JP2022079484A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2022079484A5 JP2022079484A5 JP2022035111A JP2022035111A JP2022079484A5 JP 2022079484 A5 JP2022079484 A5 JP 2022079484A5 JP 2022035111 A JP2022035111 A JP 2022035111A JP 2022035111 A JP2022035111 A JP 2022035111A JP 2022079484 A5 JP2022079484 A5 JP 2022079484A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- cells
- preparation
- rpe cells
- human rpe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 27
- 101000670189 Homo sapiens Ribulose-phosphate 3-epimerase Proteins 0.000 claims 19
- 239000000825 pharmaceutical preparation Substances 0.000 claims 9
- 238000000338 in vitro Methods 0.000 claims 6
- 201000007737 Retinal degeneration Diseases 0.000 claims 3
- 108091008695 photoreceptors Proteins 0.000 claims 3
- 230000004258 retinal degeneration Effects 0.000 claims 3
- 108050002823 Bestrophin Proteins 0.000 claims 2
- 102000012304 Bestrophin Human genes 0.000 claims 2
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 2
- 101150092239 OTX2 gene Proteins 0.000 claims 2
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 2
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 2
- 210000001671 embryonic stem cell Anatomy 0.000 claims 2
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 2
- 208000002780 macular degeneration Diseases 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 2
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 208000035719 Maculopathy Diseases 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 108060007030 Ribulose-phosphate 3-epimerase Proteins 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024205622A JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99866807P | 2007-10-12 | 2007-10-12 | |
| US99876607P | 2007-10-12 | 2007-10-12 | |
| US60/998,766 | 2007-10-12 | ||
| US60/998,668 | 2007-10-12 | ||
| US991108P | 2008-01-02 | 2008-01-02 | |
| US990808P | 2008-01-02 | 2008-01-02 | |
| US61/009,908 | 2008-01-02 | ||
| US61/009,911 | 2008-01-02 | ||
| JP2020072683A JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020072683A Division JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024205622A Division JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022079484A JP2022079484A (ja) | 2022-05-26 |
| JP2022079484A5 true JP2022079484A5 (OSRAM) | 2022-11-10 |
Family
ID=40567677
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528899A Withdrawn JP2011500024A (ja) | 2007-10-12 | 2008-10-10 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2022035111A Pending JP2022079484A (ja) | 2007-10-12 | 2022-03-08 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528899A Withdrawn JP2011500024A (ja) | 2007-10-12 | 2008-10-10 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Rpe細胞を生成する改良された方法およびrpe細胞の組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110274662A1 (OSRAM) |
| EP (2) | EP3636748A1 (OSRAM) |
| JP (6) | JP2011500024A (OSRAM) |
| KR (2) | KR101849329B1 (OSRAM) |
| CN (2) | CN101878295A (OSRAM) |
| AU (1) | AU2008312007A1 (OSRAM) |
| CA (3) | CA2702386C (OSRAM) |
| DK (1) | DK2209888T3 (OSRAM) |
| ES (1) | ES2764473T3 (OSRAM) |
| IL (4) | IL292561A (OSRAM) |
| PL (1) | PL2209888T3 (OSRAM) |
| PT (1) | PT2209888T (OSRAM) |
