JP2021525509A5 - - Google Patents
Info
- Publication number
- JP2021525509A5 JP2021525509A5 JP2020566230A JP2020566230A JP2021525509A5 JP 2021525509 A5 JP2021525509 A5 JP 2021525509A5 JP 2020566230 A JP2020566230 A JP 2020566230A JP 2020566230 A JP2020566230 A JP 2020566230A JP 2021525509 A5 JP2021525509 A5 JP 2021525509A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- antigen
- protein
- cancer
- cell
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024039934A JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862679741P | 2018-06-01 | 2018-06-01 | |
| US62/679,741 | 2018-06-01 | ||
| PCT/US2019/035096 WO2019232503A1 (en) | 2018-06-01 | 2019-06-01 | Diverse antigen binding domains, novel platforms and other enhancements for cellular therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024039934A Division JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021525509A JP2021525509A (ja) | 2021-09-27 |
| JPWO2019232503A5 JPWO2019232503A5 (https=) | 2022-06-07 |
| JP2021525509A5 true JP2021525509A5 (https=) | 2022-06-07 |
| JP7599205B2 JP7599205B2 (ja) | 2024-12-13 |
Family
ID=68697132
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566230A Active JP7599205B2 (ja) | 2018-06-01 | 2019-06-01 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
| JP2024039934A Pending JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024039934A Pending JP2024073564A (ja) | 2018-06-01 | 2024-03-14 | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20210137977A1 (https=) |
| EP (1) | EP3802822A4 (https=) |
| JP (2) | JP7599205B2 (https=) |
| KR (1) | KR20210057705A (https=) |
| CN (1) | CN113286879B (https=) |
| AU (2) | AU2019279084B2 (https=) |
| BR (1) | BR112020024246A2 (https=) |
| CA (1) | CA3101510A1 (https=) |
| CO (1) | CO2020016586A2 (https=) |
| EA (1) | EA202092945A1 (https=) |
| IL (2) | IL279100B2 (https=) |
| MX (1) | MX2020012927A (https=) |
| SG (1) | SG11202011837UA (https=) |
| TW (1) | TW202018083A (https=) |
| WO (1) | WO2019232503A1 (https=) |
| ZA (2) | ZA202007393B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11497768B2 (en) | 2017-06-05 | 2022-11-15 | Mie University | Antigen-binding protein that recognizes MAGE-A4-derived peptide |
| MX2020004185A (es) | 2017-09-27 | 2021-01-08 | Univ Southern California | Nuevas plataformas para coestimulacion, nuevos diseños car y otras mejoras para terapia celular adoptiva. |
| TWI861039B (zh) | 2018-12-21 | 2024-11-11 | 瑞士商赫孚孟拉羅股份公司 | 靶向腫瘤之促效cd28抗原結合分子 |
| EP3733707A1 (en) * | 2019-04-30 | 2020-11-04 | Celyad S.A. | Car t-cells targeting bcma and uses thereof |
| EP4041256A4 (en) * | 2019-10-10 | 2023-11-08 | Arizona Board of Regents on behalf of Arizona State University | Oncolytic viruses that express multi-specific immune cell engagers |
| EP3842461A1 (en) * | 2019-12-23 | 2021-06-30 | Albert-Ludwigs-Universität Freiburg | Chimeric antigen receptors that bind to prostate specific membrane antigen |
| US20230060351A1 (en) * | 2020-01-08 | 2023-03-02 | Board Of Regents, The University Of Texas System | A method of engineering natural killer cells to target cd70-positive tumors |
| JP2023518049A (ja) | 2020-03-16 | 2023-04-27 | ユニバーシティ オブ サザン カリフォルニア | 新規な抗原結合ドメインおよびそれを組み込んだ合成抗原受容体 |
| KR20230009386A (ko) * | 2020-04-10 | 2023-01-17 | 주노 쎄러퓨티크스 인코퍼레이티드 | B-세포 성숙 항원을 표적화하는 키메라 항원 수용체로 조작된 세포 요법 관련 방법 및 용도 |
| IL297553A (en) * | 2020-04-24 | 2022-12-01 | Memorial Sloan Kettering Cancer Center | Chimeric antigen receptors targeting cd19 and their use |
| TW202208412A (zh) * | 2020-05-06 | 2022-03-01 | 瑞士商Crispr治療公司 | 對酪胺酸蛋白激酶樣7(ptk7)特異的經掩蔽的嵌合抗原受體和表現其的免疫細胞 |
| WO2021231237A2 (en) * | 2020-05-11 | 2021-11-18 | Augmenta Bioworks, Inc. | Antibodies for sars-cov-2 and uses thereof |
