JP2020522578A5 - - Google Patents

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Publication number
JP2020522578A5
JP2020522578A5 JP2020517761A JP2020517761A JP2020522578A5 JP 2020522578 A5 JP2020522578 A5 JP 2020522578A5 JP 2020517761 A JP2020517761 A JP 2020517761A JP 2020517761 A JP2020517761 A JP 2020517761A JP 2020522578 A5 JP2020522578 A5 JP 2020522578A5
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JP
Japan
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composition
less
skin
weight percent
cantharidin
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JP2020517761A
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English (en)
Japanese (ja)
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JP7280870B2 (ja
JP2020522578A (ja
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Priority claimed from PCT/US2018/036353 external-priority patent/WO2018226894A1/en
Publication of JP2020522578A publication Critical patent/JP2020522578A/ja
Publication of JP2020522578A5 publication Critical patent/JP2020522578A5/ja
Priority to JP2023008166A priority Critical patent/JP2023061951A/ja
Application granted granted Critical
Publication of JP7280870B2 publication Critical patent/JP7280870B2/ja
Priority to JP2025181036A priority patent/JP2026062626A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020517761A 2017-06-06 2018-06-06 皮膚障害の処置 Active JP7280870B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023008166A JP2023061951A (ja) 2017-06-06 2023-01-23 皮膚障害の処置
JP2025181036A JP2026062626A (ja) 2017-06-06 2025-10-27 皮膚障害の処置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762516061P 2017-06-06 2017-06-06
US62/516,061 2017-06-06
PCT/US2018/036353 WO2018226894A1 (en) 2017-06-06 2018-06-06 Treatment of cutaneous disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023008166A Division JP2023061951A (ja) 2017-06-06 2023-01-23 皮膚障害の処置

Publications (3)

Publication Number Publication Date
JP2020522578A JP2020522578A (ja) 2020-07-30
JP2020522578A5 true JP2020522578A5 (https=) 2021-07-26
JP7280870B2 JP7280870B2 (ja) 2023-05-24

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ID=64565991

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020517761A Active JP7280870B2 (ja) 2017-06-06 2018-06-06 皮膚障害の処置
JP2023008166A Pending JP2023061951A (ja) 2017-06-06 2023-01-23 皮膚障害の処置
JP2025181036A Pending JP2026062626A (ja) 2017-06-06 2025-10-27 皮膚障害の処置

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023008166A Pending JP2023061951A (ja) 2017-06-06 2023-01-23 皮膚障害の処置
JP2025181036A Pending JP2026062626A (ja) 2017-06-06 2025-10-27 皮膚障害の処置

Country Status (9)

Country Link
US (2) US11147790B2 (https=)
EP (1) EP3634370A4 (https=)
JP (3) JP7280870B2 (https=)
KR (2) KR20250008976A (https=)
CN (1) CN111278414A (https=)
AU (2) AU2018281313B2 (https=)
IL (2) IL270900B2 (https=)
MX (2) MX393574B (https=)
WO (1) WO2018226894A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105636637A (zh) * 2013-08-21 2016-06-01 威瑞卡制药公司 用于治疗皮肤病症的组合物、方法和系统
EP3247996A4 (en) 2015-01-20 2019-01-02 Verrica Pharmaceuticals, Inc. Quantification and preparation of pharmaceutical grade cantharidin
AU2018281313B2 (en) 2017-06-06 2024-05-02 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
EP3638356A1 (en) 2017-06-15 2020-04-22 Verrica Pharmaceuticals, Inc. Devices and methods for the treatment of body surface disorders
USD900312S1 (en) 2017-06-15 2020-10-27 Verrica Pharmaceuticals, Inc. Applicator
KR102765631B1 (ko) 2017-10-04 2025-02-11 베리카 파마슈티컬스 인크. 칸타리딘의 합성

