JP2024517884A5 - - Google Patents

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Publication number
JP2024517884A5
JP2024517884A5 JP2023568469A JP2023568469A JP2024517884A5 JP 2024517884 A5 JP2024517884 A5 JP 2024517884A5 JP 2023568469 A JP2023568469 A JP 2023568469A JP 2023568469 A JP2023568469 A JP 2023568469A JP 2024517884 A5 JP2024517884 A5 JP 2024517884A5
Authority
JP
Japan
Prior art keywords
sequence
amino acid
seq
polypeptide chain
chain contains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023568469A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024517884A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/028066 external-priority patent/WO2022236050A1/en
Publication of JP2024517884A publication Critical patent/JP2024517884A/ja
Publication of JP2024517884A5 publication Critical patent/JP2024517884A5/ja
Pending legal-status Critical Current

Links

JP2023568469A 2021-05-07 2022-05-06 p53におけるC135Y、R175H又はM237I変異を認識するT細胞受容体 Pending JP2024517884A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163185805P 2021-05-07 2021-05-07
US63/185,805 2021-05-07
PCT/US2022/028066 WO2022236050A1 (en) 2021-05-07 2022-05-06 T cell receptors recognizing c135y, r175h, or m237i mutation in p53

Publications (2)

Publication Number Publication Date
JP2024517884A JP2024517884A (ja) 2024-04-23
JP2024517884A5 true JP2024517884A5 (https=) 2025-05-20

Family

ID=81851071

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023568469A Pending JP2024517884A (ja) 2021-05-07 2022-05-06 p53におけるC135Y、R175H又はM237I変異を認識するT細胞受容体

Country Status (8)

Country Link
US (1) US20240254190A1 (https=)
EP (1) EP4334340A1 (https=)
JP (1) JP2024517884A (https=)
KR (1) KR20240016288A (https=)
CN (1) CN117957245A (https=)
AU (1) AU2022268998A1 (https=)
CA (1) CA3217263A1 (https=)
WO (1) WO2022236050A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202525841A (zh) 2019-06-27 2025-07-01 美國衛生與公眾服務部 識別p53中之r175h或y220c突變之t細胞受體
WO2024146936A1 (en) * 2023-01-06 2024-07-11 Immunocore Limited Binding molecules against a piwil1 peptide-hla complex
WO2024163371A1 (en) * 2023-01-30 2024-08-08 Fred Hutchinson Cancer Center Binding proteins specific for mutant p53 and uses thereof
WO2024206274A2 (en) * 2023-03-27 2024-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors targeting y220c or r175h mutation in p53
WO2025024648A2 (en) * 2023-07-25 2025-01-30 Memorial Sloan-Kettering Cancer Center T cell receptors targeting tp53 hotspot mutations and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034334B2 (en) 2002-09-06 2011-10-11 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy
US8383099B2 (en) 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
US20120244133A1 (en) 2011-03-22 2012-09-27 The United States of America, as represented by the Secretary, Department of Health and Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
US11390921B2 (en) * 2014-04-01 2022-07-19 Adaptive Biotechnologies Corporation Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
MX375379B (es) 2014-05-29 2025-03-06 Us Health Receptores de celulas t anti - papilomavirus 16 e7 humano.
SG11202002635RA (en) * 2017-09-29 2020-04-29 The United States Of America As Represented By The Secretary Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation
WO2019067243A1 (en) * 2017-09-29 2019-04-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T CELL RECEPTORS RECOGNIZING P53 MUTE
US20220175899A1 (en) * 2019-04-11 2022-06-09 The Board Of Trustees Of The Leland Stanford Junior University Cytotoxic t lymphocytes specific for mutated forms of epidermal growth factor receptor for use in treating cancer
TW202525841A (zh) * 2019-06-27 2025-07-01 美國衛生與公眾服務部 識別p53中之r175h或y220c突變之t細胞受體

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