JP2022527405A5 - - Google Patents

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Publication number
JP2022527405A5
JP2022527405A5 JP2021560206A JP2021560206A JP2022527405A5 JP 2022527405 A5 JP2022527405 A5 JP 2022527405A5 JP 2021560206 A JP2021560206 A JP 2021560206A JP 2021560206 A JP2021560206 A JP 2021560206A JP 2022527405 A5 JP2022527405 A5 JP 2022527405A5
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JP
Japan
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JP2021560206A
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Japanese (ja)
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JPWO2020210398A5 (https=
JP2022527405A (ja
JP7783746B2 (ja
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JP2021560206A 2019-04-11 2020-04-08 操作されたiPSCおよび免疫エフェクター細胞におけるCD3の再構成 Active JP7783746B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962832622P 2019-04-11 2019-04-11
US62/832,622 2019-04-11
PCT/US2020/027327 WO2020210398A1 (en) 2019-04-11 2020-04-08 CD3 RECONSTITUTION IN ENGINEERED iPSC AND IMMUNE EFFECTOR CELLS

Publications (4)

Publication Number Publication Date
JP2022527405A JP2022527405A (ja) 2022-06-01
JPWO2020210398A5 JPWO2020210398A5 (https=) 2023-04-18
JP2022527405A5 true JP2022527405A5 (https=) 2023-04-18
JP7783746B2 JP7783746B2 (ja) 2025-12-10

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JP2021560206A Active JP7783746B2 (ja) 2019-04-11 2020-04-08 操作されたiPSCおよび免疫エフェクター細胞におけるCD3の再構成

Country Status (12)

Country Link
US (1) US20220184142A1 (https=)
EP (1) EP3953453A4 (https=)
JP (1) JP7783746B2 (https=)
KR (1) KR20210139472A (https=)
CN (1) CN113906133A (https=)
AU (1) AU2020271523A1 (https=)
BR (1) BR112021019772A2 (https=)
CA (1) CA3135224A1 (https=)
IL (1) IL286858A (https=)
MX (1) MX2021012054A (https=)
SG (1) SG11202110601UA (https=)
WO (1) WO2020210398A1 (https=)

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SG11202104524YA (en) 2018-11-01 2021-05-28 Gracell Biotechnologies Shanghai Co Ltd Compositions and methods for t cell engineering
AU2021292695A1 (en) 2020-06-19 2023-02-02 Fate Therapeutics, Inc. Combining iPSC-derived effector cell types for immunotherapy use
CN114525259B (zh) * 2020-11-03 2025-02-14 南京北恒生物科技有限公司 靶向cd7的嵌合抗原受体及其用途
JP2023548467A (ja) * 2020-11-04 2023-11-17 フェイト セラピューティクス,インコーポレイティド 操作されたiPSC及び持続性免疫エフェクター細胞
JP2023549098A (ja) * 2020-11-04 2023-11-22 フェイト セラピューティクス,インコーポレイティド 固形腫瘍を標的とする多重操作されたiPSC及び免疫エフェクター細胞
US11591381B2 (en) 2020-11-30 2023-02-28 Crispr Therapeutics Ag Gene-edited natural killer cells
AU2021392032A1 (en) 2020-12-03 2023-06-22 Century Therapeutics, Inc. Genetically engineered cells and uses thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
CA3204417A1 (en) * 2021-01-29 2022-08-04 Allogene Therapeutics, Inc. Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products
CN117377756A (zh) * 2021-03-05 2024-01-09 菲克特生物科学股份有限公司 工程化免疫细胞疗法
CN113528453B (zh) * 2021-07-07 2023-05-12 金宇保灵生物药品有限公司 一种永生化猪巨噬细胞株及其构建方法和应用
GB202110363D0 (en) * 2021-07-19 2021-09-01 Celyad S A NKG2D CAR cells expressing IL-18 for adoptive cell therapy
EP4504221A4 (en) * 2022-03-22 2026-02-25 Celyntra Therapeutics Sa Compositions and methods for generating cells with reduced immunogenicity
WO2023233342A2 (en) * 2022-06-01 2023-12-07 Crispr Therapeutics Ag Gene-edited natural killer cells
US20260071238A1 (en) * 2022-09-02 2026-03-12 Janssen Biotech, Inc. Materials and processes for engineering hypoimmunogenicity
WO2025076485A1 (en) * 2023-10-05 2025-04-10 Mink Therapeutics, Inc. Novel invariant natural killer t cells and t cell engager compositions and methods of use thereof

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AU2014248119B2 (en) * 2013-04-03 2019-06-20 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted T-cells derived from pluripotent stem cells
EP3134515B1 (en) 2014-04-24 2019-03-27 Board of Regents, The University of Texas System Application of induced pluripotent stem cells to generate adoptive cell therapy products
WO2016007570A2 (en) * 2014-07-09 2016-01-14 The Regents Of The University Of California Engineered invariant natural killer t (inkt) cells and methods of making and using thereof
GB201506642D0 (en) * 2015-04-20 2015-06-03 Ucl Business Plc T cell receptor
CN117070468A (zh) * 2015-10-05 2023-11-17 精密生物科学公司 包含经修饰的人T细胞受体α恒定区基因的经遗传修饰的细胞
JP6928604B2 (ja) * 2015-11-04 2021-09-01 フェイト セラピューティクス,インコーポレイテッド 万能性細胞のゲノム改変
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