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US600556A (en) 1898-03-15 Pyroxylin compound
US1744893A (en) 1926-10-02 1930-01-28 George N Hein Hypodermic syringe
CH204207A (de) 1938-03-10 1939-04-30 Richard Graebener Fa Flaschenverschluss.
GB587994A (en) 1945-01-01 1947-05-12 Harry Milman Bickle Improvements relating to stoppers for bottles and other containers
GB1021968A (en) 1964-12-04 1966-03-09 Mini Cleans Ltd Liquid applicator
US3981924A (en) 1974-04-22 1976-09-21 International Flavors & Fragrances Inc. Diels-Alder adduct product
JPS51141863A (en) 1975-06-02 1976-12-07 Nippon Nohyaku Co Ltd Process for preparing organo-phosphoric acid esters
IL51209A (en) 1976-03-25 1981-02-27 Baxter Travenol Lab Blood filter
AU512465B2 (en) 1977-01-05 1980-10-09 Basf Aktiengesellschaft Manufacture of 3-halosulfonylthiophene-carboxylic acid derivatives
US4148887A (en) 1977-06-13 1979-04-10 The Procter & Gamble Company Dermatological compositions
US4299006A (en) 1980-02-19 1981-11-10 Cruz Miguel M Elastic drip guard for paint brushes
US4298752A (en) 1980-09-19 1981-11-03 Regents Of The University Of California Cycloadduct precursors of cantharidin and method
US4413154A (en) 1982-09-27 1983-11-01 Mobil Oil Corporation Diels-Alder cyclodimerization over a carbon molecular sieve catalyst
US4895727A (en) 1985-05-03 1990-01-23 Chemex Pharmaceuticals, Inc. Pharmaceutical vehicles for exhancing penetration and retention in the skin
JPH07112446B2 (ja) 1989-12-28 1995-12-06 小川化工株式会社 頭髪用液体化粧料塗布具
JP3117502B2 (ja) 1991-08-27 2000-12-18 株式会社資生堂 皮膚外用剤
US5296234A (en) 1991-10-11 1994-03-22 Abbott Laboratories Holder and packaging for a hardened medicated matrix
JPH05255367A (ja) 1992-02-28 1993-10-05 Jitsuei O カンタリジン誘導体組成物の製造法及びそれを含む抗ウイルス剤
US5445462A (en) 1993-08-03 1995-08-29 Medi-Flex Hospital Products, Inc. Liquid applicator
AU7629694A (en) 1993-08-17 1995-03-14 Schering-Plough Healthcare Products, Inc. Compositions for treating corns, calluses and warts
US5464855A (en) 1994-08-09 1995-11-07 Warner-Lambert Company Thiophene-2-carboxamidotetrazoles and pharmaceutical use thereof
US5590780A (en) 1995-06-22 1997-01-07 Wheaton Holding, Inc. Unit dose assembly
FR2736622B1 (fr) 1995-07-12 1997-08-29 Oreal Dispositif de conditionnement et de distribution d'un produit liquide ou pateux avec applicateur en forme de dome
FR2754175B1 (fr) 1996-10-07 1999-07-02 Oreal Utilisation d'un organopolysiloxane de nature elastomerique associe a une phase organique dans un produit de demaquillage des ongles
US6030633A (en) 1998-05-18 2000-02-29 West Agro, Inc. Film-forming compositions for protecting animal skin
JPH11335303A (ja) 1998-05-26 1999-12-07 Lion Corp 苦味増強方法及び皮膚外用剤
US6066124A (en) 1998-11-24 2000-05-23 Caillouette; James C. Control of treatment fluid application to tissue
US6379342B1 (en) 1999-04-02 2002-04-30 Scion International, Inc. Ampoule for dispensing medication and method of use
USD436661S1 (en) 1999-05-20 2001-01-23 Melvin P Berry Suppository applicator
US6337076B1 (en) 1999-11-17 2002-01-08 Sg Licensing Corporation Method and composition for the treatment of scars
