JP2021529159A5 - - Google Patents

Info

Publication number
JP2021529159A5
JP2021529159A5 JP2020570065A JP2020570065A JP2021529159A5 JP 2021529159 A5 JP2021529159 A5 JP 2021529159A5 JP 2020570065 A JP2020570065 A JP 2020570065A JP 2020570065 A JP2020570065 A JP 2020570065A JP 2021529159 A5 JP2021529159 A5 JP 2021529159A5
Authority
JP
Japan
Prior art keywords
alkyl
haloalkyl
pharmaceutically acceptable
acceptable salt
alkoxyl
Prior art date
Application number
JP2020570065A
Other languages
English (en)
Japanese (ja)
Other versions
JP7328260B2 (ja
JP2021529159A (ja
JPWO2019244047A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/055121 external-priority patent/WO2019244047A1/en
Publication of JP2021529159A publication Critical patent/JP2021529159A/ja
Publication of JP2021529159A5 publication Critical patent/JP2021529159A5/ja
Publication of JPWO2019244047A5 publication Critical patent/JPWO2019244047A5/ja
Application granted granted Critical
Publication of JP7328260B2 publication Critical patent/JP7328260B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020570065A 2018-06-19 2019-06-18 N-置換テトラヒドロチエノピリジン誘導体及びその使用 Active JP7328260B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862687068P 2018-06-19 2018-06-19
US62/687,068 2018-06-19
PCT/IB2019/055121 WO2019244047A1 (en) 2018-06-19 2019-06-18 N-substituted tetrahydrothienopyridine derivatives and uses thereof

Publications (4)

Publication Number Publication Date
JP2021529159A JP2021529159A (ja) 2021-10-28
JP2021529159A5 true JP2021529159A5 (https=) 2022-07-04
JPWO2019244047A5 JPWO2019244047A5 (https=) 2022-07-04
JP7328260B2 JP7328260B2 (ja) 2023-08-16

Family

ID=67841114

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020570065A Active JP7328260B2 (ja) 2018-06-19 2019-06-18 N-置換テトラヒドロチエノピリジン誘導体及びその使用

Country Status (24)

Country Link
US (3) US12012417B2 (https=)
EP (2) EP4169925B1 (https=)
JP (1) JP7328260B2 (https=)
KR (1) KR102835904B1 (https=)
CN (1) CN112313237A (https=)
AU (1) AU2019291488B2 (https=)
BR (1) BR112020025696A2 (https=)
CA (1) CA3100957A1 (https=)
CL (1) CL2020003248A1 (https=)
CR (1) CR20200618A (https=)
CU (1) CU20200100A7 (https=)
EA (1) EA202190046A1 (https=)
EC (1) ECSP20080995A (https=)
ES (2) ES3062606T3 (https=)
IL (1) IL279441B2 (https=)
JO (1) JOP20200326A1 (https=)
MA (1) MA52976A (https=)
MX (1) MX2020013852A (https=)
MY (1) MY201990A (https=)
PE (1) PE20210097A1 (https=)
PH (1) PH12020552185A1 (https=)
SA (1) SA520420809B1 (https=)
SG (1) SG11202012625PA (https=)
WO (1) WO2019244047A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3663299B1 (en) * 2017-08-01 2023-03-08 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Bicyclic compound acting as ror gamma inhibitor
BR112020025696A2 (pt) 2018-06-19 2021-03-16 Novartis Ag Derivados de tetra-hidrotienopiridina n-substituída e usos dos mesmos
USD1006154S1 (en) * 2023-06-27 2023-11-28 Qiongfang Mao Cable crossover attachment
WO2025238553A1 (en) 2024-05-14 2025-11-20 Novartis Ag Dosing regimens for n-(3-cyano-5-(cyclohexylmethyl)-6,6-dimethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-2-(4-sulfamoylphenyl)acetamide for use in treating or preventing a dengue virus disease or disorder
WO2025253267A1 (en) 2024-06-06 2025-12-11 Janssen Pharmaceuticals, Inc. Combination of mosnodenvir and close analogs with nitd-688 for use in the treatment and prevention of dengue disease