| WO (1) | WO2009051671A1 (OSRAM) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| WO2005070011A2 (en) | 2004-01-23 | 2005-08-04 | Advanced Cell Technology, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| US9133435B2 (en) | 2007-01-18 | 2015-09-15 | Riken | Method for induction/differentiation into photoreceptor cell |
| KR101849329B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Rpe 세포의 개선된 생산 방법 및 rpe 세포의 조성물 |
| EP2279247B1 (en) * | 2008-04-22 | 2019-01-02 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| WO2009148170A1 (ja) | 2008-06-06 | 2009-12-10 | 独立行政法人理化学研究所 | 幹細胞の培養方法 |
| JP5885255B2 (ja) * | 2009-08-28 | 2016-03-15 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | 罹患組織における遺伝的変異の同定 |
| ES2619564T3 (es) | 2009-11-05 | 2017-06-26 | Riken | Un método de inducción de diferenciación de células madre cultivadas |
| EP2501802A4 (en) | 2009-11-17 | 2013-08-21 | Advanced Cell Tech Inc | METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS |
| JP5815552B2 (ja) | 2009-12-08 | 2015-11-17 | ケース ウェスタン リザーブ ユニバーシティCase Westernreserve University | 眼疾患を治療する化合物および方法 |
| EP2596119B8 (en) | 2010-07-23 | 2021-06-02 | Astellas Institute for Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| FI20106354A0 (fi) * | 2010-12-20 | 2010-12-20 | Suomen Punainen Risti Veripalvelu | Menetelmä ihmisen retinan pigmentti-epiteelisolujen valmistamiseksi |
| SG194843A1 (en) | 2011-05-18 | 2013-12-30 | Univ California | Compositions and methods for treating retinal diseases |
| WO2013074681A1 (en) * | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| JP6067232B2 (ja) * | 2011-11-25 | 2017-01-25 | 住友化学株式会社 | 網膜層特異的神経細胞を製造する方法 |
| CN103998599A (zh) * | 2011-11-25 | 2014-08-20 | 住友化学株式会社 | 制备视网膜组织和视网膜相关细胞的方法 |
| JP5985208B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜組織の製造方法 |
| JP6012164B2 (ja) * | 2011-11-25 | 2016-10-25 | 住友化学株式会社 | 多能性幹細胞由来の組織の凍結保存方法 |
| JP5985209B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 眼杯様構造体の製造方法 |
| JP5985207B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜色素上皮細胞の製造方法 |
| WO2013082543A1 (en) | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| HK1208054A1 (en) | 2012-07-12 | 2016-02-19 | 爱姆斯坦生物技术公司 | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN105101979B (zh) | 2012-12-21 | 2021-10-08 | 安斯泰来再生医药协会 | 由多能干细胞制备血小板的方法及其组合物 |
| WO2014121077A2 (en) | 2013-02-01 | 2014-08-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
| WO2014162040A1 (en) * | 2013-04-03 | 2014-10-09 | Tampereen Yliopisto | Methods and media for differentiating eye cells |
| EP3037524B8 (en) | 2013-08-23 | 2020-03-04 | Sumitomo Chemical Company, Limited | Method for producing retinal tissue and retina-related cells |
| HK1221734A1 (zh) | 2013-12-11 | 2017-06-09 | 辉瑞有限公司 | 产生视网膜色素上皮细胞的方法 |
| TWI810142B (zh) | 2014-10-24 | 2023-08-01 | 日商住友製藥股份有限公司 | 神經組織的製造方法 |
| TWI694150B (zh) | 2014-10-24 | 2020-05-21 | 日商大日本住友製藥股份有限公司 | 網膜組織的製造方法 |
| CA2970748C (en) * | 2014-12-18 | 2023-05-09 | Universite Pierre Et Marie Curie (Paris 6) | Transgenic rpe cells overexpressing otx2 for the treatment of retinal degeneration |
| SG11201705379VA (en) | 2014-12-30 | 2017-08-30 | Cell Cure Neurosciences Ltd | Rpe cell populations and methods of generating same |