US20030072814A1 (en) * 1999-12-16 2003-04-17 Maibach Howard I. Topical pharmaceutical composition for the treatment of warts
JP2001245964A (ja) 2000-03-02 2001-09-11 Lion Corp 芳香・消臭剤
FR2808662B1 (fr) 2000-05-09 2002-12-20 Delviel Systeme d'application d'une composition sur un element de surface
DE20016131U1 (de) 2000-09-16 2000-11-23 Aesculap AG & Co. KG, 78532 Tuttlingen Applikator für Gewebekleber
ATE390921T1 (de) 2001-05-31 2008-04-15 Univ Hong Kong Chinese Zusammensetzung mit demethylcantharidin in kombination mit platinhaltigen antikrebsmitteln und ihre verwendung
US6899897B2 (en) 2001-06-18 2005-05-31 Jaleva, Inc. Gum resin as a carrier for topical application of pharmacologically active agents
US6547467B2 (en) 2001-08-29 2003-04-15 Closure Medical Corporation Microapplicators, delivery systems and methods for adhesives and sealants
US6673031B2 (en) 2001-09-25 2004-01-06 Phillip Mark Liquid applicator
MXPA04003625A (es) 2001-10-19 2004-12-02 Sotechnika Inc Sintesis de analogos de ciclosporina.
JP4739621B2 (ja) 2001-12-25 2011-08-03 株式会社ダイヘン 消耗電極式アーク溶接装置
US20040011830A1 (en) 2002-07-17 2004-01-22 Kim Su Heon Dosing dispenser including multifunction cap
JP2004059446A (ja) 2002-07-25 2004-02-26 Mitsui Chemicals Inc 脂環式化合物及びその製造方法
US20040162533A1 (en) 2003-02-06 2004-08-19 Alley Kenneth A. Applicator device
CA2520921A1 (en) 2003-03-31 2004-10-21 Nick J. Manesis Multi-dose liquid dispensing assembly
RU2326893C2 (ru) 2003-04-16 2008-06-20 Кориум Интернэшнл Ковалентное и нековалентное сшивание гидрофильных полимеров и адгезивные композиции, полученные с ними
US7909808B2 (en) 2003-06-13 2011-03-22 Medlogic Global Limited Dual-ended applicator for dispensing two fluids
US20050019418A1 (en) 2003-07-23 2005-01-27 Crutchfield Charles E. Wart treatment
US20070111954A1 (en) 2003-07-23 2007-05-17 Cuticeuticals, Inc. Apparatus and method of wart treatment
KR20050032154A (ko) 2003-10-01 2005-04-07 나건연 약물, 화장품 도포기
JP2005187330A (ja) 2003-12-24 2005-07-14 Lion Corp 歯牙貼布用製品及びゲル組成物の選定方法
FR2865360B1 (fr) 2004-01-22 2006-05-26 Oreal Applicateur comportant un element d'application solidaire, lors de l'utilisation, d'un recipient contenant un produit a appliquer
FR2872704B1 (fr) 2004-07-12 2007-11-02 Laurent Schwartz Pluritherapie contre le cancer
US20060110415A1 (en) 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
US20050111900A1 (en) 2004-11-30 2005-05-26 Francesca Fazzolari Ampoule and method of use
US7846140B2 (en) 2004-11-30 2010-12-07 James Hagele Mini eye drop tip
FR2885779B1 (fr) 2005-05-23 2007-08-10 Oreal Dispositif de conditionnement et d'application d'un produit cosmetique ou dermatologique
US20070187437A1 (en) 2006-02-10 2007-08-16 Nordson Corporation Dispensing tip for liquid dispensing systems and method of making the same
US20070275045A1 (en) * 2006-02-28 2007-11-29 Evans Robin D Composition for the treatment of warts and molluscum contagiosum
US7563256B2 (en) 2006-03-30 2009-07-21 Isaac Hearne Cannula tip eye drop dispenser
JP5132071B2 (ja) 2006-03-31 2013-01-30 小林製薬株式会社 皮膚外用剤
US7758553B2 (en) 2006-04-03 2010-07-20 Insight Vision Incorporated Drop dispenser for the delivery of uniform droplets of viscous liquids
