JP2024518011A5 - - Google Patents
Info
- Publication number
- JP2024518011A5 JP2024518011A5 JP2023551146A JP2023551146A JP2024518011A5 JP 2024518011 A5 JP2024518011 A5 JP 2024518011A5 JP 2023551146 A JP2023551146 A JP 2023551146A JP 2023551146 A JP2023551146 A JP 2023551146A JP 2024518011 A5 JP2024518011 A5 JP 2024518011A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- antigen
- receptor
- mam
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163151421P | 2021-02-19 | 2021-02-19 | |
| US63/151,421 | 2021-02-19 | ||
| US202163245181P | 2021-09-16 | 2021-09-16 | |
| US63/245,181 | 2021-09-16 | ||
| PCT/US2022/017177 WO2022178367A2 (en) | 2021-02-19 | 2022-02-21 | Single-chain and multi-chain synthetic antigen receptors for diverse immune cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024518011A JP2024518011A (ja) | 2024-04-24 |
| JP2024518011A5 true JP2024518011A5 (https=) | 2025-04-10 |
Family
ID=82932320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023551146A Pending JP2024518011A (ja) | 2021-02-19 | 2022-02-21 | 多様な免疫細胞のための単鎖および多鎖合成抗原受容体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240390496A1 (https=) |
| EP (1) | EP4297769A4 (https=) |
| JP (1) | JP2024518011A (https=) |
| KR (1) | KR20230153529A (https=) |
| AU (1) | AU2022224066A1 (https=) |
| CA (1) | CA3208717A1 (https=) |
| IL (1) | IL305175A (https=) |
| WO (1) | WO2022178367A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3428194T (lt) | 2017-07-14 | 2021-12-10 | Immatics Biotechnologies Gmbh | Pagerinta dvejopo savitumo polipeptido molekulė |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| JP7599205B2 (ja) * | 2018-06-01 | 2024-12-13 | アンヘレス セラピューティクス インコーポレイテッド | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| US12595311B2 (en) | 2020-03-02 | 2026-04-07 | The Regents Of The University Of California | Chimeric antigen receptors and related methods and compositions for the treatment of cancer |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| IL308258A (en) | 2021-05-05 | 2024-01-01 | Immatics Biotechnologies Gmbh | Bma031 antigen binding polypeptides |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| AR130387A1 (es) * | 2022-09-08 | 2024-12-04 | Hoffmann La Roche | Receptores de linfocitos t recombinantes |
| CN116514992B (zh) * | 2022-11-07 | 2024-05-24 | 武汉波睿达生物科技有限公司 | 一种信号肽序列优化的靶向cd19的嵌合抗原受体及其应用 |
| WO2024102954A1 (en) * | 2022-11-10 | 2024-05-16 | Massachusetts Institute Of Technology | Activation induced clipping system (aics) |
| WO2024148337A1 (en) * | 2023-01-05 | 2024-07-11 | Angeles Therapeutics, Inc. | Methods and compositions for gene transduction and to control the activity of synthetic and immune receptors |
| SE548109C2 (en) * | 2023-03-28 | 2026-03-30 | Cerimmune Therapeutics Ab | Microglial endocytic receptors for use in the treatment of neurodegenerative disease |
| KR20250131823A (ko) * | 2023-03-31 | 2025-09-03 | 아벨제타 인크. | Cd20 및 bcma를 표적화하는 이중특이적 키메라 항원 수용체 |
| WO2024229126A2 (en) * | 2023-05-01 | 2024-11-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Mutant interleukin 15 expressing immune cells |
| EP4712986A1 (en) * | 2023-05-18 | 2026-03-25 | A2 Biotherapeutics, Inc. | Immune cells with paired receptors and uses thereof |
| AU2024316791A1 (en) * | 2023-07-28 | 2026-03-12 | Nkilt Therapeutics, Inc. | Chimeric ilt receptor compositions and methods |