| ES2843626T3 (es) * | 2014-12-30 | 2021-07-19 | Cell Cure Neurosciences Ltd | Métodos de tratamiento de enfermedades retinianas |
| AU2016235176B2 (en) | 2015-03-23 | 2022-05-19 | Astellas Institute For Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (RPE) cells and photoreceptor progenitors |
| TWI833293B (zh) * | 2015-08-18 | 2024-02-21 | 美商安斯泰來再生醫藥協會 | 臨床調配物 |
| ES2970537T3 (es) | 2015-09-08 | 2024-05-29 | Us Health | Método para la diferenciación reproducible de células epiteliales del pigmento retiniano de calidad clínica |
| AU2016318774B2 (en) * | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| CA2998091C (en) | 2015-09-08 | 2024-06-11 | Sumitomo Dainippon Pharma Co., Ltd. | Method for producing retinal tissue |
| WO2017070337A1 (en) | 2015-10-20 | 2017-04-27 | Cellular Dynamics International, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| PL3368661T3 (pl) * | 2015-10-26 | 2025-07-21 | Cell Cure Neurosciences Ltd. | Przygotowywanie komórek nabłonka barwnikowego siatkówki |
| SG11201809201UA (en) | 2016-04-22 | 2018-11-29 | Sumitomo Dainippon Pharma Co Ltd | Method for producing retinal tissue |
| CA3028613A1 (en) * | 2016-06-30 | 2018-01-04 | Sumitomo Dainippon Pharma Co., Ltd. | Transplantation medium |
| MA47106A (fr) | 2016-12-21 | 2019-10-30 | Amgen Inc | Formulations d'anticorps anti-tnf alpha |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| WO2018195175A1 (en) | 2017-04-18 | 2018-10-25 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| US12090252B2 (en) | 2017-09-14 | 2024-09-17 | Riken | Method for producing retinal tissues |
| CN107760649B (zh) * | 2017-11-02 | 2021-03-30 | 北京全式金生物技术有限公司 | 一种用于人神经系统细胞培养和人多能性干细胞向神经系统细胞分化的营养添加剂 |
| KR102198942B1 (ko) * | 2019-07-02 | 2021-01-05 | 의료법인 성광의료재단 | Pedf를 발현하거나 모세포에 비하여 pedf를 과발현하도록 유전적으로 조작된 중간엽 줄기세포 |
| JP7344421B2 (ja) * | 2019-07-19 | 2023-09-14 | 東京エレクトロン株式会社 | 細胞の分化状態の評価方法 |
| AU2020374884A1 (en) | 2019-10-30 | 2022-06-09 | Astellas Institute For Regenerative Medicine | Methods for producing retinal pigment epithelium cells |
| WO2022191216A1 (ja) | 2021-03-09 | 2022-09-15 | 国立研究開発法人理化学研究所 | 低免疫原性網膜色素上皮細胞の製造方法 |
| US20250188412A1 (en) | 2022-03-16 | 2025-06-12 | Sumitomo Pharma Co., Ltd. | Transplantation medium |
| KR20250007548A (ko) | 2022-04-15 | 2025-01-14 | 아스펜 뉴로사이언스 인코포레이티드 | 세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 |
| JPWO2024172043A1 (OSRAM) | 2023-02-14 | 2024-08-22 | ||
| CN119020271B (zh) * | 2024-07-17 | 2025-06-06 | 中国农业大学 | 一种提高卵子体外成熟质量及体外受精后胚胎妊娠率的组合物、方法及其应用 |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610753A (en) | 1991-12-12 | 1997-03-11 | Eastman Kodak Company | Optical design of laser scanner to reduce thermal sensitivity |
| EP0700429B1 (en) | 1993-04-30 | 2000-10-11 | PHOTOGENESIS Incorporated | Retinal pigment epithelium transplantation |
| DE19609838A1 (de) | 1996-03-13 | 1997-09-18 | Boehringer Mannheim Gmbh | Verfahren und Teststreifen zur Bestimmung eines Analyten |
| US6878544B2 (en) | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
| US20040086494A1 (en) | 1996-10-07 | 2004-05-06 | John Constance Mary | Immune privileged cells for delivery of proteins and peptides |
| EP0986635A4 (en) * | 1997-01-10 | 2001-11-07 | Life Technologies Inc | SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS |
