2961580T3
(es)
|
2017-01-13 |
2024-03-12 |
Cellular Res Inc |
Revestimiento hidrófilo de canales de fluidos
|
|
WO2018136664A1
(en)
*
|
2017-01-18 |
2018-07-26 |
Ichan School Of Medicine At Mount Sinai |
Neoantigens and uses thereof for treating cancer
|
|
US11549149B2
(en)
|
2017-01-24 |
2023-01-10 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
BR112019015797A2
(pt)
*
|
2017-02-01 |
2020-03-17 |
Modernatx, Inc. |
Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação
|
|
US20190351040A1
(en)
*
|
2017-02-01 |
2019-11-21 |
Modernatx, Inc. |
Rna cancer vaccines
|
|
CN110382708A
(zh)
|
2017-02-01 |
2019-10-25 |
赛卢拉研究公司 |
使用阻断性寡核苷酸进行选择性扩增
|
|
US11965892B2
(en)
|
2017-02-12 |
2024-04-23 |
Biontech Us Inc. |
HLA-based methods and compositions and uses thereof
|
|
US20200101108A1
(en)
|
2017-03-31 |
2020-04-02 |
The Board Of Trustees Of The Le-Land Standford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
|
CA3058807A1
(en)
|
2017-04-03 |
2018-10-11 |
Biontech Us Inc. |
Protein antigens and uses thereof
|
|
US11905525B2
(en)
|
2017-04-05 |
2024-02-20 |
Modernatx, Inc. |
Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
|
|
US11779637B2
(en)
|
2017-04-24 |
2023-10-10 |
Nantcell, Inc. |
Targeted neoepitope vectors and methods therefor
|
|
EP3634449A4
(en)
|
2017-05-08 |
2021-03-17 |
Gritstone Oncology, Inc. |
ALPHAVIRUS NEOANTIGEN VECTORS
|
|
US11464798B2
(en)
|
2017-05-11 |
2022-10-11 |
Theralase Technologies Inc. |
Vaccine containing cancer cells inactivated by photodynamic treatment with metal-based coordination complexes, and immunotherapy method using same
|
|
EP3933408A1
(en)
|
2017-05-30 |
2022-01-05 |
Nant Holdings IP LLC |
Circulating tumor cell enrichment using neoepitopes
|
|
CN110719959B
(zh)
|
2017-06-05 |
2021-08-06 |
贝克顿迪金森公司 |
针对单细胞的样品索引
|
|
WO2018224166A1
(en)
|
2017-06-09 |
2018-12-13 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
|
|
WO2018234506A2
(en)
|
2017-06-21 |
2018-12-27 |
Transgene Sa |
PERSONALIZED VACCINE
|
|
US20200219586A1
(en)
|
2017-06-27 |
2020-07-09 |
Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center |
MHC-1 Genotypes Restricts The Oncogenic Mutational Landscape
|
|
JP7298926B2
(ja)
*
|
2017-07-12 |
2023-06-27 |
ノイスコム アーゲー |
癌の治療のためのネオアンチゲンワクチン組成物
|
|
US10636512B2
(en)
|
2017-07-14 |
2020-04-28 |
Cofactor Genomics, Inc. |
Immuno-oncology applications using next generation sequencing
|
|
EP3688020A4
(en)
|
2017-09-25 |
2021-07-14 |
University of Florida Research Foundation, Incorporated |
IMMUNOASSAYS FOR DETECTION OF RAN PROTEINS
|
|
EP4576103A3
(en)
|
2017-10-10 |
2025-08-27 |
Gritstone bio, Inc. |
Neoantigen identification using hotspots
|
|
CN111630602A
(zh)
*
|
2017-11-22 |
2020-09-04 |
磨石肿瘤生物技术公司 |
减少新抗原的接合表位呈递
|
|
US20200354730A1
(en)
*
|
2017-11-27 |
2020-11-12 |
Nantcell, Inc. |
Improved Yeast Polytope Vaccine Compositions And Methods
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
US20200368336A1
(en)
*
|
2017-12-01 |
2020-11-26 |
Shanghai Jenomed Biotech Co., Ltd. |
Method for preparing personalized cancer vaccine
|
|
TW201930340A
(zh)
|
2017-12-18 |
2019-08-01 |
美商尼恩醫療公司 |
新抗原及其用途
|
|
CA3083792A1
(en)
*
|
2017-12-18 |
2019-06-27 |
Personal Genome Diagnostics Inc. |
Machine learning system and method for somatic mutation discovery
|
|
EP3728636B1
(en)
|
2017-12-19 |
2024-09-11 |
Becton, Dickinson and Company |
Particles associated with oligonucleotides
|
|
MX2020007077A
(es)
|
2018-01-04 |
2020-10-28 |
Iconic Therapeutics Inc |
Anticuerpos anti-factor tisular, conjugados anticuerpo-farmaco y metodos relacionados.
