AU2019243315A1 - Engineered immune effector cells and use thereof - Google Patents

Engineered immune effector cells and use thereof Download PDF

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Publication number
AU2019243315A1
AU2019243315A1 AU2019243315A AU2019243315A AU2019243315A1 AU 2019243315 A1 AU2019243315 A1 AU 2019243315A1 AU 2019243315 A AU2019243315 A AU 2019243315A AU 2019243315 A AU2019243315 A AU 2019243315A AU 2019243315 A1 AU2019243315 A1 AU 2019243315A1
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Australia
Prior art keywords
cell
cells
ipsc
receptor
derivative
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Abandoned
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AU2019243315A
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English (en)
Inventor
Ryan BJORDAHL
Jode GOODRIDGE
Tom Tong LEE
Bahram Valamehr
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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Publication date
Priority claimed from PCT/US2018/067289 external-priority patent/WO2019126748A1/en
Application filed by Fate Therapeutics Inc filed Critical Fate Therapeutics Inc
Publication of AU2019243315A1 publication Critical patent/AU2019243315A1/en
Priority to AU2025256224A priority Critical patent/AU2025256224A1/en
Abandoned legal-status Critical Current

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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0602—Vertebrate cells
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AU2019243315A 2018-03-29 2019-03-28 Engineered immune effector cells and use thereof Abandoned AU2019243315A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025256224A AU2025256224A1 (en) 2018-03-29 2025-10-24 Engineered immune effector cells and use thereof

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862649781P 2018-03-29 2018-03-29
US62/649,781 2018-03-29
US201862774052P 2018-11-30 2018-11-30
US62/774,052 2018-11-30
PCT/US2018/067289 WO2019126748A1 (en) 2017-12-22 2018-12-21 Enhanced immune effector cells and use thereof
AUPCT/US2018/067289 2018-12-21
PCT/US2019/024686 WO2019191495A1 (en) 2018-03-29 2019-03-28 Engineered immune effector cells and use thereof

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AU2025256224A Division AU2025256224A1 (en) 2018-03-29 2025-10-24 Engineered immune effector cells and use thereof

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AU2019243315A1 true AU2019243315A1 (en) 2020-09-24

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AU2025256224A Pending AU2025256224A1 (en) 2018-03-29 2025-10-24 Engineered immune effector cells and use thereof

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US (1) US20210024959A1 (https=)
EP (1) EP3775228B1 (https=)
JP (2) JP7575271B2 (https=)
KR (2) KR102817092B1 (https=)
CN (1) CN111954715A (https=)
AU (2) AU2019243315A1 (https=)
BR (1) BR112020019205A2 (https=)
CA (1) CA3093020A1 (https=)
IL (1) IL277611A (https=)
MX (1) MX2020009896A (https=)
SG (1) SG11202008977UA (https=)
WO (1) WO2019191495A1 (https=)

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WO2021178933A2 (en) 2020-03-06 2021-09-10 Metagenomi Ip Technologies, Llc Class ii, type v crispr systems
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
US11866726B2 (en) 2017-07-14 2024-01-09 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
IL316257A (en) 2017-12-22 2024-12-01 Fate Therapeutics Inc Enhanced immune effector cells and use thereof
CN110628821B (zh) * 2018-06-25 2022-02-18 首都医科大学宣武医院 一种细胞模型及其制备方法、应用
CA3110837A1 (en) 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
JP7595583B2 (ja) * 2019-04-30 2024-12-06 アタラ バイオセラピューティクス，インコーポレーテッド 抗原特異的ｃｄ１９標的化ｃａｒ－ｔ細胞
JP7728747B2 (ja) * 2019-08-23 2025-08-25 サナ バイオテクノロジー，インコーポレイテッド Ｃｄ２４発現細胞およびそれらの用途
EP4041759A4 (en) * 2019-10-07 2023-12-20 Fate Therapeutics, Inc. IMPROVED CHIMERIC ANTIGEN RECEPTOR FOR IMMUNE EFFECTOR CELL CULTURE AND USE THEREOF
EP4045539A4 (en) * 2019-10-17 2024-03-13 Fate Therapeutics, Inc. Enhanced chimeric antigen receptor for immune effector cell engineering and use thereof
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