| EP4168046A4 (en) * | 2020-06-18 | 2024-10-16 | Nextcure, Inc. | COMPOSITIONS AND METHODS FOR MODULATING FLRT3-MEDIATED SIGNAL TRANSDUCTION |
| CN116490208A (zh) * | 2020-08-06 | 2023-07-25 | 史坦利科西斯治疗有限责任公司 | Il-8抗体及其使用方法 |
| WO2022068141A1 (zh) * | 2020-09-29 | 2022-04-07 | 昆明赛诺制药股份有限公司 | 人源化抗-cd22重组免疫毒素及其应用 |
| CA3201008A1 (en) * | 2020-12-02 | 2022-06-09 | Shanghai Cellular Biopharmaceutical Group Ltd. | Bcma-targeted chimeric antigen receptors |
| WO2022170126A2 (en) * | 2021-02-05 | 2022-08-11 | Adagio Therapeutics, Inc. | Compounds specific to coronavirus s protein and uses thereof |
| AU2022227021A1 (en) * | 2021-02-26 | 2023-09-21 | Kelonia Therapeutics, Inc. | Lymphocyte targeted lentiviral vectors |
| CN115491358B (zh) * | 2021-06-17 | 2024-09-06 | 复星凯特生物科技有限公司 | 一种靶向b7-h3和folr1双打靶点car t的制备及应用 |
| TW202330595A (zh) * | 2021-09-29 | 2023-08-01 | 美商莫德斯醫療公司 | 抗原結合多肽、抗原結合多肽複合物及其使用方法 |
| JP2024540099A (ja) | 2021-10-28 | 2024-10-31 | ライエル・イミュノファーマ・インコーポレイテッド | Ror1結合タンパク質を発現する細胞を培養する方法 |
| CN114106199B (zh) * | 2021-11-19 | 2022-07-12 | 广州百暨基因科技有限公司 | 靶向adgre2的嵌合抗原受体及其应用 |
| WO2023147784A1 (zh) * | 2022-02-07 | 2023-08-10 | 江苏恒瑞医药股份有限公司 | 特异性结合psma和cd3的抗原结合分子及其医药用途 |
| WO2023170549A1 (en) * | 2022-03-07 | 2023-09-14 | Medimmune Llc | Treatment methods using ctla-4 and pd-1 bispecific antibodies |
| WO2023175069A1 (en) * | 2022-03-16 | 2023-09-21 | Medigene Immunotherapies Gmbh | Tcr constant region pairing library for pramevld tcrs |
| EP4493583A1 (en) * | 2022-03-16 | 2025-01-22 | Medigene Immunotherapies GmbH | Tcr constant region pairing library |
| GB202208119D0 (en) * | 2022-06-01 | 2022-07-13 | Univ Oslo Hf | Anti-steap1 car |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024136899A1 (en) * | 2022-12-21 | 2024-06-27 | Synthorx, Inc. | Cancer therapy with il-2 conjugates and chimeric antigen receptor therapies |
| GB202301421D0 (en) * | 2023-02-01 | 2023-03-15 | Univ Oslo Hf | Switch receptor for use in adoptive cell therapy |
| CA3278900A1 (en) | 2023-03-31 | 2024-10-03 | AbelZeta Inc. | BISPECIFIC CHIMERIC ANTIGENIC RECEPTORS TARGETING CD20 AND BCMA |
| WO2024220834A1 (en) * | 2023-04-19 | 2024-10-24 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Car-t cells co-expressing cd40l |
| WO2024243093A2 (en) * | 2023-05-19 | 2024-11-28 | The Regents Of The University Of California | Multispecific antibodies targeting cd3 and cd22 |
| AU2024353243A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Antigen binding polypeptides |
| AU2024353718A1 (en) | 2023-09-25 | 2026-04-09 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| WO2025151607A1 (en) * | 2024-01-10 | 2025-07-17 | Santa Ana Bio, Inc. | Methods and compositions for treating autoimmune, allergic and inflammatory diseases |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
| WO2025245381A1 (en) | 2024-05-23 | 2025-11-27 | The Trustrees Of Dartmouth College | Methods and compositions for enhancing the persistence of car expressing tregs in the cns and other tissues |
| WO2025257781A1 (en) * | 2024-06-14 | 2025-12-18 | Novartis Ag | Treatment of systemic sclerosis using anti-baff-r antibodies |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| EP1958962A3 (en) | 1997-06-12 | 2013-05-01 | Novartis International Pharmaceutical Ltd. | Artificial antibody polypeptides |
| GB9809658D0 (en) * | 1998-05-06 | 1998-07-01 | Celltech Therapeutics Ltd | Biological products |
| CN1294148C (zh) | 2001-04-11 | 2007-01-10 | 中国科学院遗传与发育生物学研究所 | 环状单链三特异抗体 |
| KR20060041205A (ko) | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| JP2008512352A (ja) | 2004-07-17 | 2008-04-24 | イムクローン システムズ インコーポレイティド | 新規な四価の二重特異性抗体 |
