JP2021519061A5 - - Google Patents
Info
- Publication number
- JP2021519061A5 JP2021519061A5 JP2020551264A JP2020551264A JP2021519061A5 JP 2021519061 A5 JP2021519061 A5 JP 2021519061A5 JP 2020551264 A JP2020551264 A JP 2020551264A JP 2020551264 A JP2020551264 A JP 2020551264A JP 2021519061 A5 JP2021519061 A5 JP 2021519061A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- induced
- cell
- genome
- construct according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024181460A JP2025013853A (ja) | 2018-03-29 | 2024-10-17 | 操作された免疫エフェクター細胞およびその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862649781P | 2018-03-29 | 2018-03-29 | |
| US62/649,781 | 2018-03-29 | ||
| US201862774052P | 2018-11-30 | 2018-11-30 | |
| US62/774,052 | 2018-11-30 | ||
| PCT/US2018/067289 WO2019126748A1 (en) | 2017-12-22 | 2018-12-21 | Enhanced immune effector cells and use thereof |
| USPCT/US2018/067289 | 2018-12-21 | ||
| PCT/US2019/024686 WO2019191495A1 (en) | 2018-03-29 | 2019-03-28 | Engineered immune effector cells and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024181460A Division JP2025013853A (ja) | 2018-03-29 | 2024-10-17 | 操作された免疫エフェクター細胞およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519061A JP2021519061A (ja) | 2021-08-10 |
| JP2021519061A5 true JP2021519061A5 (https=) | 2022-04-04 |
| JP7575271B2 JP7575271B2 (ja) | 2024-10-29 |
Family
ID=68060556
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551264A Active JP7575271B2 (ja) | 2018-03-29 | 2019-03-28 | 操作された免疫エフェクター細胞およびその使用 |
| JP2024181460A Pending JP2025013853A (ja) | 2018-03-29 | 2024-10-17 | 操作された免疫エフェクター細胞およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024181460A Pending JP2025013853A (ja) | 2018-03-29 | 2024-10-17 | 操作された免疫エフェクター細胞およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210024959A1 (https=) |
| EP (1) | EP3775228B1 (https=) |
| JP (2) | JP7575271B2 (https=) |
| KR (2) | KR102817092B1 (https=) |
| CN (1) | CN111954715A (https=) |
| AU (2) | AU2019243315A1 (https=) |
| BR (1) | BR112020019205A2 (https=) |
| CA (1) | CA3093020A1 (https=) |
| IL (1) | IL277611A (https=) |
| MX (1) | MX2020009896A (https=) |
| SG (1) | SG11202008977UA (https=) |
| WO (1) | WO2019191495A1 (https=) |
Families Citing this family (52)
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| WO2021178933A2 (en) | 2020-03-06 | 2021-09-10 | Metagenomi Ip Technologies, Llc | Class ii, type v crispr systems |
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| IL316257A (en) | 2017-12-22 | 2024-12-01 | Fate Therapeutics Inc | Enhanced immune effector cells and use thereof |
| CN110628821B (zh) * | 2018-06-25 | 2022-02-18 | 首都医科大学宣武医院 | 一种细胞模型及其制备方法、应用 |
| CA3110837A1 (en) | 2018-08-28 | 2020-03-05 | Vor Biopharma Inc. | Genetically engineered hematopoietic stem cells and uses thereof |
| JP7595583B2 (ja) * | 2019-04-30 | 2024-12-06 | アタラ バイオセラピューティクス,インコーポレーテッド | 抗原特異的cd19標的化car-t細胞 |
| JP7728747B2 (ja) * | 2019-08-23 | 2025-08-25 | サナ バイオテクノロジー,インコーポレイテッド | Cd24発現細胞およびそれらの用途 |
| EP4041759A4 (en) * | 2019-10-07 | 2023-12-20 | Fate Therapeutics, Inc. | IMPROVED CHIMERIC ANTIGEN RECEPTOR FOR IMMUNE EFFECTOR CELL CULTURE AND USE THEREOF |
| EP4045539A4 (en) * | 2019-10-17 | 2024-03-13 | Fate Therapeutics, Inc. | Enhanced chimeric antigen receptor for immune effector cell engineering and use thereof |
