JP2022541441A5 - - Google Patents
Info
- Publication number
- JP2022541441A5 JP2022541441A5 JP2022502275A JP2022502275A JP2022541441A5 JP 2022541441 A5 JP2022541441 A5 JP 2022541441A5 JP 2022502275 A JP2022502275 A JP 2022502275A JP 2022502275 A JP2022502275 A JP 2022502275A JP 2022541441 A5 JP2022541441 A5 JP 2022541441A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- derived
- cell
- car
- mica
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025109951A JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875490P | 2019-07-17 | 2019-07-17 | |
| US62/875,490 | 2019-07-17 | ||
| US202063021560P | 2020-05-07 | 2020-05-07 | |
| US63/021,560 | 2020-05-07 | ||
| PCT/US2020/042657 WO2021011919A1 (en) | 2019-07-17 | 2020-07-17 | Immune effector cell engineering and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025109951A Division JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022541441A JP2022541441A (ja) | 2022-09-26 |
| JP2022541441A5 true JP2022541441A5 (https=) | 2023-07-21 |
Family
ID=74211221
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502275A Pending JP2022541441A (ja) | 2019-07-17 | 2020-07-17 | 免疫エフェクター細胞操作およびその使用 |
| JP2025109951A Pending JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025109951A Pending JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20220275333A1 (https=) |
| EP (1) | EP3999628A4 (https=) |
| JP (2) | JP2022541441A (https=) |
| KR (1) | KR20220035190A (https=) |
| CN (1) | CN114258429A (https=) |
| AU (1) | AU2020314969A1 (https=) |
| BR (1) | BR112022000641A2 (https=) |
| CA (1) | CA3146967A1 (https=) |
| IL (1) | IL289830A (https=) |
| MX (1) | MX2022000553A (https=) |
| WO (1) | WO2021011919A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| US20230248768A1 (en) * | 2020-07-15 | 2023-08-10 | Nanjing Bioheng Biotech Co., Ltd | Engineered immune cell for allotransplantation |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CA3204417A1 (en) * | 2021-01-29 | 2022-08-04 | Allogene Therapeutics, Inc. | Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products |
| CN116897202A (zh) * | 2021-02-24 | 2023-10-17 | 科济生物医药(上海)有限公司 | Tigit工程化细胞及其组合物 |
| WO2022179620A1 (zh) * | 2021-02-25 | 2022-09-01 | 克莱格医学有限公司 | Cd94工程化细胞及其组合物 |
| AU2022228364A1 (en) * | 2021-03-05 | 2023-09-14 | Factor Bioscience Inc. | Engineered immune cell therapies |
| JP2024514522A (ja) * | 2021-04-07 | 2024-04-02 | センチュリー セラピューティクス,インコーポレイテッド | 遺伝子導入ベクターおよび細胞を操作する方法 |
| KR20240011831A (ko) * | 2021-05-26 | 2024-01-26 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법 |
| US20240316102A1 (en) | 2021-07-01 | 2024-09-26 | Indapta Therapeutics, Inc. | Engineered natural killer (nk) cells and related methods |
| AU2022304599A1 (en) * | 2021-07-02 | 2024-01-18 | Fate Therapeutics, Inc. | Protected effector cells and use thereof for allogeneic adoptive cell therapies |
| CN117835993A (zh) * | 2021-08-18 | 2024-04-05 | 菲特治疗公司 | 作为单一疗法以及与抗体组合的现成的iPSC衍生的CAR-NK细胞 |
| IL312565A (en) * | 2021-11-08 | 2024-07-01 | Fate Therapeutics Inc | Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors |
| KR20240102994A (ko) * | 2021-11-08 | 2024-07-03 | 페이트 세러퓨틱스, 인코포레이티드 | 고형 종양의 유비쿼터스 표적화를 향상시키는 조작된 이펙터 세포 및 방법 |
| US20250228943A1 (en) * | 2022-04-08 | 2025-07-17 | Fate Therapeutics, Inc. | Cells having solid tumor targeting backbone and use thereof |
| US20250222029A1 (en) | 2022-04-08 | 2025-07-10 | Fate Therapeutics, Inc. | Chimeric antigen receptor for tumor targeting |
| US20260108554A1 (en) * | 2022-05-01 | 2026-04-23 | Factor Bioscience Inc. | Methods for reprogramming and gene editing cells |
| JP2025525439A (ja) | 2022-06-30 | 2025-08-05 | インダプタ セラピューティクス インコーポレイテッド | 操作されたナチュラルキラー(nk)細胞と抗体療法との組み合わせおよび関連する方法 |
| US20260071238A1 (en) * | 2022-09-02 | 2026-03-12 | Janssen Biotech, Inc. | Materials and processes for engineering hypoimmunogenicity |
| WO2024068617A1 (en) * | 2022-09-26 | 2024-04-04 | Institut Curie | Myeloid cells expressing il-2 and uses thereof for quick anticancer therapy |