|
|
JP7437310B2
(ja)
*
|
2018-03-14 |
2024-02-22 |
コーニンクレッカ フィリップス エヌ ヴェ |
Rnaシーケンシングデータの転写発現レベルを解釈するために局所的なユニークな特徴を使用するシステム及び方法
|
|
US12462935B2
(en)
*
|
2018-03-30 |
2025-11-04 |
Nucleix Ltd. |
Deep learning-based methods, devices, and systems for prenatal testing
|
|
MA52363A
(fr)
|
2018-04-26 |
2021-03-03 |
Agenus Inc |
Compositions peptidiques de liaison à une protéine de choc thermique (hsp) et leurs méthodes d'utilisation
|
|
JP7358388B2
(ja)
|
2018-05-03 |
2023-10-10 |
ベクトン・ディキンソン・アンド・カンパニー |
反対側の転写物末端における分子バーコーディング
|
|
CN112272710A
(zh)
|
2018-05-03 |
2021-01-26 |
贝克顿迪金森公司 |
高通量多组学样品分析
|
|
IL259392A
(en)
|
2018-05-15 |
2018-08-01 |
Yeda Res & Dev |
Vaccination with cancer neoantigens
|
|
WO2019227106A1
(en)
*
|
2018-05-25 |
2019-11-28 |
The Wistar Institute |
Tumor-specific neoantigens and methods of using the same
|
|
CN108897986B
(zh)
*
|
2018-05-29 |
2020-11-27 |
中南大学 |
一种基于蛋白质信息的基因组序列拼接方法
|
|
US10801064B2
(en)
|
2018-05-31 |
2020-10-13 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
US11814750B2
(en)
|
2018-05-31 |
2023-11-14 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
MX2020014243A
(es)
|
2018-06-19 |
2021-05-12 |
Biontech Us Inc |
Neoantigenos y usos de los mismos.
|
|
AU2019293244B2
(en)
*
|
2018-06-27 |
2026-04-02 |
Modernatx, Inc. |
Personalized cancer vaccine epitope selection
|
|
WO2020020444A1
(en)
*
|
2018-07-24 |
2020-01-30 |
Biontech Rna Pharmaceuticals Gmbh |
Individualized vaccines for cancer
|
|
CA3106564A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for breast cancer
|
|
US20220349010A1
(en)
|
2018-07-26 |
2022-11-03 |
Frame Pharmaceuticals B.V. |
Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database
|
|
MX2021003654A
(es)
|
2018-09-27 |
2021-05-28 |
Nykode Therapeutics AS |
Metodo para seleccionar neoepitopes.
|
|
ES2992135T3
(es)
|
2018-10-01 |
2024-12-09 |
Becton Dickinson Co |
Determinar secuencias de transcripción 5
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
CN114681600A
(zh)
*
|
2018-10-19 |
2022-07-01 |
杭州纽安津生物科技有限公司 |
通用性多肽疫苗及其在制备治疗/预防胰腺癌药物中的应用
|
|
MA54192A
(fr)
*
|
2018-11-07 |
2021-09-15 |
Modernatx Inc |
Vaccins à arn contre le cancer
|
|
US11932849B2
(en)
|
2018-11-08 |
2024-03-19 |
Becton, Dickinson And Company |
Whole transcriptome analysis of single cells using random priming
|
|
MX2021005656A
(es)
*
|
2018-11-15 |
2021-07-07 |
Nouscom Ag |
Seleccion de mutaciones de cancer para la generacion de una vacuna contra cancer personalizada.
