JP2022510207A5 - - Google Patents

Info

Publication number
JP2022510207A5
JP2022510207A5 JP2021530163A JP2021530163A JP2022510207A5 JP 2022510207 A5 JP2022510207 A5 JP 2022510207A5 JP 2021530163 A JP2021530163 A JP 2021530163A JP 2021530163 A JP2021530163 A JP 2021530163A JP 2022510207 A5 JP2022510207 A5 JP 2022510207A5
Authority
JP
Japan
Prior art keywords
cells
derived
cell
antigen
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021530163A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022510207A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/063024 external-priority patent/WO2020117526A1/en
Publication of JP2022510207A publication Critical patent/JP2022510207A/ja
Publication of JP2022510207A5 publication Critical patent/JP2022510207A5/ja
Priority to JP2025018442A priority Critical patent/JP2025072543A/ja
Pending legal-status Critical Current

Links

JP2021530163A 2018-12-02 2019-11-25 増強されたiPSC派生エフェクター細胞を使用した免疫療法 Pending JP2022510207A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025018442A JP2025072543A (ja) 2018-12-02 2025-02-06 増強されたiPSC派生エフェクター細胞を使用した免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862774278P 2018-12-02 2018-12-02
US62/774,278 2018-12-02
PCT/US2019/063024 WO2020117526A1 (en) 2018-12-02 2019-11-25 IMMUNOTHERAPIES USING ENHANCED iPSC DERIVED EFFECTOR CELLS

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025018442A Division JP2025072543A (ja) 2018-12-02 2025-02-06 増強されたiPSC派生エフェクター細胞を使用した免疫療法

Publications (2)

Publication Number Publication Date
JP2022510207A JP2022510207A (ja) 2022-01-26
JP2022510207A5 true JP2022510207A5 (https=) 2022-12-12

Family

ID=70974390

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021530163A Pending JP2022510207A (ja) 2018-12-02 2019-11-25 増強されたiPSC派生エフェクター細胞を使用した免疫療法
JP2025018442A Pending JP2025072543A (ja) 2018-12-02 2025-02-06 増強されたiPSC派生エフェクター細胞を使用した免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025018442A Pending JP2025072543A (ja) 2018-12-02 2025-02-06 増強されたiPSC派生エフェクター細胞を使用した免疫療法

Country Status (12)

Country Link
US (1) US12435123B2 (https=)
EP (1) EP3891177A4 (https=)
JP (2) JP2022510207A (https=)
KR (1) KR102943217B1 (https=)
CN (1) CN113166232A (https=)
AU (1) AU2019392265A1 (https=)
BR (1) BR112021010331A2 (https=)
CA (1) CA3121128A1 (https=)
IL (1) IL283607A (https=)
MX (1) MX2021006194A (https=)
SG (1) SG11202105480WA (https=)
WO (1) WO2020117526A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022025806A2 (pt) * 2020-06-19 2023-03-07 Fate Therapeutics Inc Combinação de tipos de células efetoras derivadas de ipsc para uso em imunoterapia
CN114525255A (zh) * 2020-10-30 2022-05-24 未来智人再生医学研究院(广州)有限公司 一种表达il-11的多能干细胞衍生物及其应用
EP4240832A4 (en) * 2020-11-04 2025-01-01 Fate Therapeutics, Inc. Engineered ipsc and immune effector cells for heterogenous tumor control
AU2021372975A1 (en) * 2020-11-04 2023-06-15 Fate Therapeutics, Inc. Engineered ipsc and persistent immune effector cells
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
KR20230118887A (ko) 2020-12-03 2023-08-14 센츄리 쎄라퓨틱스 인코포레이티드 유전자 조작 세포 및 이의 용도
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
CA3204417A1 (en) * 2021-01-29 2022-08-04 Allogene Therapeutics, Inc. Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products
WO2022179620A1 (zh) * 2021-02-25 2022-09-01 克莱格医学有限公司 Cd94工程化细胞及其组合物
WO2022216624A1 (en) * 2021-04-07 2022-10-13 Century Therapeutics, Inc. Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells
JP2024522756A (ja) * 2021-06-18 2024-06-21 オーエヌケイ セラピューティクス リミテッド ダブルノックアウトナチュラルキラー細胞
CN118284686A (zh) * 2021-11-24 2024-07-02 杭州启函生物科技有限公司 用于基于细胞的免疫疗法的系统和方法
EP4353741A1 (en) * 2022-10-14 2024-04-17 ONK Therapeutics Limited Double knockout natural killer cells
WO2024183750A1 (en) * 2023-03-07 2024-09-12 Qihan Hong Kong Limited A novel immune cell and use thereof for treating diseases
WO2025189046A2 (en) * 2024-03-06 2025-09-12 The Johns Hopkins University Pantigen specific cytokine receptor stimulation of immune cell function

