CN111954715A - 工程改造的免疫效应细胞和其用途 - Google Patents

工程改造的免疫效应细胞和其用途 Download PDF

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CN111954715A
CN111954715A CN201980021676.XA CN201980021676A CN111954715A CN 111954715 A CN111954715 A CN 111954715A CN 201980021676 A CN201980021676 A CN 201980021676A CN 111954715 A CN111954715 A CN 111954715A
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cells
cell
derived
receptor
car
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Chinese (zh)
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B·瓦拉梅尔
R·比乔戴尔
J·古德里奇
T·T·李
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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Priority claimed from PCT/US2018/067289 external-priority patent/WO2019126748A1/en
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CN201980021676.XA 2018-03-29 2019-03-28 工程改造的免疫效应细胞和其用途 Pending CN111954715A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862649781P 2018-03-29 2018-03-29
US62/649,781 2018-03-29
US201862774052P 2018-11-30 2018-11-30
US62/774,052 2018-11-30
PCT/US2018/067289 WO2019126748A1 (en) 2017-12-22 2018-12-21 Enhanced immune effector cells and use thereof
USPCT/US2018/067289 2018-12-21
PCT/US2019/024686 WO2019191495A1 (en) 2018-03-29 2019-03-28 Engineered immune effector cells and use thereof

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CN111954715A true CN111954715A (zh) 2020-11-17

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US (1) US20210024959A1 (https=)
EP (1) EP3775228B1 (https=)
JP (2) JP7575271B2 (https=)
KR (2) KR102817092B1 (https=)
CN (1) CN111954715A (https=)
AU (2) AU2019243315A1 (https=)
BR (1) BR112020019205A2 (https=)
CA (1) CA3093020A1 (https=)
IL (1) IL277611A (https=)
MX (1) MX2020009896A (https=)
SG (1) SG11202008977UA (https=)
WO (1) WO2019191495A1 (https=)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110628821A (zh) * 2018-06-25 2019-12-31 首都医科大学宣武医院 一种细胞模型及其制备方法、应用
CN113278652A (zh) * 2021-07-20 2021-08-20 卡瑞济(北京)生命科技有限公司 增加Survivin表达的CAR-T细胞并联合IL-15在制备抗肿瘤药物中的应用
CN114107211A (zh) * 2020-12-04 2022-03-01 未来智人再生医学研究院(广州)有限公司 一种多能干细胞及其衍生物
CN114645018A (zh) * 2020-12-18 2022-06-21 未来智人再生医学研究院(广州)有限公司 一种表达cd38靶向抑制因子的多能干细胞及其衍生物与应用
CN114657133A (zh) * 2020-12-22 2022-06-24 未来智人再生医学研究院(广州)有限公司 一种表达靶向IL-4 Rα的shRNA和/或shRNA-miR的多能干细胞
CN114657137A (zh) * 2020-12-22 2022-06-24 未来智人再生医学研究院(广州)有限公司 一种表达靶向BTLA的shRNA和/或shRNA-miR的多能干细胞或其衍生物
CN114774469A (zh) * 2022-06-22 2022-07-22 南京艾尔普再生医学科技有限公司 一种adcc功能增强的nk细胞的制作方法、nk细胞及其组合物
WO2023083003A1 (zh) * 2021-11-11 2023-05-19 北恒医疗有限公司 工程化免疫细胞及其用途
WO2023116929A1 (en) * 2021-12-24 2023-06-29 Hemacell Therapeutics Inc. Method for producing human induced pluripotent stem cells through homologous recombination and integrase-mediated recombination
WO2023179772A1 (zh) * 2022-03-25 2023-09-28 士泽生物医药（苏州）有限公司 一种通用型细胞及其制备方法
CN119264271A (zh) * 2024-10-08 2025-01-07 北京市神经外科研究所 一种nk细胞特异性的嵌合抗原受体及其应用
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