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807A (en) 1848-09-26 Brake fob cabs
US6344A (en) 1849-04-17 Driving-bobbin
US498178A (en) 1893-05-23 William valentine leonard
US4656A (en) 1846-07-24 Improvement in potato-plows
US8766A (en) 1852-02-24 Appabatus for lightening vessels
US54472A (en) 1866-05-01 Improved blacking-brush
US6054472A (en) 1996-04-23 2000-04-25 Vertex Pharmaceuticals, Incorporated Inhibitors of IMPDH enzyme
US5807876A (en) 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
CA2252465C (en) 1996-04-23 2007-07-03 Vertex Pharmaceuticals Incorporated Urea derivatives as inhibitors of impdh enzyme
DK0966465T3 (da) 1997-03-14 2003-10-20 Vertex Pharma Inhibitorer af IMPDH-enzymer
CA2367017C (en) 1999-03-19 2009-05-26 Vertex Pharmaceuticals Incorporated Inhibitors of impdh enzyme
GB0114185D0 (en) 2001-06-12 2001-08-01 Protherics Molecular Design Lt Compounds
DE60236428D1 (de) 2001-05-21 2010-07-01 Monsanto Technology Llc Etheramin-tenside enthaltende pestizidkonzentrate
US20030232994A1 (en) 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
CA2498399A1 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
US7138529B2 (en) * 2003-04-16 2006-11-21 Hoffmann-La Roche Inc. Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists
GB0324653D0 (en) 2003-10-22 2003-11-26 Syngenta Participations Ag Fungicides
ES2309765T3 (es) 2004-05-28 2008-12-16 4Sc Ag Tetrahidropiridotiofenos.
AU2005272646A1 (en) 2004-08-12 2006-02-23 Wyeth Combination therapy for diabetes, obesity, and cardiovascular diseases using GDF-8 inhibitors
EP1851229A1 (en) 2005-02-09 2007-11-07 Nycomed GmbH Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
AU2006212179A1 (en) 2005-02-11 2006-08-17 4Sc Ag Tetrahydropyridothiophenes as antripoliferative agents for the treatment of cancer
BRPI0610283A2 (pt) 2005-05-13 2010-10-19 Virochem Pharma Inc composto, uso do mesmo na preparação de um medicamento para o tratamento ou prevenção de uma infecção por vìrus de hepatite c, composição farmacêutica e combinação farmacêutica
US7714136B2 (en) 2005-05-25 2010-05-11 4Sc Ag Tetrahydropyridothiophenes
US7763728B2 (en) 2005-05-25 2010-07-27 4Sc Ag Tetrahydropyridothiophenes
US7932391B2 (en) 2005-09-08 2011-04-26 Zhejiang Hauhai Pharmaceutical Co., Ltd. Method for the preparation of clopidogrel and its analogues of methyl-tetrahydrothieno[3,2-C]pyridine acetate
WO2008020024A1 (en) 2006-08-16 2008-02-21 4Sc Ag Ntetrahydropyridothiophene derivatives for the treatment of cancer
WO2008020045A1 (en) 2006-08-16 2008-02-21 4Sc Ag Tetrahydrobenzothiophene derivatives
WO2008067222A1 (en) 2006-11-28 2008-06-05 Kalypsys, Inc. Heterocyclic modulators of tgr5
CA2709784A1 (en) 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
MX2011008988A (es) 2009-02-27 2011-12-16 Siga Technologies Inc Derivados de tienopiridina para el tratamiento y prevencion de infecciones por el virus del dengue.
US20130129677A1 (en) * 2009-02-27 2013-05-23 Siga Technologies, Inc. Thienopyridine Derivatives for the Treatment and Prevention of Dengue Virus Infections
JP5701655B2 (ja) 2011-03-29 2015-04-15 奈良県 植物精油中のトロポロン類及び/又はフェノール類の金属錯体化方法
AP2014007595A0 (en) 2011-09-30 2014-04-30 Kineta Inc Anti-viral compounds
US10844051B2 (en) 2015-07-22 2020-11-24 The Royal Institution For The Advancement Of Learning/Mcgill University Substituted oxazoles for the treatment of cancer
CN108689987A (zh) * 2017-04-05 2018-10-23 浙江海正药业股份有限公司 一种磺胺类衍生物及其制备方法和用途
CN110753682B (zh) * 2017-05-22 2023-06-30 杨森制药公司 作为登革热病毒复制抑制剂的经取代的吲哚啉衍生物
EP3663299B1 (en) 2017-08-01 2023-03-08 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Bicyclic compound acting as ror gamma inhibitor
CN108191885B (zh) * 2018-01-29 2020-08-04 华东师范大学 一类哌啶并噻吩类小分子有机化合物及其应用
BR112020025696A2 (pt) 2018-06-19 2021-03-16 Novartis Ag Derivados de tetra-hidrotienopiridina n-substituída e usos dos mesmos

Similar Documents

Publication Publication Date Title
JP2021529159A5 (https=)
JP2021088610A5 (https=)
RU2002131941A (ru) 3-азот-6,7-дикислородсодержащие стероиды и их применение
ES2922973T1 (es) Peptidos funcionalizados como agentes antivirales
JP2021513967A5 (https=)
KR930702371A (ko) 뉴클레오시드 유도체
JPWO2022158528A5 (https=)
JP2010539241A5 (https=)
RU2006134020A (ru) Конденсированные производные пиразола
RU2009102252A (ru) Хиноксалинилмакроциклические ингибиторы серинпротеазы вируса гепатита с
RU2003110577A (ru) Гетероциклические соединения, связывающиеся с хемокиновыми рецепторами
JP2007505138A5 (https=)
PE20090630A1 (es) Derivados de indol 2-carboxi sustituidos y metodos para su utilizacion
JP2014503516A5 (https=)
CN116751164A (zh) 蛋白酶抑制剂、其制备和用途
JP2007533740A5 (https=)
RU2006125377A (ru) Гетероциклические ингибиторы аспартилпротеазы
JP2011521903A5 (https=)
RU2008108024A (ru) Ингибиторы серинпротеазы
JPWO2022251502A5 (https=)
JP2020507589A5 (https=)
RU2014113539A (ru) Тетрациклические гетероциклические соединения и способы их применения для лечения вирусных заболеваний
AR116474A1 (es) DERIVADOS DEL ÁCIDO 6,7-DIHIDRO-2H-BENZOFURO[2,3-a]QUINOLIZIN-3-CARBOXÍLICO COMO AGENTES ANTIVIRALES PARA EL TRATAMIENTO O PREVENCIÓN DE UNA INFECCIÓN POR HBV
AR048808A1 (es) Pirrolocarbazoles fusionados
JP2008521908A5 (https=)