JP2023525720A5 - - Google Patents

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Publication number
JP2023525720A5
JP2023525720A5 JP2022567469A JP2022567469A JP2023525720A5 JP 2023525720 A5 JP2023525720 A5 JP 2023525720A5 JP 2022567469 A JP2022567469 A JP 2022567469A JP 2022567469 A JP2022567469 A JP 2022567469A JP 2023525720 A5 JP2023525720 A5 JP 2023525720A5
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JP
Japan
Prior art keywords
cancer
receptor
domain
antigen
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022567469A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023525720A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/031878 external-priority patent/WO2021231505A1/en
Publication of JP2023525720A publication Critical patent/JP2023525720A/ja
Publication of JP2023525720A5 publication Critical patent/JP2023525720A5/ja
Pending legal-status Critical Current

Links

JP2022567469A 2020-05-11 2021-05-11 In vivo形質導入のためのベクター及び方法 Pending JP2023525720A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063023191P 2020-05-11 2020-05-11
US63/023,191 2020-05-11
US202063133224P 2020-12-31 2020-12-31
US63/133,224 2020-12-31
PCT/US2021/031878 WO2021231505A1 (en) 2020-05-11 2021-05-11 Vectors and methods for in vivo transduction

Publications (2)

Publication Number Publication Date
JP2023525720A JP2023525720A (ja) 2023-06-19
JP2023525720A5 true JP2023525720A5 (https=) 2024-05-17

Family

ID=78524914

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567469A Pending JP2023525720A (ja) 2020-05-11 2021-05-11 In vivo形質導入のためのベクター及び方法

Country Status (9)

Country Link
US (1) US20230304031A1 (https=)
EP (1) EP4149495A4 (https=)
JP (1) JP2023525720A (https=)
KR (1) KR20230010231A (https=)
CN (1) CN115968300A (https=)
AU (1) AU2021273253A1 (https=)
CA (1) CA3176697A1 (https=)
IL (1) IL297514A (https=)
WO (1) WO2021231505A1 (https=)

Families Citing this family (8)

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US12351837B2 (en) 2019-01-23 2025-07-08 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
WO2020191233A1 (en) 2019-03-19 2020-09-24 The Broad Institute, Inc. Methods and compositions for editing nucleotide sequences
US12473543B2 (en) 2019-04-17 2025-11-18 The Broad Institute, Inc. Adenine base editors with reduced off-target effects
CN116178567B (zh) * 2022-10-28 2025-01-28 四川大学华西医院 一种靶向TGFβRII的嵌合抗原受体及其用途
EP4724461A1 (en) * 2023-06-07 2026-04-15 The Broad Institute, Inc. Engineered viral like particles (evlps) for the selective transduction of target cells
WO2025033948A1 (ko) * 2023-08-07 2025-02-13 마루테라퓨틱스 주식회사 유전자 고효율 발현이 가능한 비바이러스성 듀얼 플라스미드 벡터와 이를 발현하는 줄기세포 및 분화된 조혈계 세포
CN116814664B (zh) * 2023-08-25 2023-12-12 中国医学科学院肿瘤医院 一种扩展肿瘤识别表位的cea嵌合抗原受体t细胞的制备与应用
CN116814595B (zh) * 2023-08-30 2023-11-28 江苏申基生物科技有限公司 一种腺苷脱氨酶突变体及其固定化

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US5681746A (en) * 1994-12-30 1997-10-28 Chiron Viagene, Inc. Retroviral delivery of full length factor VIII
US7001733B1 (en) * 1998-05-12 2006-02-21 Rigel Pharmaceuticals, Inc. Methods and compositions for screening for modulations of IgE synthesis, secretion and switch rearrangement
US8383124B2 (en) * 2008-03-12 2013-02-26 Children's Hospital Medical Center Mobilization of hematopoietic stem cells
CN102099472A (zh) * 2008-05-19 2011-06-15 新加坡科技研究局 使基因表达靶向于神经胶质瘤的核酸分子和方法
EP2294218A2 (en) * 2008-06-02 2011-03-16 New York University Compositions and methods for diagnosis, prognosis and treatment of mesothelioma
US20110020814A1 (en) * 2009-06-05 2011-01-27 Ipierian, Inc. Methods and compositions for selection of stem cells
JP5923037B2 (ja) * 2009-06-17 2016-05-24 トカジェン インコーポレーテッド 複製可能レトロウイルスベクターの産生細胞
US9839696B2 (en) * 2010-04-30 2017-12-12 City Of Hope Recombinant adeno-associated vectors for targeted treatment
US9642921B2 (en) * 2012-12-20 2017-05-09 Tocagen Inc. Cancer combination therapy and recombinant vectors
CA3051222C (en) * 2013-06-10 2023-01-24 Dana-Farber Cancer Institute, Inc. Methods and compositions for reducing immunosupression by tumor cells
WO2015021077A1 (en) * 2013-08-05 2015-02-12 Tocagen Inc. Recombinant vector with optimized a-bulge
HRP20191873T1 (hr) * 2014-12-12 2020-01-24 Bluebird Bio, Inc. Kimerni antigenski receptori
JP2018526007A (ja) * 2015-09-04 2018-09-13 トカジェン インコーポレーテッド 2aペプチドを含む組換えベクター
US11111505B2 (en) * 2016-03-19 2021-09-07 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
CU24649B1 (es) * 2016-03-19 2023-02-13 Exuma Biotech Corp Retrovirus recombinantes incompetentes de replicación para la transducción de linfocitos y expansión regulada de los mismos
CA3030003A1 (en) * 2016-07-08 2018-01-11 F1 Oncology, Inc. Methods and compositions for transducing lymphocytes and regulating the activity thereof
IL270028B2 (en) * 2017-04-21 2025-10-01 Ospedale San Raffaele Srl Garden care
US20180327857A1 (en) * 2017-05-09 2018-11-15 Shanghai Realgen Biotech Co., Ltd. Diagnostic biomarker and diagnostic method
US20210130775A1 (en) * 2017-08-02 2021-05-06 Autolus Limited Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed
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