JP2021524247A5 - - Google Patents

Info

Publication number
JP2021524247A5
JP2021524247A5 JP2020565264A JP2020565264A JP2021524247A5 JP 2021524247 A5 JP2021524247 A5 JP 2021524247A5 JP 2020565264 A JP2020565264 A JP 2020565264A JP 2020565264 A JP2020565264 A JP 2020565264A JP 2021524247 A5 JP2021524247 A5 JP 2021524247A5
Authority
JP
Japan
Prior art keywords
sequence
antigen
nucleic acid
vector
optionally
Prior art date
Application number
JP2020565264A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019226939A5 (https=
JP2021524247A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/033828 external-priority patent/WO2019226939A1/en
Publication of JP2021524247A publication Critical patent/JP2021524247A/ja
Publication of JP2021524247A5 publication Critical patent/JP2021524247A5/ja
Publication of JPWO2019226939A5 publication Critical patent/JPWO2019226939A5/ja
Withdrawn legal-status Critical Current

Links

JP2020565264A 2018-05-23 2019-05-23 免疫チェックポイント阻害剤の共発現ベクター Withdrawn JP2021524247A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862675624P 2018-05-23 2018-05-23
US62/675,624 2018-05-23
PCT/US2019/033828 WO2019226939A1 (en) 2018-05-23 2019-05-23 Immune checkpoint inhibitor co-expression vectors

Publications (3)

Publication Number Publication Date
JP2021524247A JP2021524247A (ja) 2021-09-13
JP2021524247A5 true JP2021524247A5 (https=) 2022-05-27
JPWO2019226939A5 JPWO2019226939A5 (https=) 2022-05-27

Family

ID=68617211

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020565264A Withdrawn JP2021524247A (ja) 2018-05-23 2019-05-23 免疫チェックポイント阻害剤の共発現ベクター

Country Status (9)

Country Link
US (2) US20210213122A1 (https=)
EP (1) EP3796930A4 (https=)
JP (1) JP2021524247A (https=)
KR (1) KR20210013589A (https=)
CN (1) CN112351793A (https=)
AU (1) AU2019275070A1 (https=)
CA (1) CA3099642A1 (https=)
TW (1) TW202000906A (https=)
WO (1) WO2019226939A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105190656B (zh) 2013-01-17 2018-01-16 佩索纳里斯公司 用于遗传分析的方法和系统
US10125399B2 (en) 2014-10-30 2018-11-13 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
MX2019013259A (es) 2017-05-08 2020-01-13 Gritstone Oncology Inc Vectores de neoantigeno de alfavirus.
IL280890B2 (en) * 2018-08-17 2025-10-01 Gritstone Bio Inc Antigen-binding protein that targets shared antigens
EP3877531A4 (en) * 2018-11-07 2022-08-31 Gritstone bio, Inc. ALPHAVIRUS NEOANTIGEN VECTORS AND INTERFERON INHIBITORS
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
MX2021014525A (es) 2019-05-30 2022-03-17 Gritstone Bio Inc Adenovirus modificados.
EP4055610A4 (en) 2019-11-05 2023-11-29 Personalis, Inc. ESTIMATION OF TUMOR PURITY FROM SINGLE SAMPLES
KR20220115569A (ko) 2019-11-18 2022-08-17 얀센 바이오테크 인코포레이티드 돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
EP4168569A4 (en) * 2020-06-18 2024-08-07 Personalis, Inc. Machine-learning techniques for predicting surface-presenting peptides
US12295997B2 (en) 2020-07-06 2025-05-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
KR20230046313A (ko) 2020-08-06 2023-04-05 그릿스톤 바이오, 인코포레이티드 다중에피토프 백신 카세트
CA3216276A1 (en) 2021-04-29 2022-11-03 Yardena Samuels T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same
WO2023034881A1 (en) * 2021-09-02 2023-03-09 Elixirgen Therapeutics, Inc. Temperature-controllable, rna immunotherapeutic for cancer
EP4413580A4 (en) 2021-10-05 2025-08-13 Personalis Inc PERSONALIZED TESTS FOR PERSONALIZED CANCER MONITORING