|
|
US11492660B2
(en)
|
2018-12-13 |
2022-11-08 |
Becton, Dickinson And Company |
Selective extension in single cell whole transcriptome analysis
|
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
KR20240091046A
(ko)
*
|
2018-12-21 |
2024-06-21 |
바이오엔테크 유에스 인크. |
Hla 클래스 ii-특이적 에피토프 예측 및 cd4+ t 세포 특징화를 위한 방법 및 시스템
|
|
GB201821205D0
(en)
*
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy
|
|
GB201821207D0
(en)
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy therapy
|
|
AU2020207053B2
(en)
*
|
2019-01-08 |
2025-07-31 |
Caris Mpi, Inc. |
Genomic profiling similarity
|
|
AU2020208193A1
(en)
*
|
2019-01-14 |
2021-07-29 |
BioNTech SE |
Methods of treating cancer with a PD-1 axis binding antagonist and an RNA vaccine
|
|
US11371076B2
(en)
|
2019-01-16 |
2022-06-28 |
Becton, Dickinson And Company |
Polymerase chain reaction normalization through primer titration
|
|
ES2945227T3
(es)
|
2019-01-23 |
2023-06-29 |
Becton Dickinson Co |
Oligonucleótidos asociados con anticuerpos
|
|
CN113396230A
(zh)
|
2019-02-08 |
2021-09-14 |
豪夫迈·罗氏有限公司 |
癌症的诊断和治疗方法
|
|
WO2020167920A1
(en)
|
2019-02-14 |
2020-08-20 |
Cellular Research, Inc. |
Hybrid targeted and whole transcriptome amplification
|
|
EP3923979A1
(en)
*
|
2019-02-15 |
2021-12-22 |
Rjan Holding AB |
Autologous cancer tumour associated extrachromosomal circular dna for use as a therapeutic vaccine
|
|
EP3930755A4
(en)
*
|
2019-03-01 |
2023-03-22 |
Flow Pharma Inc. |
DESIGN, MANUFACTURE AND USE OF PERSONALIZED CANCER VACCINES
|
|
US20220154180A1
(en)
|
2019-03-13 |
2022-05-19 |
Toyobo Co., Ltd. |
Production and amplification of nucleic acids
|
|
US11965208B2
(en)
|
2019-04-19 |
2024-04-23 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
CN112011833B
(zh)
*
|
2019-05-30 |
2024-04-26 |
上海桀蒙生物技术有限公司 |
筛选和分离肿瘤新生抗原的方法
|
|
MX2021014525A
(es)
|
2019-05-30 |
2022-03-17 |
Gritstone Bio Inc |
Adenovirus modificados.
|
|
CN120099137A
(zh)
|
2019-07-22 |
2025-06-06 |
贝克顿迪金森公司 |
单细胞染色质免疫沉淀测序测定
|
|
CN110277135B
(zh)
*
|
2019-08-10 |
2021-06-01 |
杭州新范式生物医药科技有限公司 |
一种基于预期疗效选择个体化肿瘤新抗原的方法和系统
|
|
TWI793451B
(zh)
*
|
2019-09-20 |
2023-02-21 |
納維再生科技股份有限公司 |
個人化癌症免疫治療
|
|
WO2021055880A1
(en)
*
|
2019-09-20 |
2021-03-25 |
University Of Florida Researchfoundation, Incorporated |
Detection of antibodies against ran proteins from serum and tissue lysates
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
JP7470787B2
(ja)
|
2019-11-05 |
2024-04-18 |
パーソナリス,インコーポレイティド |
単一試料からの腫瘍純度の推定
|
|
JP7522189B2
(ja)
|
2019-11-08 |
2024-07-24 |
ベクトン・ディキンソン・アンド・カンパニー |
免疫レパートリーシーケンシングのための完全長v(d)j情報を得るためのランダムプライミングの使用
|
|
CN112795647B
(zh)
*
|
2019-11-14 |
2022-08-16 |
北京肿瘤医院(北京大学肿瘤医院) |
一种肿瘤标志物及其应用
|
|
WO2021119505A1
(en)
|
2019-12-13 |
2021-06-17 |
Genentech, Inc. |
Anti-ly6g6d antibodies and methods of use
|
|
WO2021146219A1
(en)
|
2020-01-13 |
2021-07-22 |
Becton, Dickinson And Company |
Cell capture using du-containing oligonucleotides
|
|
US11649497B2
(en)
|
2020-01-13 |
2023-05-16 |
Becton, Dickinson And Company |
