SG11201705379VA - Rpe cell populations and methods of generating same - Google Patents
Rpe cell populations and methods of generating sameInfo
- Publication number
- SG11201705379VA SG11201705379VA SG11201705379VA SG11201705379VA SG11201705379VA SG 11201705379V A SG11201705379V A SG 11201705379VA SG 11201705379V A SG11201705379V A SG 11201705379VA SG 11201705379V A SG11201705379V A SG 11201705379VA SG 11201705379V A SG11201705379V A SG 11201705379VA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- cell populations
- rpe cell
- generating same
- generating
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Developmental Biology & Embryology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462097753P | 2014-12-30 | 2014-12-30 | |
| US201562116972P | 2015-02-17 | 2015-02-17 | |
| US201562195309P | 2015-07-22 | 2015-07-22 | |
| PCT/IL2015/051269 WO2016108239A1 (en) | 2014-12-30 | 2015-12-30 | Rpe cell populations and methods of generating same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201705379VA true SG11201705379VA (en) | 2017-08-30 |
Family
ID=55315463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705379VA SG11201705379VA (en) | 2014-12-30 | 2015-12-30 | Rpe cell populations and methods of generating same |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US11891622B2 (en) |
| EP (2) | EP3674397A1 (en) |
| JP (3) | JP6882981B2 (en) |
| KR (1) | KR20170115514A (en) |
| CN (1) | CN107406830A (en) |
| AU (2) | AU2015373050B2 (en) |
| BR (1) | BR112017014345A2 (en) |
| CA (1) | CA2972575A1 (en) |
| DK (1) | DK3240892T5 (en) |
| EA (1) | EA201791416A1 (en) |
| ES (1) | ES2774456T3 (en) |
| HK (1) | HK1246348A1 (en) |
| IL (3) | IL305070A (en) |
| MX (1) | MX2017008737A (en) |
| PH (1) | PH12017501218A1 (en) |
| SG (1) | SG11201705379VA (en) |
| WO (1) | WO2016108239A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102073730B1 (en) | 2009-11-17 | 2020-02-05 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| CN114533761A (en) | 2014-12-30 | 2022-05-27 | 细胞治疗神经科学有限公司 | Methods of treating retinal diseases |
| DK3240892T5 (en) | 2014-12-30 | 2020-10-19 | Cell Cure Neurosciences Ltd | RPE CELL POPULATIONS AND METHODS FOR EACHING THEM |
| EP3240890B1 (en) | 2014-12-30 | 2021-06-16 | Cell Cure Neurosciences Ltd. | Assessing retinal pigment epithelial cell populations |
| AU2016303631B2 (en) * | 2015-08-05 | 2022-07-28 | Cell Cure Neurosciences Ltd. | Preparation of photoreceptors for the treatment of retinal diseases |
| EA201890424A1 (en) * | 2015-08-05 | 2018-06-29 | Селл Кьюр Нейросайансес Лтд. | OBTAINING CELL PIGMENT EPITHELIUM CELLS |
| KR20200031559A (en) * | 2017-03-16 | 2020-03-24 | 리니지 셀 테라퓨틱스, 인크. | How to measure the therapeutic effect of retinal disease therapy |
| CN109957545A (en) | 2017-12-26 | 2019-07-02 | 江苏艾尔康生物医药科技有限公司 | A method of digestion RPE cell |
| US20220259558A1 (en) * | 2019-05-15 | 2022-08-18 | Novo Nordisk A/S | Methods for obtaining eye field progenitor cells from human pluripotent stem cells |
| CN111972399B (en) * | 2020-08-06 | 2021-11-30 | 温州医科大学 | Preservation solution for maintaining activity of liver cells |
| KR20240038013A (en) | 2021-07-28 | 2024-03-22 | 리니지 셀 테라퓨틱스, 인크. | Expansion of retinal pigment epithelial cells |
| CN115840045B (en) * | 2023-02-23 | 2023-04-28 | 中国农业大学 | Identification method of porcine embryonic hair follicle basal plate precursor cells and application thereof |
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| KR20200031559A (en) | 2017-03-16 | 2020-03-24 | 리니지 셀 테라퓨틱스, 인크. | How to measure the therapeutic effect of retinal disease therapy |
| WO2019130061A2 (en) | 2017-12-29 | 2019-07-04 | Cell Cure Neurosciences Ltd. | Retinal pigment epithelium cell compositions |
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-
2015
- 2015-12-30 DK DK15832827.8T patent/DK3240892T5/en active
- 2015-12-30 EP EP19207191.8A patent/EP3674397A1/en active Pending
- 2015-12-30 US US15/539,473 patent/US11891622B2/en active Active
- 2015-12-30 IL IL305070A patent/IL305070A/en unknown
- 2015-12-30 BR BR112017014345-3A patent/BR112017014345A2/en not_active Application Discontinuation
- 2015-12-30 EP EP15832827.8A patent/EP3240892B9/en active Active
- 2015-12-30 EA EA201791416A patent/EA201791416A1/en unknown
- 2015-12-30 WO PCT/IL2015/051269 patent/WO2016108239A1/en active Application Filing
- 2015-12-30 ES ES15832827T patent/ES2774456T3/en active Active
- 2015-12-30 SG SG11201705379VA patent/SG11201705379VA/en unknown
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