| US20230149511A1 (en) * | 2020-04-09 | 2023-05-18 | Wallkill BioPharma, Inc. | Treating autoimmune diseases with genetically modified cells |
| JP2023524976A (ja) * | 2020-05-04 | 2023-06-14 | エディタス・メディシン、インコーポレイテッド | 必須遺伝子ノックインによる選択 |
| BR112022025806A2 (pt) * | 2020-06-19 | 2023-03-07 | Fate Therapeutics Inc | Combinação de tipos de células efetoras derivadas de ipsc para uso em imunoterapia |
| JP2023541457A (ja) * | 2020-09-14 | 2023-10-02 | ブイオーアール バイオファーマ インコーポレーテッド | Cd38修飾のための化合物および方法 |
| CN114457025A (zh) * | 2020-10-30 | 2022-05-10 | 未来智人再生医学研究院(广州)有限公司 | 一种表达btla阻断物的多能干细胞或其衍生物及应用 |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| KR20230118887A (ko) | 2020-12-03 | 2023-08-14 | 센츄리 쎄라퓨틱스 인코포레이티드 | 유전자 조작 세포 및 이의 용도 |
| CN114107211B (zh) * | 2020-12-04 | 2025-09-30 | 未来智人再生医学研究院(广州)有限公司 | 一种多能干细胞及其衍生物 |
| CN114645018A (zh) * | 2020-12-18 | 2022-06-21 | 未来智人再生医学研究院(广州)有限公司 | 一种表达cd38靶向抑制因子的多能干细胞及其衍生物与应用 |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| CN114657137A (zh) * | 2020-12-22 | 2022-06-24 | 未来智人再生医学研究院(广州)有限公司 | 一种表达靶向BTLA的shRNA和/或shRNA-miR的多能干细胞或其衍生物 |
| CN114657133A (zh) * | 2020-12-22 | 2022-06-24 | 未来智人再生医学研究院(广州)有限公司 | 一种表达靶向IL-4 Rα的shRNA和/或shRNA-miR的多能干细胞 |
| EP4305053A1 (en) * | 2021-03-11 | 2024-01-17 | Kite Pharma, Inc. | Improving immune cell function |
| AU2022271241A1 (en) * | 2021-05-04 | 2023-11-23 | Shoreline Biosciences, Inc. | Engineered cells for therapy |
| BR112023024983A2 (pt) * | 2021-06-02 | 2024-04-30 | Metagenomi Inc | Sistemas crispr classe ii, tipo v |
| US20240316102A1 (en) | 2021-07-01 | 2024-09-26 | Indapta Therapeutics, Inc. | Engineered natural killer (nk) cells and related methods |
| CN113278652B (zh) * | 2021-07-20 | 2021-10-01 | 卡瑞济(北京)生命科技有限公司 | 增加Survivin表达的CAR-T细胞并联合IL-15在制备抗肿瘤药物中的应用 |
| CN115989244A (zh) * | 2021-08-06 | 2023-04-18 | 上海驯鹿生物技术有限公司 | Cd5和cd7双靶点的全人源嵌合抗原受体(car)及其应用 |
| CN117835993A (zh) * | 2021-08-18 | 2024-04-05 | 菲特治疗公司 | 作为单一疗法以及与抗体组合的现成的iPSC衍生的CAR-NK细胞 |
| CN116103239A (zh) * | 2021-11-11 | 2023-05-12 | 南京北恒生物科技有限公司 | 工程化免疫细胞及其用途 |
| CN118284686A (zh) * | 2021-11-24 | 2024-07-02 | 杭州启函生物科技有限公司 | 用于基于细胞的免疫疗法的系统和方法 |
| JP2025501617A (ja) * | 2021-12-24 | 2025-01-22 | ヘマセル バイオテクノロジー インコーポレイテッド | 相同組換え及びインテグラーゼ媒介性組換えによりヒト人工多能性幹細胞を製造する方法 |
| CN116804185A (zh) * | 2022-03-25 | 2023-09-26 | 士泽生物医药(苏州)有限公司 | 一种通用型细胞及其制备方法 |
| US20250228943A1 (en) | 2022-04-08 | 2025-07-17 | Fate Therapeutics, Inc. | Cells having solid tumor targeting backbone and use thereof |
| US20250222029A1 (en) | 2022-04-08 | 2025-07-10 | Fate Therapeutics, Inc. | Chimeric antigen receptor for tumor targeting |
| CN116948012B (zh) * | 2022-04-13 | 2024-07-26 | 星奕昂(上海)生物科技有限公司 | 增强细胞功能的cd16抗剪切突变体 |
| AU2023276763A1 (en) | 2022-05-25 | 2024-12-12 | Metagenomi Therapeutics, Inc. | Supplementation of liver enzyme expression |
| CN114774469B (zh) * | 2022-06-22 | 2022-11-08 | 南京艾尔普再生医学科技有限公司 | 一种adcc功能增强的nk细胞的制作方法、nk细胞及其组合物 |
| JP2025525439A (ja) | 2022-06-30 | 2025-08-05 | インダプタ セラピューティクス インコーポレイテッド | 操作されたナチュラルキラー(nk)細胞と抗体療法との組み合わせおよび関連する方法 |
| WO2024050138A2 (en) * | 2022-09-02 | 2024-03-07 | Myeloid Therapeutics, Inc. | Compositions for cell-specific expression and uses thereof |