Methods and compositions for quantitation of proteins and RNA
|
|
WO2021155057A1
(en)
|
2020-01-29 |
2021-08-05 |
Becton, Dickinson And Company |
Barcoded wells for spatial mapping of single cells through sequencing
|
|
WO2021173719A1
(en)
|
2020-02-25 |
2021-09-02 |
Becton, Dickinson And Company |
Bi-specific probes to enable the use of single-cell samples as single color compensation control
|
|
US20230114434A1
(en)
|
2020-03-13 |
2023-04-13 |
Codiak Biosciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
|
JP2023518414A
(ja)
|
2020-03-20 |
2023-05-01 |
コディアック バイオサイエンシーズ, インコーポレイテッド |
治療のための細胞外小胞
|
|
US11920202B2
(en)
|
2020-04-09 |
2024-03-05 |
University Of Connecticut |
Unbiased identification of tumor rejection mediating neoepitopes
|
|
US11661625B2
(en)
|
2020-05-14 |
2023-05-30 |
Becton, Dickinson And Company |
Primers for immune repertoire profiling
|
|
WO2021242793A2
(en)
|
2020-05-26 |
2021-12-02 |
The Broad Institute, Inc. |
Nucleic acid artificial mini-proteome libraries
|
|
US12157913B2
(en)
|
2020-06-02 |
2024-12-03 |
Becton, Dickinson And Company |
Oligonucleotides and beads for 5 prime gene expression assay
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
US12391940B2
(en)
|
2020-07-31 |
2025-08-19 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
CN116438308A
(zh)
|
2020-08-06 |
2023-07-14 |
磨石生物公司 |
多表位疫苗盒
|
|
WO2022036146A1
(en)
|
2020-08-12 |
2022-02-17 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
GB2613718A
(en)
*
|
2020-08-31 |
2023-06-14 |
World Biotech Regenerative Medical Group Ltd |
Personalized immunogenic compositions and methods for producing and using same
|
|
US20240082389A1
(en)
|
2020-09-23 |
2024-03-14 |
Lonza Sales Ag |
Methods of producing extracellular vesicles
|
|
US11161892B1
(en)
|
2020-12-07 |
2021-11-02 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
US11421015B2
(en)
|
2020-12-07 |
2022-08-23 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
EP4247967A1
(en)
|
2020-11-20 |
2023-09-27 |
Becton, Dickinson and Company |
Profiling of highly expressed and lowly expressed proteins
|
|
CN116710115A
(zh)
|
2020-11-20 |
2023-09-05 |
思维疗法股份有限公司 |
用于优化的肽疫苗的组合物和方法
|
|
US11058751B1
(en)
|
2020-11-20 |
2021-07-13 |
Think Therapeutics, Inc. |
Compositions for optimized RAS peptide vaccines
|
|
JP2024501482A
(ja)
|
2020-12-14 |
2024-01-12 |
ビオンテック ユーエス インコーポレイテッド |
がん免疫療法のための組織特異的抗原
|
|
CN116685850A
(zh)
|
2020-12-15 |
2023-09-01 |
贝克顿迪金森公司 |
单细胞分泌组分析
|
|
US11464842B1
(en)
|
2021-04-28 |
2022-10-11 |
Think Therapeutics, Inc. |
Compositions and method for optimized peptide vaccines using residue optimization
|
|
WO2023025404A1
(en)
|
2021-08-24 |
2023-03-02 |
BioNTech SE |
In vitro transcription technologies
|
|
WO2023059654A1
(en)
|
2021-10-05 |
2023-04-13 |
Personalis, Inc. |
Customized assays for personalized cancer monitoring
|
|
EP4426829A1
(en)
|
2021-11-01 |
2024-09-11 |
Dana-Farber Cancer Institute, Inc. |
Biologically selected nucleic acid artificial mini-proteome libraries
|
|
CN118318038A
(zh)
|
2021-11-10 |
2024-07-09 |
东洋纺株式会社 |
