AU2007325315A1 - Heterocyclic modulators of TGR5 - Google Patents
Heterocyclic modulators of TGR5Info
- Publication number
- AU2007325315A1 AU2007325315A1 AU2007325315A AU2007325315A AU2007325315A1 AU 2007325315 A1 AU2007325315 A1 AU 2007325315A1 AU 2007325315 A AU2007325315 A AU 2007325315A AU 2007325315 A AU2007325315 A AU 2007325315A AU 2007325315 A1 AU2007325315 A1 AU 2007325315A1
- Authority
- AU
- Australia
- Prior art keywords
- tgr5
- heterocyclic modulators
- modulators
- heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86758306P | 2006-11-28 | 2006-11-28 | |
PCT/US2007/085267 WO2008067222A1 (en) | 2006-11-28 | 2007-11-20 | Heterocyclic modulators of tgr5 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2007325315A1 true AU2007325315A1 (en) | 2008-06-05 |
AU2007325315A8 AU2007325315A8 (en) | 2009-07-09 |
Family
ID=39126169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2007325315A Pending AU2007325315A1 (en) | 2006-11-28 | 2007-11-20 | Heterocyclic modulators of TGR5 |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2007325315A1 (en) |
WO (1) | WO2008067222A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009032754A2 (en) * | 2007-08-31 | 2009-03-12 | Kalypsys, Inc. | Heterocyclodiazepine cannabinoid receptor modulators for treatment of disease |
FR2921658A1 (en) * | 2007-09-27 | 2009-04-03 | Sod Conseils Rech Applic | New pyrazolo-pyrazine derivatives are G protein inhibitors useful for preparing a medicament to treat or prevent disease or disorder e.g. cancer, non-tumor proliferative diseases, neurodegenerative diseases and parasitic diseases |
EP2566860B1 (en) | 2010-05-06 | 2014-09-10 | Bristol-Myers Squibb Company | Bicyclic heteroaryl compounds as gpr119 modulators |
EP2582709B1 (en) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
WO2012149236A1 (en) | 2011-04-28 | 2012-11-01 | Bristol-Myers Squibb Company | Novel bicyclic nitrogen containing heteroaryl tgr5 receptor modulators |
EA201490807A1 (en) | 2011-10-21 | 2014-07-30 | Торрент Фармасьютикалз Лимитед | NEW SUBSTITUTED IMIDAZOPIRIMIDINES AS GPBAR1 MODULATORS |
WO2013102929A1 (en) | 2011-12-26 | 2013-07-11 | Cadila Healthcare Limited | Novel compounds for treatment of diabetes, obesity or related disorders |
WO2013134527A1 (en) * | 2012-03-07 | 2013-09-12 | Rigel Pharmaceuticals, Inc. | Synthesis of polycyclic alkaloids and their use as tgr5 agonists |
WO2014100021A1 (en) | 2012-12-17 | 2014-06-26 | Exelixis, Inc. | Tgr5 agonists: imidazole and triazole compounds containing a quaternary nitrogen |
AU2014306759B2 (en) | 2013-08-12 | 2018-04-26 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
EP3169315B1 (en) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
EP3572411A1 (en) | 2018-05-21 | 2019-11-27 | Antabio SAS | Thiazole derivatives as metallo-beta-lactamase inhibitors |
BR112022006546A2 (en) | 2019-10-07 | 2022-08-30 | Kallyope Inc | GPR119 AGONISTS |
MX2022014505A (en) | 2020-05-19 | 2022-12-13 | Kallyope Inc | Ampk activators. |
CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3934018A (en) * | 1970-09-03 | 1976-01-20 | Abbott Laboratories | 4,6-Dihydro-1,3-dimethyl-8-phenylpyrazolo[4,3-e] [1,4]diazepin-5-(1H)-one and derivatives as anti-inflammatory agents |
EP0315698B1 (en) * | 1987-05-28 | 1993-03-03 | Yoshitomi Pharmaceutical Industries, Ltd. | Thieno(triazolo)diazepine compounds and medicinal application of the same |
WO1994006802A1 (en) * | 1992-09-18 | 1994-03-31 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienodiazepine compound and medicinal use thereof |
JPH11209356A (en) * | 1997-04-21 | 1999-08-03 | Takeda Chem Ind Ltd | Condensed cyclic compound, its production and agent |
FR2791980B1 (en) * | 1999-04-09 | 2001-07-06 | Sod Conseils Rech Applic | PYRIDO-THIENO-DIAZEPINES, THEIR PREPARATION PROCESS, AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
CA2451163A1 (en) * | 2001-06-28 | 2003-01-09 | Takeda Chemical Industries, Ltd. | Agent for preventing or treating organ functional disorders and order dysfunction |
US7625887B2 (en) * | 2003-01-28 | 2009-12-01 | Takeda Pharmaceutical Company Limited | Receptor agonists |
JP4671123B2 (en) * | 2003-06-23 | 2011-04-13 | 小野薬品工業株式会社 | New tricyclic heterocyclic compounds |
JPWO2005068467A1 (en) * | 2004-01-14 | 2007-12-27 | 味の素株式会社 | New condensed ring compounds |
JP2006056881A (en) * | 2004-07-21 | 2006-03-02 | Takeda Chem Ind Ltd | Fused ring compound |
JP2006063064A (en) * | 2004-07-27 | 2006-03-09 | Takeda Chem Ind Ltd | Receptor agonist |
-
2007
- 2007-11-20 AU AU2007325315A patent/AU2007325315A1/en active Pending
- 2007-11-20 WO PCT/US2007/085267 patent/WO2008067222A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2008067222A1 (en) | 2008-06-05 |
AU2007325315A8 (en) | 2009-07-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TH | Corrigenda |
Free format text: IN VOL 23, NO 23, PAGE(S) 8658 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE -NAME INDEX UNDER THE NAME KALYPSYS, INC., DELETE ALL REFERENCE TO APPLICATION NO. 2007325315. |