KR20220035190A - 면역 효과기 세포 조작 및 이의 용도 - Google Patents

면역 효과기 세포 조작 및 이의 용도 Download PDF

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KR20220035190A
KR20220035190A KR1020227005062A KR20227005062A KR20220035190A KR 20220035190 A KR20220035190 A KR 20220035190A KR 1020227005062 A KR1020227005062 A KR 1020227005062A KR 20227005062 A KR20227005062 A KR 20227005062A KR 20220035190 A KR20220035190 A KR 20220035190A
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cell
cells
car
mica
differentiated
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바흐람 발라메르
톰 통 리
라이언 비요르달
조드 굿리지
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페이트 세러퓨틱스, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C07K16/2833—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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KR1020227005062A 2019-07-17 2020-07-17 면역 효과기 세포 조작 및 이의 용도 Pending KR20220035190A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962875490P 2019-07-17 2019-07-17
US62/875,490 2019-07-17
US202063021560P 2020-05-07 2020-05-07
US63/021,560 2020-05-07
PCT/US2020/042657 WO2021011919A1 (en) 2019-07-17 2020-07-17 Immune effector cell engineering and use thereof

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KR20220035190A true KR20220035190A (ko) 2022-03-21

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US (2) US20220275333A1 (https=)
EP (1) EP3999628A4 (https=)
JP (2) JP2022541441A (https=)
KR (1) KR20220035190A (https=)
CN (1) CN114258429A (https=)
AU (1) AU2020314969A1 (https=)
BR (1) BR112022000641A2 (https=)
CA (1) CA3146967A1 (https=)
IL (1) IL289830A (https=)
MX (1) MX2022000553A (https=)
WO (1) WO2021011919A1 (https=)

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US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
US20230248768A1 (en) * 2020-07-15 2023-08-10 Nanjing Bioheng Biotech Co., Ltd Engineered immune cell for allotransplantation
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
CA3204417A1 (en) * 2021-01-29 2022-08-04 Allogene Therapeutics, Inc. Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products
CN116897202A (zh) * 2021-02-24 2023-10-17 科济生物医药（上海）有限公司 Tigit工程化细胞及其组合物
WO2022179620A1 (zh) * 2021-02-25 2022-09-01 克莱格医学有限公司 Cd94工程化细胞及其组合物
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