| IL319793A (en) * | 2022-09-22 | 2025-05-01 | Myeloid Therapeutics Inc | Engineered chimeric fusion protein compositions and methods for using them |
| WO2024102704A2 (en) * | 2022-11-07 | 2024-05-16 | Fate Therapeutics, Inc. | Ipsc-derived nk cell targeting mica/b for solid tumor treatment |
| WO2024183750A1 (en) * | 2023-03-07 | 2024-09-12 | Qihan Hong Kong Limited | A novel immune cell and use thereof for treating diseases |
| WO2024211852A1 (en) * | 2023-04-07 | 2024-10-10 | Fate Therapeutics, Inc. | Ipsc-derived nk cell for lymphoma treatment |
| AU2024269870A1 (en) * | 2023-05-05 | 2025-11-20 | Board Of Regents, The University Of Texas System | Multi-receptor natural killer cells |
| CN116286905B (zh) * | 2023-05-11 | 2023-08-15 | 内蒙古大学 | 牛源化CRISPR/boCas9基因编辑系统、方法及应用 |
| CN119371550A (zh) * | 2023-08-10 | 2025-01-28 | 深圳市三启生物技术有限公司 | 含有gprc5d抗体的嵌合抗原受体及其应用 |
| WO2025102504A1 (zh) * | 2023-11-15 | 2025-05-22 | 复旦大学 | 基于i型内含子的环状rna制备方法及其应用 |
| WO2025240349A2 (en) * | 2024-05-15 | 2025-11-20 | Be Biopharma, Inc. | Allogeneic cell compositions and methods thereof |
| WO2025257119A1 (en) * | 2024-06-10 | 2025-12-18 | Repairon Immuno Gmbh | Method of producing a modified immune cell from a pluripotent stem cell (psc) |
| CN119264271B (zh) * | 2024-10-08 | 2025-05-09 | 北京市神经外科研究所 | 一种nk细胞特异性的嵌合抗原受体及其应用 |
| CN121159717B (zh) * | 2025-09-11 | 2026-04-21 | 中邦干细胞科技有限公司 | 一种嵌合蛋白、工程化nk细胞及其制备方法和用途 |
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| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
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| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
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| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
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| MX2014001222A (es) | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
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| BR112014029417B1 (pt) | 2012-05-25 | 2023-03-07 | Cellectis | Método ex vivo para a preparação de células t para imunoterapia |
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| IL316257A (en) * | 2017-12-22 | 2024-12-01 | Fate Therapeutics Inc | Enhanced immune effector cells and use thereof |
-
2019
- 2019-03-28 KR KR1020207029206A patent/KR102817092B1/ko active Active
- 2019-03-28 AU AU2019243315A patent/AU2019243315A1/en not_active Abandoned
- 2019-03-28 MX MX2020009896A patent/MX2020009896A/es unknown
- 2019-03-28 EP EP19774331.3A patent/EP3775228B1/en active Active
- 2019-03-28 CN CN201980021676.XA patent/CN111954715A/zh active Pending
- 2019-03-28 CA CA3093020A patent/CA3093020A1/en active Pending
- 2019-03-28 WO PCT/US2019/024686 patent/WO2019191495A1/en not_active Ceased
- 2019-03-28 US US17/040,951 patent/US20210024959A1/en active Pending
- 2019-03-28 SG SG11202008977UA patent/SG11202008977UA/en unknown
- 2019-03-28 BR BR112020019205-8A patent/BR112020019205A2/pt unknown
- 2019-03-28 JP JP2020551264A patent/JP7575271B2/ja active Active
- 2019-03-28 KR KR1020257018081A patent/KR20250084985A/ko active Pending
-
2020
- 2020-09-24 IL IL277611A patent/IL277611A/en unknown
-
2024
- 2024-10-17 JP JP2024181460A patent/JP2025013853A/ja active Pending
-
2025
- 2025-10-24 AU AU2025256224A patent/AU2025256224A1/en active Pending
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