| AU2023353199A1 (en) * | 2022-09-27 | 2025-03-20 | Genentech, Inc. | Inhibition of genotoxic stress to improve t cell engineering |
| GB202218144D0 (en) * | 2022-12-02 | 2023-01-18 | Univ Oxford Innovation Ltd | Product |
| CN120826463A (zh) * | 2023-03-31 | 2025-10-21 | 杭州启函生物科技有限公司 | 使用工程化细胞的癌症免疫疗法 |
| WO2025101471A1 (en) * | 2023-11-09 | 2025-05-15 | Merck Sharp & Dohme Llc | Anti-cd27 antibody cell-based biological potency assay |
| CN118703438B (zh) * | 2024-08-30 | 2025-01-14 | 星奕昂(上海)生物科技有限公司 | 一种活化和扩增自然杀伤细胞的方法及其用途 |
| CN119220607B (zh) * | 2024-12-03 | 2025-03-07 | 星奕昂(上海)生物科技有限公司 | 编辑tim3基因获得功能强化的car-nk细胞的方法与应用 |
| CN119552808A (zh) * | 2025-01-24 | 2025-03-04 | 上海元戊医学技术有限公司 | 通用型诱导多能干细胞及其制备方法与应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| JP2005500061A (ja) | 2001-08-20 | 2005-01-06 | ザ スクリップス リサーチ インスティテュート | Cnnについての亜鉛フィンガー結合ドメイン |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| WO2005118788A2 (en) | 2004-05-27 | 2005-12-15 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| WO2007142241A1 (ja) * | 2006-06-05 | 2007-12-13 | Hiroshima University | 抗cd38抗体を細胞表面に有する免疫担当細胞 |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| WO2011159726A2 (en) | 2010-06-14 | 2011-12-22 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| MX2014001222A (es) | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
| CA2861491C (en) | 2012-02-13 | 2020-08-25 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| BR112014029417B1 (pt) | 2012-05-25 | 2023-03-07 | Cellectis | Método ex vivo para a preparação de células t para imunoterapia |
| US9932607B2 (en) | 2013-11-15 | 2018-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Site-specific integration of transgenes into human cells |
| US10934346B2 (en) | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| PT3122769T (pt) | 2014-03-28 | 2023-04-24 | Univ Minnesota | Polipéptidos, células e métodos que envolvem cd16 manipulado |
| AU2015312117A1 (en) | 2014-09-02 | 2017-03-02 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides |
| WO2016154585A1 (en) * | 2015-03-26 | 2016-09-29 | Charles Sentman | Anti-mica antigen binding fragments, fusion molecules, cells which express and methods of using |
| US9790490B2 (en) * | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| KR20250141836A (ko) * | 2015-11-04 | 2025-09-29 | 페이트 세러퓨틱스, 인코포레이티드 | 만능 세포의 유전자 조작 |
| US20170166877A1 (en) | 2015-12-14 | 2017-06-15 | Bellicum Pharmaceuticals, Inc. | Dual controls for therapeutic cell activation or elimination |
| US11421032B2 (en) * | 2017-05-22 | 2022-08-23 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for inhibition of MICA/B shedding |
| MX2020004568A (es) * | 2017-11-06 | 2020-10-05 | Juno Therapeutics Inc | Combinación de una terapia celular y un inhibidor de gamma secretasa. |
| JP7807196B2 (ja) * | 2017-12-05 | 2026-01-27 | セリアド オンコロジー エス.アー. | Nkg2dベースの受容体を発現する免疫細胞のフラトリサイドの減少 |
| JP2021505131A (ja) * | 2017-12-08 | 2021-02-18 | フェイト セラピューティクス,インコーポレイテッド | 増強されたiPSC由来のエフェクター細胞を用いた免疫療法 |
| IL316257A (en) * | 2017-12-22 | 2024-12-01 | Fate Therapeutics Inc | Enhanced immune effector cells and use thereof |
-
2020
- 2020-07-17 CN CN202080058417.7A patent/CN114258429A/zh active Pending
- 2020-07-17 JP JP2022502275A patent/JP2022541441A/ja active Pending
- 2020-07-17 AU AU2020314969A patent/AU2020314969A1/en active Pending
- 2020-07-17 KR KR1020227005062A patent/KR20220035190A/ko active Pending
- 2020-07-17 BR BR112022000641A patent/BR112022000641A2/pt unknown
- 2020-07-17 MX MX2022000553A patent/MX2022000553A/es unknown
- 2020-07-17 US US17/627,574 patent/US20220275333A1/en active Pending
- 2020-07-17 WO PCT/US2020/042657 patent/WO2021011919A1/en not_active Ceased
- 2020-07-17 EP EP20839948.5A patent/EP3999628A4/en active Pending
- 2020-07-17 CA CA3146967A patent/CA3146967A1/en active Pending
-
2021
- 2021-01-29 US US17/163,040 patent/US20210163622A1/en not_active Abandoned
-
2022
- 2022-01-13 IL IL289830A patent/IL289830A/en unknown
-
2025
- 2025-06-30 JP JP2025109951A patent/JP2025157281A/ja active Pending
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