CN101453923A (zh) 2006-05-29 2009-06-10 三菱铅笔株式会社 涂敷工具及涂敷物质容器
DE102006034272A1 (de) 2006-07-18 2008-01-24 Aesculap Ag & Co. Kg Flüssigkeitsspender in der Medizin in Form einer Handhabe sowie dessen Verwendung
CN100465176C (zh) 2006-08-18 2009-03-04 芜湖天远科技开发有限责任公司 一种提取斑蝥素的方法
US20080146674A1 (en) 2006-12-15 2008-06-19 Rosenberg E William Use of gentian violet in treatment of atopic dermatitis
US8518076B2 (en) 2007-01-08 2013-08-27 Advanced Medical Solutions (Plymouth) Limited Surgical adhesive applicator
US8262608B2 (en) 2007-01-25 2012-09-11 Hyperbranch Medical Technology, Inc. Applicators for multiple component formulations and the like, and methods of use thereof
CN100545164C (zh) 2007-02-13 2009-09-30 北京世纪博康医药科技有限公司 斑蝥酸钠的制备工艺
KR101329489B1 (ko) 2007-04-04 2013-11-13 엘지전자 주식회사 냉장고용 홈바
CN101036774B (zh) 2007-04-17 2010-12-29 贵州益佰制药股份有限公司 一种复方斑蝥口服制剂的检测方法
KR100786203B1 (ko) 2007-05-14 2007-12-17 이민영 순간 접착제 용기
CN101108853B (zh) 2007-07-27 2010-05-26 贵州大学 斑蝥素分离纯化方法
CN101108854B (zh) 2007-07-27 2010-05-26 贵州大学 一种斑蝥素分离纯化方法
CN100577665C (zh) 2007-08-16 2010-01-06 广东药学院 一种抗肿瘤活性斑蛰素衍生物及其制备方法
DE102007046600A1 (de) 2007-09-27 2009-04-02 Linhardt Metallwarenfabrik Gmbh & Co Kg Verfahren zum Applizieren eines flüssigen, medizinischen Behandlungsmediums auf einen zu behandelden Bereich sowie Medizinprodukt
WO2009072007A2 (en) * 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
CN102149824A (zh) 2008-07-03 2011-08-10 阿莱洛吉克生物科学公司 保护亲核基团的组合物和方法
WO2010079513A2 (en) * 2009-01-07 2010-07-15 Sanjay Banerji Painless treatment of warts, corns & callus
US9480691B1 (en) 2009-01-20 2016-11-01 Hill Dermaceuticals, Inc. Topical liquid containing refined peanut oil for treating skin proliferation or inflammation disorders
JP5396125B2 (ja) 2009-03-30 2014-01-22 有限会社日本健康科学研究センター 被膜形成型製剤
EP2437596B1 (en) 2009-06-03 2017-05-03 Ex-Tek, LLC Skin treatment compositions
US20110071136A1 (en) 2009-09-16 2011-03-24 Cylene Pharmaceuticals, Inc Novel tricyclic protein kinase modulators
MX2012004144A (es) 2009-10-08 2012-05-08 Msd Consumer Care Inc Composicion de bajo contenido de eter y aparato de administracion.
CN101798309A (zh) 2009-12-04 2010-08-11 南京泽朗医药科技有限公司 一种从斑蝥中制备斑蝥素的方法
US9918991B2 (en) 2010-01-14 2018-03-20 Hydromer, Inc. Topical antimicrobial compositions and methods of using same
US20120016320A1 (en) 2010-07-13 2012-01-19 Lin Michael T Method and Device for Liquid Delivery
JP5736730B2 (ja) 2010-10-29 2015-06-17 王子ホールディングス株式会社 粘着シート
US20120148520A1 (en) 2010-12-10 2012-06-14 Michael Strobel Organic Iodine Complex Durable Barrier With Antimicrobial Preparations
FR2972928B1 (fr) 2011-03-25 2013-11-29 Urgo Lab Composition contenant une cellulose, une huile vegetale et un solvant volatil, ses utilisations comme pansement
US20120312709A1 (en) 2011-04-12 2012-12-13 Velcera, Inc. Device for storing and dispensing a medicament, and packaging for containing the same
CN102146086B (zh) 2011-04-12 2012-03-07 贵州金桥药业有限公司 一种斑蝥酸钠的制备方法
US9486829B2 (en) 2011-06-04 2016-11-08 Optmed, Inc. Applicator
CN102268006B (zh) 2011-06-15 2013-08-14 北京联合大学生物化学工程学院 一种复合酶提取斑蝥素的方法