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0803573A1 (en) * 1996-04-25 1997-10-29 Gesellschaft für Biotechnologische Forschung mbH (GBF) Polycistronic expression construct with cytokines for multivalent vaccines
AU2002242016A1 (en) * 2001-02-01 2002-08-12 The Johns Hopkins University Nucleic acid derived vaccine that encodes an antigen linked to a polypeptide that promotes antigen presentation
CN1561389A (zh) * 2001-07-25 2005-01-05 纽约大学 糖基神经酰胺作为用于抗传染病和癌症的疫苗的佐剂的用途
WO2004031210A2 (en) * 2002-10-03 2004-04-15 Epimmune Inc. Optimized multi-epitope constructs and uses thereof
US9402888B2 (en) * 2013-03-14 2016-08-02 The Wistar Institute Of Anatomy And Biology Methods and compositions for treating cancer
EP3082853A2 (en) * 2013-12-20 2016-10-26 The Broad Institute, Inc. Combination therapy with neoantigen vaccine
MX2017002890A (es) * 2014-09-03 2017-11-13 Bavarian Nordic As Métodos y composiciones para potenciar respuestas inmunitarias.
AU2016339924B2 (en) * 2015-10-12 2020-01-02 Nantomics, Llc Compositions and methods for viral cancer neoepitopes
AU2017225787B2 (en) * 2016-03-03 2021-09-23 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
AU2017226199A1 (en) * 2016-03-04 2018-09-13 New York University Virus vectors expressing multiple epitopes of tumor associated antigens for inducing antitumor immunity
CA3022267A1 (en) * 2016-05-04 2017-11-09 Fred Hutchinson Cancer Research Center Cell-based neoantigen vaccines and uses thereof
PE20191345A1 (es) * 2016-11-23 2019-09-30 Gritstone Oncology Inc Administracion viral de neoantigenos
WO2018161092A1 (en) * 2017-03-03 2018-09-07 New York University Induction and enhancement of antitumor immunity involving virus vectors expressing multiple epitopes of tumor associated antigens and immune checkpoint inhibitors or proteins

Similar Documents

Publication Publication Date Title
JP2021524247A5 (https=)
JP2021525076A5 (https=)
RU2019119272A (ru) Вирусная доставка неоантигенов
JPWO2019226941A5 (https=)
JPWO2019226939A5 (https=)
JP2021501572A5 (https=)
CN111328420B (zh) 用于预防和治疗微卫星不稳定(msi)癌症的基于共有肿瘤新抗原的通用疫苗
JP2021524247A (ja) 免疫チェックポイント阻害剤の共発現ベクター
CN118576699A (zh) Hbv疫苗
JPWO2020243719A5 (https=)
JPS61143327A (ja) 多効果免疫性蛋白質
JP5148116B2 (ja) 癌胎児性抗原融合タンパク質及びその使用
CN118414426A (zh) 产生环状rna的单罐法
JPWO2021236854A5 (https=)
JP2004501646A5 (https=)
JPWO2020097393A5 (https=)
CN115942942A (zh) 感染性疾病抗原和疫苗
RU2019112725A (ru) Композиции и способы для повышения стабильности трансгенов в поксвирусах
EP4038222A1 (en) Methods and compositions for identifying neoantigens for use in treating and preventing cancer
JPWO2022032196A5 (https=)
CN117587070A (zh) 一种经遗传修饰的非人哺乳动物的制备方法及应用
US20070104685A1 (en) Synthetic gene encoding human carcinoembryonic antigen and uses thereof
JPWO2021216776A5 (https=)
CN119770633A (zh) 一种改进型多肽肿瘤疫苗组成与应用
US20080138354A1 (en) Cytomegalovirus vaccine