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
GB9710807D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
GB9725764D0 (en) 1997-12-04 1998-02-04 Isis Innovation HLA-E binding
US6140081A (en) 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6453242B1 (en) 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
JP2002060786A (ja) 2000-08-23 2002-02-26 Kao Corp 硬質表面用殺菌防汚剤
JP2005500061A (ja) 2001-08-20 2005-01-06 ザ スクリップス リサーチ インスティテュート Cnnについての亜鉛フィンガー結合ドメイン
US7745140B2 (en) 2002-01-03 2010-06-29 The Trustees Of The University Of Pennsylvania Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US7972854B2 (en) 2004-02-05 2011-07-05 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
WO2005118788A2 (en) 2004-05-27 2005-12-15 The Trustees Of The University Of Pennsylvania Novel artificial antigen presenting cells and uses therefor
NZ573646A (en) 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
EP2035452B1 (en) * 2006-06-22 2012-04-25 Novo Nordisk A/S Soluble heterodimeric receptors and uses thereof
WO2011072246A2 (en) 2009-12-10 2011-06-16 Regents Of The University Of Minnesota Tal effector-mediated dna modification
WO2011159726A2 (en) 2010-06-14 2011-12-22 The Scripps Research Institute Reprogramming of cells to a new fate
MX2014001222A (es) 2011-07-29 2014-09-15 Univ Pennsylvania Receptores coestimuladores de cambio.
CA2861491C (en) 2012-02-13 2020-08-25 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
BR112014029417B1 (pt) 2012-05-25 2023-03-07 Cellectis Método ex vivo para a preparação de células t para imunoterapia
DK2956175T3 (da) 2013-02-15 2017-11-27 Univ California Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
US9932607B2 (en) 2013-11-15 2018-04-03 The Board Of Trustees Of The Leland Stanford Junior University Site-specific integration of transgenes into human cells
US10934346B2 (en) 2014-02-14 2021-03-02 Bellicum Pharmaceuticals, Inc. Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
KR102375998B1 (ko) 2014-02-14 2022-03-21 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 키메라 항원 수용체 및 제조방법
CA2941004A1 (en) 2014-03-04 2015-09-11 Peter Flynn Improved reprogramming methods and cell culture platforms
PT3122769T (pt) 2014-03-28 2023-04-24 Univ Minnesota Polipéptidos, células e métodos que envolvem cd16 manipulado
AU2015312117A1 (en) 2014-09-02 2017-03-02 Bellicum Pharmaceuticals, Inc. Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides
CN117737124A (zh) 2015-10-16 2024-03-22 菲特治疗公司 用于诱导和维护基态多能性的平台
SG11201803145RA (en) 2015-11-04 2018-05-30 Fate Therapeutics Inc Methods and compositions for inducing hematopoietic cell differentiation
US20170166877A1 (en) 2015-12-14 2017-06-15 Bellicum Pharmaceuticals, Inc. Dual controls for therapeutic cell activation or elimination
SG11201805186VA (en) * 2016-01-20 2018-07-30 Fate Therapeutics Inc Compositions and methods for immune cell modulation in adoptive immunotherapies
IL316257A (en) 2017-12-22 2024-12-01 Fate Therapeutics Inc Enhanced immune effector cells and use thereof

Similar Documents

Publication Publication Date Title
JP2022510207A5 (https=)
JP2021505131A5 (https=)
JP2022548943A5 (https=)
JP2022541441A5 (https=)
JP2022550899A5 (https=)
US20260055157A1 (en) Methods of making chimeric antigen receptor-expressing cells
CN112029001B (zh) 靶向nk激活性受体的嵌合抗原受体
JP2023505206A5 (https=)
JP2023530704A5 (https=)
JP2021519061A5 (https=)
JP2023548467A5 (https=)
AU2015374296B2 (en) Methods of making chimeric antigen receptor-expressing cells
JP2023549098A5 (https=)
CN114761425A (zh) 用于免疫效应细胞工程化的增强的嵌合抗原受体和其用途
JP2023548829A5 (https=)
EP4506036A2 (en) Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof
JP2023545992A5 (https=)
CN111787938A (zh) 靶向bcma的嵌合抗原受体、靶向cd19的嵌合抗原受体及组合疗法
CN114901693A (zh) 用于免疫效应细胞工程化的增强的嵌合抗原受体和其用途
JP2022510207A (ja) 増強されたiPSC派生エフェクター細胞を使用した免疫療法
RS62870B1 (sr) Himerni antigenski receptori sa ciljanim delovanjem na receptore spregnute sa g-proteinom i njihove upotrebe
CA3032054A1 (en) Combination therapies of chimeric antigen receptors and pd-1 inhibitors
JP2023029624A (ja) strepタグ特異的キメラ受容体およびその使用
JP2024502157A (ja) 樹状細胞活性化キメラ抗原受容体及びその使用
KR102883294B1 (ko) 조작된 iPSC 및 보강된 면역 효과기 세포