| US6331406B1 (en) | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| WO1999012572A1 (en) | 1997-09-10 | 1999-03-18 | University Of Florida | Compounds and method for the prevention and treatment of diabetic retinopathy |
| JP2002500202A (ja) | 1998-01-02 | 2002-01-08 | タイタン ファーマシューティカルズ, インコーポレイテッド | 免疫優位部位の生成のための色素性網膜上皮細胞の使用 |
| AU2884499A (en) | 1998-03-02 | 1999-09-20 | Compucyte Corp. | Selective cell analysis |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| MXPA02004233A (es) | 1999-10-28 | 2004-02-17 | Univ Massachusetts | Produccion ginogenetica o androgenetica de celulas pluripotentes y lineas celulares, y uso de las mismas para producir celulas diferenciadas y tejidos. |
| WO2001050848A2 (en) | 2000-01-07 | 2001-07-19 | Oregon Health And Science University | Clonal propagation of primate offspring by embryo splitting |
| US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| US20030084471A1 (en) | 2000-03-16 | 2003-05-01 | David Beach | Methods and compositions for RNA interference |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| US20040053869A1 (en) | 2000-08-19 | 2004-03-18 | Peter Andrews | Stem cell differentiation |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| DE60114229T2 (de) | 2000-11-29 | 2006-07-06 | Allergan, Inc., Irvine | Verhinderung von transplantatabstossung im auge |
| DE10108412B4 (de) | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| WO2002092756A2 (en) | 2001-05-15 | 2002-11-21 | Rappaport Family Institute For Research In The Medical Sciences | Insulin producing cells derived from human embryonic stem cells |
| EP1412479A4 (en) | 2001-07-12 | 2004-07-28 | Geron Corp | CELLS WITH CARDIOMYOCYTE GENERATION PRODUCED FROM HUMAN PLURIPOTENT STEM CELLS |
| US20030232430A1 (en) | 2001-11-26 | 2003-12-18 | Advanced Cell Technology | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| US7033831B2 (en) | 2001-12-07 | 2006-04-25 | Geron Corporation | Islet cells from human embryonic stem cells |
| WO2003049773A1 (en) | 2001-12-11 | 2003-06-19 | Fibrogen, Inc. | Methods for inhibiting ocular processes |
| CA2473909A1 (en) | 2002-01-15 | 2003-07-24 | Advanced Cell Technology, Inc. | Cloning b and t lymphocytes |
| JP2006500910A (ja) | 2002-04-18 | 2006-01-12 | アキュイティ ファーマシューティカルズ、インク. | Cnsと眼の標的遺伝子を特異的に調節するための手段と方法及びその同定法 |
| US20040091936A1 (en) | 2002-05-24 | 2004-05-13 | Michael West | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank |
| US7422736B2 (en) * | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| CA2501226A1 (en) | 2002-10-04 | 2004-04-22 | Tissuetech, Inc | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
| US20040133095A1 (en) | 2002-11-14 | 2004-07-08 | Dunki-Jacobs Robert J. | Methods and devices for detecting abnormal tissue cells |
| US20040156878A1 (en) | 2003-02-11 | 2004-08-12 | Alireza Rezania | Implantable medical device seeded with mammalian cells and methods of treatment |
| WO2004106925A2 (en) | 2003-03-03 | 2004-12-09 | Nagaoka & Co.Ltd. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
| WO2004098285A2 (en) | 2003-05-08 | 2004-11-18 | Cellartis Ab | Cryopreservation of human blastocyst-derived stem cells by use of a closed straw vitrification method |