改良的文库制备方法
|
|
CN114181287B
(zh)
*
|
2021-12-10 |
2023-09-19 |
商丘美兰生物工程有限公司 |
一种dna病毒疫苗的制备方法
|
|
CN114350800B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Sphk1在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
CN114410778B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Pf543在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
KR20230130804A
(ko)
*
|
2022-03-04 |
2023-09-12 |
(주)큐리진 |
순환종양세포 검출을 위한 아데노바이러스 5/3 형
|
|
EP4253550A1
(en)
|
2022-04-01 |
2023-10-04 |
GenCC GmbH 6 Co. KG |
Method for the manufacture of a viral system, a vector system or any transport system for cancer-specific crispr complexes
|
|
WO2023209068A1
(en)
|
2022-04-28 |
2023-11-02 |
Carbocalyx Gmbh |
Personalized anticancer vaccine comprising glycoengineered tumour cells or tumour cell fragments
|
|
WO2024015892A1
(en)
|
2022-07-13 |
2024-01-18 |
The Broad Institute, Inc. |
Hla-ii immunopeptidome methods and systems for antigen discovery
|
|
WO2024064931A1
(en)
*
|
2022-09-23 |
2024-03-28 |
BioNTech SE |
Compositions for delivery of liver stage antigens and related methods
|
|
WO2024063788A1
(en)
*
|
2022-09-23 |
2024-03-28 |
BioNTech SE |
Compositions for delivery of malaria antigens and related methods
|
|
WO2024083345A1
(en)
|
2022-10-21 |
2024-04-25 |
BioNTech SE |
Methods and uses associated with liquid compositions
|
|
CN120584195A
(zh)
|
2023-01-26 |
2025-09-02 |
东洋纺株式会社 |
源自核糖体rna的逆转录的抑制
|
|
WO2024231973A1
(ja)
*
|
2023-05-08 |
2024-11-14 |
株式会社日立製作所 |
情報処理装置
|
|
US12531162B1
(en)
*
|
2023-05-31 |
2026-01-20 |
Northeastern University |
Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net
|
|
EP4736848A1
(en)
|
2023-06-28 |
2026-05-06 |
Shanghai Regenelead Therapies Co., Ltd. |
Pharmaceutical composition containing cationic lipid and use thereof
|
|
WO2025024337A1
(en)
*
|
2023-07-24 |
2025-01-30 |
BioNTech SE |
Compositions for delivery of plasmodium antigens and related methods
|
|
WO2025064850A1
(en)
*
|
2023-09-22 |
2025-03-27 |
BioNTech SE |
Rna constructs with n-terminal degrons to enhance an immune response
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
US12562256B2
(en)
*
|
2023-11-07 |
2026-02-24 |
New York University |
Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy
|
|
WO2025146078A1
(en)
*
|
2024-01-04 |
2025-07-10 |
Everest Medicines (China) Co., Ltd. |
Cancer vaccines and uses thereof
|
|
WO2025191449A1
(en)
|
2024-03-11 |
2025-09-18 |
Instadeep Ltd |
Systems and methods for machine learning-based genome annotation
|
|
WO2025202937A1
(en)
|
2024-03-26 |
2025-10-02 |
BioNTech SE |
Cancer vaccines
|
|
WO2025207807A1
(en)
*
|
2024-03-27 |
2025-10-02 |
The University Of Florida Research Foundation, Inc. |
Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer
|
|
WO2025257735A1
(en)
|
2024-06-10 |
2025-12-18 |
BioNTech SE |
Systems and methods for machine learning model-based prediction of immune response
|
|
CN119049567B
(zh)
*
|
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2025-07-22 |
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