JP2021533753A5 - - Google Patents

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Publication number
JP2021533753A5
JP2021533753A5 JP2021506753A JP2021506753A JP2021533753A5 JP 2021533753 A5 JP2021533753 A5 JP 2021533753A5 JP 2021506753 A JP2021506753 A JP 2021506753A JP 2021506753 A JP2021506753 A JP 2021506753A JP 2021533753 A5 JP2021533753 A5 JP 2021533753A5
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nucleic acid
sequence
itr
factor
acid molecule
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JP2021506753A
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JP2021533753A (ja
JP7602454B2 (ja
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Priority claimed from PCT/US2019/045957 external-priority patent/WO2020033863A1/en
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JP2021506753A 2018-08-09 2019-08-09 核酸分子及び非ウイルス遺伝子治療のためのそれらの使用 Active JP7602454B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862716826P 2018-08-09 2018-08-09
US62/716,826 2018-08-09
PCT/US2019/045957 WO2020033863A1 (en) 2018-08-09 2019-08-09 Nucleic acid molecules and uses thereof for non-viral gene therapy

Publications (3)

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JP2021533753A JP2021533753A (ja) 2021-12-09
JP2021533753A5 true JP2021533753A5 (enExample) 2022-08-12
JP7602454B2 JP7602454B2 (ja) 2024-12-18

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JP2021506753A Active JP7602454B2 (ja) 2018-08-09 2019-08-09 核酸分子及び非ウイルス遺伝子治療のためのそれらの使用

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US (2) US12364774B2 (enExample)
EP (1) EP3833766A1 (enExample)
JP (1) JP7602454B2 (enExample)
KR (2) KR102925832B1 (enExample)
CN (2) CN113227385B (enExample)
AU (2) AU2019319984B2 (enExample)
BR (1) BR112021002017A2 (enExample)
CA (1) CA3108799A1 (enExample)
CO (1) CO2021002965A2 (enExample)
IL (1) IL280652A (enExample)
MX (2) MX2021001599A (enExample)
PH (1) PH12021500010A1 (enExample)
SG (1) SG11202101157VA (enExample)
TW (2) TW202547562A (enExample)
WO (1) WO2020033863A1 (enExample)

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JP7602454B2 (ja) 2018-08-09 2024-12-18 バイオベラティブ セラピューティクス インコーポレイテッド 核酸分子及び非ウイルス遺伝子治療のためのそれらの使用
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AU2022334714A1 (en) * 2021-08-23 2024-04-04 Bioverativ Therapeutics Inc. Closed-end dna production with inverted terminal repeat sequences
JP2024532261A (ja) * 2021-08-23 2024-09-05 バイオベラティブ セラピューティクス インコーポレイテッド 操作itr配列および使用方法
CN122521785A (zh) * 2021-09-16 2026-08-07 北京锦篮基因科技股份有限公司 用于治疗ⅱ型粘多糖贮积症的重组腺相关病毒载体及其应用
KR20240067122A (ko) * 2021-09-30 2024-05-16 바이오버라티브 테라퓨틱스 인크. 감소된 면역원성을 갖는 인자 viii 폴리펩타이드를 암호화하는 핵산
CN114250224B (zh) * 2021-12-16 2024-02-27 福建和瑞基因科技有限公司 一种用于提取或检测样本中小分子rna的核酸组合物及其试剂盒和方法
WO2023135273A2 (en) * 2022-01-14 2023-07-20 Anjarium Biosciences Ag Compositions of dna molecules encoding factor viii, methods of making thereof, and methods of use thereof
FR3136367A1 (fr) * 2022-06-09 2023-12-15 Damien SULEIMAN Compositions et méthodes concernant des molécules d’ARN messager codant le facteur V encapsulées dans des nanoparticules lipidiques
CN119233998A (zh) * 2022-07-07 2024-12-31 深圳新诺微环生物科技有限公司 一种连接肽、包含连接肽的凝血八因子蛋白或其变体及其用途
JP2025525583A (ja) 2022-07-19 2025-08-05 ランパート バイオサイエンス インコーポレイテッド 非免疫原性環状非ウイルス性dnaベクター
CN116064673A (zh) * 2022-10-19 2023-05-05 河南省人民医院 表达rs1的重组腺相关病毒载体及其应用
CN120981563A (zh) * 2023-03-24 2025-11-18 南京金斯瑞生物科技有限公司 一种提升质粒稳定性的宿主细胞

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