| JP2025059072A (ja) * | 2023-09-28 | 2025-04-09 | 沛爾生技醫藥股▲分▼有限公司 | Nkp30膜貫通ドメインを含む単離核酸分子及びこれを含むキメラ抗原受容体 |
| WO2025193475A1 (en) * | 2024-03-14 | 2025-09-18 | The Regents Of The University Of California | Enhancing immune cell innate and adaptive responses |
| WO2025194049A1 (en) * | 2024-03-15 | 2025-09-18 | Dana-Farber Cancer Institute, Inc. | Engineered immune cells and methods of using the same |
| WO2025235862A1 (en) * | 2024-05-10 | 2025-11-13 | Inndura Therapeutics Inc. | A modified immune cell receptor comprising a target-binding domain and the extracellular domain of cd16a |
| US20260015401A1 (en) * | 2024-07-10 | 2026-01-15 | Angeles Therapeutics, Inc. | Compositions and methods comprising epitopes and polypeptides |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1344400A (en) * | 1998-11-18 | 2000-06-05 | Incyte Pharmaceuticals, Inc. | Inflammation-associated genes |
| EP2478760A1 (en) * | 2005-05-10 | 2012-07-25 | Monsanto Technology LLC | Genes and uses for plant improvement |
| WO2013033626A2 (en) * | 2011-08-31 | 2013-03-07 | Trustees Of Dartmouth College | Nkp30 receptor targeted therapeutics |
| BR112014029417B1 (pt) * | 2012-05-25 | 2023-03-07 | Cellectis | Método ex vivo para a preparação de células t para imunoterapia |
| US20150017136A1 (en) * | 2013-07-15 | 2015-01-15 | Cellectis | Methods for engineering allogeneic and highly active t cell for immunotherapy |
| MX367730B (es) * | 2012-09-04 | 2019-09-04 | Cellectis | Receptor de antigeno quimerico multi-cadena y usos del mismo. |
| EP2892930B1 (en) * | 2012-09-07 | 2019-08-14 | University Of Miami | Fusion proteins for promoting an immune response, nucleic acids encoding same, and methods of making and use thereof |
| AU2014266833B2 (en) * | 2013-05-13 | 2020-07-02 | Cellectis | Methods for engineering highly active T cell for immunotherapy |
| FI2997141T3 (fi) * | 2013-05-13 | 2022-12-15 | CD19-spesifinen kimeerinen antigeenireseptori ja sen käyttöjä | |
| BR112017001183A2 (pt) * | 2014-07-21 | 2017-11-28 | Novartis Ag | tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado |
| CN117379460A (zh) * | 2015-03-27 | 2024-01-12 | 免疫生物公司 | 用于治疗癌症的被遗传修饰的nk-92细胞和单克隆抗体 |
| WO2017147269A1 (en) * | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| EP3548055A4 (en) * | 2016-12-02 | 2020-08-19 | University of Southern California | SYNTHETIC IMMUNE RECEPTORS AND THEIR PROCESSES FOR USE |
| CN108728465A (zh) * | 2017-04-14 | 2018-11-02 | 深圳新诺微环生物科技有限公司 | 一种表达靶细胞-效应细胞桥接器的微环dna载体及其制备方法和应用 |
| AU2019231315A1 (en) * | 2018-03-09 | 2020-09-17 | Vivasor, Inc. | Dimeric antigen receptors (DAR) |
| JP7241161B2 (ja) * | 2018-08-01 | 2023-03-16 | イミュニティーバイオ、インコーポレイテッド | 細胞免疫療法の安定した遺伝子改変のための、ホーミング受容体又はサイトカインとキメラ抗原受容体とを含むクアドリシストロニックシステム |
-
2022
- 2022-02-21 KR KR1020237031803A patent/KR20230153529A/ko active Pending
- 2022-02-21 JP JP2023551146A patent/JP2024518011A/ja active Pending
- 2022-02-21 US US18/275,957 patent/US20240390496A1/en active Pending
- 2022-02-21 WO PCT/US2022/017177 patent/WO2022178367A2/en not_active Ceased
- 2022-02-21 IL IL305175A patent/IL305175A/en unknown
- 2022-02-21 AU AU2022224066A patent/AU2022224066A1/en active Pending
- 2022-02-21 EP EP22757078.5A patent/EP4297769A4/en active Pending
- 2022-02-21 CA CA3208717A patent/CA3208717A1/en active Pending
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