| WO2010085660A2 (en) * | 2009-01-23 | 2010-07-29 | Roger Williams Hospital | Viral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| EP2694549B1 (en) | 2011-04-08 | 2018-08-15 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Anti-epidermal growth factor receptor variant iii chimeric antigen receptors and use of same for the treatment of cancer |
| US9833476B2 (en) * | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| CN107058101B (zh) | 2011-10-17 | 2021-06-01 | 麻省理工学院 | 细胞内传递 |
| EP2970312B1 (en) | 2013-03-11 | 2017-11-15 | The Regents of The University of Michigan | Bet bromodomain inhibitors and therapeutic methods using the same |
| WO2014160030A2 (en) | 2013-03-13 | 2014-10-02 | Health Research, Inc. | Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen |
| CN106459990B (zh) | 2014-02-07 | 2021-06-01 | 麦克马斯特大学 | 三功能t细胞抗原偶联物及其制备方法和用途 |
| WO2015158671A1 (en) * | 2014-04-14 | 2015-10-22 | Cellectis | Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy |
| TWI750110B (zh) * | 2014-07-21 | 2021-12-21 | 瑞士商諾華公司 | 使用人類化抗-bcma嵌合抗原受體治療癌症 |
| WO2016174852A1 (ja) * | 2015-04-30 | 2016-11-03 | 株式会社デンソー | 蒸発器 |
| CN107995913B (zh) | 2015-05-18 | 2022-02-11 | T细胞受体治疗公司 | 使用融合蛋白对tcr重编程的组合物和方法 |
| TWI833684B (zh) * | 2015-06-25 | 2024-03-01 | 美商生物細胞基因治療有限公司 | 嵌合抗原受體(car)、組合物及其使用方法 |
| EP3842450A1 (en) * | 2015-10-23 | 2021-06-30 | Eureka Therapeutics, Inc. | Antibody/t-cell receptor chimeric constructs and uses thereof |
| WO2017172981A2 (en) * | 2016-03-29 | 2017-10-05 | University Of Southern California | Chimeric antigen receptors targeting cancer |
| CA3018253A1 (en) | 2016-03-31 | 2017-10-05 | University Of Southern California | A highly sensitive and specific luciferase based reporter assay for antigen detection |
| EP3479003B1 (en) | 2016-06-30 | 2023-11-01 | Illinois Tool Works Inc. | Device for holding an electronic gadget |
| CN110352068A (zh) * | 2016-12-02 | 2019-10-18 | 南加利福尼亚大学 | 合成的免疫受体及其使用方法 |
| MX2020004185A (es) | 2017-09-27 | 2021-01-08 | Univ Southern California | Nuevas plataformas para coestimulacion, nuevos diseños car y otras mejoras para terapia celular adoptiva. |
| AU2022224066A1 (en) * | 2021-02-19 | 2023-09-07 | Angeles Therapeutics, Inc. | Single-chain and multi-chain synthetic antigen receptors for diverse immune cells |
-
2019
- 2019-06-01 MX MX2020012927A patent/MX2020012927A/es unknown
- 2019-06-01 EA EA202092945A patent/EA202092945A1/ru unknown
- 2019-06-01 SG SG11202011837UA patent/SG11202011837UA/en unknown
- 2019-06-01 BR BR112020024246-2A patent/BR112020024246A2/pt unknown
- 2019-06-01 KR KR1020207038038A patent/KR20210057705A/ko active Pending
- 2019-06-01 IL IL279100A patent/IL279100B2/en unknown
- 2019-06-01 WO PCT/US2019/035096 patent/WO2019232503A1/en not_active Ceased
- 2019-06-01 IL IL317990A patent/IL317990A/en unknown
- 2019-06-01 US US15/734,203 patent/US20210137977A1/en active Pending
- 2019-06-01 EP EP19811044.7A patent/EP3802822A4/en active Pending
- 2019-06-01 CA CA3101510A patent/CA3101510A1/en active Pending
- 2019-06-01 AU AU2019279084A patent/AU2019279084B2/en active Active
- 2019-06-01 JP JP2020566230A patent/JP7599205B2/ja active Active
- 2019-06-01 CN CN201980049331.5A patent/CN113286879B/zh active Active
- 2019-06-03 TW TW108119201A patent/TW202018083A/zh unknown
-
2020
- 2020-11-26 ZA ZA2020/07393A patent/ZA202007393B/en unknown
- 2020-12-29 CO CONC2020/0016586A patent/CO2020016586A2/es unknown
-
2022
- 2022-05-23 ZA ZA2022/05644A patent/ZA202205644B/en unknown
-
2024
- 2024-03-14 JP JP2024039934A patent/JP2024073564A/ja active Pending
-
2025
- 2025-07-16 AU AU2025205493A patent/AU2025205493A1/en active Pending
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