|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
CA1327358C
(en)
|
1987-11-17 |
1994-03-01 |
Morio Fujiu |
Fluoro cytidine derivatives
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
CA2309535A1
(en)
|
1997-11-12 |
1999-05-20 |
Brigham And Women's Hospital, Inc. |
The translation enhancer element of the human amyloid precursor protein gene
|
|
CA2398790A1
(en)
|
2000-01-28 |
2001-08-02 |
The Scripps Research Institute |
Methods of identifying synthetic transcriptional and translational regulatory elements, and compositions relating to same
|
|
US7468275B2
(en)
|
2000-01-28 |
2008-12-23 |
The Scripps Research Institute |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
EP2447370B1
(en)
|
2001-09-28 |
2018-07-18 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
MicroRNA molecules
|
|
WO2004041203A2
(en)
|
2002-11-04 |
2004-05-21 |
Xenoport, Inc. |
Gemcitabine prodrugs, pharmaceutical compositions and uses thereof
|
|
US7683036B2
(en)
|
2003-07-31 |
2010-03-23 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
|
|
ES2333724T3
(es)
|
2003-09-26 |
2010-02-26 |
Merck Serono Sa |
Secuencias lideres para uso en la produccion de proteinas.
|
|
EP2479254A1
(en)
|
2005-08-24 |
2012-07-25 |
The Scripps Research Institute |
Translation enhancer-element dependent vector systems
|
|
US7670840B2
(en)
|
2006-01-05 |
2010-03-02 |
The Ohio State University Research Foundation |
Micro-RNA expression abnormalities of pancreatic, endocrine and acinar tumors
|
|
EP1969147B1
(en)
|
2006-01-05 |
2014-07-30 |
The Ohio State University Research Foundation |
microRNA-based methods for the diagnosis of stomach cancer
|
|
EP2522746B1
(en)
|
2006-03-02 |
2014-11-12 |
The Ohio State University Research Foundation |
MicroRNA expression profile associated with pancreatic cancer
|
|
US20090131348A1
(en)
|
2006-09-19 |
2009-05-21 |
Emmanuel Labourier |
Micrornas differentially expressed in pancreatic diseases and uses thereof
|
|
US8252538B2
(en)
|
2006-11-01 |
2012-08-28 |
The Ohio State University |
MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma
|
|
WO2008073915A2
(en)
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
Micrornas differentially expressed in leukemia and uses thereof
|
|
WO2008147974A1
(en)
|
2007-05-23 |
2008-12-04 |
University Of South Florida |
Micro-rnas modulating immunity and inflammation
|
|
US20090099034A1
(en)
|
2007-06-07 |
2009-04-16 |
Wisconsin Alumni Research Foundation |
Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers
|
|
CN101918594A
(zh)
|
2007-11-30 |
2010-12-15 |
俄亥俄州立大学研究基金会 |
肺癌中外周血中的微rna表达特征谱和靶向
|
|
SG10201408162PA
(en)
|
2007-12-11 |
2015-01-29 |
Scripps Research Inst |
Compositions and methods related to mrna translational enhancer elements
|
|
EP2260110B1
(en)
|
2008-02-08 |
2014-11-12 |
Asuragen, INC. |
miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
|
|
CA2717026A1
(en)
|
2008-02-28 |
2009-09-03 |
The Ohio State University Research Foundation |
Microrna signatures associated with human chronic lymphocytic leukemia (ccl) and uses thereof
|
|
EP2112235A1
(en)
|
2008-04-24 |
2009-10-28 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for microRNA expression profiling of nasopharyngeal carcinoma
|
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
|
WO2010018563A2
(en)
|
2008-08-12 |
2010-02-18 |
Rosetta Genomics Ltd. |
Compositions and methods for the prognosis of lymphoma
|
|
US9074206B2
(en)
|
2008-11-13 |
2015-07-07 |
Fudan University |
