JP2023521436A5 - - Google Patents

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Publication number
JP2023521436A5
JP2023521436A5 JP2022562684A JP2022562684A JP2023521436A5 JP 2023521436 A5 JP2023521436 A5 JP 2023521436A5 JP 2022562684 A JP2022562684 A JP 2022562684A JP 2022562684 A JP2022562684 A JP 2022562684A JP 2023521436 A5 JP2023521436 A5 JP 2023521436A5
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JP
Japan
Prior art keywords
cells
engineered
cancer
sirpg
manipulated
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022562684A
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English (en)
Japanese (ja)
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JP2023521436A (ja
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Publication date
Priority claimed from GBGB2005599.2A external-priority patent/GB202005599D0/en
Application filed filed Critical
Publication of JP2023521436A publication Critical patent/JP2023521436A/ja
Publication of JP2023521436A5 publication Critical patent/JP2023521436A5/ja
Pending legal-status Critical Current

Links

JP2022562684A 2020-04-17 2021-04-16 T細胞細胞傷害性の調節および関連療法 Pending JP2023521436A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2005599.2 2020-04-17
GBGB2005599.2A GB202005599D0 (en) 2020-04-17 2020-04-17 Modulation of t cell cytotoxicity and related therapy
PCT/EP2021/059989 WO2021209627A1 (en) 2020-04-17 2021-04-16 Modulation of t cell cytotoxicity and related therapy

Publications (2)

Publication Number Publication Date
JP2023521436A JP2023521436A (ja) 2023-05-24
JP2023521436A5 true JP2023521436A5 (https=) 2024-04-26

Family

ID=70859980

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022562684A Pending JP2023521436A (ja) 2020-04-17 2021-04-16 T細胞細胞傷害性の調節および関連療法

Country Status (12)

Country Link
US (1) US20230158073A1 (https=)
EP (1) EP4135725A1 (https=)
JP (1) JP2023521436A (https=)
KR (1) KR20230004643A (https=)
CN (1) CN115697357A (https=)
AU (1) AU2021255917A1 (https=)
BR (1) BR112022020819A2 (https=)
CA (1) CA3175622A1 (https=)
GB (1) GB202005599D0 (https=)
IL (1) IL297309A (https=)
MX (1) MX2022012924A (https=)
WO (1) WO2021209627A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022061115A1 (en) * 2020-09-18 2022-03-24 Vor Biopharma Inc. Compositions and methods for cd7 modification
CN115058504B (zh) * 2022-07-14 2025-07-04 广州医科大学 膀胱癌th17 cd4+t细胞亚群及其特征基因与应用
WO2025063257A1 (ja) * 2023-09-22 2025-03-27 国立大学法人大阪大学 制御性t細胞を製造する方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
KR20140004174A (ko) 2011-01-18 2014-01-10 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 암 치료를 위한 조성물 및 방법
CN103946952A (zh) 2011-09-16 2014-07-23 宾夕法尼亚大学董事会 用于治疗癌症的rna改造的t细胞
WO2014055657A1 (en) 2012-10-05 2014-04-10 The Trustees Of The University Of Pennsylvania Use of a trans-signaling approach in chimeric antigen receptors
KR20170068504A (ko) * 2014-10-08 2017-06-19 노파르티스 아게 키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도
JP7237449B2 (ja) * 2015-02-27 2023-03-13 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体(CARs)の構成およびその使用方法
KR102546839B1 (ko) * 2016-08-03 2023-06-23 워싱턴 유니버시티 키메라 항원 수용체를 이용한 t 세포 악성종양의 치료를 위한 car-t 세포의 유전자 편집
WO2018106972A1 (en) * 2016-12-07 2018-06-14 La Jolla Institute For Allergy And Immunology Compositions for cancer treatment and methods and uses for cancer treatment and prognosis
WO2018183921A1 (en) * 2017-04-01 2018-10-04 The Broad Institute, Inc. Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer
EP3622092A4 (en) * 2017-05-11 2021-06-23 The Broad Institute, Inc. METHODS AND COMPOSITIONS OF USE OF CD8 + TUMOR-INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF
CN110944652A (zh) * 2017-06-12 2020-03-31 爱莫里大学 T细胞抗原靶向的嵌合抗原受体(car)以及在细胞疗法中的用途

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