| KR100569168B1 (ko) | 2003-08-08 | 2006-04-07 | (주)아비코아생명공학연구소 | 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포 |
| WO2005070011A2 (en) * | 2004-01-23 | 2005-08-04 | Advanced Cell Technology, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| JP5138367B2 (ja) | 2004-05-07 | 2013-02-06 | ウイスコンシン アラムニ リサーチ ファンデーション | 胚性幹細胞から間葉性幹細胞を形成する方法 |
| US6945971B1 (en) | 2004-07-19 | 2005-09-20 | Gwon Arlene E | Controlled ocular lens regeneration |
| WO2006040763A2 (en) | 2004-10-12 | 2006-04-20 | Technion Research & Development Foundation Ltd. | Isolated primate embryonic cells and methods of generating and using same |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| US7838727B2 (en) | 2004-11-04 | 2010-11-23 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells |
| EP1846548B1 (en) | 2005-02-11 | 2010-09-08 | Agency for Science, Technology and Research | Methods of proliferating stem cells |
| BRPI0612423A2 (pt) | 2005-05-17 | 2009-01-27 | Reliance Life Sciences Pvt Ltd | estabelecimento de linhagem de cÉlulas-tronco embrionÁrias humanas usando cÉlulas de mamÍferos |
| EP1910548A4 (en) | 2005-05-27 | 2010-06-23 | Agency Science Tech & Res | METHOD OF INTRODUCING NUCLEIC ACID MOLECULES IN EMBRYONIC STEM CELLS USING BACULUS VIRUSORS |
| WO2007015252A2 (en) | 2005-08-03 | 2007-02-08 | I.M.T. Interface Multigrad Technology Ltd. | Somatic cells for use in cell therapy |
| JP4926615B2 (ja) | 2006-08-29 | 2012-05-09 | 太陽化学株式会社 | ガラクトマンナン酵素分解物の製造方法 |
| KR100832592B1 (ko) | 2006-08-17 | 2008-05-27 | 박현숙 | 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법 |
| CN101563449A (zh) | 2006-09-22 | 2009-10-21 | 理化学研究所 | 干细胞培养基及干细胞培养方法 |
| EP2886646B1 (en) | 2007-04-18 | 2019-08-14 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| KR101849329B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Rpe 세포의 개선된 생산 방법 및 rpe 세포의 조성물 |
| HU0700675D0 (en) | 2007-10-15 | 2007-12-28 | Mta Tamogatott Kutatohelyek Ir | Method for monitoring stem cell differentiation |
| US20090226955A1 (en) | 2007-12-21 | 2009-09-10 | University Of Miami | Immortalized retinal pigmented epithelial cells |
| US20090233324A1 (en) | 2008-03-11 | 2009-09-17 | Kopf-Sill Anne R | Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location |
| EP2279247B1 (en) * | 2008-04-22 | 2019-01-02 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| US8652123B2 (en) | 2008-09-02 | 2014-02-18 | Geoffrey C. GURTNER | Methods and devices for improving the appearance of tissue |
| EP2501802A4 (en) | 2009-11-17 | 2013-08-21 | Advanced Cell Tech Inc | METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS |
| EP2596119B8 (en) | 2010-07-23 | 2021-06-02 | Astellas Institute for Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| WO2012149484A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| WO2013074681A1 (en) | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| US9458428B2 (en) | 2012-06-05 | 2016-10-04 | The Regents Of The University Of California | Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells |
-
2008
- 2008-10-10 KR KR1020107007791A patent/KR101849329B1/ko active Active
- 2008-10-10 ES ES08839134T patent/ES2764473T3/es active Active
- 2008-10-10 CN CN2008801180610A patent/CN101878295A/zh active Pending