Compositions and methods for micro-RNA expression profiling of colorectal cancer
|
|
EP2358902A1
(en)
|
2008-12-10 |
2011-08-24 |
Universität Regensburg |
Compositions and methods for micro-rna expression profiling of cancer stem cells
|
|
EP2427574A2
(en)
|
2009-05-08 |
2012-03-14 |
The Ohio State University Research Foundation |
Microrna expression profiling and targeting in chronic obstructive pulmonary disease (copd) lung tissue and methods of use thereof
|
|
WO2011076143A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expression profiling of lung cancer
|
|
WO2011076142A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expession profiling in plasma of colorectal cancer
|
|
EP2341145A1
(en)
|
2009-12-30 |
2011-07-06 |
febit holding GmbH |
miRNA fingerprint in the diagnosis of diseases
|
|
WO2011094683A2
(en)
|
2010-01-29 |
2011-08-04 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Method of identifying myelodysplastic syndromes
|
|
EP2354246A1
(en)
|
2010-02-05 |
2011-08-10 |
febit holding GmbH |
miRNA in the diagnosis of ovarian cancer
|
|
US20130059015A1
(en)
|
2010-03-11 |
2013-03-07 |
H. Lee Moffitt Cancer Center & Research Institute |
Human Cancer micro-RNA Expression Profiles Predictive of Chemo-Response
|
|
WO2011157294A1
(en)
|
2010-06-16 |
2011-12-22 |
Universita' Degli Studi Di Padova |
Compositions for use in treating or preventing cancer, breast cancer, lung cancer, ovarian cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto
|
|
US20130230884A1
(en)
|
2010-07-16 |
2013-09-05 |
John Chaput |
Methods to Identify Synthetic and Natural RNA Elements that Enhance Protein Translation
|
|
WO2012151212A1
(en)
|
2011-05-01 |
2012-11-08 |
University Of Rochester |
Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof
|
|
EP2705370A2
(en)
|
2011-05-06 |
2014-03-12 |
Xentech |
Markers for cancer prognosis and therapy and methods of use
|
|
DK2732052T3
(en)
|
2011-07-15 |
2017-02-20 |
Leo Pharma As |
Diagnostic microRNA profiling in cutaneous T cell lymphoma (CTCL)
|
|
EP2751292A4
(en)
|
2011-09-01 |
2015-05-20 |
Allegro Diagnostics Corp |
METHOD AND COMPOSITIONS FOR DETECTING CANCER BASED ON MIRNA EXPRESSION PROFILES
|
|
EP2758436B1
(en)
|
2011-09-23 |
2019-06-12 |
Universität Stuttgart |
Serum half-life extension using immunoglobulin binding domains
|
|
US20140243240A1
(en)
|
2011-10-26 |
2014-08-28 |
Georgetown University |
microRNA EXPRESSION PROFILING OF THYROID CANCER
|
|
WO2013103659A1
(en)
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
|
PL2922554T3
(pl)
|
2012-11-26 |
2022-06-20 |
Modernatx, Inc. |
Na zmodyfikowany na końcach
|
|
EP3053585A1
(en)
|
2013-12-13 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Alternative nucleic acid molecules and uses thereof
|
|
WO2015196118A1
(en)
|
2014-06-19 |
2015-12-23 |
Moderna Therapeutics, Inc. |
Alternative nucleic acid molecules and uses thereof
|
|
CN108064176A
(zh)
*
|
2015-04-22 |
2018-05-22 |
库瑞瓦格股份公司 |
用于治疗肿瘤疾病的含有rna的组合物
|
|
SI3458083T1
(sl)
|
2016-05-18 |
2023-03-31 |
Modernatx, Inc. |
Polinukleotidi, ki kodirajo interlevkin-12 (IL12) in njihova uporaba
|
|
CN109715205A
(zh)
*
|
2016-08-19 |
2019-05-03 |
库瑞瓦格股份公司 |
用于癌症治疗的rna
|
|
TW202428301A
(zh)
|
2017-02-28 |
2024-07-16 |
法商賽諾菲公司 |
治療性rna
|
|
JP7285220B2
(ja)
*
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|
|
WO2020123716A1
(en)
*
|
2018-12-11 |
2020-06-18 |
Obsidian Therapeutics, Inc. |
Membrane bound il12 compositions and methods for tunable regulation
|