US8871801B2 (en) * 2011-08-01 2014-10-28 Jacob LEVITT Method of treating acquired perforating dermatosis with cantharidin
CN102336765A (zh) 2011-10-11 2012-02-01 江苏四环生物股份有限公司 从斑蝥中提取斑蝥素的方法
CN102526146B (zh) 2012-01-13 2014-02-26 苏州大学 含有人参皂苷和斑蝥素的药物组合物及其用途
JP6215924B2 (ja) 2012-06-19 2017-10-18 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 新規の二環式チオフェニルアミド化合物
CN202730045U (zh) 2012-08-13 2013-02-13 遵义医学院 一种斑蝥素分离纯化的装置
CN202920809U (zh) 2012-09-27 2013-05-08 合肥诚者成医药科技有限公司 一种治疗尖锐湿疣的软膏
US9463180B2 (en) 2013-03-14 2016-10-11 Quadex Pharmaceuticals, Llc Treatment of molluscum contagiosum
CN105636637A (zh) * 2013-08-21 2016-06-01 威瑞卡制药公司 用于治疗皮肤病症的组合物、方法和系统
CA2946568C (en) 2014-04-21 2020-07-07 Aclaris Therapeutics, Inc. Peroxide formulations and methods and applicators for using the same
CN103923095A (zh) 2014-04-23 2014-07-16 遵义医学院 一种去甲基斑蝥素酸钙
EP3167914B1 (en) 2014-07-11 2021-09-29 Menicon Co., Ltd. Visibility-ensuring material, and device for discharging visibility-ensuring material
WO2016061193A1 (en) 2014-10-15 2016-04-21 Lixte Biotechnology, Inc. Process of synthesizing 3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1] heptane-2-carboxylic acid
CA2971279C (en) 2014-12-17 2023-09-19 Matthew Davidson Commercially viable synthesis of cantharidin and bioactive cantharidin derivatives
EP3247996A4 (en) 2015-01-20 2019-01-02 Verrica Pharmaceuticals, Inc. Quantification and preparation of pharmaceutical grade cantharidin
EP3258908A4 (en) * 2015-02-20 2018-08-22 Pedicis Research LLC Compositions and methods for treatment of skin infections
CN204817029U (zh) 2015-06-30 2015-12-02 厦门建霖工业有限公司 一种过滤式保健莲蓬臂
USD771250S1 (en) 2015-12-22 2016-11-08 Adhezion Biomedical, Llc Liquid dispenser with an extended tip
USD772407S1 (en) 2015-12-22 2016-11-22 Adhezion Biomedical, Llc Liquid dispenser having a tapered tip
JP6903062B2 (ja) 2016-01-25 2021-07-14 ポレックス コーポレーション 複数要素の焼結多孔質液体アプリケータニブ
USD801830S1 (en) 2016-05-19 2017-11-07 Adhezion Biomedical, Llc Liquid dispenser
CN106674248B (zh) 2016-12-17 2019-02-26 重庆市中药研究院 一种斑蝥素的合成工艺
AU2018281313B2 (en) 2017-06-06 2024-05-02 Verrica Pharmaceuticals Inc. Treatment of cutaneous disorders
USD900312S1 (en) 2017-06-15 2020-10-27 Verrica Pharmaceuticals, Inc. Applicator
EP3638356A1 (en) 2017-06-15 2020-04-22 Verrica Pharmaceuticals, Inc. Devices and methods for the treatment of body surface disorders
KR102765631B1 (ko) 2017-10-04 2025-02-11 베리카 파마슈티컬스 인크. 칸타리딘의 합성
USD868160S1 (en) 2018-03-26 2019-11-26 Robert Lam Multi-nib marker
US20190315151A1 (en) 2018-04-17 2019-10-17 Crayola Llc Ink-based marking device having a multi-component nib structure
USD938587S1 (en) 2018-06-11 2021-12-14 Terumo Cardiovascular Systems Corporation Dissector cone for endoscope
USD933494S1 (en) 2018-07-10 2021-10-19 Aptar Radolfzell Gmbh Packaging bottle for liquids
US12414761B2 (en) 2018-07-19 2025-09-16 Sanulus Medical, LLC Devices and methods for targeted delivery of a substance
USD947027S1 (en) 2020-02-11 2022-03-29 B.R. Tenant, Inc. Spout for a container
USD957625S1 (en) 2020-04-29 2022-07-12 Susan Reynolds Syringe

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