- 2008-10-10 KR KR1020167009962A patent/KR101849336B1/ko active Active
- 2008-10-10 PT PT88391347T patent/PT2209888T/pt unknown
- 2008-10-10 EP EP19196641.5A patent/EP3636748A1/en active Pending
- 2008-10-10 CN CN201510271562.4A patent/CN104946591A/zh active Pending
- 2008-10-10 DK DK08839134.7T patent/DK2209888T3/da active
- 2008-10-10 CA CA2702386A patent/CA2702386C/en active Active
- 2008-10-10 CA CA3177952A patent/CA3177952A1/en active Pending
- 2008-10-10 PL PL08839134T patent/PL2209888T3/pl unknown
- 2008-10-10 EP EP08839134.7A patent/EP2209888B1/en active Active
- 2008-10-10 IL IL292561A patent/IL292561A/en unknown
- 2008-10-10 CA CA3006687A patent/CA3006687C/en active Active
- 2008-10-10 WO PCT/US2008/011669 patent/WO2009051671A1/en not_active Ceased
- 2008-10-10 AU AU2008312007A patent/AU2008312007A1/en not_active Abandoned
- 2008-10-10 US US12/682,712 patent/US20110274662A1/en not_active Abandoned
- 2008-10-10 JP JP2010528899A patent/JP2011500024A/ja not_active Withdrawn
-
2010
- 2010-04-08 IL IL204956A patent/IL204956A/en active IP Right Grant
-
2014
- 2014-04-16 US US14/254,833 patent/US10077424B2/en active Active
- 2014-06-19 JP JP2014125977A patent/JP6137626B2/ja active Active
-
2016
- 2016-06-13 IL IL246181A patent/IL246181A0/en unknown
-
2017
- 2017-04-19 JP JP2017083243A patent/JP6692768B2/ja active Active
-
2018
- 2018-08-27 US US16/113,717 patent/US20190062703A1/en not_active Abandoned
-
2020
- 2020-04-15 JP JP2020072683A patent/JP2020115882A/ja active Pending
-
2021
- 2021-03-29 US US17/216,172 patent/US20220049217A1/en active Pending
-
2022
- 2022-03-08 JP JP2022035111A patent/JP2022079484A/ja active Pending
-
2024
- 2024-11-26 JP JP2024205622A patent/JP2025036424A/ja active Pending
-
2025
- 2025-10-30 IL IL324350A patent/IL324350A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022079484A5 (OSRAM) | ||
| Rossmiller et al. | Gene therapy in animal models of autosomal dominant retinitis pigmentosa | |
| JP2022040140A5 (OSRAM) | ||
| JP2011500024A5 (OSRAM) | ||
| JP2015096556A5 (OSRAM) | ||
| JP7330510B2 (ja) | 非滲出型または萎縮型の黄斑変性にて以前に失われた視力を回復させるための医薬組成物 | |
| CN109937053B (zh) | 用于治疗黄斑变性的含有mTOR抑制剂的药物组合物 | |
| US20250057868A1 (en) | Compositions and methods of modulating hif-2a to improve muscle generation and repair | |
| CN108350458B (zh) | 用豹蛙酶和/或两栖酶治疗病毒性结膜炎 | |
| JP2017523983A5 (OSRAM) | ||
| AU2016390488A1 (en) | Application of dimethylamino micheliolide | |
| CN114983972B (zh) | 水凝胶包被miRNA-200s纳米微粒缓释系统在制备视神经炎疾病类药物中的应用 | |
| CN103356637B (zh) | 毛壳素在制备预防和治疗心脏病药物中的应用 | |
| CN118903383A (zh) | Vegf-b蛋白、vegf-b蛋白活性肽段在制备预防和/或治疗急性前葡萄膜炎的药物中的应用 | |
| WO2017129055A1 (zh) | 一种用于治疗脂肪肝、肝炎、肝硬化的药物 | |
| CN110812368A (zh) | 一种治疗肝脏缺血再灌注损伤的药物组合物及其制备方法 | |
| CN110898062B (zh) | Tak1抑制剂ng25及其衍生物在制备肌营养不良症药物中的应用 | |
| TW201538165A (zh) | 促進幹細胞分化及作爲心肌梗塞癒後保養的活性成分 | |
| CN114469968A (zh) | 一种红景天苷的应用 | |
| CN105267202A (zh) | 升麻素在制药中的应用 | |
| CN106344932A (zh) | 一种用于提高视网膜退行性疾病基因治疗效果的组合物及其应用 | |
| Liang et al. | The roles of nanocarriers on pigment epithelium-derived factor in the differentiation of human cardiac stem cells | |
| CN107184545A (zh) | 一种魔芋葡甘聚糖眼用凝胶剂及其制备方法 | |
| WO2016120647A4 (en) | Muscle regeneration | |
| CN111744005A (zh) | 一种女性下生殖道粘膜保护、再生喷剂及其制备方法 |